For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAKYAAPGTEGSAVTFAPRYDNFIGGEWVAPADGQYFENASPIDGKVFTRVARGTAPDIEKALDAAHAAA EAWGNTSAAERSNALLRIADRMEQHIERLAVAETWDNGKPIRESLNADIPLAIDHFRYFAGVLRAQEGSI SEIDHDTVAYHFHEPLGVVGQIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPASILVLMELIADLLP SGTVNVVNGFGVEAGKPLASSPRIAKIAFTGETTTGRLIMQYATENIIPVTLELGGKSPNIFMPDVMAAD DAFLDKALEGFTMFALNQGEVCTCPSRALVHASIYDEFIARAITRVEAIVGGDPLDEDTMIGAQASNDQY EKILSYIDIGRQEGAQVLTGGDARKVSEYPDGAYIQPTVFAGTNNMRIFQEEIFGPVLSVAKFDSLDEAL KIANDTLYGLGAGVWSRDMTNAYRLGRGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGRENHKMMLDHYQQ TKNILVSYSPDAAGFF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0972 | - | - | 100% (506) | putative aldehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2792c | - | 0.0 | 73.41% (504) | aldehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3328 | - | 4e-82 | 37.71% (480) | gamma-aminobutyraldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0467 | - | 0.0 | 70.02% (507) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4952 | - | 0.0 | 75.15% (507) | aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0458 | - | 0.0 | 70.02% (507) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 4e-53 | 32.51% (446) | succinic semialdehyde dehydrogenase |
| M. marinum M | MMAR_4912 | - | 0.0 | 74.75% (507) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4691 | - | 0.0 | 72.19% (507) | eptc-inducible aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0900 | - | 0.0 | 74.75% (507) | eptc-inducible aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3284 | - | 0.0 | 75.71% (494) | PUTATIVE eptc-inducible aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_0494 | - | 0.0 | 75.15% (507) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1468 | - | 0.0 | 76.13% (507) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0467|M.bovis_AF2122/97 MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
Rv0458|M.tuberculosis_H37Rv MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCE
MAV_4691|M.avium_104 MTVFARPGSAGALMSYESRYDNFIGGQWVAPARGRYFENPTPVTGQTFCE
MSMEG_0900|M.smegmatis_MC2_155 MTVFSRPGAADARMSFESRYDNFIGGEWVAPVDGRYFENPTPVTGQVFCE
TH_3284|M.thermoresistible__bu -------------MSFESRYDNFIGGEWVAPVGGEYFENPSPVTGQPFCE
Mflv_4952|M.gilvum_PYR-GCK MTVYARPGADGSLMSFKPRYDNFIGGQWVAPTAGRYFENPSPVTGQPFTE
Mvan_1468|M.vanbaalenii_PYR-1 MTVYARPGADGSLMSFKPRYDNFIGGQWVAPNAGRYFENPSPVTGQPFTE
MMAR_4912|M.marinum_M MTVFARPGAHSSLMTFESRYGNFIGGEWVAPAAGEYFEDLTPVTGAPFCE
MUL_0494|M.ulcerans_Agy99 MTVFARPGVHSSLMTFESRYDNFIGGEWVAPAAGEYFEDLTPVTGAPFCE
MAB_0972|M.abscessus_ATCC_1997 MAKYAAPGTEGSAVTFAPRYDNFIGGEWVAPADGQYFENASPIDGKVFTR
MLBr_02573|M.leprae_Br4923 ----------------------------------MSIATINPATGETVKT
: .* * .
