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MTDQPVALVTGGASGIGAAVVEALTARGYTVGCLDLNPGPAENTWAVDVSDADAVARAVGQLQDRLGPVS AVVTSAGYYEMAPVSDISEDAWRRMLRVHLGGLVNVARATLPDLTATRGSLVAVASELAVGGGDEDAHYA AAKGAILGLVRSLAVETASSGVRVNAVAPGPTDTPLLAPDSPWRAPEYLQTLPLRRLTTPAEVARCVEYL VCDATFSTGDVVNVNSGAVI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0044 | - | - | 100% (230) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 1e-36 | 37.00% (227) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 2e-33 | 36.95% (249) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 1e-27 | 33.04% (224) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_0799 | - | 1e-115 | 90.43% (230) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 1e-27 | 33.04% (224) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-25 | 33.33% (225) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 3e-23 | 30.36% (224) | 3-oxoacyl- |
| M. marinum M | MMAR_4715 | - | 3e-34 | 37.00% (227) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 5e-37 | 38.33% (227) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_1070 | - | 4e-92 | 76.32% (228) | 3-oxoacyl- |
| M. thermoresistible (build 8) | TH_3102 | - | 2e-34 | 37.44% (227) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 1e-33 | 36.12% (227) | 3-oxoacyl- |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0044|M.vanbaalenii_PYR-1 ------MTD-----------------QPVALVTGGASGIGAAVVEALTAR
Mflv_0799|M.gilvum_PYR-GCK MSRRSPMTD-----------------RPVALVTGGASGIGAAVADALTAR
MSMEG_1070|M.smegmatis_MC2_155 ------MT------------------APVAVVTGAASGIGAAVVDALRAR
MMAR_4715|M.marinum_M ------MK--------------------TAVVTGGASGIGLAIARRLRAD
MUL_0315|M.ulcerans_Agy99 ------MRPDSSPS----------WCTITSVVTGGASGIGLAIARRLSAD
MAV_0942|M.avium_104 ------MK--------------------TAVVTGGGSGIGLAVVERLRAD
TH_3102|M.thermoresistible__bu ------LK--------------------NAVVTGGGSGIGQAVAARLRAD
Mb1519|M.bovis_AF2122/97 ------MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAAD
Rv1483|M.tuberculosis_H37Rv ------MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAAD
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
MAB_2723c|M.abscessus_ATCC_199 ------MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAAD
: :***. *** *:. * *
Mvan_0044|M.vanbaalenii_PYR-1 GYTVGCLDLN--PGPAENTWAVDVSDADAVARAVGQLQDRLGPVSAVVTS
Mflv_0799|M.gilvum_PYR-GCK GYAVGCVDLH--PGAAENTVAADVSDADAVSRAVSELRDRLGPVSAVVTS
MSMEG_1070|M.smegmatis_MC2_155 GYRVGVLDMAG-RADADHVVAVDVSDGSAVAGAVGEIRRTLGPVSALVTS
MMAR_4715|M.marinum_M GIDVATLDLK--TPDGELAFSADVTNRSQVDAALTAIRQRLGPVTILVNA
MUL_0315|M.ulcerans_Agy99 GTDVATLDLK--TPDGGLAFSADVTNRSQVDAALAAIRQRLGPVTILVNA
MAV_0942|M.avium_104 GLNVASIDLR--PSDAELAFTADVTDRSQVDAALSAIRAQLGPVTVLVNA
TH_3102|M.thermoresistible__bu GYHVATIDLK--PGDDEFSHAADVTDRAQVDAAFDAIRTQLGPVTILVNA
Mb1519|M.bovis_AF2122/97 GHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSN
Rv1483|M.tuberculosis_H37Rv GHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSN
MLBr_01807|M.leprae_Br4923 GHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVAN
MAB_2723c|M.abscessus_ATCC_199 GHKVAVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVAN
* *. . *::: : *. :. *** :*
Mvan_0044|M.vanbaalenii_PYR-1 AGYYEMAPVSDISEDAWRRMLRVHLGGLVNVARATLPDLTATR-GSLVAV
Mflv_0799|M.gilvum_PYR-GCK AGYYEMAPVSEIGEDAWRRMLRVHLGGLVNIARATLPDLTATG-GSLVAV
