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SQHDSSSSAGSAPAIERRTIDVIPDEERHGSVRNQFTLWFGANTQITAIVDGALAVVFGADALWAIIGLL IGNILGGIVMALHSAQGPRMGLPQMISSRAQFGVHGAAIPLLLVVLMYLGFAATGSVLAGQAINEILHLG SSSAGILIFGALTAVIAVVGYRVIHVVGRIATVLGVVGFTYLAIRLFTQYDVSSVIGVVPFDFVTFLLAI SLSAGWQLTFGPYVADYSRYLPRSTSGRATFWSTFAGSVIGSQWSMTFGALVAAVAGDAFLGDQVGFVGG LAGSAALAVLIYLVIVVGKLTVNTLNAYGGFMCILTTVSGINGQTRIAPAVRAAYIVGFTAVSVAIAVVA SADFLDNFKNFVLVLLMVFTPWSAINLTDYYVISKERVDIPALYDPAGRYGSWNLPALACYVIGVVVQIP FLAQKLYTGPITNMLGGADISWIVGLVVTAALYYFVVGRRTNAPAEMIYPAKTPISV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1177 | - | - | 100% (478) | cytosine/purines/uracil/thiamine/allantoin permease family protein |
| M. smegmatis MC2 155 | MSMEG_1683 | - | 4e-97 | 41.43% (461) | cytosine/purine/uracil/thiamine/allantoin permease family |
| M. smegmatis MC2 155 | MSMEG_5653 | - | 2e-72 | 34.12% (466) | cytosine/purine/uracil/thiamine/allantoin permease family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3483 | - | 3e-06 | 23.32% (386) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0055 | - | 1e-34 | 25.05% (459) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2025 | - | 1e-30 | 25.20% (488) | purine/cytosine permease |
| M. marinum M | MMAR_1212 | - | 2e-10 | 23.24% (512) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 3e-05 | 19.91% (442) | hypothetical protein MUL_2680 |
| M. vanbaalenii PYR-1 | Mvan_3383 | - | 8e-39 | 26.64% (443) | permease for cytosine/purines, uracil, thiamine, allantoin |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1212|M.marinum_M --MIDTTAPHSPVHSPSHGAGPANIKPDYHPRLTNDDLAPLREQTWGTYN
MUL_2680|M.ulcerans_Agy99 --MIDTTAPHSPVHSPSHGAGPANIKPDYHPRLTNDDLAPLREQTWGTYN
MSMEG_1177|M.smegmatis_MC2_155 ------MSQHD--SSSSAGSAPAIER-------RTIDVIPDEERHGSVRN
MAB_2025|M.abscessus_ATCC_1997 ---MDEIQACCSATSLIASRESVGRDRVGAIERAGIDYLPEAARGSSPKN
Mflv_0055|M.gilvum_PYR-GCK ----------------------------MHDLEAELTVIPESAKTTDLRG
Mvan_3383|M.vanbaalenii_PYR-1 MPQTSPGSTTGALTGEVFSGHQPSGVGDLSVETHGIAPISGDHRYGSPGR
Mb3483|M.bovis_AF2122/97 -----MPGVITNSESPTAADHDRITATRETLEDYTLRLAPRSYRRWPPAV
. :
MMAR_1212|M.marinum_M IFAFWMSDVHSVGGYVTAGSLFALGLASWQVLVSLVIAITIVYFLCNLVA
MUL_2680|M.ulcerans_Agy99 IFAFWMSDVHSVGGYVTAGSLFALGLASWQVLVSLVIAITIVYFLCNLVA
MSMEG_1177|M.smegmatis_MC2_155 QFTLWFGANTQITAIVDGALAVVFGADALWAIIGLLIGNILGGIVMALHS
MAB_2025|M.abscessus_ATCC_1997 LFAVFVGGNLAFSTIIFGWLPIVMGLTFWQAVSSSVTGLLIGLMLTAPMS
Mflv_0055|M.gilvum_PYR-GCK QFWIWAGANIAPINWILGALGVTMGLGLFETIAVLVVGNAIGMSLFGTFV
Mvan_3383|M.vanbaalenii_PYR-1 LFTVWFAPQVNMSGVFTGTLAIVLGLGFWLGLLAMVIGTVLGSLVVGYLS
Mb3483|M.bovis_AF2122/97 VGISALGGIAYLADFAIG-ANVGITWGTANALCGIAIFALVVFVTGLPLA
. . . : : :
MMAR_1212|M.marinum_M RPSQATGVPYPVICR-TAFGVLGANIPAIIRGLIAVAWYGIQTYLASAAL
MUL_2680|M.ulcerans_Agy99 RPSQATGVPYPVICR-TAFGVLGANIPAIIRGLIAVAWYGIQTYLASAAL
MSMEG_1177|M.smegmatis_MC2_155 AQGPRMGLPQMISSR-AQFGVHGAAIPLLLVVLMYLGFAATGSVLAGQAI
MAB_2025|M.abscessus_ATCC_1997 LFGPRTGTNNPVSSG-AHFGVRGRLIGSSLTLMFALVYAAIAVWTSGEAL
Mflv_0055|M.gilvum_PYR-GCK VIGQKTGVTGMVLSR-MVFGRRGAYVPAAVQAALCIGWCAVNTWIVLDLV
Mvan_3383|M.vanbaalenii_PYR-1 TWGPRTGTGQLPNAR-MAFG-GTVVVPAALQWLSSIAWDALVGLFGGEAL
Mb3483|M.bovis_AF2122/97 YYAARYNIDLDLITRGSGFGYYGSVVTNVIFATFTFIFFALEGSIMAQGL
. . ** : : . : . :
MMAR_1212|M.marinum_M DVVMIKL---FPG--------LARYAVVEDYGFLGLPALGWASYLILWVL
MUL_2680|M.ulcerans_Agy99 DVVMIKL---FPG--------LARYAVVEDYGFLGLPALGWASYLILWVL
MSMEG_1177|M.smegmatis_MC2_155 NEILHLG---SSS--------AGILIFGALTAVIAVVGYRVIHVVGRIAT
MAB_2025|M.abscessus_ATCC_1997 IAGASRL---FGAPQNHVAFLLGYGVIALEVILIALYGHATIVWAQKIII
Mflv_0055|M.gilvum_PYR-GCK MALLGRIGLVDPELSNHAARIVVAGIIMTTQVVIAWFGYRLIAAFERWTV
Mvan_3383|M.vanbaalenii_PYR-1 SVLLGIP------------FWVAVLIVLGVQGVVGFFGYELIHRLQAVLT
Mb3483|M.bovis_AF2122/97 KLGLHIP------------LWAGYACSTLIIFPLVVYGMKVLSQLQLWTT
: .
MMAR_1212|M.marinum_M QACVFWRGMEAIRKFIDFCGPAVY-------VVMFALSGYLISKAGWAAI
MUL_2680|M.ulcerans_Agy99 QACVFWRGMEAIRKFIDFCGPAVY-------VVIFALSGYLISTAGWAAI
MSMEG_1177|M.smegmatis_MC2_155 VLGVVGFTYLAIRLFTQYDVSSVIG------VVPFDFVTFLLAISLSAGW
MAB_2025|M.abscessus_ATCC_1997 PLAVVVLALGVLAYAPNFHPMGSAQ---HGYALQEFWPTWLFAVTVSVGG
Mflv_0055|M.gilvum_PYR-GCK PPTVAVLVAMTAVAWFGLDVDWGYTGDAALTGAEHFTAITAVMTAIGIGW
Mvan_3383|M.vanbaalenii_PYR-1 VVLFVTFLVFTAKLVAGHEIVVPAA-----VSGPDLVGAFVLEVTIAFSL
Mb3483|M.bovis_AF2122/97 PLWLILMAAPFGYLVVSHPDSIGQFFS--YAGKDGHGGLSFGSVLLAAGV
. .
MMAR_1212|M.marinum_M DLNLGDVRYSGWDAIPVMLG-AIALVVSYFSGPMLNFGDFSRYGRSFGAV
MUL_2680|M.ulcerans_Agy99 DLNLGDVRYSGWDAIPVMLG-AIALVVSYFSGPMLNFGDFSRYGRSFGAV
MSMEG_1177|M.smegmatis_MC2_155 QLTFGPYVADYSRYLPRSTS-GRATFWSTFAGSVIGSQWSMTFGALVAAV
MAB_2025|M.abscessus_ATCC_1997 PLSYAPSVGDYTRRISRSRYSDRQIAVAVSAGIFLGLFSTATFGAFTAST
Mflv_0055|M.gilvum_PYR-GCK GITWLGYAGDYSRFVSSSVP-ARKLFAASALGQFIPVVWLGALGATLATL
Mvan_3383|M.vanbaalenii_PYR-1 AISWATYAADFSRYLPADVS-PVRVFGFSTAGLALGYVFVQGVGIAAAGV
Mb3483|M.bovis_AF2122/97 CLSLIAQIAEQIDYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQII
:. . : : *
MMAR_1212|M.marinum_M RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELIT--------DPVQTVA
MUL_2680|M.ulcerans_Agy99 RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELIT--------DPVQTVA
MSMEG_1177|M.smegmatis_MC2_155 AGDAFLGDQVGFVGG---LAGSAALAVLIY--------------LVIVVG
MAB_2025|M.abscessus_ATCC_1997 FSAPTASYVADMVAT-----APGWYVVPLL--------------ILAVLG
Mflv_0055|M.gilvum_PYR-GCK SASSDPGEIIVDAYG--------VLAIPVL--------------LLVVHG
Mvan_3383|M.vanbaalenii_PYR-1 VGEHTVEGVRSVMGG-------GLLGGLAL--------------LVIAVA
Mb3483|M.bovis_AF2122/97 GLFLAVYLMANIPGSSTIANQPVHQFMQIYRTFVPGWLALTLAVILVILS
: .
