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VGHAGELDLHRCIVTGAMTATETCETQSPGVARVVRQRHLGRWLSGGVMVVLVALALRSVATNDRFGWPL VAGYLFDPQILEGVRLTLVLTFVCMAIGIVLGTVLAVMRLSANPVAQALAFAYVGFFRGTPVLVQLIFWF NFAALYPHLSFGIPGVDIDANALISPVLAGVLGLGLHEAAYMAEIIRGGIGSIDVGQIEAARALGLRKNQ VLRRIVLPQAMRVIVPPTGNEVVGMLKTSSLVSVLAVGELLYSAQLIYASNYQTIPLLIVASLWYLVLTA VLSAGQMRLERHFARGSVEIRTAAAEWVRGWLGLGHLARRGVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0177 | - | - | 100% (323) | ABC polar amino acid family protein transporter, inner membrane subunit |
| M. smegmatis MC2 155 | MSMEG_3236 | - | 6e-67 | 47.04% (287) | ABC-type amino acid transport system, permease component |
| M. smegmatis MC2 155 | MSMEG_6594 | - | 7e-58 | 43.42% (281) | amino acid ABC transporter, permease protein, 3-TM region, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0961 | pstA2 | 6e-06 | 28.27% (191) | phosphate ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3582 | - | 2e-67 | 48.36% (275) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0936 | pstA2 | 7e-06 | 28.27% (191) | phosphate ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4238c | - | 3e-66 | 46.13% (271) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 1e-21 | 31.65% (218) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 4e-23 | 33.33% (222) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_2674 | - | 1e-24 | 35.68% (227) | PUTATIVE polar amino acid ABC transporter, inner membrane |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2833 | - | 1e-65 | 46.76% (278) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCINSTGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRFD
MAV_0059|M.avium_104 PNVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFD
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M VGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRIG
MAV_0059|M.avium_104 VGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIG
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0061|M.marinum_M VVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEAA
MAV_0059|M.avium_104 VVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATT
Mb0961|M.bovis_AF2122/97 --------------------------------------------------
Rv0936|M.tuberculosis_H37Rv --------------------------------------------------
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK ----------------------MTNEAGSPPTSGTPQSIDAVPLRHPWR-
Mvan_2833|M.vanbaalenii_PYR-1 ----------------------MT-DVGAPPPSSSPQSIDAIPLKHPWR-
MAB_4238c|M.abscessus_ATCC_199 ----------------------MTSAPAAPPRARVADEAAEPVLRVRRRP
MSMEG_0177|M.smegmatis_MC2_155 ------------MGHAGELDLHRCIVTGAMTATETCETQSPGVARVVRQR
