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MTAPVAVVTGAASGIGAAVVDALRARGYRVGVLDMAGRADADHVVAVDVSDGSAVAGAVGEIRRTLGPVS ALVTSAGHYEMAAVADIGTQAWQRMLRVHLGGLFNAARACLPDMLEARSGAVVAVASELAVGGGDCEAHY AAAKGAIIGLVRSLAAEVADRGVRVNAVAPGPTDTPLLAQDSPWRAPEYLQTLPLRRLASPREVARCVEY LVCDATFATGDVVNVNSGAVI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1070 | - | - | 100% (231) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_4376 | - | 3e-57 | 51.32% (228) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | 1e-39 | 39.75% (244) | 3-oxoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 3e-29 | 36.55% (238) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0799 | - | 4e-91 | 76.75% (228) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 3e-29 | 36.55% (238) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-29 | 34.67% (225) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0296 | - | 6e-28 | 34.94% (249) | putative 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase |
| M. marinum M | MMAR_4715 | - | 2e-36 | 39.04% (228) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 1e-39 | 40.79% (228) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. thermoresistible (build 8) | TH_3102 | - | 8e-37 | 38.60% (228) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 2e-35 | 38.16% (228) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_0044 | - | 4e-92 | 76.32% (228) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2882c|M.bovis_AF2122/97 -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
MAB_0296|M.abscessus_ATCC_1997 ---------------------MVAVVTGAGGGVGSRVVTTLARRHERVVA
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104 ----------MK----------TAVVTGGGSGIGLAVVERLRADGLNVAS
TH_3102|M.thermoresistible__bu ----------LK----------NAVVTGGGSGIGQAVAARLRADGYHVAT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mflv_0799|M.gilvum_PYR-GCK -----------MSRRSPMTDRPVALVTGGASGIGAAVADALTARGYAVGC
Mvan_0044|M.vanbaalenii_PYR-1 -----------------MTDQPVALVTGGASGIGAAVVEALTARGYTVGC
MSMEG_1070|M.smegmatis_MC2_155 -----------------MT-APVAVVTGAASGIGAAVVDALRARGYRVGV
::**. *:* : :
Mb2882c|M.bovis_AF2122/97 GDVDVEAGG-----AAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv GDVDVEAGG-----AAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRID
MAB_0296|M.abscessus_ATCC_1997 VDIDEVAIKQLVEYAADEGLDVIGQILDITDDTAVAVGVSDIESRVGPIT
MMAR_4715|M.marinum_M LDLK--TPDGE-----------LAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99 LDLK--TPDGG-----------LAFSADVTNRSQVDAALAAIRQRLGPVT
MAV_0942|M.avium_104 IDLR--PSDAE-----------LAFTADVTDRSQVDAALSAIRAQLGPVT
TH_3102|M.thermoresistible__bu IDLK--PGDDE-----------FSHAADVTDRAQVDAAFDAIRTQLGPVT
MLBr_01807|M.leprae_Br4923 THRASVVPDWF-----------FGVECDVTDNDAIGAAFKAVEEHQGPVE
Mflv_0799|M.gilvum_PYR-GCK VDLH-PGAAEN------------TVAADVSDADAVSRAVSELRDRLGPVS
Mvan_0044|M.vanbaalenii_PYR-1 LDLN-PGPAEN------------TWAVDVSDADAVARAVGQLQDRLGPVS
MSMEG_1070|M.smegmatis_MC2_155 LDMAGRADADH------------VVAVDVSDGSAVAGAVGEIRRTLGPVS
. *: : : . * :
Mb2882c|M.bovis_AF2122/97 IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
Rv2857c|M.tuberculosis_H37Rv IAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAG
MAB_0296|M.abscessus_ATCC_1997 ALVNGAGVLRTG--AAVEFSDADWARTFDVNVRAPFVLSREVARRMIPRR
MMAR_4715|M.marinum_M ILVNAAGLDGFK--RFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFK--RFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MAV_0942|M.avium_104 VLVNAAGLDGFK--KFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAG
TH_3102|M.thermoresistible__bu ILVNAAGLDLFR--RFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDM--LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
Mflv_0799|M.gilvum_PYR-GCK AVVTSAGYYEMA--PVSEIGEDAWRRMLRVHLGGLVNIARATLPDLTATG
Mvan_0044|M.vanbaalenii_PYR-1 AVVTSAGYYEMA--PVSDISEDAWRRMLRVHLGGLVNVARATLPDLTATR
MSMEG_1070|M.smegmatis_MC2_155 ALVTSAGHYEMA--AVADIGTQAWQRMLRVHLGGLFNAARACLPDMLEAR
. ** : : *:: . : :
Mb2882c|M.bovis_AF2122/97 KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
Rv2857c|M.tuberculosis_H37Rv KGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNA
MAB_0296|M.abscessus_ATCC_1997 AGSVVTVASNAALVARKG-MTAYAASKAAANAFTKSLGLELAEYGIRCNV
MMAR_4715|M.marinum_M WGRIVNISSSSTHSGTPY-MTHYVAAKSAVNGLTKALALEYGPSGITVNA
MUL_0315|M.ulcerans_Agy99 WGRIVNISSSSTHSGTPY-MTHYVAAKSAVNGLTKALALEYGPSGITVNA
MAV_0942|M.avium_104 WGRIVNISSSSTHSGAPY-MSHYVAAKSAVNGLTKSLALEYGPKGITVNA
TH_3102|M.thermoresistible__bu WGRIVNISSSSTHSGAPY-MAPYVAAKSGVNGLTKTLALEYGPAGITVNA
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPG-QANYAASKSGLIGMARSLARELGSRSITANV
Mflv_0799|M.gilvum_PYR-GCK -GSLVAVASELAVGGGDE-DAHYAAAKGAILGLVRSLAAETAGSGVRVNA
Mvan_0044|M.vanbaalenii_PYR-1 -GSLVAVASELAVGGGDE-DAHYAAAKGAILGLVRSLAVETASSGVRVNA
MSMEG_1070|M.smegmatis_MC2_155 SGAVVAVASELAVGGGDC-EAHYAAAKGAIIGLVRSLAAEVADRGVRVNA
* : .* . *.*:*.. .: : *. : . .: *.
Mb2882c|M.bovis_AF2122/97 LCPGPVNTPLLQELFAKNPER------AARRMVHVPLGRFAEPDEIAAAV
Rv2857c|M.tuberculosis_H37Rv LCPGPVNTPLLQELFAKNPER------AARRMVHVPLGRFAEPDEIAAAV
MAB_0296|M.abscessus_ATCC_1997 VAPGSTDTPMLRAMLGDSSDAGLVAGSLGDYKPGIPLGRVAQPQHIADAV
MMAR_4715|M.marinum_M VPPGFIDTPMLRNAAAQGHLG-----DIEQNIARTPVRRIGKPEDIAAAC
MUL_0315|M.ulcerans_Agy99 VPPGFIDTPMLRNAAAQGHLG-----DIEQNIARTPVRRIGKPEDIAAAC
MAV_0942|M.avium_104 VPPGFIDTPMLRAAEKNGFLG-----DIEETIARTPVRRMGTPQDIAAAC
TH_3102|M.thermoresistible__bu VPPGFIDTPMLRAAAAKGYLG-----DIDKTIEATPVRRMGKPEDIAAAC
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDSK---------YQEAALQAIPLGRIGAVEEIAGAV
Mflv_0799|M.gilvum_PYR-GCK VAPGPTDTPLLALDSPWR---------APEYLQTLPLRRLTRPAEVARSV
Mvan_0044|M.vanbaalenii_PYR-1 VAPGPTDTPLLAPDSPWR---------APEYLQTLPLRRLTTPAEVARCV
MSMEG_1070|M.smegmatis_MC2_155 VAPGPTDTPLLAQDSPWR---------APEYLQTLPLRRLASPREVARCV
: ** :* : *: *. .:* .
Mb2882c|M.bovis_AF2122/97 AFLASDDASFITASTFLVDGGISSAYVTPL
Rv2857c|M.tuberculosis_H37Rv AFLASDDASFITASTFLVDGGISSAYVTPL
MAB_0296|M.abscessus_ATCC_1997 AFLLSDQAAHITMHTLVVDGGATLGV----
MMAR_4715|M.marinum_M AFLVSEEAGYITGQILGVNGGRNT------
MUL_0315|M.ulcerans_Agy99 AFLVSEEAGYITGQILGVNGGRNT------
MAV_0942|M.avium_104 AFLVSEEAGYITGQILGVNGGRNT------
TH_3102|M.thermoresistible__bu AFLISEEAGYITGQILGVNGGRNT------
MLBr_01807|M.leprae_Br4923 SFLASEDAGYISGAVIPVDGGLGMGH----
Mflv_0799|M.gilvum_PYR-GCK EYLVCDAT-FSTGDVVNVNSGAVI------
Mvan_0044|M.vanbaalenii_PYR-1 EYLVCDAT-FSTGDVVNVNSGAVI------
MSMEG_1070|M.smegmatis_MC2_155 EYLVCDAT-FATGDVVNVNSGAVI------
:* .: : . : . *:.*