For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
STLTDKPVVVITGAGSGIGAAIAALLRERGWAVASISREPAPDNDLWLIADVADEREVTDAVVTVRDTLG RIDAAVVCAGHYQETPALDIDQPSWERMLRVHVGGLAHVCRAVLPDMREQGRGRIVGIASERAIGGGSND AHYAAAKAAALSLLRSIAVEVAPDGIIVNAVAPGPCDTPLLPPDSWERAEEFVQTLPAGRIALPTEVAEM VRALLEEDMNLCGEVLSVNSGTVI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4376 | - | - | 100% (235) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_1070 | - | 4e-57 | 51.32% (228) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_4800 | - | 2e-33 | 39.21% (227) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 8e-23 | 35.71% (224) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0799 | - | 6e-58 | 50.00% (234) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 9e-23 | 35.71% (224) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 8e-21 | 28.89% (225) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 5e-22 | 28.22% (241) | short chain dehydrogenase |
| M. marinum M | MMAR_4715 | - | 1e-31 | 37.00% (227) | 3-oxoacyl- |
| M. avium 104 | MAV_0942 | - | 6e-34 | 38.77% (227) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. thermoresistible (build 8) | TH_3102 | - | 1e-33 | 37.89% (227) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 7e-31 | 36.56% (227) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_0044 | - | 3e-60 | 50.86% (232) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0799|M.gilvum_PYR-GCK -----------MSRRSPMTDRPVALVTGGASGIGAAVADALTARGYAVGC
Mvan_0044|M.vanbaalenii_PYR-1 -----------------MTDQPVALVTGGASGIGAAVVEALTARGYTVGC
MSMEG_4376|M.smegmatis_MC2_155 --------------MSTLTDKPVVVITGAGSGIGAAIAALLRERGWAVAS
Mb2882c|M.bovis_AF2122/97 -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104 ----------MK----------TAVVTGGGSGIGLAVVERLRADGLNVAS
TH_3102|M.thermoresistible__bu ----------LK----------NAVVTGGGSGIGQAVAARLRADGYHVAT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAV
::**. *** . : * :
Mflv_0799|M.gilvum_PYR-GCK VDLHPGAA-------------ENTVA-ADVSDADAVSRAVSELRDRLGPV
Mvan_0044|M.vanbaalenii_PYR-1 LDLNPGPA-------------ENTWA-VDVSDADAVARAVGQLQDRLGPV
MSMEG_4376|M.smegmatis_MC2_155 ISREPAPD-------------NDLWLIADVADEREVTDAVVTVRDTLGRI
Mb2882c|M.bovis_AF2122/97 GDVDVEAGGAA------ADELSGLFVPTDVCDEDAVNGLFDGAAETYGRI
Rv2857c|M.tuberculosis_H37Rv GDVDVEAGGAA------ADELSGLFVPTDVCDEDAVNGLFDGAAETYGRI
MMAR_4715|M.marinum_M LDLKTPDG--------------ELAFSADVTNRSQVDAALTAIRQRLGPV
MUL_0315|M.ulcerans_Agy99 LDLKTPDG--------------GLAFSADVTNRSQVDAALAAIRQRLGPV
MAV_0942|M.avium_104 IDLRPSDA--------------ELAFTADVTDRSQVDAALSAIRAQLGPV
TH_3102|M.thermoresistible__bu IDLKPGDD--------------EFSHAADVTDRAQVDAAFDAIRTQLGPV
MLBr_01807|M.leprae_Br4923 THRAS------------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
** : * :
Mflv_0799|M.gilvum_PYR-GCK SAVVTSAGYY--EMAPVSEIGEDAWRRMLRVHLGGLVNIARATLPDLTAT
Mvan_0044|M.vanbaalenii_PYR-1 SAVVTSAGYY--EMAPVSDISEDAWRRMLRVHLGGLVNVARATLPDLTAT
MSMEG_4376|M.smegmatis_MC2_155 DAAVVCAGHY--QETPALDIDQPSWERMLRVHVGGLAHVCRAVLPDMREQ
Mb2882c|M.bovis_AF2122/97 DIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLA
Rv2857c|M.tuberculosis_H37Rv DIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLA
MMAR_4715|M.marinum_M TILVNAAGLD--GFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAA
MUL_0315|M.ulcerans_Agy99 TILVNAAGLD--GFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAA
MAV_0942|M.avium_104 TVLVNAAGLD--GFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEA
TH_3102|M.thermoresistible__bu TILVNAAGLD--LFRRFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEA
MLBr_01807|M.leprae_Br4923 EVLVANAGIT--SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIF--PEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTAS
** .: *:: . : :
Mflv_0799|M.gilvum_PYR-GCK G-GSLVAVASELAVGG-GDEDAHYAAAKGAILGLVRSLAAETAGSGVRVN
Mvan_0044|M.vanbaalenii_PYR-1 R-GSLVAVASELAVGG-GDEDAHYAAAKGAILGLVRSLAVETASSGVRVN
MSMEG_4376|M.smegmatis_MC2_155 GRGRIVGIASERAIGG-GSNDAHYAAAKAAALSLLRSIAVEVAPDGIIVN
Mb2882c|M.bovis_AF2122/97 GKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVN
Rv2857c|M.tuberculosis_H37Rv GKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVN
MMAR_4715|M.marinum_M GWGRIVNISSSSTHSG-TPYMTHYVAAKSAVNGLTKALALEYGPSGITVN
MUL_0315|M.ulcerans_Agy99 GWGRIVNISSSSTHSG-TPYMTHYVAAKSAVNGLTKALALEYGPSGITVN
MAV_0942|M.avium_104 GWGRIVNISSSSTHSG-APYMSHYVAAKSAVNGLTKSLALEYGPKGITVN
TH_3102|M.thermoresistible__bu GWGRIVNISSSSTHSG-APYMAPYVAAKSGVNGLTKTLALEYGPAGITVN
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
MAB_0952|M.abscessus_ATCC_1997 GRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVN
* : .* * *:*.. .: : . : . .: .*
Mflv_0799|M.gilvum_PYR-GCK AVAPGPTDTPLLAL----DSPWRAPEYLQTLPLRRLTRPAEVARSVEYLV
Mvan_0044|M.vanbaalenii_PYR-1 AVAPGPTDTPLLAP----DSPWRAPEYLQTLPLRRLTTPAEVARCVEYLV
MSMEG_4376|M.smegmatis_MC2_155 AVAPGPCDTPLLPP----DSWERAEEFVQTLPAGRIALPTEVAEMVRALL
Mb2882c|M.bovis_AF2122/97 ALCPGPVNTPLLQELFA-KNPERAARRMVHVPLGRFAEPDEIAAAVAFLA
Rv2857c|M.tuberculosis_H37Rv ALCPGPVNTPLLQELFA-KNPERAARRMVHVPLGRFAEPDEIAAAVAFLA
MMAR_4715|M.marinum_M AVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLV
MUL_0315|M.ulcerans_Agy99 AVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLV
MAV_0942|M.avium_104 AVPPGFIDTPMLRAAEKNGFLGDIEETIARTPVRRMGTPQDIAAACAFLV
TH_3102|M.thermoresistible__bu AVPPGFIDTPMLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAACAFLI
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRA----MDSKYQEAALQAIPLGRIGAVEEIAGAVSFLA
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVD----MGEEYISGMARSIPMGMLGSPVDIGHLAAFLA
.: ** * * : ::. *
Mflv_0799|M.gilvum_PYR-GCK CDAT-FSTGDVVNVNSGAVI---------
Mvan_0044|M.vanbaalenii_PYR-1 CDAT-FSTGDVVNVNSGAVI---------
MSMEG_4376|M.smegmatis_MC2_155 EEDM-NLCGEVLSVNSGTVI---------
Mb2882c|M.bovis_AF2122/97 SDDA-SFITASTFLVDGGISSAYVTPL--
Rv2857c|M.tuberculosis_H37Rv SDDA-SFITASTFLVDGGISSAYVTPL--
MMAR_4715|M.marinum_M SEEAGYITGQILGVNGGRNT---------
MUL_0315|M.ulcerans_Agy99 SEEAGYITGQILGVNGGRNT---------
MAV_0942|M.avium_104 SEEAGYITGQILGVNGGRNT---------
TH_3102|M.thermoresistible__bu SEEAGYITGQILGVNGGRNT---------
MLBr_01807|M.leprae_Br4923 SEDAGYISGAVIPVDGGLGMGH-------
MAB_0952|M.abscessus_ATCC_1997 TDEAGYITGQAIVVDGGQVLPESPDAVNP
: : .*