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MTEQSVAGSENAAHDIQRLKRNAVGTVGVIFMAVATAAPITAMVGNVPIAVGFGNGSHAPAGYFVATVVL GLFAIGYATMAKHITATGAFYGYISHGLGRIVGMAAGGLITMAYVVFEASLIGIFSFFFQNFLDSQLGIH IHWIIPALLMLATNAILTYFDVNLTAKVLGVFLVTEIVMLALGAVAVLFRGGGPDGFAVNEILNPAGAFS PATGIVGASAGLGLFFAFWSWVGFESTAMYGEESRNPKRIIPRATMIAVLGVGVFYVFISWMAIAGTGPQ QSIELAQDANTASEIFFAPVRDTYGEWAITVFNILLVTGSFACGMAFHNCASRYLYALGREGLSRGLQKT LGATHPTHGSPYIASFVQSAIALVIVLSFLFAGMDPYVHMYTLLAILGTMAILIVQSLCAFSVISYFHIH KNHPESKHWFKTLVAPGLGGLGMLYVVYLLWEHKDTAAGTASGTLLFKLTPWIVVSVFVLGAALATYFKL RDPRRYGLIGRIVYDEAVERD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0279 | - | - | 100% (511) | amino acid permease |
| M. smegmatis MC2 155 | MSMEG_0781 | - | 0.0 | 63.62% (514) | amino acid permease |
| M. smegmatis MC2 155 | MSMEG_1118 | - | e-141 | 50.51% (487) | amino acid permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 5e-20 | 23.48% (328) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_1244 | - | 0.0 | 83.10% (509) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2320c | rocE | 5e-20 | 23.48% (328) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01974 | - | 2e-12 | 26.64% (229) | putative permease |
| M. abscessus ATCC 19977 | MAB_0950c | - | 0.0 | 61.52% (512) | putative amino acid permease family protein |
| M. marinum M | MMAR_3621 | rocE | 1e-23 | 24.29% (490) | cationic amino acid transport integral membrane protein RocE |
| M. avium 104 | MAV_2087 | - | 8e-22 | 25.28% (360) | amino acid transporter |
| M. thermoresistible (build 8) | TH_0471 | - | 5e-16 | 23.01% (465) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_1244 | rocE | 1e-22 | 24.08% (490) | cationic amino acid transport integral membrane protein RocE |
| M. vanbaalenii PYR-1 | Mvan_5564 | - | 0.0 | 82.78% (511) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 --------------------------------------------------
Rv2320c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3621|M.marinum_M --------------------------------------------------
MUL_1244|M.ulcerans_Agy99 --------------------------------------------------
MAV_2087|M.avium_104 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mflv_1244|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5564|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0279|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0950c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01974|M.leprae_Br4923 MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
Mb2347c|M.bovis_AF2122/97 MPTTSMSLRELMLRRRPVSGAPVAS-------------------------
Rv2320c|M.tuberculosis_H37Rv MPTTSMSLRELMLRRRPVSGAPVAS-------------------------
MMAR_3621|M.marinum_M MPATSIRLREQMLRRRPVGGAPVAE-------------------------
MUL_1244|M.ulcerans_Agy99 MPATSIRLREQMLRRRPAGGAPVAE-------------------------
MAV_2087|M.avium_104 ----------------------MAP-------------------------
TH_0471|M.thermoresistible__bu -------MTDRLRVKSVEQSIADTD-------------------------
Mflv_1244|M.gilvum_PYR-GCK --------MTESAERTAPGQTTPTA-------------------------
Mvan_5564|M.vanbaalenii_PYR-1 -----------MTEDVVPRQTAPTD-------------------------
MSMEG_0279|M.smegmatis_MC2_155 -----------MTEQSVAGSENAAH-------------------------
MAB_0950c|M.abscessus_ATCC_199 ---------MSDTIDPPVGTTTEPD-------------------------
MLBr_01974|M.leprae_Br4923 LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
Mb2347c|M.bovis_AF2122/97 --GASGNLKRSFGTFQLTMFGVG-ATIGTGIFFVLAQAVP-EAGPGVIVS
Rv2320c|M.tuberculosis_H37Rv --GASGNLKRSFGTFQLTMFGVG-ATIGTGIFFVLAQAVP-EAGPGVIVS
MMAR_3621|M.marinum_M --GAAGSLKRSFGTFELTMFGVG-STVGTGIFFVLAEAVP-EAGPAVIVS
MUL_1244|M.ulcerans_Agy99 --GAAGSLKRSFGTFELTMFGVG-STVGTGIFFVLAEAVP-EAGPAVIVS
MAV_2087|M.avium_104 --GTADHLRRGIGTFQLTMFGVG-STIGTGIFFVMSQAVP-EAGPAVIVS
TH_0471|M.thermoresistible__bu --EPDSRLRKDLSWWDLTVFGVS-VVIGAGIFTVTASTAGNITGPAISVS
Mflv_1244|M.gilvum_PYR-GCK --SVQRLKRNAVGTFGVIFMAVATAAPITAMVGNVPIAVGFGNGSHAPAG
Mvan_5564|M.vanbaalenii_PYR-1 --SVQRLKRNAVGTFGVIFMAVATAAPITAMVGNVPIAVGFGNGSHAPAG
MSMEG_0279|M.smegmatis_MC2_155 --DIQRLKRNAVGTVGVIFMAVATAAPITAMVGNVPIAVGFGNGSHAPAG
MAB_0950c|M.abscessus_ATCC_199 --SMQRLKPNAVGLIGVLFMAVATAAPITAMVGNVPMAVGFGNGAYAPAG
MLBr_01974|M.leprae_Br4923 IRGQGGRAISKLGFWSVVMLGIN-SIIGAGIFMTPGEVIK-IAGPFAPIA
.. : .:.: :.:. . *. .
Mb2347c|M.bovis_AF2122/97 FIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLL
Rv2320c|M.tuberculosis_H37Rv FIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLL
MMAR_3621|M.marinum_M FIIAGVAAGLAAICYAELASAVPVSGSSYSYAYATLGEAVAMGVASCLLL
MUL_1244|M.ulcerans_Agy99 FIIAGVAAGLAAICCAELASAVPVSGSSYSYAYATLGEAVAMGVASCLLL
MAV_2087|M.avium_104 FLLAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLL
TH_0471|M.thermoresistible__bu FIIAAIACGLAALCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLIL
Mflv_1244|M.gilvum_PYR-GCK YLVATIVLGLFAIGYATMAKHITATGAFYGYISHGLGRVMGMASGLIITL
Mvan_5564|M.vanbaalenii_PYR-1 YLVATVVLGLFAIGYATMAKHITATGAFYGYISHGLGRVMGMASGGIITM
MSMEG_0279|M.smegmatis_MC2_155 YFVATVVLGLFAIGYATMAKHITATGAFYGYISHGLGRIVGMAAGGLITM
MAB_0950c|M.abscessus_ATCC_199 YLVATIVLTLFAIGYAAMSRHIVATGAFYGYISHGLGRVVGLGSGFLITL
MLBr_01974|M.leprae_Br4923 YTLAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAI
: :* : : *: * : : *: * : :*. :. . :
Mb2347c|M.bovis_AF2122/97 EYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPG----WVN
Rv2320c|M.tuberculosis_H37Rv EYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPG----WVN
MMAR_3621|M.marinum_M EYGVATAAVAVGWSGYVNKLLHNVFGFQLPQALSEAPWDERPGEAAGYLN
MUL_1244|M.ulcerans_Agy99 EYGVATAAVAVGLSGYVNKLLHNVFGFQLPQALSEAPWDERPGEAAGYLN
MAV_2087|M.avium_104 EYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWDAQPG----YVN
TH_0471|M.thermoresistible__bu EFSVAAAVVAKGWSSYLG----EVFEFAG-ATTRLGPITLDWG-------
Mflv_1244|M.gilvum_PYR-GCK AYIVFEASLIGIFAFFFQNFLSSQLGITIHWLVPALLMLVLNS---ILTY
Mvan_5564|M.vanbaalenii_PYR-1 AYVVFEASLIGIFAFFFQNFLSSQFGFDIHWLIPALLMLALNC---ILTY
MSMEG_0279|M.smegmatis_MC2_155 AYVVFEASLIGIFSFFFQNFLDSQLGIHIHWIIPALLMLATNA---ILTY
MAB_0950c|M.abscessus_ATCC_199 AYMVFEASLVGIFSFFANDLFQTFFQVDVPWVVFAVAMLATNA---VLTY
MLBr_01974|M.leprae_Br4923 TASIAWGVLAS---SFVSTLLRVAFPEKIWADNDELISVKTLTFLVFIAV
: . : : .
Mb2347c|M.bovis_AF2122/97 LPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSAD
Rv2320c|M.tuberculosis_H37Rv LPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSAD
MMAR_3621|M.marinum_M LPAIILIGLCALLLIRGVSESAKVNAIMVLIKLGVLGMFVILALTAYDTN
MUL_1244|M.ulcerans_Agy99 LPAIILIGLCALLLIRGVSESAKVNAIMVLIKLGVLGMFVILALTAYDTN
MAV_2087|M.avium_104 LPAVMLIGMCALLLIRGASESAKVNAIMVMVKLGVLVVFGILAFTAFDMH
TH_0471|M.thermoresistible__bu --ALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVIVGAFFIKAA
Mflv_1244|M.gilvum_PYR-GCK FDVNLTAKVLGVFLITEIFMLALGAVAVAVKGGGPDGFAIAETLNPVGAF
Mvan_5564|M.vanbaalenii_PYR-1 FDVNLTAKVLGVFLVTEIVMLSLGAIAVAVKGGGPDGFAVGEILNPVGAF
MSMEG_0279|M.smegmatis_MC2_155 FDVNLTAKVLGVFLVTEIVMLALGAVAVLFRGGGPDGFAVNEILNPAGAF
MAB_0950c|M.abscessus_ATCC_199 FDLNLAARVLGVFLVTEILMLSLLALSVLFAGGGPQGWSWGS-LNPLNGF
MLBr_01974|M.leprae_Br4923 LLAINIFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQHVNNYVTSR
: . . *
Mb2347c|M.bovis_AF2122/97 HLKDFVP---------------------------FGVAGIGSAAGTIFFS
Rv2320c|M.tuberculosis_H37Rv HLKDFVP---------------------------FGVAGIGSAAGTIFFS
MMAR_3621|M.marinum_M HLKDFAP---------------------------FGVAGVGAAAGTIFFS
MUL_1244|M.ulcerans_Agy99 HLKDFAP---------------------------FGVAGVGAAAGTIFFS
MAV_2087|M.avium_104 HLDDFAP---------------------------FGVAGVGTAAGTIFFS
TH_0471|M.thermoresistible__bu NYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLLAGASIVFFA
Mflv_1244|M.gilvum_PYR-GCK QPAA-IAG-----------------------------ASAGLGLFFAFWS
Mvan_5564|M.vanbaalenii_PYR-1 QPAA-IAG-----------------------------ASAGLGLFFAFWS
MSMEG_0279|M.smegmatis_MC2_155 SPATGIVG-----------------------------ASAGLGLFFAFWS
MAB_0950c|M.abscessus_ATCC_199 HDLGGVVQGPAG--------------------PLAVAGSAGVGLFFAFWS
MLBr_01974|M.leprae_Br4923 SAYQPTTYSLLG----------------VTEIGKSTAASMTLATIVALYA
. . :::
Mb2347c|M.bovis_AF2122/97 YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALG----T
Rv2320c|M.tuberculosis_H37Rv YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALG----T
MMAR_3621|M.marinum_M FIGLDAVSTAGEEVRNPQQSVPRALIAALFVVTGVYVLVAFAALG----T
MUL_1244|M.ulcerans_Agy99 FIGLDAVSTAGEEVRNPQQSVPRALIAALFVVTGVYVLVAFAALG----T
MAV_2087|M.avium_104 YIGLDAVSTAGDEVTNPQKTMPRALIAALLTVTGVYVFVALAALG----T
TH_0471|M.thermoresistible__bu FIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSLVLTG----M
Mflv_1244|M.gilvum_PYR-GCK WVGFESTAMYGEESKDPKRIIPRATMIAVLGVGIFYVFVSWMAIAGTGPQ
Mvan_5564|M.vanbaalenii_PYR-1 WVGFESTAMYGEESKDPKRIIPRATMIAVLGVGLFYVFVSWMAIAGTGPK
MSMEG_0279|M.smegmatis_MC2_155 WVGFESTAMYGEESRNPKRIIPRATMIAVLGVGVFYVFISWMAIAGTGPQ
MAB_0950c|M.abscessus_ATCC_199 WVGFESSAMYAEESKNPKKIIPIAIVTSVVGVGLFYVLVSWLAIVGTGPE
MLBr_01974|M.leprae_Br4923 FTGFESIANAAEEMNTPDRTLPKAIPLTILTVGVIYILALVVAML-----
: *:: : .:* *.: :. . :: * .*:
Mb2347c|M.bovis_AF2122/97 QPWQDFAEQ-ETAGLAIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYG
Rv2320c|M.tuberculosis_H37Rv QPWQDFAEQ-ETAGLAIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYG
MMAR_3621|M.marinum_M QPWQMFAGQ-EEAGLATILDNVTHSAWASTVLAMGAVISIFTVTLVTMYG
MUL_1244|M.ulcerans_Agy99 QPWQMFAGQ-EEAGLATILDNVTHSAWASTVLAMGAVISIFTVTLVTMYG
MAV_2087|M.avium_104 QPWQDFGGQ-QEAGLATILDHVTHGSWASTILAAGAVISIFSVTLVTMYG
TH_0471|M.thermoresistible__bu VHYTELRAAGENANLATAFA-ANGIDWAAKVISIGALAGLTTVVIVLVLG
Mflv_1244|M.gilvum_PYR-GCK QAVELAQSADTSSEIFFAPVRDTYGEWAITLFNILLVTGSFACGMAFHNC
Mvan_5564|M.vanbaalenii_PYR-1 QAVELAQSADTSSEIFFAPVRTTYGEWAITLFNILLVSGSFACGMAFHNC
MSMEG_0279|M.smegmatis_MC2_155 QSIELAQDANTASEIFFAPVRDTYGEWAITVFNILLVTGSFACGMAFHNC
MAB_0950c|M.abscessus_ATCC_199 NAVALAQDSSTAGNIFFGPVQSHLGVWAVNLFKVLLMTGSFACGMAFHNC
MLBr_01974|M.leprae_Br4923 ----LGSDKIVATNHTVKLAAAVGNNTFRTIIVVGALVSMFGINVAASFG
.:: : . :.
Mb2347c|M.bovis_AF2122/97 QTRILFAMGRDGLLP---ARFAKVNPRTMTPVHNTVIVAIFASTLAAFIP
Rv2320c|M.tuberculosis_H37Rv QTRILFAMGRDGLLP---ARFAKVNPRTMTPVHNTVIVAIFASTLAAFIP
MMAR_3621|M.marinum_M QTRILFAMGRDGLLP---ARFAAVHPRFQTPVSNTVVVAIAAAVLAALVP
MUL_1244|M.ulcerans_Agy99 QTRILFAMGRDGLLP---ARFAAVHPRFQTPVSNTVVVAIAAAVLAALVP
MAV_2087|M.avium_104 ITRILFAMGRDGLLP---PRFARVNPRTMTPVNNTVIVAVAAATLAAFIP
TH_0471|M.thermoresistible__bu QTRVLFAMSRDGLLP---RPLSKTGPR-GTPVRITVLVGALVAIAASVFP
Mflv_1244|M.gilvum_PYR-GCK ASRYLYALGREGLSTGLQKTLGATHKTHGSPYIASFVQSGIALVLVLAFF
Mvan_5564|M.vanbaalenii_PYR-1 ASRYLYALGREGLSTRLQDTLGATHKTHGSPHIASFVQTGITLVLILAFF
MSMEG_0279|M.smegmatis_MC2_155 ASRYLYALGREGLSRGLQKTLGATHPTHGSPYIASFVQSAIALVIVLSFL
MAB_0950c|M.abscessus_ATCC_199 AARYLYALGRENVIPGMRKTIGSTHSTHGSPHVAGFVQTAFATVVVLFFA
MLBr_01974|M.leprae_Br4923 APRLWTALSDGRILP----TRLSSKNRFGVPIVAFGITAFLTLAFPLSLR
.* *:. : * : . .
Mb2347c|M.bovis_AF2122/97 LDSL--ADMVSIGTLTAFSVVAVGVIVLRVR-------------EPDLPR
Rv2320c|M.tuberculosis_H37Rv LDSL--ADMVSIGTLTAFSVVAVGVIVLRVR-------------EPDLPR
MMAR_3621|M.marinum_M LNRL--ADMVSIGTLTAFIVVSVGVIILRVR-------------EPALPR
MUL_1244|M.ulcerans_Agy99 LNRL--ADMVSIGTLTAFIVVSVGVIILRVR-------------EPALPR
MAV_2087|M.avium_104 LQNL--ADMVSIGTLTAFVVVSVGVIVLRVR-------------EPDLPR
TH_0471|M.thermoresistible__bu VGNL--EEMVNIGTLFAFALVSAGVIVLRRT-------------RPDLKR
Mflv_1244|M.gilvum_PYR-GCK FAGM--DPYIHMYTLLAILGTMAILIVQSLCAFSVVAYFHFHKNHPSSAH
Mvan_5564|M.vanbaalenii_PYR-1 AAGM--DPYIHMYTLLAILGTMAILIVQSLCAFSVIAYFHFHKNHPSSAH
MSMEG_0279|M.smegmatis_MC2_155 FAGM--DPYVHMYTLLAILGTMAILIVQSLCAFSVISYFHIHKNHPESKH
MAB_0950c|M.abscessus_ATCC_199 ATGR--DPYTGLYGLMALLGTTAILIVQALTAFAVISYFHVLRHHPETAH
MLBr_01974|M.leprae_Br4923 FDSLNLTGLAVIARFIQFIIVPIALFALARS-----------RTTNSVYV
: : : . ::
Mb2347c|M.bovis_AF2122/97 GFKVPGYPVTPVLSVLACGYILAS-----------------LHWYTWLAF
Rv2320c|M.tuberculosis_H37Rv GFKVPGYPVTPVLSVLACGYILAS-----------------LHWYTWLAF
MMAR_3621|M.marinum_M GFWVPGYPVTPILSILACGYLLYS-----------------LHWYTWIAF
MUL_1244|M.ulcerans_Agy99 GFWVPGYPVTPILSILACGYLLYS-----------------LHWYTWIAF
MAV_2087|M.avium_104 GFRVPGYPVTPVLSIMACGYILAS-----------------LHWYTWIAF
TH_0471|M.thermoresistible__bu GFRVPFVPWLPLAAIAACLWLMLN-----------------LTGLTWVRF
Mflv_1244|M.gilvum_PYR-GCK WFKTFLAPLTGGIGMLYVVYLLWEHKESAAGAASGTLLFKLTPWIVVGVF
Mvan_5564|M.vanbaalenii_PYR-1 WFKTFLAPLLGGIGMLYVVYLLWEHKESAAGAASGTLLFKLTPWIVVGLF
MSMEG_0279|M.smegmatis_MC2_155 WFKTLVAPGLGGLGMLYVVYLLWEHKDTAAGTASGTLLFKLTPWIVVSVF
MAB_0950c|M.abscessus_ATCC_199 WFRTLVAPLLGGLGMVYVVYLLAKHASFAAGTASNDWVFTAIPWVVAAAG
MLBr_01974|M.leprae_Br4923 KRNVFTDKVLPITAVVVSAGLMVS--------------FDYRSIFLTRGG
. .: :: .
Mb2347c|M.bovis_AF2122/97 SGWVAVAVIFYLMWGRHHSALNEEVP---------
Rv2320c|M.tuberculosis_H37Rv SGWVAVAVIFYLMWGRHHSALNEEVP---------
MMAR_3621|M.marinum_M GGWVGIALIFYLFWGRHHSRLNAPALHDNPTGEER
MUL_1244|M.ulcerans_Agy99 GGWVGIALIFYLFWGRHHSRLNAPALHDNPTGEER
MAV_2087|M.avium_104 SGWVLLALIFYFVWGRHHSALNDAAVD--PSGQER
TH_0471|M.thermoresistible__bu LGWMALGLVLYFFYGRHHSMLGRGMTDISARRTG-
Mflv_1244|M.gilvum_PYR-GCK AFGAAMALYFKFKDKRRYELIGRIVYDDSEVRD--
Mvan_5564|M.vanbaalenii_PYR-1 ALGAAMALYFKFNDKRRYELIGRIVYDDSEIRD--
MSMEG_0279|M.smegmatis_MC2_155 VLGAALATYFKLRDPRRYGLIGRIVYDEAVERD--
MAB_0950c|M.abscessus_ATCC_199 IGGIALALTLKYTAPHRYDDLGRTVLEEAHER---
MLBr_01974|M.leprae_Br4923 PNYFSISLIAITFIGIPAVAYLHYYRTSGIK----
:.