MSMEG_1070|M.smegmatis_MC2_155 AGHYEMAAVADIGTQAWQRMLRVHLGGLFNAARACLPDMLEARSGAVVAV
MMAR_4715|M.marinum_M AGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGRIVNI
MUL_0315|M.ulcerans_Agy99 AGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWGRIVNI
MAV_0942|M.avium_104 AGLDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAGWGRIVNI
TH_3102|M.thermoresistible__bu AGLDLFRRFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAGWGRIVNI
Mb1519|M.bovis_AF2122/97 AGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFI
Rv1483|M.tuberculosis_H37Rv AGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFI
MLBr_01807|M.leprae_Br4923 AGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFM
MAB_2723c|M.abscessus_ATCC_199 AGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFM
** . : : : ::: .:* * .. : .: * : :
Mvan_0044|M.vanbaalenii_PYR-1 ASELAVGGGDEDAHYAAAKGAILGLVRSLAVETASSGVRVNAVAPGPTDT
Mflv_0799|M.gilvum_PYR-GCK ASELAVGGGDEDAHYAAAKGAILGLVRSLAAETAGSGVRVNAVAPGPTDT
MSMEG_1070|M.smegmatis_MC2_155 ASELAVGGGDCEAHYAAAKGAIIGLVRSLAAEVADRGVRVNAVAPGPTDT
MMAR_4715|M.marinum_M SSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPPGFIDT
MUL_0315|M.ulcerans_Agy99 SSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPPGFIDT
MAV_0942|M.avium_104 SSSSTHSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVNAVPPGFIDT
TH_3102|M.thermoresistible__bu SSSSTHSGAPYMAPYVAAKSGVNGLTKTLALEYGPAGITVNAVPPGFIDT
Mb1519|M.bovis_AF2122/97 GSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDT
Rv1483|M.tuberculosis_H37Rv GSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDT
MLBr_01807|M.leprae_Br4923 GSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDT
MAB_2723c|M.abscessus_ATCC_199 GSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFIDT
.* * : * *:*..: *:.:::: * . .: .*.*.** **
Mvan_0044|M.vanbaalenii_PYR-1 PLLAPDSP----WRAPEYLQTLPLRRLTTPAEVARCVEYLVCDAT-FSTG
Mflv_0799|M.gilvum_PYR-GCK PLLALDSP----WRAPEYLQTLPLRRLTRPAEVARSVEYLVCDAT-FSTG
MSMEG_1070|M.smegmatis_MC2_155 PLLAQDSP----WRAPEYLQTLPLRRLASPREVARCVEYLVCDAT-FATG
MMAR_4715|M.marinum_M PMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEAGYITG
MUL_0315|M.ulcerans_Agy99 PMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEAGYITG
MAV_0942|M.avium_104 PMLRAAEKNGFLGDIEETIARTPVRRMGTPQDIAAACAFLVSEEAGYITG
TH_3102|M.thermoresistible__bu PMLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAACAFLISEEAGYITG
Mb1519|M.bovis_AF2122/97 DMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISG
Rv1483|M.tuberculosis_H37Rv DMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISG
MLBr_01807|M.leprae_Br4923 EMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISG
MAB_2723c|M.abscessus_ATCC_199 DMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSG
: : * *: ::* :* . : : :*
Mvan_0044|M.vanbaalenii_PYR-1 DVVNVNSGAVI--
Mflv_0799|M.gilvum_PYR-GCK DVVNVNSGAVI--
MSMEG_1070|M.smegmatis_MC2_155 DVVNVNSGAVI--
MMAR_4715|M.marinum_M QILGVNGGRNT--
MUL_0315|M.ulcerans_Agy99 QILGVNGGRNT--
MAV_0942|M.avium_104 QILGVNGGRNT--
TH_3102|M.thermoresistible__bu QILGVNGGRNT--
Mb1519|M.bovis_AF2122/97 AVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv AVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923 AVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199 AVIPVDGGLGMGH
:: *:.*