Mb0467|M.bovis_AF2122/97 VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
Rv0458|M.tuberculosis_H37Rv VPRSDAADIDKALDAAHAAAPGWGKTAPAERAAILNMIADRIDKNAAALA
MAV_4691|M.avium_104 VARSDEADVDKALDAAHAAAPAWGKTAPPERAAILNKIADRIEENLESLA
MSMEG_0900|M.smegmatis_MC2_155 VARSSSADIEKALDAAHAAAPAWGKTAPAERALILNRIADRMEQNLEALA
TH_3284|M.thermoresistible__bu VARSTEADIDKALDAAHAAAPAWGKTAPAERALILNRIADRIEANLESIA
Mflv_4952|M.gilvum_PYR-GCK VARSDEADIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
Mvan_1468|M.vanbaalenii_PYR-1 VARSDESDIEKALDAAHAAAPAWGKTSAAERAVILNKIADRIEENLESIA
MMAR_4912|M.marinum_M VPRSTDVDVEKALDAAHAAAPAWGKAAPAERAAILHKIADRMEANLEALA
MUL_0494|M.ulcerans_Agy99 VPRSTDVDVEKALDAAHAAAPAWGKAAPAERATILHKIADRMEANLEALA
MAB_0972|M.abscessus_ATCC_1997 VARGTAPDIEKALDAAHAAAEAWGNTSAAERSNALLRIADRMEQHIERLA
MLBr_02573|M.leprae_Br4923 FTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLLEAEANQSA
.. :::.*: *:* : ::: .:*: ** :: . *
Mb0467|M.bovis_AF2122/97 VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
Rv0458|M.tuberculosis_H37Rv VAEVWDNGKPVREALAADIPLAVDHFRYFAA---AIRAQEGALSQIDEDT
MAV_4691|M.avium_104 VAEVWDNGKPIREALAADIPLAADHFRYFAG---ALRAQEGSLSQIDDDT
MSMEG_0900|M.smegmatis_MC2_155 LAEAWDNGKPIRETLNADIPLAIDHFRYFAS---AIRAQEGSLSQVDEDT
TH_3284|M.thermoresistible__bu LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSQIDDDT
Mflv_4952|M.gilvum_PYR-GCK LAESWDNGKPIRETLNADLPLAVDHFRYFAG---CIRAQEGSLSEVDADT
Mvan_1468|M.vanbaalenii_PYR-1 LAESWDNGKPIRETLNADIPLAVDHFRYFAG---AIRAQEGSLSEIDDDT
MMAR_4912|M.marinum_M LAESWDNGKPIRETLNADIPLAIDHFRYFAG---AIRAQEGSLSQIDSDT
MUL_0494|M.ulcerans_Agy99 LAESWDNGKPIREALNADIPLAIDHFRYFAG---AIRAQEGSLSQIDSDT
MAB_0972|M.abscessus_ATCC_1997 VAETWDNGKPIRESLNADIPLAIDHFRYFAG---VLRAQEGSISEIDHDT
MLBr_02573|M.leprae_Br4923 ALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVGAS
: **.::.: : * . ***:* : *:* : : :
Mb0467|M.bovis_AF2122/97 VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
Rv0458|M.tuberculosis_H37Rv VAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPAS
MAV_4691|M.avium_104 VAYHFHEPLGVVGQIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPVS
MSMEG_0900|M.smegmatis_MC2_155 VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPAS
TH_3284|M.thermoresistible__bu VAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPAS
Mflv_4952|M.gilvum_PYR-GCK VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPAS
Mvan_1468|M.vanbaalenii_PYR-1 VAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPAS
MMAR_4912|M.marinum_M VAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPAS
MUL_0494|M.ulcerans_Agy99 VAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPAS
MAB_0972|M.abscessus_ATCC_1997 VAYHFHEPLGVVGQIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPAS
MLBr_02573|M.leprae_Br4923 KALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQC
* ::***** ::*****: . **** *** :** *.:.* .
Mb0467|M.bovis_AF2122/97 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
Rv0458|M.tuberculosis_H37Rv VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFTGETTTGR
MAV_4691|M.avium_104 VLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSNRIAKIAFTGETTTGR
MSMEG_0900|M.smegmatis_MC2_155 VLYLMSLIADLVPAGVVNIVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
TH_3284|M.thermoresistible__bu VMYLMSLIGDLLPPGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mflv_4952|M.gilvum_PYR-GCK ILYLMEVIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
Mvan_1468|M.vanbaalenii_PYR-1 ILYLMELIADLLPAGVINVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MMAR_4912|M.marinum_M ILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MUL_0494|M.ulcerans_Agy99 ILYLMSLIGDLLPAGVVNVVNGFGVEAGKPLASSNRIAKIAFTGETTTGR
MAB_0972|M.abscessus_ATCC_1997 ILVLMELIADLLPSGTVNVVNGFGVEAGKPLASSPRIAKIAFTGETTTGR
MLBr_02573|M.leprae_Br4923 ALYLADVIARGGFPEDCFQTLLISANGVEAILRDPRVAAATLTGSEPAGQ
: * .:*. . . :..:. :.: . *:* ::**. .:*:
Mb0467|M.bovis_AF2122/97 LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
Rv0458|M.tuberculosis_H37Rv LIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALN
MAV_4691|M.avium_104 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAKADDYQDKALEGFTMFALN
MSMEG_0900|M.smegmatis_MC2_155 LIMQYASQNLIPVTLELGGKSPNIFFSDVMAAADDFQDKALEGFTMFALN
TH_3284|M.thermoresistible__bu LIMQYASQNLIPVTLELGGKSPNIFFADVMAASDDFCDKALEGFTMFALN
Mflv_4952|M.gilvum_PYR-GCK LIMQYASQNLIPVTLELGGKSPNIFFNDVLAASDDYQDKALEGFTMFALN
Mvan_1468|M.vanbaalenii_PYR-1 LIMQYASQNLIPVTLELGGKSPNIFFNDVLAQADNYQDKALEGFTMFALN
MMAR_4912|M.marinum_M LIMQYASQNLIPVTLELGGKSPNIFFSDVLAAHDDYQDKALEGFTMFALN
MUL_0494|M.ulcerans_Agy99 LIMQYASQNLIPVTLELGGKSPNIFFPDVLAAHDDYQDKALEGFTMFALN
MAB_0972|M.abscessus_ATCC_1997 LIMQYATENIIPVTLELGGKSPNIFMPDVMAADDAFLDKALEGFTMFALN
MLBr_02573|M.leprae_Br4923 AVGAIAGNEIKPTVLELGGSDPFIVMP-----SADLDAAVATAVTGRVQN
: * .:: *..*****..* *.: . ..* . *
Mb0467|M.bovis_AF2122/97 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
Rv0458|M.tuberculosis_H37Rv QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDTETMLGSQASN
MAV_4691|M.avium_104 QGEVCTCPSRSLIQADIYDEFLELAAIRTKAVRQGDPLDSETMLGSQASN
MSMEG_0900|M.smegmatis_MC2_155 QGEVCTCPSRSLIQSDIFDEFLELAAIRTKAVRQGDPLDTETMIGSQASN
TH_3284|M.thermoresistible__bu QGEVCTCPSRSLIQADIYDEFLELATIRTKAVRQGDPLDTETMVGAQASN
Mflv_4952|M.gilvum_PYR-GCK QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
Mvan_1468|M.vanbaalenii_PYR-1 QGEVCTCPSRSLIQADIYDEFLALAAIRTKAVRQGDPLDTETMIGAQASN
MMAR_4912|M.marinum_M QGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETMIGAQASN
MUL_0494|M.ulcerans_Agy99 QGEVCTCPSRGLIQADIYDRFLELAAIRTKAVRQGDPLDTETMIGAQASN
MAB_0972|M.abscessus_ATCC_1997 QGEVCTCPSRALVHASIYDEFIARAITRVEAIVGGDPLDEDTMIGAQASN
MLBr_02573|M.leprae_Br4923 NGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATE
:*: * ...* : ::.*:*.*: * ::: *** * :* :*. *::
Mb0467|M.bovis_AF2122/97 DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
Rv0458|M.tuberculosis_H37Rv DQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNM
MAV_4691|M.avium_104 DQLEKVLSYIAIGKDEGATIITGGERAELGGDLSGGFYMQPTIFAGNNKM
