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M. bovis AF2122 / 97 Mb3483 (-)

annotation: transmembrane protein
coordinates: 3822105 - 3823790
length: 561

MPGVITNSESPTAADHDRITATRETLEDYTLRLAPRSYRRWPPAVVGISALGGIAYLADFAIGANVGITW
GTANALCGIAIFALVVFVTGLPLAYYAARYNIDLDLITRGSGFGYYGSVVTNVIFATFTFIFFALEGSIM
AQGLKLGLHIPLWAGYACSTLIIFPLVVYGMKVLSQLQLWTTPLWLILMAAPFGYLVVSHPDSIGQFFSY
AGKDGHGGLSFGSVLLAAGVCLSLIAQIAEQIDYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQII
GLFLAVYLMANIPGSSTIANQPVHQFMQIYRTFVPGWLALTLAVILVILSQIKINVTNAYSGSLAWTNSF
TRLTKHYPGRVVFLGVNLAIALILMEANMFDFLNTILGCYANCGMAWVVAVASDIGFNKYLLGLSPKTPE
FRRGMLYAINPVGFGSLLLAAGLSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRRTHD
GIDLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQTHGAHVCSLCLSTDKQAEHVLPGLARAHIPGDQV
P
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3483--100% (561)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3454-0.099.76% (422) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2635c-0.072.34% (546) hypothetical protein MAB_2635c
M. marinum MMMAR_1096-0.085.90% (539) hypothetical protein MMAR_1096
M. avium 104-----
M. smegmatis MC2 155MSMEG_5653-5e-0723.61% (360) cytosine/purine/uracil/thiamine/allantoin permease family
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb3483|M.bovis_AF2122/97            MPGVITNSE-----SPTA-ADHDRITATRETLEDYTLRLAPRSYRRWPPA
Rv3454|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1096|M.marinum_M               MQDTDVSQV-----SPSAPADLAEITAAKETLEDYTLRFAPRSYRRWSPA
MAB_2635c|M.abscessus_ATCC_199      MTDTLDTTASAPVSSAPSSHDVAESAALRETLEDYTLRFAPRRFRRWSPA
MSMEG_5653|M.smegmatis_MC2_155      ------------------------MATDSATVESKSIDWIPLGERRGKPS
                                                                                      

Mb3483|M.bovis_AF2122/97            VVGISALGGIAYLADFAIGANVGITWGTANALCGIAIFALVVFVTGLPLA
Rv3454|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1096|M.marinum_M               VVGISALGGIAYLADFAIGANIGITWGTTNALWGIAIFAAVVFTTGLPLA
MAB_2635c|M.abscessus_ATCC_199      VVGVTALGGIAYLADFAIGANIGISYGTGNALWGIGVFAVIIILTGIPLS
MSMEG_5653|M.smegmatis_MC2_155      MLFPLWFMSNANLTTLATG-MVGASLGASFLTSLVAIVLGAAVGTVFTAF
                                                                                      

Mb3483|M.bovis_AF2122/97            YYAARYNIDL-DLITRGSGFGYYGSVVTNVIFATFTFIFFALEGSIMAQG
Rv3454|M.tuberculosis_H37Rv         ----------------------------------------------MAQG
MMAR_1096|M.marinum_M               YYAARYNIDL-DLITRGSGFGYYGSVVTNVIFATFTFIFFALEGSIMAQG
MAB_2635c|M.abscessus_ATCC_199      YYAARYNIDL-DLITRGSGFGYYGSIVTNIIYATFTFIFFALEGSIMAQG
MSMEG_5653|M.smegmatis_MC2_155      HSAQGPQLGLPQMIQSRAQFGYRGVVVICAVVIFSIVGFNIFNQILAGDV
                                                                                   .: 

Mb3483|M.bovis_AF2122/97            LKLGLHIPLW-AGYACSTLIIFPLVVYGMKVLSQLQLWTTPLWLILMAAP
Rv3454|M.tuberculosis_H37Rv         LKLGLHIPLW-AGYACSTLIIFPLVVYGMKVLSQLQLWTTPLWLILMAAP
MMAR_1096|M.marinum_M               LNLGLHIPLW-LGYAFSTLLIFPLVIYGMKVLSQLQLWTTPLWLILMVAP
MAB_2635c|M.abscessus_ATCC_199      LKLGLGVPLP-VGYAMSTIIIIPLVIYGMKALSVLQVWTTPLWLVMMVIP
MSMEG_5653|M.smegmatis_MC2_155      LTMTTGVDARNLWFVIITALALALAIYGYHWIHRVQNWLTWLFLATFGVF
                                    *.:   :      :.  * : :.*.:** : :  :* * * *:*  :   

Mb3483|M.bovis_AF2122/97            FGYLVVSHPDSIGQFFSYAGKDGHGGLSFGSVLLAAGVCLSLIAQIAEQI
Rv3454|M.tuberculosis_H37Rv         FGYLVVSHPDSIGQFFSYAGKDGHGGLSFGSVLLAAGVCLSLIAQIAEQI
MMAR_1096|M.marinum_M               FGYLLISHPESVAQFFAYAGKDGRATASIGSALMAAGVCLALIAQIAEQI
MAB_2635c|M.abscessus_ATCC_199      FVYLLVRHPDSIGAFFAYGGKDGQG-VNLGSIMLAAGVCLSLIAQIAEQI
MSMEG_5653|M.smegmatis_MC2_155      TVVALVTLHLPHGQFG-FAG------FSWPAFLVQFAAAAAYALGWAPYV
                                        ::    . . *  :.*       .  : ::  ... :     *  :

