For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KCVLASYGTRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLTAVPYGLDSQAWLDVYRNFWTSF FRGFWKMGEMRGMWREMWDLSDQCWAQMNTTLLSLADGADLLFAGQSYQEPAANVAEYYDLPLATLHHVP MRPNGQVVSVLPAPLARSAMTAFDWFCWRLNKKVEDAQRRELGLPKATGPSPRRIAERGSLEIQAYDEVC FPGLAEEWAKWDGQRPFVGTLTMELTTEADDEVMSWIRGGTPPICFGFGSMPVESPADTVDMIGTACAQL GERALLCAGRSDFSGVPAPDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLILSMDANQTI WGAQLKRLKVGATRRFSATDRDSLVQDLRKILAPDYARRAREIAARMTKPADSVMKAADVVEDFVQSRSR TGRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3265 | - | - | 100% (425) | glycosyl transferase |
| M. avium 104 | MAV_3258 | - | e-153 | 63.03% (422) | glycosyltransferase family protein 28 |
| M. avium 104 | MAV_3262 | - | e-147 | 65.04% (389) | glycosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1551 | - | 1e-139 | 60.43% (417) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_3984 | - | 2e-07 | 26.29% (251) | UDP-glucuronosyl/UDP-glucosyltransferase |
| M. tuberculosis H37Rv | Rv1524 | - | 1e-139 | 60.43% (417) | glycosyltransferase |
| M. leprae Br4923 | MLBr_02348 | - | 1e-132 | 58.12% (425) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4107c | - | 0.0 | 76.37% (419) | glycosyltransferase GtfA |
| M. marinum M | MMAR_2353 | - | 1e-127 | 54.57% (416) | UDP-glycosyltransferase |
| M. smegmatis MC2 155 | MSMEG_0389 | - | 0.0 | 75.18% (419) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1989 | - | 1e-50 | 65.52% (145) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_1529 | - | 1e-105 | 53.80% (355) | UDP-glycosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2401 | - | 6e-06 | 25.82% (244) | UDP-glucuronosyl/UDP-glucosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1551|M.bovis_AF2122/97 MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
Rv1524|M.tuberculosis_H37Rv MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSA
MMAR_2353|M.marinum_M MKFALAINGTRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLEA
MUL_1529|M.ulcerans_Agy99 ----MSNRALHSGGNYRAEATKDAS--------QYPPNLTGVAAAAGLEA
MLBr_02348|M.leprae_Br4923 MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAA
MAB_4107c|M.abscessus_ATCC_199 MKFVLASYGTRGDIEPSVVVARELQRRGHDVVMAVPPDLISFTESAGLET
MSMEG_0389|M.smegmatis_MC2_155 MKFVLASYGTRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLRT
MAV_3265|M.avium_104 MKCVLASYGTRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLTA
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK MRVAVVAGPDPGHAFPALELCRRFRAAGDAPTLLTGTRWLDVARGEGVDA
Mvan_2401|M.vanbaalenii_PYR-1 MRVAVVAGPDPGHAFPAIALCLRFLAAGDHPTLLTGTKWLDTARREGVDA
Mb1551|M.bovis_AF2122/97 VAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAEL
Rv1524|M.tuberculosis_H37Rv VAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAEL
MMAR_2353|M.marinum_M VPYGP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDM
MUL_1529|M.ulcerans_Agy99 VPYCP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSDM
MLBr_02348|M.leprae_Br4923 VAYGP-DTQEFLARDT---YSQWRQWWKILPPIKALQQ----LRQAWADM
MAB_4107c|M.abscessus_ATCC_199 VSYGL-DTKTWLDVYRNFWTFFFHTFWKVREIRTMWRQMWELSDECWAQM
MSMEG_0389|M.smegmatis_MC2_155 VAYGL-DTKTWLDIYRNFWTFALHRFWKAREIRSLWREMWDLSDECWAQM
MAV_3265|M.avium_104 VPYGL-DSQAWLDVYRNFWTSFFRGFWKMGEMRGMWREMWDLSDQCWAQM
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK VELDGLDPTAFDDDTD----AGEKIHRRAARMAVLNRARIGELSPDLVVS
Mvan_2401|M.vanbaalenii_PYR-1 VELLGLDPTADDDDTD----AGAKIHHRAARMAVLNKDPIAALAPDLVIS
