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MRALLSREVGDAIRDYIVEHGLKPGDALPSEGELATLLDVGKTSVREALRRLEAHGVVEVRRGRGLFVGT FSFGPLIEHLPYGLQADNVPLRQLLQARRALEEGLVCEVARVITAEDLDRLDALVEQMRAHTVDGRVPAE VDQAFHQALFAPLGNPFVLQLIDVFWSIFRRASDRIVLDLRRPTAEDHAAIVDALRSGDRAAMTDAVARH FEDLQRSLDAEVNSPLAGEANEAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0874 | - | - | 100% (234) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5375 | - | 8e-23 | 32.70% (211) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2173 | - | 8e-17 | 30.69% (202) | GntR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 6e-10 | 39.60% (101) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2114 | - | 1e-13 | 29.20% (226) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0586 | - | 6e-10 | 39.60% (101) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0068 | - | 1e-12 | 30.73% (218) | GntR family transcriptional regulator |
| M. marinum M | MMAR_3975 | - | 5e-13 | 27.75% (227) | FadR family transcriptional regulator |
| M. avium 104 | MAV_2542 | - | 1e-13 | 30.45% (220) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4115 | - | 4e-13 | 28.77% (219) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3832 | - | 4e-13 | 27.75% (227) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4590 | - | 9e-13 | 29.09% (220) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2114|M.gilvum_PYR-GCK MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mvan_4590|M.vanbaalenii_PYR-1 MTRNTPLAPMIGPDAVASRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAV_2542|M.avium_104 MPKREPLAPMA---TSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFL
MMAR_3975|M.marinum_M MTALG--------IGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99 MTALG--------IGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
Mb0601|M.bovis_AF2122/97 ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
Rv0586|M.tuberculosis_H37Rv ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
TH_4115|M.thermoresistible__bu -----------------------VQSSYIQVADQLRDLILRGDLAVGQKL
MSMEG_0874|M.smegmatis_MC2_155 ----------------------MRALLSREVGDAIRDYIVEHGLKPGDAL
MAB_0068|M.abscessus_ATCC_1997 ------------------MIRTVAISASEEAYRSVKESILNGDIPGGELL
. : :: : *: *
Mflv_2114|M.gilvum_PYR-GCK PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGAR--VRVPG--
Mvan_4590|M.vanbaalenii_PYR-1 PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGAR--VRVPG--
MAV_2542|M.avium_104 PYEAELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGAR--VRVPG--
MMAR_3975|M.marinum_M PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAV--VHAPA--
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAV--VHAPA--
Mb0601|M.bovis_AF2122/97 PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAG--
Rv0586|M.tuberculosis_H37Rv PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAG--
TH_4115|M.thermoresistible__bu PSEAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERL
MSMEG_0874|M.smegmatis_MC2_155 PSEGELATLLDVGKTSVREALRRLEAHGVVEVRRG--RGLFVGTFSFG--
MAB_0068|M.abscessus_ATCC_1997 S-EGEISARMGCSRTPVREAFLRLETEGWLR-------------------
. : : : . .:***. * : :
Mflv_2114|M.gilvum_PYR-GCK PEIVARPAGLLLELSGATIADLLTAKSAIEPMAARLLAE--SGSAAAFDE
