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M. smegmatis MC2 155 MSMEG_0480 (-)

annotation: transcriptional regulator, GntR family protein
coordinates: 557995 - 558654
length: 219

TSEPQNKSDQAFVEIERMIVLGEIAPGSLVSEKQLMELTGLGRTPVREAVQRLSRERLLEIHPNRGVLVP
PTSVEAQLKLLELRRILEPFAVRVAASRATDSQRQAARELAEDVVSGDKTVTDFSNFLRKAHALVVAATH
NEYIEVAMAPLQGLSRRFWFGHLSDPVEELRRAAQLHHDILAAIAAGNAEAANGASLALSDYLFEFAYAT
LPRHNQPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0480--100% (219)transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_3980-2e-4948.79% (207) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_6300-4e-1730.50% (200) transcriptional regulator, GntR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0505-1e-0630.53% (131) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_0016-9e-0830.77% (182) GntR domain-containing protein
M. tuberculosis H37RvRv0494-1e-0630.53% (131) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0068-3e-1530.65% (186) GntR family transcriptional regulator
M. marinum MMMAR_0749-4e-0728.65% (185) GntR family transcriptional regulator
M. avium 104MAV_0339-6e-0831.11% (135) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_3038-2e-1434.48% (145) PUTATIVE putative transcriptional regulator, GntR family
M. ulcerans Agy99MUL_1381-3e-0727.57% (185) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_3051-7e-1433.08% (133) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0505|M.bovis_AF2122/97            MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
Rv0494|M.tuberculosis_H37Rv         MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
MMAR_0749|M.marinum_M               ----------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MUL_1381|M.ulcerans_Agy99           -------------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
Mflv_0016|M.gilvum_PYR-GCK          MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNETVLVE
MSMEG_0480|M.smegmatis_MC2_155      -----------MTSEPQNKSDQAFVEIERMIVLGEIAPG-SLVSEKQLME
MAB_0068|M.abscessus_ATCC_1997      ----------MIRTVAISASEEAYRSVKESILNGDIPGG-ELLSEGEISA
TH_3038|M.thermoresistible__bu      --------MSRTVESNGDASERAYQAVLQMILDGEAPAG-SWLREQTLAE
MAV_0339|M.avium_104                ---------MAAIDISGTVRERAARELRDRILTGALPAG-SRIDLDAITA
Mvan_3051|M.vanbaalenii_PYR-1       --MAAPTEEPSRLALPATLVEVAGNRLRDAILSGELAPG-EKIIEEQLCA
                                                              :   :       *        :  

Mb0505|M.bovis_AF2122/97            RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHPAVVEALVRK
Rv0494|M.tuberculosis_H37Rv         RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHPAVVEALVRK
MMAR_0749|M.marinum_M               MTGTARNTVREAVQALVHVGILERRQGSGTYVIADVEQGS-----ALAEY
MUL_1381|M.ulcerans_Agy99           MTGTARNTVREAVQALVHVGILERRQGSGTYVIADVEQGS-----ALAEY
Mflv_0016|M.gilvum_PYR-GCK          KFGVGRNTVREAVRALAHAGILEVRQGDGTYVRATSEVSG-----ALRR-
MSMEG_0480|M.smegmatis_MC2_155      LTGLGRTPVREAVQRLSRERLLEIHPNRGVLVPPTS--------------
MAB_0068|M.abscessus_ATCC_1997      RMGCSRTPVREAFLRLETEGWLRLYPKRGALVVPIT--------------
TH_3038|M.thermoresistible__bu      QIGVSRTPVRQALNRLAAEGAIELVPNRGAQVVSFS--------------
MAV_0339|M.avium_104                EFATSRTPVREALLELSFEGLVQVAPRSGVTVIGIS--------------
Mvan_3051|M.vanbaalenii_PYR-1       DFGISRAPLREALRRLAQQGLVEHLPRRGSRVTEWS--------------
                                      .  * .:*:..  *     :.     *  *                  

Mb0505|M.bovis_AF2122/97            LGPDFLVELLEIRAALG-PLIGRLAAARSTPEDAEALCAALEVVQQ---A
Rv0494|M.tuberculosis_H37Rv         LGPDFLVELLEIRAALG-PLIGRLAAARSTPEDAEALCAALEVVQQ---A
MMAR_0749|M.marinum_M               FAAARERDLWELREAVE-VTAAVLSARRRDAADIEDLRALLARRNELWSR
MUL_1381|M.ulcerans_Agy99           FAAARERDLWELREAVE-VTAAVLSARRRDAADIEDLRVLLARRNELWSR
Mflv_0016|M.gilvum_PYR-GCK          LCGEELREVLEVRRALE-VEAARLAASRRTPADVAEMRGLLARRDE---R
MSMEG_0480|M.smegmatis_MC2_155      --VEAQLKLLELRRILE-PFAVRVAASRATDSQRQAARELAEDVVS----
MAB_0068|M.abscessus_ATCC_1997      --PEERRHVVDARRVIEGAAAARIAERGAPQSLLSDLSALIEVQLG----
TH_3038|M.thermoresistible__bu      --DEDVEALFDLRARFE-PLAVRLAVPQLTEERIAELADLATRMEA---L
MAV_0339|M.avium_104                --PEDVLDSFTILGVLT-GQAAAWAAERIGPEELATLRELAAEVVA----
Mvan_3051|M.vanbaalenii_PYR-1       --PTDILQLFELRNVLERHAIESALPLADLDRDLEPVRAALEQMDA----
                                                   .                                  

Mb0505|M.bovis_AF2122/97            DTAAARQ-----AADLAYFRVLIHSTRNRALGLLYR-WVEHAFGGREHAL
Rv0494|M.tuberculosis_H37Rv         DTAAARQ-----AADLAYFRVLIHSTRNRALGLLYR-WVEHAFGGREHAL
MMAR_0749|M.marinum_M               EPANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAVEAG-
MUL_1381|M.ulcerans_Agy99           EPANDKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAVEAG-
Mflv_0016|M.gilvum_PYR-GCK          DSAGDVE--AFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTASVAHTR
MSMEG_0480|M.smegmatis_MC2_155      ---GDKTVTDFSNFLRKAHALVVAATHNEYIEVAMAPLQGLSRRFWFGHL
MAB_0068|M.abscessus_ATCC_1997      -RAAQGDAAGFAAADVDFHRAIVAKLGNPLLENFYDSLRERQRRMAAAAI
TH_3038|M.thermoresistible__bu      LDRRPLDTHQMSRLNNAFHGIFLAEAGNRHLTAAMQAVVRPALVTLTFQK
MAV_0339|M.avium_104                ----KSGDDSIGEANWHFHQMIHRAAHSPRLANQIKHAARVVPTNFLTLF
Mvan_3051|M.vanbaalenii_PYR-1       ----SSDVLSLDDAHRAFHAAVVGLAKNRQLDIALEPILLKLQLPMARNM
                                                      .  .     .                      

Mb0505|M.bovis_AF2122/97            TGAYDDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRD
Rv0494|M.tuberculosis_H37Rv         TGAYDDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRD
MMAR_0749|M.marinum_M               --PVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRP--------
MUL_1381|M.ulcerans_Agy99           --PVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRR--------
Mflv_0016|M.gilvum_PYR-GCK          HVPVDVC-----DHGVLLDHIAAGDPDLAARTAGEFLDRIINGLGSADSS
MSMEG_0480|M.smegmatis_MC2_155      SDPVEELRRAAQLHHDILAAIAAGNAEAANGASLALSDYLFEFAYATLPR
MAB_0068|M.abscessus_ATCC_1997      GVDPVRVARSVAGHRALVDALAAGDAARFSTELVEHMKVVTEVD------
TH_3038|M.thermoresistible__bu      Y-SERALRLSMHHHAELVEAARARDPEWAEAVMRAHILAARHAGE-----
MAV_0339|M.avium_104                P---EHEKHSLDEHAQLLDALGDKDVERARAIAERHVLDAGRSLAEWLEQ
Mvan_3051|M.vanbaalenii_PYR-1       REEARQHAGPGRRHRPGAADEGIGRHKAILSALETNDPAAVVTAIRDHGH
                                                                                      

Mb0505|M.bovis_AF2122/97            RA------
Rv0494|M.tuberculosis_H37Rv         RA------
MMAR_0749|M.marinum_M               --------
MUL_1381|M.ulcerans_Agy99           --------
Mflv_0016|M.gilvum_PYR-GCK          --------
MSMEG_0480|M.smegmatis_MC2_155      HNQPA---
MAB_0068|M.abscessus_ATCC_1997      --------
TH_3038|M.thermoresistible__bu      --------
MAV_0339|M.avium_104                RRDGER--
Mvan_3051|M.vanbaalenii_PYR-1       LHYLGLAP