Mb1551|M.bovis_AF2122/97 SAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIA
Rv1524|M.tuberculosis_H37Rv SAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEIA
MMAR_2353|M.marinum_M AGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNSRVI
MUL_1529|M.ulcerans_Agy99 AGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSRVNSRVI
MLBr_02348|M.leprae_Br4923 ATDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPARVNGKII
MAB_4107c|M.abscessus_ATCC_199 NTTLMSAAQGADVLFAGQSYQEPAANVAEYHDIPLVTLHHIPMRPNGQLV
MSMEG_0389|M.smegmatis_MC2_155 NATLRSVAADADVLFAGQSYQEPAANVAEFYDVPLVTLHHIPMRPNGRLV
MAV_3265|M.avium_104 NTTLLSLADGADLLFAGQSYQEPAANVAEYYDLPLATLHHVPMRPNGQVV
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK DSITVCGGLAADLLGVPWVELNTHPLYRPSRGLPPVGSGLAPGVG-----
Mvan_2401|M.vanbaalenii_PYR-1 DSITTCGGLAADLLGLPWAELNTHPLYHPSKGLPPIGSGLAPGTG-----
Mb1551|M.bovis_AF2122/97 FPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMA
Rv1524|M.tuberculosis_H37Rv FPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRMA
MMAR_2353|M.marinum_M P--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRIL
MUL_1529|M.ulcerans_Agy99 P--ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASSSSTSRIL
MLBr_02348|M.leprae_Br4923 P--SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRIV
MAB_4107c|M.abscessus_ATCC_199 T--ILPSRLGRAAMRAFDWVSWRLNKKVEDAQRRELRLPKASSPSPQRIA
MSMEG_0389|M.smegmatis_MC2_155 T--FLPPVLARASMTAFDWFAWRLNKKVEDAQRRDLGLPKATGPSTQRIA
MAV_3265|M.avium_104 S--VLPAPLARSAMTAFDWFCWRLNKKVEDAQRRELGLPKATGPSPRRIA
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK ----LRGRARDAVLRALTARSWRAGLRQRAAARVEIGLPGDDPGPVRRLI
Mvan_2401|M.vanbaalenii_PYR-1 ----LRGRLRDAVLRALSARSWRAGLRQRSEARVGIGLPAADPGPVCRLI
Mb1551|M.bovis_AF2122/97 VRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDEVASW
Rv1524|M.tuberculosis_H37Rv VRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDEVASW
MMAR_2353|M.marinum_M KGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSW
MUL_1529|M.ulcerans_Agy99 KGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNEVLSW
MLBr_02348|M.leprae_Br4923 KRGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNEVLSW
MAB_4107c|M.abscessus_ATCC_199 ERRSLEIQGYDSVCFPGLATEWAKWNGLRPFVGSLTMAMTQEADEEVASW
MSMEG_0389|M.smegmatis_MC2_155 DRMSLEVQAYDEVCFPGLAEEWAKWGELRPYVGTLTMELTTPADEEVSSW
MAV_3265|M.avium_104 ERGSLEIQAYDEVCFPGLAEEWAKWDGQRPFVGTLTMELTTEADDEVMSW
TH_1989|M.thermoresistible__bu --------------------------------------------------
Mflv_3984|M.gilvum_PYR-GCK AT------------LPALEVPRPDWPAEAVVVGPLHFEPTT----ELLAV
Mvan_2401|M.vanbaalenii_PYR-1 AT------------LPALEVPRPDWPADAVVVGPLHFEPTT----HVLRL
Mb1551|M.bovis_AF2122/97 IAADTPPIYFGFGSMPIGSL-ADRVAMISAACAELGERALICSGPSDATG
Rv1524|M.tuberculosis_H37Rv IAADTPPIYFGFGSMPIGSL-ADRVAMISAACAELGERALICSGPSDATG
MMAR_2353|M.marinum_M IASGTPPIYFGFGSMPVESP-AATIAMISAACAELGERALICTGSNDLGG
MUL_1529|M.ulcerans_Agy99 IASGTPPIYFGFGSMPVESP-AATIAIISAACAELGERALICTGSNDLGG
MLBr_02348|M.leprae_Br4923 IAAGTPPIYFGFGSMPIVSP-TDTVAMIAAACADLGERALISVKPKDLTQ
MAB_4107c|M.abscessus_ATCC_199 IAGGTPPIFFGFGSMPVESP-SAALEMIGSACAELGERALIGAGWSDFGG
MSMEG_0389|M.smegmatis_MC2_155 ICGGTPPICFGFGSMPVESP-ADTVAMISSVCAELGERALICAGWSDFSD
MAV_3265|M.avium_104 IRGGTPPICFGFGSMPVESP-ADTVDMIGTACAQLGERALLCAGRSDFSG
TH_1989|M.thermoresistible__bu --------------------------MFASVCSRLGERALICAGGTDIDG
Mflv_3984|M.gilvum_PYR-GCK PAGGGPLVVVAPSTATTGAGGMAELALNTLVPGDTLPPGARVAVSQLDGP
Mvan_2401|M.vanbaalenii_PYR-1 PAGDGPVVVVAPSTATTGAVGLAELALATLVPGEVLPEGARVVVSRLEGP
: . . .
