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SDETKVTVERTITAPVDAIFDVLSNPERHQELDGSGFVRSVDHADRIQKVGEVFTMNMQGDHMGGEYKTD NHVTGYAKDKLLAWQTAPAGTEPPGWEWLWELESQGPGETLVRHTYDWSKVTDKKLLEKVKFPLVSKDQL SDTLARLAAAVSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3232 | - | - | 100% (154) | hypothetical protein Mflv_3232 |
| M. gilvum PYR-GCK | Mflv_0146 | - | 1e-21 | 35.57% (149) | hypothetical protein Mflv_0146 |
| M. gilvum PYR-GCK | Mflv_2610 | - | 2e-16 | 33.10% (145) | hypothetical protein Mflv_2610 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0091 | - | 6e-12 | 30.50% (141) | hypothetical protein Mb0091 |
| M. tuberculosis H37Rv | Rv0088 | - | 6e-12 | 30.50% (141) | hypothetical protein Rv0088 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2457c | - | 3e-19 | 32.26% (155) | hypothetical protein MAB_2457c |
| M. marinum M | MMAR_0253 | - | 2e-17 | 30.82% (146) | hypothetical protein MMAR_0253 |
| M. avium 104 | MAV_5230 | - | 4e-20 | 32.48% (157) | hypothetical protein MAV_5230 |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 7e-25 | 38.16% (152) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4053 | - | 3e-15 | 30.49% (164) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4861 | - | 1e-17 | 30.82% (146) | hypothetical protein MUL_4861 |
| M. vanbaalenii PYR-1 | Mvan_0758 | - | 8e-20 | 36.49% (148) | hypothetical protein Mvan_0758 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
MAV_5230|M.avium_104 --------------------------------------------------
MAB_2457c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 MAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVGTLYHRFGN
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
MAV_5230|M.avium_104 --------------------------------------------------
MAB_2457c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RDGILKATWLRGIERFQRRAMAADGATPVDVAVAMAGAVLQFARDEPEDA
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
MAV_5230|M.avium_104 --------------------------------------------------
MAB_2457c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RLLLSIRRADLLDGGPDADFDATLADMNAPVFERLHELARGIFGRDDDRA
Mb0091|M.bovis_AF2122/97 ---------------------MSVYKHAPSRVRLRQTRSTVVKGRSGSLS
Rv0088|M.tuberculosis_H37Rv ---------------------MSVYKHAPSRVRLRQTRSTVVKGRSGSLS
TH_4053|M.thermoresistible__bu ---------------------------------MS-----DIQTTGTSLA
Mvan_0758|M.vanbaalenii_PYR-1 ---------------------------------MSPACDRGLTRMTETLI
Mflv_3232|M.gilvum_PYR-GCK ------------------------------------------MSDETKVT
MMAR_0253|M.marinum_M ------------------------------MVDTDAPLPD---RSERVVS
MUL_4861|M.ulcerans_Agy99 ------------------------------MVDTDAPLPD---RSERVVS
MAV_5230|M.avium_104 ------------------------------MSDTEA---------ERIVS
MAB_2457c|M.abscessus_ATCC_199 ------------------------------MTDDVR-----------VVS
MSMEG_0859|M.smegmatis_MC2_155 MDAVMRAVADLPYATVRRHIDDGKW--PVWLSEDLATSVRRLLSVDKIVS
Mb0091|M.bovis_AF2122/97 WRRVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVS
Rv0088|M.tuberculosis_H37Rv WRRVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVS
:
TH_4053|M.thermoresistible__bu VHTTVNAPARTVFDVLADPTTHARIDGTGWVREPVDGARLTGAGQIFRMG
Mvan_0758|M.vanbaalenii_PYR-1 VDTIVDAPASTVFAVLADPATHAAIDGTGWVRESLDGEPITRSGQMFRMA
Mflv_3232|M.gilvum_PYR-GCK VERTITAPVDAIFDVLSNPERHQELDGSGFVRSVDHADRIQKVGEVFTMN
MMAR_0253|M.marinum_M ATREIAAGAAQIFELIADPSRQPDWDGNDNLAHCAAGQRVHRVGDVFRMT
MUL_4861|M.ulcerans_Agy99 ATREIAAGAAQIFELIADPSRQPDWDGNDNLAHCAAGQRVHRVGDVFRMT
MAV_5230|M.avium_104 ATRVIAANAARIFELIADPARQPGWDGNDNLASAAPGQRVHRVGDVFKMT
MAB_2457c|M.abscessus_ATCC_199 ASREVQASAAAIFELIADPARQREWDGNENLAEAAAGQRAHAVGDVFVMT
MSMEG_0859|M.smegmatis_MC2_155 ASREIAAPSDVIFELIADPAQQPRWDGNENLLRMASGGRVRGVGEVFTME
Mb0091|M.bovis_AF2122/97 RSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKLVVGSKFSTK
Rv0088|M.tuberculosis_H37Rv RSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKLVVGSKFSTK
: * :* ::::* : **. : *. *
TH_4053|M.thermoresistible__bu MYHEN--HPHRHYEIANRVEVFDPPHAIAWQPGAEPRHIPGRGADATGPV
Mvan_0758|M.vanbaalenii_PYR-1 MYFANPAFADGHYEVANKVIAFEPDRAIGWEPG---------QAREDGTV
Mflv_3232|M.gilvum_PYR-GCK MQGDH---MGGEYKTDNHVTGYAKDKLLAWQTAP-------------AGT
MMAR_0253|M.marinum_M LTLGS--------VRENHIVEFTEARLIAWRPSE-------------LGK
MUL_4861|M.ulcerans_Agy99 LTLGS--------VRENHIVEFTEARLIAWRPSE-------------LGK
MAV_5230|M.avium_104 LTNGA--------VRENHVTEFVEGSVIAWRPAE-------------PGK
MAB_2457c|M.abscessus_ATCC_199 LTTGA--------DRENHIVEFEEARRIAWLPSE-------------VGK
MSMEG_0859|M.smegmatis_MC2_155 IKQGG--------FRDNHVIEFEEGRRIAWRPAV-------------AGE
Mb0091|M.bovis_AF2122/97 MKLFG-----LPYRITSRVTALKPNELVEWSHPL----------------
Rv0088|M.tuberculosis_H37Rv MKLFG-----LPYRITSRVTALKPNELVEWSHPL----------------
: .:: : *
TH_4053|M.thermoresistible__bu EFGGWIWRYDLAPQHAPGAPAGTRVTLTYDWSQVP-A----ADRRAMRFP
Mvan_0758|M.vanbaalenii_PYR-1 EHGGWTWRYDLEAVG----PGLTRVTLTYDWSAVP-A----TLREHIAFP
Mflv_3232|M.gilvum_PYR-GCK EPPGWEWLWELESQG----PGETLVRHTYDWSKVTDK----KLLEKVKFP
MMAR_0253|M.marinum_M TPPGHLWRWELTPIS----GTRTLVTHTYDWTELS------DPARFPRAR
MUL_4861|M.ulcerans_Agy99 TPPGHLWRWELTPIS----GTRTLVTHTYDWTELS------DPARFPRAR
MAV_5230|M.avium_104 QPPGHLWRWELSPVN----AELTTVTHTYDWTALT------DPTRLQRAR
MAB_2457c|M.abscessus_ATCC_199 RPPGHLWRWELRPLD----DDRTQVTHTYDWTNLT------DEKRLVRAR
MSMEG_0859|M.smegmatis_MC2_155 QPLGHLWRWELQPAG----EGRTLVTHTYDWTQLT------DEKRFPKAS
Mb0091|M.bovis_AF2122/97 ---GHRWRWEFESLS----PTLTRVTETFDYHAAGAIKNGLKFYEMTGFA
Rv0088|M.tuberculosis_H37Rv ---GHRWRWEFESLS----PTLTRVTETFDYHAAGAIKNGLKFYEMTGFA
* * ::: . * * *:*: .
TH_4053|M.thermoresistible__bu PFPPEHLVNSLRHLK---ELAERDVPR
Mvan_0758|M.vanbaalenii_PYR-1 PFPVDHLHNSLANLA---KLAAG----
Mflv_3232|M.gilvum_PYR-GCK LVSKDQLSDTLARLA---AAVSS----
MMAR_0253|M.marinum_M ATTTVQLRASLDRLAGHAEAAAAGD--
MUL_4861|M.ulcerans_Agy99 ATTTVQLRASLDRLAGHAEAAAAGD--
MAV_5230|M.avium_104 ATTPEMLRESMDRLA---TLAQSGD--
MAB_2457c|M.abscessus_ATCC_199 NTTSERLQASVDRLA---ALAESGA--
MSMEG_0859|M.smegmatis_MC2_155 ATTADKLQESVDRLA---AIVEG----
Mb0091|M.bovis_AF2122/97 KSNAAGIEATLAKLS--DQYARGRA--
Rv0088|M.tuberculosis_H37Rv KSNAAGIEATLAKLS--DQYARGRA--
: :: .* .