Mb3483|M.bovis_AF2122/97            -DYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQIIGLFLAVYLMAN
Rv3454|M.tuberculosis_H37Rv         -DYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQIIGLFLAVYLMAN
MMAR_1096|M.marinum_M               -DYLRFMPPRTPKNSRRWWAWMLLAGPGWVIFGAAKQIIGLFLAVYLLSN
MAB_2635c|M.abscessus_ATCC_199      -DYLRFMPPKTPENSRRWWTAMLLAGPGWVLFGAIKQVIGLFLAVYLIAN
MSMEG_5653|M.smegmatis_MC2_155      SDYSRYLPPQTSPGK------ALFYTYGGVFVGSSWLMILGAFVAALFAD
                                     ** *::**:*. .        *:   * * .*:   :*   :.. *:::

Mb3483|M.bovis_AF2122/97            IPGSSTIANQPVHQFMQIYRTFVP-GWLALTLAVILVILSQIKINVTNAY
Rv3454|M.tuberculosis_H37Rv         IPGSSTIANQPVHQFMQIYRTFVP-GWLALTLAVILVVLSQIKINVTNAY
MMAR_1096|M.marinum_M               VAGAADFANQPVHQFMQIYRNFMP-GWLALTLAVILVVLSQVKINVTNAY
MAB_2635c|M.abscessus_ATCC_199      VAGGATVANQPVHQFLEIYQNMMP-HWLAITLAVILVVISQIKINVTNAY
MSMEG_5653|M.smegmatis_MC2_155      VS--------PLEAVRQAADGILPGAGLWLLVAALPGLVTVITVNIYASS
                                    :.        *:. . :    ::*   * : :*.:  ::: :.:*:  : 

Mb3483|M.bovis_AF2122/97            SGSLAWTNSFTRLT---KHYPGRVVFLGVNLAIALILMEANMFDFLNTIL
Rv3454|M.tuberculosis_H37Rv         SGSLAWTNSFTRLT---KHYPGRVVFLGVNLAIALILMEANMFDFLNTIL
MMAR_1096|M.marinum_M               SGSLAWTNSFTRVT---KHYPGRVMFLGVNLTIALILMEANMFDFLNTIL
MAB_2635c|M.abscessus_ATCC_199      SGSLAWTNSFTRIT---KHYPGRLIFVLFNLLIALVLMEANMFDFLNTIL
MSMEG_5653|M.smegmatis_MC2_155      IELITIIDSFRAVSPTRRLRVGACVVIGLAGLLGAVLSTGEFLDNFGSFL
                                       ::  :**  ::   :   *  :.: .   :. :*  .:::* :.::*

Mb3483|M.bovis_AF2122/97            GCYANCGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAINPVGFGSL
Rv3454|M.tuberculosis_H37Rv         GCYANCGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAINPVGFGSL
MMAR_1096|M.marinum_M               GFYANCGMAWVVTVASDIVFNKFLLGLSPKTPEFRRGMLYAINPVGFGSM
MAB_2635c|M.abscessus_ATCC_199      GFYANCGMAWVVTVASDIAINKYLLKLSPKEPEFRRGMLYDVNPVGFVSM
MSMEG_5653|M.smegmatis_MC2_155      VILLYLLVPWTSVNLVDYYFVRRGRYAIGEIFVPRGGVYGTWGWRG----
                                           :.*. .   *  : :       :    * *:    .  *    

Mb3483|M.bovis_AF2122/97            LLAAGLSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRR
Rv3454|M.tuberculosis_H37Rv         LLAAGLSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRR
MMAR_1096|M.marinum_M               LLAAGLSIVAFFGGLGETLRPYSPLVAISVALVMPPILAIATKGKYYLRR
MAB_2635c|M.abscessus_ATCC_199      LLSAGISILVFFGVFGATIRPYSPIVAVVIAFVLPPILALVTRGRYYLRR
MSMEG_5653|M.smegmatis_MC2_155      LAAYAIGIIAMIP-FVVTVWYTGPVANALGGVDVALFVGLFASAVAYLLM
                                    * : .:.*:.::  :  ::   .*:.    .. :. ::.  : .  **  

Mb3483|M.bovis_AF2122/97            THDGIDLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQTHG-----AHV
Rv3454|M.tuberculosis_H37Rv         THDGIDLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQTHG-----AHV
MMAR_1096|M.marinum_M               THDGIELPMYDEHGNPSAEHLNCHVCRQNFERPDMAACQTHD-----AHV
MAB_2635c|M.abscessus_ATCC_199      SDDGIDLPMYDEYGNPSGELLHCAVSGIEFERPDMLASAKPGPNGEVQYV
MSMEG_5653|M.smegmatis_MC2_155      AR---SLDLAAEQAKAQSDAREHGFEAVSFASPRTG-------------A
                                    :    .* :  * .:...      .   .*  *                .

Mb3483|M.bovis_AF2122/97            CSLCLSTDKQAEHVLPGLARAHIPGDQVP
Rv3454|M.tuberculosis_H37Rv         CSLCLSTDKQAEHVLPGLARAHIPGDQVP
MMAR_1096|M.marinum_M               CSLCLSTDKQAEHVLS----AHP------
MAB_2635c|M.abscessus_ATCC_199      SSLSLATDRIGEHVLP----ADPPRP---
MSMEG_5653|M.smegmatis_MC2_155      GTASLTDGGQSS-----------------
                                     : .*: .  ..