Mb1551|M.bovis_AF2122/97 IPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVT
Rv1524|M.tuberculosis_H37Rv IPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVT
MMAR_2353|M.marinum_M LQAPENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLILWIW
MUL_1529|M.ulcerans_Agy99 LQAPENVKLVSGVSHAAVFPACCAVVHHGGAGTTAAGMRAGIPTLILWIW
MLBr_02348|M.leprae_Br4923 VPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLILWIF
MAB_4107c|M.abscessus_ATCC_199 AQLPEHVKVVGAVNYATVFPACRAVVHHGGSGTTAASLRAGVPTLILSMD
MSMEG_0389|M.smegmatis_MC2_155 VALADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVLSMD
MAV_3265|M.avium_104 VPAPDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLILSMD
TH_1989|M.thermoresistible__bu VPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVTWSS
Mflv_3984|M.gilvum_PYR-GCK DSAVPPWAVVGLGRQDELLARADLLICGGGHGTVAKSLLAGVPMVVVPGG
Mvan_2401|M.vanbaalenii_PYR-1 DAEVPPWAVVGLGRQDELLAKADLLICGGGHGTVAKSLLAGVPMVVVPGG
:* ::. . :: ** **.* : **:* ::
Mb1551|M.bovis_AF2122/97 SDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILA-PDYVTRAREIA
Rv1524|M.tuberculosis_H37Rv SDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILA-PDYVTRAREIA
MMAR_2353|M.marinum_M IEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILG-PDYVARARTIA
MUL_1529|M.ulcerans_Agy99 IEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILG-PDYVARP----
MLBr_02348|M.leprae_Br4923 IEQPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILA-PQYATRAREVA
MAB_4107c|M.abscessus_ATCC_199 ANQTLWGGQVKKLKVGTTRRFSTTTRESLVADLRRILA-SDYADRARELA
MSMEG_0389|M.smegmatis_MC2_155 ANQALWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILD-PAYAARAQALA
MAV_3265|M.avium_104 ANQTIWGAQLKRLKVGATRRFSATDRDSLVQDLRKILA-PDYARRAREIA
TH_1989|M.thermoresistible__bu ADQPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILT-PDYAVRARAVA
Mflv_3984|M.gilvum_PYR-GCK GDQ--WEIANRLVRQGSAQLVRPLSAESLAAAVREVLGSPSYREAAVRAG
Mvan_2401|M.vanbaalenii_PYR-1 GDQ--WEIANRLVRQGSAQLVRPLTGSTLTAAVQEVLGSPGYREAARRAG
:* * : :: * : . :* :: :* . * .
Mb1551|M.bovis_AF2122/97 SRMTKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv SRMTKPAASVTATADLLEDAARRAR--------
MMAR_2353|M.marinum_M NEMSKPGESATRAADLLENEVSVS---------
MUL_1529|M.ulcerans_Agy99 -----PG--LRRC--------------------
MLBr_02348|M.leprae_Br4923 NRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
MAB_4107c|M.abscessus_ATCC_199 AGMTKPGESAVAAADAMERFAQARCSA------
MSMEG_0389|M.smegmatis_MC2_155 RGMTRPAESVVRAADVIEAFARSRCSA------
MAV_3265|M.avium_104 ARMTKPADSVMKAADVVEDFVQSRSRTGRS---
TH_1989|M.thermoresistible__bu ARMTDPADSVVRAADLFETAVECAPGVAHRE--
Mflv_3984|M.gilvum_PYR-GCK AGVADVADPVRVCHDALGAPRKLGPCG------
Mvan_2401|M.vanbaalenii_PYR-1 AGVADVADPVRVCHAALGAPA------------