Mvan_4590|M.vanbaalenii_PYR-1 PEIVARPAGLLLELSGATIADLLTAKSGIEPMAARLLAE--SGSPEAFDE
MAV_2542|M.avium_104 PEIVARPAGFLLEMAGTTLADVMTARMGIEPYAARLLAE--DGTAAAHRE
MMAR_3975|M.marinum_M KTSAAYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPE
MUL_3832|M.ulcerans_Agy99 KASAAYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPE
Mb0601|M.bovis_AF2122/97 LDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAE---RNEPELAE
Rv0586|M.tuberculosis_H37Rv LDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAE---RNEPELAE
TH_4115|M.thermoresistible__bu EGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAALAAA--ARGGDQVEE
MSMEG_0874|M.smegmatis_MC2_155 --PLIEHLPYGLQADNVPLRQLLQARRALEEGLVCEVAR--VITAEDLDR
MAB_0068|M.abscessus_ATCC_1997 --LYPKRGALVVPITPEERRHVVDARRVIEGAAAARIAER-GAPQSLLSD
. * . *
Mflv_2114|M.gilvum_PYR-GCK LEQLLEELVADSHQSPRL--AEATGAFHLRVVQLSGNATLSIVAGMLHEI
Mvan_4590|M.vanbaalenii_PYR-1 LERMLEELAADSHKSSRL--AEATGLFHLRVVQLSGNATLSIVAGMLHEI
MAV_2542|M.avium_104 LRELIEEIPA-AWETGKL--GAASTALHRRLVELSGNATLTVIVGMLHEI
MMAR_3975|M.marinum_M LKRVNEAMSEHLDDGAMF--TEIGRQFHDLIVRGCGNHTIIAVVGSLETL
MUL_3832|M.ulcerans_Agy99 LKRVNEAMSEHLDDGAMF--TEIGRQFHDLIVRGCGNHTIIAVVGSLETL
Mb0601|M.bovis_AF2122/97 LLQDSLRALDTEEDPIVW--QRHTLDFWDHVVDSAGSIVDRLMYNAFRAA
Rv0586|M.tuberculosis_H37Rv LLQDSLRALDTEEDPIVW--QRHTLDFWDHVVDSAGSIVDRLMYNAFRAA
TH_4115|M.thermoresistible__bu LKRTAAMVDPADQEAA----MQQSADFHSAILRASGNKLLEAMGRPVSAV
MSMEG_0874|M.smegmatis_MC2_155 LDALVEQMRAHTVDGRVP--AEVDQAFHQALFAPLGNPFVLQLIDVFWSI
MAB_0068|M.abscessus_ATCC_1997 LSALIEVQLGRAAQGDAAGFAAADVDFHRAIVAKLGNPLLENFYDSLRER
* . : :. *. . .
Mflv_2114|M.gilvum_PYR-GCK TVRHTAFVFNERR----PVSKADYETLLRSYRRLLQFLRSRDADGAEAHW
Mvan_4590|M.vanbaalenii_PYR-1 TVRHTAFVFNERR----PVSKADYDTLLRSYRKLMQFLRAGDAVGAEAHW
MAV_2542|M.avium_104 FERHMTAAFLSVQN---VVPKAQYNKLMRSYTRLADLVAARDGAEAEAHW
MMAR_3975|M.marinum_M WTSHEQQWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIA
MUL_3832|M.ulcerans_Agy99 WTSHEQQWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIA
Mb0601|M.bovis_AF2122/97 YEPTLAALT---------TTMTAAAKRPSDYRKLADAICSGDPTGAKKAA
Rv0586|M.tuberculosis_H37Rv YEPTLAALT---------TTMTAAAKRPSDYRKLADAICSGDPTGAKKAA
TH_4115|M.thermoresistible__bu ARSKFRRTVP---------GLEFWERNQRAHQELLKAILAGDENLAYELA
MSMEG_0874|M.smegmatis_MC2_155 FRRASDRIV-----------LDLRRPTAEDHAAIVDALRSGDRAAMTDAV
MAB_0068|M.abscessus_ATCC_1997 QRRMAAAAIG--------VDPVRVARSVAGHRALVDALAAGDAARFSTEL
: : . : *
Mflv_2114|M.gilvum_PYR-GCK RRHLDKTRELLLAGLESVPVRDVMG------------
Mvan_4590|M.vanbaalenii_PYR-1 RKHLDTTRELLLTGLESVPVRDVMG------------
MAV_2542|M.avium_104 RRHMENASAELLKGHEKTKVRDIMH------------
MMAR_3975|M.marinum_M GRHLADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP
MUL_3832|M.ulcerans_Agy99 GRHLADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP
Mb0601|M.bovis_AF2122/97 QDLLELANTSLMAVLVSQASRQ---------------
Rv0586|M.tuberculosis_H37Rv QDLLELANTSLMAVLVSQASRQ---------------
TH_4115|M.thermoresistible__bu TRHIDEDLSPYYLPPEEADRDGAGA------------
MSMEG_0874|M.smegmatis_MC2_155 ARHFEDLQRSLDAEVNSPLAGEANEAS----------
MAB_0068|M.abscessus_ATCC_1997 VEHMKVVTEVD--------------------------
: