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M. thermoresistible (build 8) TH_4462 (-)

annotation: putative enoyl-CoA hydratase
coordinates: 259764 - 260555
length: 264

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4462 - - 100% (264) putative enoyl-CoA hydratase
M. thermoresistible (build 8) TH_3963 - 2e-74 57.42% (256) PUTATIVE enoyl-CoA hydratase
M. thermoresistible (build 8) TH_3131 - 2e-51 44.00% (250) PUTATIVE putative enoyl-CoA hydratase EchA1

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3545 echA19 5e-52 44.92% (256) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_4354 - 2e-72 56.80% (250) enoyl-CoA hydratase
M. tuberculosis H37Rv Rv0222 echA1 4e-69 53.08% (260) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 1e-35 35.83% (254) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_4588c - 7e-71 54.37% (252) enoyl-CoA hydratase/isomerase
M. marinum M MMAR_0465 echA1 3e-68 54.58% (251) enoyl-CoA hydratase EchA1
M. avium 104 MAV_4951 - 9e-73 56.81% (257) enoyl-CoA hydratase
M. smegmatis MC2 155 MSMEG_2227 - 3e-70 54.66% (247) enoyl-CoA hydratase
M. ulcerans Agy99 MUL_1114 echA1 2e-68 54.58% (251) enoyl-CoA hydratase
M. vanbaalenii PYR-1 Mvan_1990 - 3e-69 54.62% (249) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4354|M.gilvum_PYR-GCK          ----------MSDEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
Mvan_1990|M.vanbaalenii_PYR-1       ----------MADEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
MSMEG_2227|M.smegmatis_MC2_155      ----------MSEEVVLRERRDRTLIITINRPEARNAFNLAVAKGLAEAV
MMAR_0465|M.marinum_M               MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
MUL_1114|M.ulcerans_Agy99           MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
Rv0222|M.tuberculosis_H37Rv         MSSESDA--ANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAM
MAV_4951|M.avium_104                MRHVSTGNEEAGEPEVLVEQRDRILIITINRPKAKNAVNAAVANGLAAAV
MAB_4588c|M.abscessus_ATCC_199      -----------MADEVLIEQRDRVLLITINRPDARNAVNRAVSQGLAAAA
TH_4462|M.thermoresistible__bu      --MTAPTTARQATDPVLVSADSHVLTITLNRPDVHNAVNLDMAQRISDAL
Mb3545|M.bovis_AF2122/97            ---------MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAW
MLBr_02402|M.leprae_Br4923          ----------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAA
                                                    * .   :   :*:*** . *:..  : . :  * 

Mflv_4354|M.gilvum_PYR-GCK          DELDDTPELSVAIITGAGGNFCAGMDLKAFMAG-------EVPAIEGRGI
Mvan_1990|M.vanbaalenii_PYR-1       DELDSSAELSVAIITGAGGNFCAGMDLKAFMAG-------EVPAIEGRGI
MSMEG_2227|M.smegmatis_MC2_155      DELDDTQELSVGIITGAGGTFCAGMDLKGFASG-------ELPHVPGRGI
MMAR_0465|M.marinum_M               DRLDADAGLSVGILTGAGGSFCAGMDLKAFARG-------ENVVVEGRGL
MUL_1114|M.ulcerans_Agy99           DRLDADAGLSVGILTGAGGSFCAGMDLKAFARG-------ENVVVEGRGL
Rv0222|M.tuberculosis_H37Rv         DQLDGDAGLSVAILTGGGGSFCAGMDLKAFARG-------ENVVVEGRGL
MAV_4951|M.avium_104                DRLDSEPGLSVGVLTGAGGSFCAGMDLKAFARG-------ELPIVEGRGM
MAB_4588c|M.abscessus_ATCC_199      DQLDSSADLSVAIITGAGGNFCAGMDLKAFVSG-------EAVLSE-RGL
TH_4462|M.thermoresistible__bu      DRLDDDPDLRVGIIAANGRSFCAGMDLKAFARG-------EVPRPEPRGF
Mb3545|M.bovis_AF2122/97            DRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPPGDSFKDGSYDPSRID
MLBr_02402|M.leprae_Br4923          KELDIDPDVGAILITGSPKVFAAGADIKEMASLT-----FTDAFDADFFS
                                    ..:*    :   :::.    *.** *:*                      

Mflv_4354|M.gilvum_PYR-GCK          G-FTERPPRKPLIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
Mvan_1990|M.vanbaalenii_PYR-1       G-FTERPPRKPVIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
MSMEG_2227|M.smegmatis_MC2_155      G-FTEKPPRKPLIAAVEGYALAGGTEIVLATDLVVASRTAKFGIPEVKRG
MMAR_0465|M.marinum_M               G-FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
MUL_1114|M.ulcerans_Agy99           G-FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
Rv0222|M.tuberculosis_H37Rv         G-FTERPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRG
MAV_4951|M.avium_104                G-FTERPPAKPLIAAVEGYALAGGTELALATDLIVASKDAAFGIPEVKRG
MAB_4588c|M.abscessus_ATCC_199      G-FTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRG
TH_4462|M.thermoresistible__bu      AGIVKQPPAKPLVAAVEGAAVGGGFEIVLACDLIVASESARFSLPEVTRG
Mb3545|M.bovis_AF2122/97            ALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWS
MLBr_02402|M.leprae_Br4923          AWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLG
                                    .        .*::*** * *:.** *:    *: :*.  : *. .* . .

Mflv_4354|M.gilvum_PYR-GCK          LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASAWGFVNVLTEPGGA
Mvan_1990|M.vanbaalenii_PYR-1       LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASQWGFVNVLTEPGEA
MSMEG_2227|M.smegmatis_MC2_155      LVAAGGGLLRLPKRIPYQKALELALTGDNFTAEEAAAWGFVNKLTEPGEA
MMAR_0465|M.marinum_M               LVAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
MUL_1114|M.ulcerans_Agy99           LAAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
Rv0222|M.tuberculosis_H37Rv         LVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTA
MAV_4951|M.avium_104                LVAGGGGLLRLPQRIPSAIAMELALTGDNLSAERAHALGMVNVLAEPGSA
MAB_4588c|M.abscessus_ATCC_199      LVAGAGGLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQA
TH_4462|M.thermoresistible__bu      LTPNGGGLLRLPRRIPHHLAMELILTGRPVTAARAAELGLLNRLTPPGSA
Mb3545|M.bovis_AF2122/97            LYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQA
MLBr_02402|M.leprae_Br4923          VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDL
                                    : .  *.  ** . *    * :* ***  . *  *   *::. :.  .  

Mflv_4354|M.gilvum_PYR-GCK          LDGALALAERITANGPLAVAATKEVIAKSADWTEAEMWKKQGEIVFPVFS
Mvan_1990|M.vanbaalenii_PYR-1       LNGALALAERITANGPLAVAVTKEVIVKSADWTEAEMWKKQGELVMSVFS
MSMEG_2227|M.smegmatis_MC2_155      LAGALELAERITANGPLAVAVTKEVIVKSAEWSEAEMWKKQGELIGPVFS
MMAR_0465|M.marinum_M               LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
MUL_1114|M.ulcerans_Agy99           LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
Rv0222|M.tuberculosis_H37Rv         LDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFT
MAV_4951|M.avium_104                LDEAIALAEKIAANGPLAVAATKRIIVESRGWSPETMFAEQNKLLAPVFS
MAB_4588c|M.abscessus_ATCC_199      LDTALELAAKITANGPLAVAATKRIIIESASWAPEEAFAKQGEILMPIFV
TH_4462|M.thermoresistible__bu      LSTARELAAVIAANGPLAIRAAKRVVEESPDWPRTEMFTRQEDIVAPVRS
Mb3545|M.bovis_AF2122/97            LTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFL
MLBr_02402|M.leprae_Br4923          LPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFV
                                    *  *  :*  *:  .  *     . : .:   .       :  :      

Mflv_4354|M.gilvum_PYR-GCK          SKDAMEGATAFAEKRKPNWTGT
Mvan_1990|M.vanbaalenii_PYR-1       SKDAMEGATAFAEKRKPNWTGS
MSMEG_2227|M.smegmatis_MC2_155      SKDAIEGATAFAEKRKPNWTGS
MMAR_0465|M.marinum_M               SNDAKEGAIAFAEKRPPRWTGT
MUL_1114|M.ulcerans_Agy99           SNDAKEGAIAFAEKRPPRWTGT
Rv0222|M.tuberculosis_H37Rv         SNDAKEGAIAFAERRRPRWTGT
MAV_4951|M.avium_104                SNDAKEGAIAFAEKRPPKWTGT
MAB_4588c|M.abscessus_ATCC_199      SEDAKEGAKAFAEKRAPVWQGK
TH_4462|M.thermoresistible__bu      SADAAEGARAFAEKRMPLWRNR
Mb3545|M.bovis_AF2122/97            SDDAKEGPRAFAEKRAPNFQNR
MLBr_02402|M.leprae_Br4923          TDDQSEGMAAFIEKRAPQFTHR
                                    : *  **  ** *:* * :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4462	-	-	100% (264)	putative enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_3963	-	2e-74	57.42% (256)	PUTATIVE enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_3131	-	2e-51	44.00% (250)	PUTATIVE putative enoyl-CoA hydratase EchA1