MSMEG_0900|M.smegmatis_MC2_155 DQFEKILSYIEIGKSEGARIVTGGERADLGGDLSGGYYIQPTIFTGHNKM
TH_3284|M.thermoresistible__bu DQLEKILSYIDIGRSEGATVVTGGERAELGGDLSGGYYVQPTIFTGDNSM
Mflv_4952|M.gilvum_PYR-GCK DQLEKILSYIEIGKSEGAKVVTGGERAELGGDLNGGYYVAPTIFTGNNTM
Mvan_1468|M.vanbaalenii_PYR-1 DQLEKILSYIEIGKSEGAQVVTGGERAELGGDLNGGYYVAPTIFTGHNKM
MMAR_4912|M.marinum_M DQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTIFEGTNNM
MUL_0494|M.ulcerans_Agy99 DQLQKILSYIEIGKEEGARVVTGGERCELGGDLNGGYYVQPTIFEGTNNM
MAB_0972|M.abscessus_ATCC_1997 DQYEKILSYIDIGRQEGAQVLTGGDARKVS-EYPDGAYIQPTVFAGTNNM
MLBr_02573|M.leprae_Br4923 SGRAQVEQQVDAAAAAGAVIRCGGK----RPDRPGWFYPPTVITDITKDM
. :: . : . ** : **. : . * ..: : *
Mb0467|M.bovis_AF2122/97 RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
Rv0458|M.tuberculosis_H37Rv RIFKEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAG
MAV_4691|M.avium_104 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
MSMEG_0900|M.smegmatis_MC2_155 RIFQEEIFGPVVAVTSFSDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
TH_3284|M.thermoresistible__bu RIFQEEIFGPVVAVTSFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
Mflv_4952|M.gilvum_PYR-GCK RIFQEEIFGPVVAVTSFTDYDDAISLANDTLYGLGAGVWSRNGNTAYRAG
Mvan_1468|M.vanbaalenii_PYR-1 RIFQEEIFGPVVAVTSFTDYDDAISIANDTLYGLGAGVWSRDGNTAYRAG
MMAR_4912|M.marinum_M RIFQEEIFGPVVSVTSFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
MUL_0494|M.ulcerans_Agy99 RIFQEEIFGPVVSVTLFTDYDDAIRIANDTLYGLGAGVWSRDGNTAYRAG
MAB_0972|M.abscessus_ATCC_1997 RIFQEEIFGPVLSVAKFDSLDEALKIANDTLYGLGAGVWSRDMTNAYRLG
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFI
:: :*:**** :* . *:*: :** * :***:..*::: . :
Mb0467|M.bovis_AF2122/97 RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
Rv0458|M.tuberculosis_H37Rv RDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGREGHQMMLQHYQHTKNLLV
MAV_4691|M.avium_104 RDIQAGRVWVNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNMLV
MSMEG_0900|M.smegmatis_MC2_155 RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
TH_3284|M.thermoresistible__bu RDIKAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHTMMLDHYQQTKNLLV
Mflv_4952|M.gilvum_PYR-GCK RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHRMMLDHYQQTKNLLV
Mvan_1468|M.vanbaalenii_PYR-1 RDIKAGRVWTNCYHQYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MMAR_4912|M.marinum_M RDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MUL_0494|M.ulcerans_Agy99 RDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNLLV
MAB_0972|M.abscessus_ATCC_1997 RGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGRENHKMMLDHYQQTKNILV
MLBr_02573|M.leprae_Br4923 DNIVAGQVFINGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWI
.* **:*: * .. .*** *:** *** : .: : *.: :
Mb0467|M.bovis_AF2122/97 SYSDKALGFF
Rv0458|M.tuberculosis_H37Rv SYSDKALGFF
MAV_4691|M.avium_104 SYSNKAQGFF
MSMEG_0900|M.smegmatis_MC2_155 SYSDKAQGFF
TH_3284|M.thermoresistible__bu SYSTKAQGFF
Mflv_4952|M.gilvum_PYR-GCK SYSDQALGFF
Mvan_1468|M.vanbaalenii_PYR-1 SYSDKALGFF
MMAR_4912|M.marinum_M SYGSKAQGFF
MUL_0494|M.ulcerans_Agy99 SYGSKAQGFF
MAB_0972|M.abscessus_ATCC_1997 SYSPDAAGFF
MLBr_02573|M.leprae_Br4923 A---------
: