For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SKKFESNRDEILRISAELFAKSGYHGTGISDLGAAVGLGRGALYHYIGSKETILYEISSRQLAQMNNLAD ELALTEKDPEKRLRGLARALLRNIAEHRAEWTVFFREYHALTGERRDRVIAARERYEAHWRNALDQGVRD GQFRPLPTLMVKGLLGMFNYSYLWLTLDGPESPEDIADEFLDTVLVGMNADGLRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0712 | - | - | 100% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0120 | - | 2e-19 | 31.77% (192) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 3e-15 | 28.49% (186) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0163 | - | 7e-19 | 31.79% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0719 | - | 1e-19 | 31.25% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0158 | - | 8e-19 | 31.79% (195) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 3e-07 | 25.00% (116) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 3e-29 | 34.41% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0381 | - | 5e-18 | 32.64% (193) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5138 | - | 1e-19 | 31.98% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0160 | - | 9e-22 | 33.67% (196) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4731 | - | 4e-18 | 32.64% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0126 | - | 3e-19 | 33.16% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0712|M.smegmatis_MC2_155 ---------------MSKKFESNRDEILRISAELFAKSGYHGTGISDLGA
MAB_4912c|M.abscessus_ATCC_199 MTEAGAKPRRGRPPASDGDAAATRQRIMEVATDLFAEKGFHATGVAEIGA
Mb0163|M.bovis_AF2122/97 ----------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVAD
Rv0158|M.tuberculosis_H37Rv ----------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVAD
MMAR_0381|M.marinum_M ----------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVAD
MUL_4731|M.ulcerans_Agy99 ----------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVAD
MAV_5138|M.avium_104 ----------MPADSSTPNGQTRREELLAVATKLFAARGYHGTRMDDVAD
Mflv_0719|M.gilvum_PYR-GCK --------------------MSRREELLAVATKLFAARGYHGTRMDDVAD
Mvan_0126|M.vanbaalenii_PYR-1 ----------MSESTT--NGMSRREELLAVATKLFAARGYHGTRMDDVAD
TH_0160|M.thermoresistible__bu --------------------MTRREELLAVATRLFAARGYHGTRMDDVAD
MLBr_02568|M.leprae_Br4923 ----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAA
.:.:: :. :*: *:* * : :.
MSMEG_0712|M.smegmatis_MC2_155 AVGLGRGALYHYIGSKETILYEISSRQLAQMNNLADELALTEKDPEKRLR
MAB_4912c|M.abscessus_ATCC_199 AAGVRGGALYYHIGSKEELLWEILRSYIDEMLTEAVHIANMNTEPARRLR
Mb0163|M.bovis_AF2122/97 VIGLNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSWTAR--EALY
Rv0158|M.tuberculosis_H37Rv VIGLNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSWTAR--EALY
MMAR_0381|M.marinum_M VIGLNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEPSWTAR--EALY
MUL_4731|M.ulcerans_Agy99 VIGLNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEPSWTAR--EALY
MAV_5138|M.avium_104 VIGLNKATVYHYYASKSLILYDIYQQAAERTLAAVHDDPSMTAR--EALY
Mflv_0719|M.gilvum_PYR-GCK AVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTASAR--ETIY
Mvan_0126|M.vanbaalenii_PYR-1 AVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTATAR--ETIY
TH_0160|M.thermoresistible__bu AIGLNKATVYHYYASKSLILYDIYRRAADSTVAALHDDPNASAR--EMIY
MLBr_02568|M.leprae_Br4923 EAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLR
: :* : .**. :: :
MSMEG_0712|M.smegmatis_MC2_155 GLARALLRNIAEHRAEWTVFFREY----HALTGERRDRVIAARERYEAHW
MAB_4912c|M.abscessus_ATCC_199 TLIGSYVILIVKYRKQVAIQVRDG----SALTGERAAQLQGLRDELQRCW
Mb0163|M.bovis_AF2122/97 QYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHV
Rv0158|M.tuberculosis_H37Rv QYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHV
MMAR_0381|M.marinum_M QYTVRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHV
MUL_4731|M.ulcerans_Agy99 QYTVRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHV
MAV_5138|M.avium_104 QYTVRLLDQIAANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQVYEHV
Mflv_0719|M.gilvum_PYR-GCK HFTRRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDYIREKEAQVYEHV
Mvan_0126|M.vanbaalenii_PYR-1 HFTRRLLVGIANDIERAAVYFQEGPYITEWFTEEQVEYIREKETQVYEHV
TH_0160|M.thermoresistible__bu EFTRRLLVGIAGDIERAAVYFQEAPYITEWFTEEQVAYIRESEAKVYEHV
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANRASWIVMYIQA-----MSLPAFAQTVREARDQITELV
: * : : : . .
MSMEG_0712|M.smegmatis_MC2_155 RNALDQGVRDGQFRPLP-TLMVKGLLGMFNYSYLWLTLDGPESPEDIADE
MAB_4912c|M.abscessus_ATCC_199 QRVFDEGHEVGTFHTAD-HVLTNAILGMLNMVAVWYRTDG-KSPAQIAKR
Mb0163|M.bovis_AF2122/97 HGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAE
Rv0158|M.tuberculosis_H37Rv HGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAE
MMAR_0381|M.marinum_M HGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAE
MUL_4731|M.ulcerans_Agy99 HGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAE
MAV_5138|M.avium_104 HGLIDRGIASGEFYECDSHVLALGYIGMTLGAYRWLRPSGRRSAKEIAAE
Mflv_0719|M.gilvum_PYR-GCK RDVIDRGIASGEFNDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVE
Mvan_0126|M.vanbaalenii_PYR-1 RDVIDRGIASGEFYDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVE
TH_0160|M.thermoresistible__bu RDVIDRGIASGEFYECDSHVLALGYIGMTLGSYRWLRPDGRRTAEEIAEE
MLBr_02568|M.leprae_Br4923 AGLMRVGTRS-SRPDHEYEIMAGALVGAGEAMATRL-TTGDIAVDEAAEL
: * ::. . :* * : : *
MSMEG_0712|M.smegmatis_MC2_155 FLDTVLVGMNADGLRS----------------------
MAB_4912c|M.abscessus_ATCC_199 IADMVLDGIHVDRPEEHAEQAPTDRK------------
Mb0163|M.bovis_AF2122/97 FSTALLRGLIRDESIRNQSPLGTRKET-----------
Rv0158|M.tuberculosis_H37Rv FSTALLRGLIRDESIRNQSPLGTRKET-----------
MMAR_0381|M.marinum_M FSTALLRGLIRDESIRNQSPLGS---------------
MUL_4731|M.ulcerans_Agy99 FSTALLRGLIRDESIRNQSPLGS---------------
MAV_5138|M.avium_104 FSTALLRGLIRDEEIRTTSPLGP---------------
Mflv_0719|M.gilvum_PYR-GCK FSSALLRGLIRDETVRATSPLGVGIDVTAKQ-------
Mvan_0126|M.vanbaalenii_PYR-1 FSTALLRGLIRDETVRTLSPLGVGIDAPVKTRILEEPS
TH_0160|M.thermoresistible__bu FSTALLRGLIRDEKIRADFPHGTGESEAEPANPAG---
MLBr_02568|M.leprae_Br4923 MINLFWHGLKGAPADRDFGPSIVAG-------------
: . *: