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TSAPAAPPRARVADEAAEPVLRVRRRPRPGNWILSAVALVFVAMFVHGLVRNPGWDWPTFARYFTAKSVL AALWLTLRLTFYGTVLGFLLGVALAAARLSKNPVLQAISWTYVWIFRSIPLIVQLLFWFNIAYLYDTIGF GIPFGPALFTVDTNELLSGLTAAVIGLTLHQGAYFAEIIRGGILSVDEGQLEAAAALGIPRRRQFFRIVL PQAMRSVMPNAANEVISLVKGTSIVSTMAIADLFYQVQVIFGRNGRVVPLLMVATAWYIVITSVLTVVQY YIERHYARGAHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4238c | - | - | 100% (293) | amino acid ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_0277c | - | 2e-26 | 31.98% (222) | amino acid ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_3052 | - | 5e-24 | 34.25% (219) | putative glutamate ABC transporter, permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3582 | - | 4e-65 | 43.05% (295) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0061 | glnQ | 3e-22 | 31.58% (247) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 3e-21 | 31.15% (244) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_0177 | - | 3e-66 | 46.13% (271) | ABC polar amino acid family protein transporter, inner membrane |
| M. thermoresistible (build 8) | TH_0515 | - | 6e-22 | 29.83% (295) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2833 | - | 2e-67 | 43.73% (295) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
TH_0515|M.thermoresistible__bu --VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQSASPL
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
TH_0515|M.thermoresistible__bu PTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGTLSDAP
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCINSTGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRFD
MAV_0059|M.avium_104 PNVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFD
TH_0515|M.thermoresistible__bu PSICINSLGEFTGFDNELLRAIAAKLGLQISFVGTEFSALLAQVASGRFD
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRIG
MAV_0059|M.avium_104 VGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIG
TH_0515|M.thermoresistible__bu VGSSSITTTEQRRRTVEFTNGYDFGYFSLVVPSGSAITGFGDLVPGQRIG
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0177|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEAA
MAV_0059|M.avium_104 VVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATT
TH_0515|M.thermoresistible__bu VVQGTVQESYVVDTLGLRPVIFPDYNTVYASLKTRQIDAWVAPSQQAEGT
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------MTNEAGSPPTSG
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------MT-DVGAPPPSS
MSMEG_0177|M.smegmatis_MC2_155 -------------------------MGHAGELDLHRCIVTGAMTATETCE
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------MTSAPAAPPRAR
MMAR_0061|M.marinum_M IRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWSQ
MAV_0059|M.avium_104 IQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSN
TH_0515|M.thermoresistible__bu VRPGDPAEIIENTFSLDNFIAYAVAPGNQPLIDALNAGLDAVIADGTWAR
: .
Mflv_3582|M.gilvum_PYR-GCK T--PQSIDAVPLR---HPWRWVAAAVIIVLVGLFLWG-------------
Mvan_2833|M.vanbaalenii_PYR-1 S--PQSIDAIPLK---HPWRWLAAAAIIVLVGLFLYG-------------
MSMEG_0177|M.smegmatis_MC2_155 TQSPGVARVVRQR---HLGRWLSGGVMVVLVALALRS-------------
MAB_4238c|M.abscessus_ATCC_199 VADEAAEPVLRVRRRPRPGNWILSAVALVFVAMFVHG-------------
MMAR_0061|M.marinum_M LYSKWVPRTLPPG--WKPGSRAVAAPTLPDFAAIAAA--HRHKPVGPAAP
MAV_0059|M.avium_104 LYSQWVPRTLPPG--WKPGSQAVAPPKLPDFAAIAAS--QHHKAVGPAAP
TH_0515|M.thermoresistible__bu LYSEWVPRALPPG--WKPGSKAAPPPQLPDFDAIAAERASQQPAAGPGVR
.: : : .
Mflv_3582|M.gilvum_PYR-GCK -----AATNDAYGWSTYAEYLFNERILLGVFNTIQLTVYSMVIGIVLGVI
Mvan_2833|M.vanbaalenii_PYR-1 -----AATNPAYGWSTFGEYFFHERILLGVFNTLQLTIYSMIIGIVLGVF
MSMEG_0177|M.smegmatis_MC2_155 -----VATNDRFGWPLVAGYLFDPQILEGVRLTLVLTFVCMAIGIVLGTV
MAB_4238c|M.abscessus_ATCC_199 -----LVRNPGWDWPTFARYFTAKSVLAALWLTLRLTFYGTVLGFLLGVA
MMAR_0061|M.marinum_M KSALTQLRDSFFDWDMYRQAIP-TLFKTGLPNTLILTLSASIIGLALGMA
MAV_0059|M.avium_104 KSTLAQLRDSFFDWDMYRQAIP-TLLRTGLPNTLILTFSASVIGLVLGMV
TH_0515|M.thermoresistible__bu KSTLAQLADSFLDWELYRQAIP-DLLTTGLPNTLLLTVGAGVIGLVLGMV
: .* : . .: *: **. :*: **
Mflv_3582|M.gilvum_PYR-GCK LTIMRLSSNPVLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLGVP
Mvan_2833|M.vanbaalenii_PYR-1 LTVMRLSDNPVLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLGVP
MSMEG_0177|M.smegmatis_MC2_155 LAVMRLSANPVAQALAFAYVGFFRGTPVLVQLIFWFNFAALYPHLSFGIP
MAB_4238c|M.abscessus_ATCC_199 LAAARLSKNPVLQAISWTYVWIFRSIPLIVQLLFWFNIAYLYDTIGFGIP
MMAR_0061|M.marinum_M LAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIG--------LGVGPI
MAV_0059|M.avium_104 LAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIG--------LGIGPI
TH_0515|M.thermoresistible__bu LAIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIG--------LGLGPV
*: :* : .: .**. * * : : : .*
Mflv_3582|M.gilvum_PYR-GCK FGPSLLHFDLQDLSFPFALAVIGLALNEAAYMAEIVRAGITSVPEGQLEA
Mvan_2833|M.vanbaalenii_PYR-1 FGPSFFHLDLQDLSIPFVLAVIGLGLNEAAYMAEIVRAGIMSVPEGQMEA
MSMEG_0177|M.smegmatis_MC2_155 G----VDIDANALISPVLAGVLGLGLHEAAYMAEIIRGGIGSIDVGQIEA
MAB_4238c|M.abscessus_ATCC_199 FGPALFTVDTNELLSGLTAAVIGLTLHQGAYFAEIIRGGILSVDEGQLEA
MMAR_0061|M.marinum_M VG-------GLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEA
MAV_0059|M.avium_104 VG-------GLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEA
TH_0515|M.thermoresistible__bu VG-------GLTGYNPFPLGILALGLMAAAYVGEILRSGIQSVEPGQLEA
.: .* : .**..**:*.** *: **:**
Mflv_3582|M.gilvum_PYR-GCK STALGMSWGRAMRRTVLPQAMRVIIPPTGNEVISLLKTTSLVTAVPYAFD
Mvan_2833|M.vanbaalenii_PYR-1 STALGMSWGKAMRRTVLPQAMRVIIPPTGNELISLLKTTSLVTAVPYAFD
MSMEG_0177|M.smegmatis_MC2_155 ARALGLRKNQVLRRIVLPQAMRVIVPPTGNEVVGMLKTSSLVSVLAVGEL
MAB_4238c|M.abscessus_ATCC_199 AAALGIPRRRQFFRIVLPQAMRSVMPNAANEVISLVKGTSIVSTMAIADL
MMAR_0061|M.marinum_M SRALGFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQ
MAV_0059|M.avium_104 SRALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVAD
TH_0515|M.thermoresistible__bu ARALGFSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLVAD
: ***: : *:**.:* ::* *:.:.::* :::* :
Mflv_3582|M.gilvum_PYR-GCK LYSIATREIAARIFE-PVPLLLVAATWYLVITSILMVGQFYLERYFSRGV
Mvan_2833|M.vanbaalenii_PYR-1 VYSIATREIAARIFE-PVPLLLVAAAWYLVITSILMVGQFYLERYFSRGA
MSMEG_0177|M.smegmatis_MC2_155 LYS--AQLIYASNYQ-TIPLLIVASLWYLVLTAVLSAGQMRLERHFARGS
MAB_4238c|M.abscessus_ATCC_199 FYQ--VQVIFGRNGR-VVPLLMVATAWYIVITSVLTVVQYYIERHYARGA
MMAR_0061|M.marinum_M QRELFQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGR
MAV_0059|M.avium_104 QRELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRGR
TH_0515|M.thermoresistible__bu QRELFQVGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDNRLRRGR
. :. *:.* *: :* * :: **
Mflv_3582|M.gilvum_PYR-GCK SRQLTSKQLEALAKAQLGSAVP----
Mvan_2833|M.vanbaalenii_PYR-1 SRKLTSKQLEALALAQLPQVK-----
MSMEG_0177|M.smegmatis_MC2_155 VEIRTAAAEWVRGWLGLGHLARRGVR
MAB_4238c|M.abscessus_ATCC_199 HR------------------------
MMAR_0061|M.marinum_M RRLDPEDPPGVVSSTIGEEMT-----
MAV_0059|M.avium_104 AAVDPEEPAEMLT--FGQEIT-----
TH_0515|M.thermoresistible__bu K-PAAEDPLEPAT---AQEMI-----