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MTDVGAPPPSSSPQSIDAIPLKHPWRWLAAAAIIVLVGLFLYGAATNPAYGWSTFGEYFFHERILLGVFN TLQLTIYSMIIGIVLGVFLTVMRLSDNPVLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLGVPFG PSFFHLDLQDLSIPFVLAVIGLGLNEAAYMAEIVRAGIMSVPEGQMEASTALGMSWGKAMRRTVLPQAMR VIIPPTGNELISLLKTTSLVTAVPYAFDVYSIATREIAARIFEPVPLLLVAAAWYLVITSILMVGQFYLE RYFSRGASRKLTSKQLEALALAQLPQVK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2833 | - | - | 100% (308) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_5576 | - | 2e-30 | 37.67% (215) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_0292 | - | 3e-28 | 32.75% (229) | polar amino acid ABC transporter, inner membrane subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3582 | - | 1e-153 | 87.09% (302) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4238c | - | 1e-67 | 43.73% (295) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 8e-23 | 35.40% (226) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 2e-23 | 36.10% (205) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_3236 | - | 1e-138 | 78.62% (304) | ABC-type amino acid transport system, permease component |
| M. thermoresistible (build 8) | TH_0515 | - | 4e-25 | 36.04% (222) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
TH_0515|M.thermoresistible__bu --VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQSASPL
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
TH_0515|M.thermoresistible__bu PTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGTLSDAP
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCINSTGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRFD
MAV_0059|M.avium_104 PNVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFD
TH_0515|M.thermoresistible__bu PSICINSLGEFTGFDNELLRAIAAKLGLQISFVGTEFSALLAQVASGRFD
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRIG
MAV_0059|M.avium_104 VGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIG
TH_0515|M.thermoresistible__bu VGSSSITTTEQRRRTVEFTNGYDFGYFSLVVPSGSAITGFGDLVPGQRIG
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEAA
MAV_0059|M.avium_104 VVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATT
TH_0515|M.thermoresistible__bu VVQGTVQESYVVDTLGLRPVIFPDYNTVYASLKTRQIDAWVAPSQQAEGT
Mvan_2833|M.vanbaalenii_PYR-1 ----------------------MT-DVGAPPPSSSPQSIDAIPLKHPWR-
Mflv_3582|M.gilvum_PYR-GCK ----------------------MTNEAGSPPTSGTPQSIDAVPLRHPWR-
MSMEG_3236|M.smegmatis_MC2_155 ----------------------MT-DVDTPP-QAAPAAIDAVPLRHPWR-
MAB_4238c|M.abscessus_ATCC_199 ----------------------MTSAPAAPPRARVADEAAEPVLRVRRRP
MMAR_0061|M.marinum_M IRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWSQ
MAV_0059|M.avium_104 IQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSN
TH_0515|M.thermoresistible__bu VRPGDPAEIIENTFSLDNFIAYAVAPGNQPLIDALNAGLDAVIADGTWAR
. *
Mvan_2833|M.vanbaalenii_PYR-1 ----WLAAAAIIVLVG--------------------------------LF
Mflv_3582|M.gilvum_PYR-GCK ----WVAAAVIIVLVG--------------------------------LF
MSMEG_3236|M.smegmatis_MC2_155 ----WVAAVVIVILAA--------------------------------LF
MAB_4238c|M.abscessus_ATCC_199 RPGNWILSAVALVFVA--------------------------------MF
MMAR_0061|M.marinum_M LYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAA--HRHKPVGPAAPKS
MAV_0059|M.avium_104 LYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAAS--QHHKAVGPAAPKS
TH_0515|M.thermoresistible__bu LYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAERASQQPAAGPGVRKS
*: .
