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MSVDYEVRNGVAWLTINRPEARNSLNKAVRDGLFDGVRRFNNDAQAKVLVLTGAGDKAFCAGGDLKEMSD DQLTVPPIDFVPQFGRNITVDKPTIAAVNGVAFAGGFLLAQTCDLCVASTTAKFAITEAKVGRGSPWAAP LPLMIPRRIAMELVLTGAPISAARAHEIGFVNRLAEPADLHAVAQKLAEQIAANAPLSVAAGKRTATLTA EHPLSEAFDIAESIWEPVYLSGDAQEGMAAFKEKRSPVWKGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0335 | - | - | 100% (252) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_5198 | - | 6e-43 | 41.31% (259) | carnitinyl-CoA dehydratase |
| M. smegmatis MC2 155 | MSMEG_2227 | - | 1e-39 | 43.03% (251) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 1e-32 | 39.23% (260) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4596 | - | 7e-95 | 66.93% (251) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 6e-41 | 43.82% (251) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-30 | 34.29% (245) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2058 | - | 6e-95 | 67.87% (249) | enoyl-CoA dehydratase/isomerase |
| M. marinum M | MMAR_0465 | echA1 | 1e-41 | 45.42% (251) | enoyl-CoA hydratase EchA1 |
| M. avium 104 | MAV_1277 | - | 2e-42 | 41.15% (260) | carnitinyl-CoA dehydratase |
| M. thermoresistible (build 8) | TH_4462 | - | 3e-41 | 38.87% (247) | PUTATIVE putative enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0972 | echA1_1 | 5e-42 | 41.09% (258) | enoyl-CoA hydratase, EchA1_1 |
| M. vanbaalenii PYR-1 | Mvan_0344 | - | 1e-120 | 84.06% (251) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0335|M.smegmatis_MC2_155 -----------MSVDYEVRNGVAWLTINRPEARNSLNKAVRDGLFDGVRR
Mvan_0344|M.vanbaalenii_PYR-1 -----------MSVTYTVRNGVAWLTIDRPDARNSLNKAVRDGLFDGVRR
Mflv_4596|M.gilvum_PYR-GCK --------MSEEAITYEVVDGVAWLTINRPEARNALNGAVRQGLFHSVHR
MAB_2058|M.abscessus_ATCC_1997 --------MAEQPIRYEVVDSVAWLTINRPEARNALNNAVRTGLIDAVLR
MAV_1277|M.avium_104 ---MTDA----PGALAERRGNVMVITINRPEARNAVNAAVSIGVGDALEE
MUL_0972|M.ulcerans_Agy99 ---MTDAGDDQPAGLVEHRGNVMVITINRPEARNAINGAVSVAVGGALES
Rv0222|M.tuberculosis_H37Rv MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQ
MMAR_0465|M.marinum_M MSELN--GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAMDR
TH_4462|M.thermoresistible__bu MTAPTTARQATDPVLVSADSHVLTITLNRPDVHNAVNLDMAQRISDALDR
Mb3545|M.bovis_AF2122/97 -------MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDR
MLBr_02402|M.leprae_Br4923 --------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKE
:*::** . *::. : : .
MSMEG_0335|M.smegmatis_MC2_155 FNNDAQAKVLVLTGAGDKAFCAGGDLKEMSD----DQLTVP--PIDFVPQ
Mvan_0344|M.vanbaalenii_PYR-1 FNADTAAKVLVLTGAGDKAFCAGGDLKEMSA----DGLTIP--PVDFVPQ
Mflv_4596|M.gilvum_PYR-GCK FNADDSAKVLVLTGAGDKAFCAGGDLKEMAE----TALTVP--PPDFAPQ
MAB_2058|M.abscessus_ATCC_1997 FNDDDAAKVLVLTGVGDKAFCAGGDLKEMAQ----NALKVP--PKDFAPQ
MAV_1277|M.avium_104 AQHDPEVRAVVLTGAGDKSFCAGADLKAIAR---RENLYHP-DHPEWGFA
MUL_0972|M.ulcerans_Agy99 AQNDAEVRAVVITGAGDKSFCAGADLLAISR---RENIYHP-DHNEWGFA
Rv0222|M.tuberculosis_H37Rv LDGDAGLSVAILTGGG-GSFCAGMDLKAFAR---GENVVV----EGRGLG
MMAR_0465|M.marinum_M LDADAGLSVGILTGAG-GSFCAGMDLKAFAR---GENVVV----EGRGLG
TH_4462|M.thermoresistible__bu LDDDPDLRVGIIAANG-RSFCAGMDLKAFAR---GEVPRP----EPRGFA
Mb3545|M.bovis_AF2122/97 VDNDPDIRCCILTGAG-GYFCAGMDLKAATQKPPGDSFKDGSYDPSRIDA
MLBr_02402|M.leprae_Br4923 LDIDPDVGAILITGSP-KVFAAGADIKEMAS-----LTFTDAFDADFFSA
: * :::. *.** *: :
MSMEG_0335|M.smegmatis_MC2_155 FGRNITVDKPTIAAVNGVAFAGGFLLAQTCDLCVASTTAKFAITEAKVG-
Mvan_0344|M.vanbaalenii_PYR-1 FGRNIKVDKPTIAAVNGAAFAGGFLLAQTCDLCVASTTATFGITEVKVG-
Mflv_4596|M.gilvum_PYR-GCK FGRNIQVAKPTIAAVNGVAFAGGFLLAQQCDLVIAAEHARFAVSEVKVG-
MAB_2058|M.abscessus_ATCC_1997 FGRNIDVAKPTIAAVNGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG-
MAV_1277|M.avium_104 GYVRHFIDKPTIAAVNGTALGGGTELALASDLVVADERAQFGLPEVKRGL
MUL_0972|M.ulcerans_Agy99 GYVHHFIDKPTIAAVNGTALCGGTELALASDLVVADERAKFGLPEAKRGF
Rv0222|M.tuberculosis_H37Rv -FTERPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRGL
MMAR_0465|M.marinum_M -FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRGL
TH_4462|M.thermoresistible__bu GIVKQPPAKPLVAAVEGAAVGGGFEIVLACDLIVASESARFSLPEVTRGL
Mb3545|M.bovis_AF2122/97 LLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSL
MLBr_02402|M.leprae_Br4923 WGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
.* :*** * *. ** : *: :* : *. .* . .
MSMEG_0335|M.smegmatis_MC2_155 -RGSPWAAPLPLMIPRRIAMELVLTGAPISAARAHEIGFVNRLAEPADLH
Mvan_0344|M.vanbaalenii_PYR-1 -RGSPWAAPLPLMIPRRVVMELVLTGAPMSARRAHEIGFVNRLAEPSDLV
Mflv_4596|M.gilvum_PYR-GCK -RGSPWAVPLSWLLPPRIALQILMTGDPITAERAREVGMVNEVVPAAELR
MAB_2058|M.abscessus_ATCC_1997 -RGSPWATPLSWLVPPRVAMQILLTGDPITAARAHQVGLVNEVVPADQLR
MAV_1277|M.avium_104 IAAAGGVFRIAEQLPRKVAMRLLLTGEPLSAAAARDWGLINEVVEAGSVL
MUL_0972|M.ulcerans_Agy99 IAAAGGVFRIVNQLPRKVAMEMLLTGEPITASDAYEWGLINQVVKQGAVL
Rv0222|M.tuberculosis_H37Rv VAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTAL
MMAR_0465|M.marinum_M VAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAAL
TH_4462|M.thermoresistible__bu TPNGGGLLRLPRRIPHHLAMELILTGRPVTAARAAELGLLNRLTPPGSAL
Mb3545|M.bovis_AF2122/97 YPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQAL
MLBr_02402|M.leprae_Br4923 LPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLL
: : . : :** : * * *::. :.
MSMEG_0335|M.smegmatis_MC2_155 AVAQKLAEQIAANAPLSVAAGKRTATLTAE---HPLSEAFDIAESIWEPV
Mvan_0344|M.vanbaalenii_PYR-1 DSTQALAEQIAANAPLSVAAGKATAVLTAE---YPLSEAYDHAERLWQEV
Mflv_4596|M.gilvum_PYR-GCK VRVQEIALRIASNAPLSVLAAKKTVYLSAA---HHLTEAYAHADQIWEPV
MAB_2058|M.abscessus_ATCC_1997 ERTQQLALSIAANAPLSVLASKRTVYLSAQ---HHLAAAYDLADEIWEPV
MAV_1277|M.avium_104 DAALALASAITVNAPLSVQASKRIAYGVDDGVVVGDEPGWDRTMREMRAL
MUL_0972|M.ulcerans_Agy99 DAALALAARVTVNAPLSVRASKRIAYGVDDGVVADEERGWERTMREMRSL
Rv0222|M.tuberculosis_H37Rv DAAIALAEKITANGPLAVVATKRIITESRG---WSPDTMFAEQMKILVPV
MMAR_0465|M.marinum_M DAAIALAEKITANGPLAVAATKRIITESRG---WSLDTRFAQQMKILFPI
TH_4462|M.thermoresistible__bu STARELAAVIAANGPLAIRAAKRVVEESPD---WPRTEMFTRQEDIVAPV
Mb3545|M.bovis_AF2122/97 TKALELADAISANGPLAVQAILRSIRETEC---MPENEAFKIDTQIGIKV
MLBr_02402|M.leprae_Br4923 PEAKAVATTISQMSRSATRMAKEAVNRSFES---TLAEGLLHERRLFHST
. :* :: . :
MSMEG_0335|M.smegmatis_MC2_155 YLSGDAQEGMAAFKEKRSPVWKGR
Mvan_0344|M.vanbaalenii_PYR-1 YLSSDAQEGMQAFKDKRAPVWKGI
Mflv_4596|M.gilvum_PYR-GCK YLSADALEGPAAFREKRTPVWKGR
MAB_2058|M.abscessus_ATCC_1997 YLSDDAQEGPAAFREKRAPQWKGH
MAV_1277|M.avium_104 LKSEDAKEGPRAFAEKREPVWQAR
MUL_0972|M.ulcerans_Agy99 IRSEDAKEGPLAFAEKREPVWKTR
Rv0222|M.tuberculosis_H37Rv FTSNDAKEGAIAFAERRRPRWTGT
MMAR_0465|M.marinum_M FTSNDAKEGAIAFAEKRPPRWTGT
TH_4462|M.thermoresistible__bu RSSADAAEGARAFAEKRMPLWRNR
Mb3545|M.bovis_AF2122/97 FLSDDAKEGPRAFAEKRAPNFQNR
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR
: * ** ** ::* * :