MMAR_1212|M.marinum_M RIDSTFAIILGASTFTIATIGINIVANFISPAFD------FSNVNPQRIS
MUL_2680|M.ulcerans_Agy99 RIDSTFAIILGASTFTIATIGINIVANFISPAFD------FSNVNPQRIG
MSMEG_1177|M.smegmatis_MC2_155 KLTVNTLNAYGGFMCILTTVSGINGQTRIAPAV--------------RAA
MAB_2025|M.abscessus_ATCC_1997 GCGQGVISIYSSGLDLESIVPRLNRT---------------------QTT
Mflv_0055|M.gilvum_PYR-GCK PLATNILNIYTCAVSTQALDIHVNRR---------------------VLN
Mvan_3383|M.vanbaalenii_PYR-1 SIGSGVMNDYSGSLALQTLGVRVRRP------------------------
Mb3483|M.bovis_AF2122/97 QIKINVTNAYSGSLAWTNSFTRLTKHYPGRVVFLGVNLAIALILMEANMF
MMAR_1212|M.marinum_M WRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIADYY
MUL_2680|M.ulcerans_Agy99 WRTGGMIAAVGSALITPWNLYNHPDVIHYTLETLGAFIGPLFGVLIADYY
MSMEG_1177|M.smegmatis_MC2_155 YIVGFTAVSVAIAVVASADFLDN--FKNFVLVLLMVFT-PWSAINLTDYY
MAB_2025|M.abscessus_ATCC_1997 LIASGIAVVLMYLGVVVTDAIDS---VTGMTVVLNSFAGSWVAINICGFF
Mflv_0055|M.gilvum_PYR-GCK IVIGVVAMAWVVYFVLNGDFAAT---IDAWLVGIVGWLAPWAAVMLVHWF
Mvan_3383|M.vanbaalenii_PYR-1 -VSAVIVTVLAFALILWLHAADTATRFTDVLLLVSYWIPAFVAVVVVDWW
Mb3483|M.bovis_AF2122/97 DFLNTILGCYANCGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAIN
: : :
MMAR_1212|M.marinum_M LVRKQHVVVDDLFSLSHDGT---YWYRKGYNPAAVIATAVS----AAIAM
MUL_2680|M.ulcerans_Agy99 LVRKQHVVVDDLFSLSHDGT---YWYRKGYNPAAVIATAVS----AAIAM
MSMEG_1177|M.smegmatis_MC2_155 VISKERVDIPALYDPAGRYG---SWNLP-ALACYVIGVVVQ----IPFLA
MAB_2025|M.abscessus_ATCC_1997 KANRGQYDPKALQRFGQDGRGGLYWFSHGFNVRAVVPFIAGSGLGLLTVQ
Mflv_0055|M.gilvum_PYR-GCK GVARRQVDPATLLTPPNEST--LPAVRPSALISLAVGIVFT--WLFMYGM
Mvan_3383|M.vanbaalenii_PYR-1 RRAEGRPTVDPAAEVTGRRD------AVVALVVFVVSYLAA----IPFMN
Mb3483|M.bovis_AF2122/97 PVGFGSLLLAAGLSIVTFFGGLGAALQPYSPLVAIVTALVMP---PILAA
:
MMAR_1212|M.marinum_M VPVLASDVYGMYTAAEYSWFIGCGVALVVYYLLATRGRLAIAPPYHPVGA
MUL_2680|M.ulcerans_Agy99 APVLASDV------------------------------------------
MSMEG_1177|M.smegmatis_MC2_155 QKLYTGPITNMLGGADISWIVGLVVTAALYYFVVGRRTNAPAEMIYPAKT
MAB_2025|M.abscessus_ATCC_1997 NDLYQAPFANIAGGIDVSLLLSVVVGGGLYWLAQVS---WPAPRVVSSGS
Mflv_0055|M.gilvum_PYR-GCK VPMMQGPIAVALGGVDLSWLAGGLAAGSLYAALEIPKARRA---------
Mvan_3383|M.vanbaalenii_PYR-1 TSLIQGPVAMAWHGADIAYFVNLAVAAVLYGGYRLMSRD-----------
Mb3483|M.bovis_AF2122/97 ATKGKYYLRRTHDGIDLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQT
.
MMAR_1212|M.marinum_M G---------------------------------
MUL_2680|M.ulcerans_Agy99 ----------------------------------
MSMEG_1177|M.smegmatis_MC2_155 PISV------------------------------
MAB_2025|M.abscessus_ATCC_1997 SA--------------------------------
Mflv_0055|M.gilvum_PYR-GCK ----------------------------------
Mvan_3383|M.vanbaalenii_PYR-1 ----------------------------------
Mb3483|M.bovis_AF2122/97 HGAHVCSLCLSTDKQAEHVLPGLARAHIPGDQVP