Mvan_2833|M.vanbaalenii_PYR-1 LYGAATNPAYGWSTFGEYFFHERIL-LGVFNTLQLTIYSMIIGIVLGVFL
Mflv_3582|M.gilvum_PYR-GCK LWGAATNDAYGWSTYAEYLFNERIL-LGVFNTIQLTVYSMVIGIVLGVIL
MSMEG_3236|M.smegmatis_MC2_155 LYGAATNDSYRWPIYFEYLFNERVLTVGVLNTLQLTIYSMLIAIVLGVLL
MAB_4238c|M.abscessus_ATCC_199 VHGLVRNPGWDWPTFARYFTAKSVL-AALWLTLRLTFYGTVLGFLLGVAL
MMAR_0061|M.marinum_M ALTQLRDSFFDWDMYRQAIP--TLFKTGLPNTLILTLSASIIGLALGMAL
MAV_0059|M.avium_104 TLAQLRDSFFDWDMYRQAIP--TLLRTGLPNTLILTFSASVIGLVLGMVL
TH_0515|M.thermoresistible__bu TLAQLADSFLDWELYRQAIP--DLLTTGLPNTLLLTVGAGVIGLVLGMVL
: * : . : :: .: *: **. . ::.: **: *
Mvan_2833|M.vanbaalenii_PYR-1 TVMRLSDNPVLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLGVPF
Mflv_3582|M.gilvum_PYR-GCK TIMRLSSNPVLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLGVPF
MSMEG_3236|M.smegmatis_MC2_155 AVMRLSPNPVFRSVAWVYLWIFRGTPVYVQLVFWGLLPTIYQNIQLGVPF
MAB_4238c|M.abscessus_ATCC_199 AAARLSKNPVLQAISWTYVWIFRSIPLIVQLLFWFNIAYLYDTIGFGIPF
MMAR_0061|M.marinum_M AIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLG------------V
MAV_0059|M.avium_104 AVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLG------------I
TH_0515|M.thermoresistible__bu AIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIGLG------------L
: :* : : .: :**. * * : : .
Mvan_2833|M.vanbaalenii_PYR-1 GPSFFHLDLQDLSIPFVLAVIGLGLNEAAYMAEIVRAGIMSVPEGQMEAS
Mflv_3582|M.gilvum_PYR-GCK GPSLLHFDLQDLSFPFALAVIGLALNEAAYMAEIVRAGITSVPEGQLEAS
MSMEG_3236|M.smegmatis_MC2_155 GPSFFHLNLQSLSIPFLLAILGLALNEAAYMAEIIRAGISSVPEGQMEAS
MAB_4238c|M.abscessus_ATCC_199 GPALFTVDTNELLSGLTAAVIGLTLHQGAYFAEIIRGGILSVDEGQLEAA
MMAR_0061|M.marinum_M GPIVGGLTNNN---PYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEAS
MAV_0059|M.avium_104 GPIVGGLTNNN---PYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEAS
TH_0515|M.thermoresistible__bu GPVVGGLTGYN---PFPLGILALGLMAAAYVGEILRSGIQSVEPGQLEAA
** . . . .: .* : .**..**:*.** ** **:**:
Mvan_2833|M.vanbaalenii_PYR-1 TALGMSWGKAMRRTVLPQAMRVIIPPTGNELISLLKTTSLVTAVPYAFDV
Mflv_3582|M.gilvum_PYR-GCK TALGMSWGRAMRRTVLPQAMRVIIPPTGNEVISLLKTTSLVTAVPYAFDL
MSMEG_3236|M.smegmatis_MC2_155 TALGMSWGLAMRRTVLPQAMRVIIPPTGNEIISMLKTTSLVTAVPFTLDL
MAB_4238c|M.abscessus_ATCC_199 AALGIPRRRQFFRIVLPQAMRSVMPNAANEVISLVKGTSIVSTMAIADLF
MMAR_0061|M.marinum_M RALGFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQQ
MAV_0059|M.avium_104 RALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVADQ
TH_0515|M.thermoresistible__bu RALGFSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLVADQ
***:. : *:**.:* ::* *:.*:::* :::* :
Mvan_2833|M.vanbaalenii_PYR-1 YSIATREIAARIFE-PVPLLLVAAAWYLVITSILMVGQFYLERYFSRGAS
Mflv_3582|M.gilvum_PYR-GCK YSIATREIAARIFE-PVPLLLVAATWYLVITSILMVGQFYLERYFSRGVS
MSMEG_3236|M.smegmatis_MC2_155 YGITSREIAARIFE-PVPLLLVAATWYLVITSILMVGQYYLERYYSRGAS
MAB_4238c|M.abscessus_ATCC_199 YQVQV--IFGRNGR-VVPLLMVATAWYIVITSVLTVVQYYIERHYARGAH
MMAR_0061|M.marinum_M RELFQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRR
MAV_0059|M.avium_104 RELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRGRA
TH_0515|M.thermoresistible__bu RELFQVGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDNRLRRGRK
: . :. *:.* *: :* * :: **
Mvan_2833|M.vanbaalenii_PYR-1 RKLTSKQLEALALAQ-LPQVK-
Mflv_3582|M.gilvum_PYR-GCK RQLTSKQLEALAKAQ-LGSAVP
MSMEG_3236|M.smegmatis_MC2_155 RKLTTKQLEALAKAQTVGEAHP
MAB_4238c|M.abscessus_ATCC_199 R---------------------
MMAR_0061|M.marinum_M RLDPEDPPGVVSSTIGEEMT--
MAV_0059|M.avium_104 AVDPEEPAEMLT--FGQEIT--
TH_0515|M.thermoresistible__bu -PAAEDPLEPAT---AQEMI--