MMAR_0061|M.marinum_M IRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWSQ
MAV_0059|M.avium_104 IQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSN
Mb0961|M.bovis_AF2122/97 ----------------------MGESAESGSRQLPAMSPPRRSVAYRRKI
Rv0936|M.tuberculosis_H37Rv ----------------------MGESAESGSRQLPAMSPPRRSVAYRRKI
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK ----WVAAAV------------------IIVLVGLFLWGAATNDA-----
Mvan_2833|M.vanbaalenii_PYR-1 ----WLAAAA------------------IIVLVGLFLYGAATNPA-----
MAB_4238c|M.abscessus_ATCC_199 RPGNWILSAV------------------ALVFVAMFVHGLVRNPG-----
MSMEG_0177|M.smegmatis_MC2_155 HLGRWLSGGV------------------MVVLVALALRSVATNDR-----
MMAR_0061|M.marinum_M LYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAAHRHKPVGPAAPKSAL
MAV_0059|M.avium_104 LYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQHHKAVGPAAPKSTL
Mb0961|M.bovis_AF2122/97 VDALWWAACVCC----------------LAVVITPTLWMLIGVVSRAVP-
Rv0936|M.tuberculosis_H37Rv VDALWWAACVCC----------------LAVVITPTLWMLIGVVSRAVP-
TH_2674|M.thermoresistible__bu --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK -------YGWSTYAEYLFN--ERILLGVFNTIQLTVYSMVIGIVLGVILT
Mvan_2833|M.vanbaalenii_PYR-1 -------YGWSTFGEYFFH--ERILLGVFNTLQLTIYSMIIGIVLGVFLT
MAB_4238c|M.abscessus_ATCC_199 -------WDWPTFARYFTA--KSVLAALWLTLRLTFYGTVLGFLLGVALA
MSMEG_0177|M.smegmatis_MC2_155 -------FGWPLVAGYLFD--PQILEGVRLTLVLTFVCMAIGIVLGTVLA
MMAR_0061|M.marinum_M TQLRDSFFDWDMYRQAIP---TLFKTGLPNTLILTLSASIIGLALGMALA
MAV_0059|M.avium_104 AQLRDSFFDWDMYRQAIP---TLLRTGLPNTLILTFSASVIGLVLGMVLA
Mb0961|M.bovis_AF2122/97 ------VFHWSVLVQDSQGNGGGLRNAIIGTAVLAIGVILVGGTVSVLTG
Rv0936|M.tuberculosis_H37Rv ------VFHWSVLVQDSQGNGGGLRNAIIGTAVLAIGVILVGGTVSVLTG
TH_2674|M.thermoresistible__bu -------------VQVFSEYSGQIFQAFWTTIQLTVLSAIGALVLGTVLA
. .. * *:. . :.
Mflv_3582|M.gilvum_PYR-GCK IMRLSSNP-VLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLGVPF
Mvan_2833|M.vanbaalenii_PYR-1 VMRLSDNP-VLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLGVPF
MAB_4238c|M.abscessus_ATCC_199 AARLSKNP-VLQAISWTYVWIFRSIPLIVQLLFWFNIAYLYDTIGFGIPF
MSMEG_0177|M.smegmatis_MC2_155 VMRLSANP-VAQALAFAYVGFFRGTPVLVQLIFWFNFAALYPHLSFGIPG
MMAR_0061|M.marinum_M IAGISHQR-WLRWPARVYTDIFRGLPEVVIILIIG----------LGVGP
MAV_0059|M.avium_104 VAGISHAR-WLRWPARVYTDVFRGLPEVVIILLIG----------LGIGP
Mb0961|M.bovis_AF2122/97 IYLSEFATGKTRSILRGAYEVLSGIPSIVLGYVGY---------------
Rv0936|M.tuberculosis_H37Rv IYLSEFATGKTRSILRGAYEVLSGIPSIVLGYVGY---------------
TH_2674|M.thermoresistible__bu AMRLAPVP-VLNWLGAGYVNVVRNTPLTLIILFCAFGLGQTLSITLADRG
.. . * : .
Mflv_3582|M.gilvum_PYR-GCK GPSLLHFDLQDLSFPFALAVIGLALNEAAYMAEIVRAGITSVPEGQLEAS
Mvan_2833|M.vanbaalenii_PYR-1 GPSFFHLDLQDLSIPFVLAVIGLGLNEAAYMAEIVRAGIMSVPEGQMEAS
MAB_4238c|M.abscessus_ATCC_199 GPALFTVDTNELLSGLTAAVIGLTLHQGAYFAEIIRGGILSVDEGQLEAA
MSMEG_0177|M.smegmatis_MC2_155 ----VDIDANALISPVLAGVLGLGLHEAAYMAEIIRGGIGSIDVGQIEAA
MMAR_0061|M.marinum_M -----IVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEAS
MAV_0059|M.avium_104 -----IVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEAS
Mb0961|M.bovis_AF2122/97 ---LALVVYFDWGFSLAAGVLVLSVMSIPYIAKATESALAQVPTSYREAA
Rv0936|M.tuberculosis_H37Rv ---LALVVYFDWGFSLAAGVLVLSVMSIPYIAKATESALAQVPTSYREAA
TH_2674|M.thermoresistible__bu ------SPTFLQDSNFRLAVLGFTVYTAAFVCETIRAGVNTVPVGQVEAA
.: : : .:. : ...: : . **:
Mflv_3582|M.gilvum_PYR-GCK TALGMSWGRAMRRTVLPQAMRVIIP-PTGNEVISLLKTTSLVTAVPYAFD
Mvan_2833|M.vanbaalenii_PYR-1 TALGMSWGKAMRRTVLPQAMRVIIP-PTGNELISLLKTTSLVTAVPYAFD
MAB_4238c|M.abscessus_ATCC_199 AALGIPRRRQFFRIVLPQAMRSVMP-NAANEVISLVKGTSIVSTMAIADL
MSMEG_0177|M.smegmatis_MC2_155 RALGLRKNQVLRRIVLPQAMRVIVP-PTGNEVVGMLKTSSLVSVLAVGEL
MMAR_0061|M.marinum_M RALGFSYSAAMRLVVVPQGVRRVLP-ALVNQFIALLKASALVYFLGLIAQ
MAV_0059|M.avium_104 RALGFSYATAMRLVVVPQGVRRVLP-ALVNQFIALLKASALVYFLGLVAD
Mb0961|M.bovis_AF2122/97 EALGLPAGWALRKIVLKTAMPGIVTGMLVALALAIGETAPLLYTAGWSNS
Rv0936|M.tuberculosis_H37Rv EALGLPAGWALRKIVLKTAMPGIVTGMLVALALAIGETAPLLYTAGWSNS
TH_2674|M.thermoresistible__bu RALGFTFGQNLRIIVLPQAFRAVII-PLGTVLIALTKNTTIASAIGVAEA
***: : *: .. :: :.: : :.:
Mflv_3582|M.gilvum_PYR-GCK LYSIATR-EIAARIFEPVPLLLVAA---TWYLVITSILMVGQFYLERYFS
Mvan_2833|M.vanbaalenii_PYR-1 VYSIATR-EIAARIFEPVPLLLVAA---AWYLVITSILMVGQFYLERYFS
MAB_4238c|M.abscessus_ATCC_199 FYQVQV---IFGRNGRVVPLLMVAT---AWYIVITSVLTVVQYYIERHYA
MSMEG_0177|M.smegmatis_MC2_155 LYSAQL---IYASNYQTIPLLIVAS---LWYLVLTAVLSAGQMRLERHFA
MMAR_0061|M.marinum_M QRELFQVGRDLNAQTGNLSPLVAAG---IFYLMLTVPLTHLVNYIDARLR
MAV_0059|M.avium_104 QRELFQVGRDLNAETGNLSPLVAAG---ACYLILTVPLTHLVNMIDARLR
Mb0961|M.bovis_AF2122/97 PPTGQLTDSPVGYLTYPIWTFYNQPSKSAQDLSYDAALLLIVFLLLLIFI
Rv0936|M.tuberculosis_H37Rv PPTGQLTDSPVGYLTYPIWTFYNQPSKSAQDLSYDAALLLIVFLLLLIFI
TH_2674|M.thermoresistible__bu ALLMKEM------IENTSAVLIVGAIFAVGFLILTLPLGLLSGRLSNRLA
: : * :
Mflv_3582|M.gilvum_PYR-GCK RGVSRQLTSKQLEALAKAQLGSAVP----
Mvan_2833|M.vanbaalenii_PYR-1 RGASRKLTSKQLEALALAQLPQVK-----
MAB_4238c|M.abscessus_ATCC_199 RGAHR------------------------
MSMEG_0177|M.smegmatis_MC2_155 RGSVEIRTAAAEWVRGWLGLGHLARRGVR
MMAR_0061|M.marinum_M RGRRRLDPEDPPGVVSSTIGEEMT-----
MAV_0059|M.avium_104 RGRAAVDPEEPAEMLT--FGQEIT-----
Mb0961|M.bovis_AF2122/97 GRLINWLSRRRWDV---------------
Rv0936|M.tuberculosis_H37Rv GRLINWLSRRRWDV---------------
TH_2674|M.thermoresistible__bu VRR--------------------------