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TNEAGSPPTSGTPQSIDAVPLRHPWRWVAAAVIIVLVGLFLWGAATNDAYGWSTYAEYLFNERILLGVFN TIQLTVYSMVIGIVLGVILTIMRLSSNPVLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLGVPFG PSLLHFDLQDLSFPFALAVIGLALNEAAYMAEIVRAGITSVPEGQLEASTALGMSWGRAMRRTVLPQAMR VIIPPTGNEVISLLKTTSLVTAVPYAFDLYSIATREIAARIFEPVPLLLVAATWYLVITSILMVGQFYLE RYFSRGVSRQLTSKQLEALAKAQLGSAVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3582 | - | - | 100% (310) | polar amino acid ABC transporter, inner membrane subunit |
| M. gilvum PYR-GCK | Mflv_1232 | - | 7e-31 | 38.36% (219) | polar amino acid ABC transporter, inner membrane subunit |
| M. gilvum PYR-GCK | Mflv_0858 | - | 1e-24 | 33.73% (255) | polar amino acid ABC transporter, inner membrane subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2835c | ugpA | 4e-06 | 26.36% (220) | sn-glycerol-3-phosphate transport integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4238c | - | 4e-65 | 43.05% (295) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 7e-22 | 34.96% (226) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 1e-22 | 33.18% (223) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_3236 | - | 1e-139 | 78.95% (304) | ABC-type amino acid transport system, permease component |
| M. thermoresistible (build 8) | TH_0515 | - | 1e-25 | 36.55% (238) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2833 | - | 1e-153 | 87.09% (302) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
TH_0515|M.thermoresistible__bu --VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQSASPL
Rv2835c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
TH_0515|M.thermoresistible__bu PTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGTLSDAP
Rv2835c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCINSTGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRFD
MAV_0059|M.avium_104 PNVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFD
TH_0515|M.thermoresistible__bu PSICINSLGEFTGFDNELLRAIAAKLGLQISFVGTEFSALLAQVASGRFD
Rv2835c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRIG
MAV_0059|M.avium_104 VGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIG
TH_0515|M.thermoresistible__bu VGSSSITTTEQRRRTVEFTNGYDFGYFSLVVPSGSAITGFGDLVPGQRIG
Rv2835c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3236|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4238c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M VVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEAA
MAV_0059|M.avium_104 VVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATT
TH_0515|M.thermoresistible__bu VVQGTVQESYVVDTLGLRPVIFPDYNTVYASLKTRQIDAWVAPSQQAEGT
Rv2835c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3582|M.gilvum_PYR-GCK ----------------------MTNEAGSPPTSGTPQSIDAVPLRHPWR-
Mvan_2833|M.vanbaalenii_PYR-1 ----------------------MT-DVGAPPPSSSPQSIDAIPLKHPWR-
MSMEG_3236|M.smegmatis_MC2_155 ----------------------MT-DVDTPP-QAAPAAIDAVPLRHPWR-
MAB_4238c|M.abscessus_ATCC_199 ----------------------MTSAPAAPPRARVADEAAEPVLRVRRRP
MMAR_0061|M.marinum_M IRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWSQ
MAV_0059|M.avium_104 IQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSN
TH_0515|M.thermoresistible__bu VRPGDPAEIIENTFSLDNFIAYAVAPGNQPLIDALNAGLDAVIADGTWAR
Rv2835c|M.tuberculosis_H37Rv --------------------------MAAPQRARLRSSKERVRDYALFVV
*
Mflv_3582|M.gilvum_PYR-GCK ----WVAAAVIIVLVG--------------------------------LF
Mvan_2833|M.vanbaalenii_PYR-1 ----WLAAAAIIVLVG--------------------------------LF
MSMEG_3236|M.smegmatis_MC2_155 ----WVAAVVIVILAA--------------------------------LF
MAB_4238c|M.abscessus_ATCC_199 RPGNWILSAVALVFVA--------------------------------MF
MMAR_0061|M.marinum_M LYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAA--HRHKPVGPAAPKS
MAV_0059|M.avium_104 LYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAAS--QHHKAVGPAAPKS
TH_0515|M.thermoresistible__bu LYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAERASQQPAAGPGVRKS
Rv2835c|M.tuberculosis_H37Rv LVGPNVALLLLFVYRPLADN----------------------IRLSFFDW
:
Mflv_3582|M.gilvum_PYR-GCK LWGAATNDAYGWSTYAEYLFN---ERIL-LGVFNTIQLTVYSMVIGIVLG
Mvan_2833|M.vanbaalenii_PYR-1 LYGAATNPAYGWSTFGEYFFH---ERIL-LGVFNTLQLTIYSMIIGIVLG
MSMEG_3236|M.smegmatis_MC2_155 LYGAATNDSYRWPIYFEYLFN---ERVLTVGVLNTLQLTIYSMLIAIVLG
MAB_4238c|M.abscessus_ATCC_199 VHGLVRNPGWDWPTFARYFTA---KSVL-AALWLTLRLTFYGTVLGFLLG
MMAR_0061|M.marinum_M ALTQLRDSFFDWDMYRQAIP-----TLFKTGLPNTLILTLSASIIGLALG
MAV_0059|M.avium_104 TLAQLRDSFFDWDMYRQAIP-----TLLRTGLPNTLILTFSASVIGLVLG
TH_0515|M.thermoresistible__bu TLAQLADSFLDWELYRQAIP-----DLLTTGLPNTLLLTVGAGVIGLVLG
Rv2835c|M.tuberculosis_H37Rv NVSDPSARFVGLSNYTEWFTRSDTRQIVFNTAVFTGAAVVGSMVLGLALA
: . : :. * .. . ::.: *.
Mflv_3582|M.gilvum_PYR-GCK VILTIMRLSSNPVLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLG
Mvan_2833|M.vanbaalenii_PYR-1 VFLTVMRLSDNPVLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLG
MSMEG_3236|M.smegmatis_MC2_155 VLLAVMRLSPNPVFRSVAWVYLWIFRGTPVYVQLVFWGLLPTIYQNIQLG
MAB_4238c|M.abscessus_ATCC_199 VALAAARLSKNPVLQAISWTYVWIFRSIPLIVQLLFWFNIAYLYDTIGFG
MMAR_0061|M.marinum_M MALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLG----------
MAV_0059|M.avium_104 MVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLG----------
TH_0515|M.thermoresistible__bu MVLAIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIGLG----------
Rv2835c|M.tuberculosis_H37Rv MLLDRPLRGRNLVRSTVFAPFVISGAAVGLAAQFVFDPHFGLIQDLLR--
: * . : . . : :
Mflv_3582|M.gilvum_PYR-GCK VPFGPSLLHFDLQDLSFPFALAVIGLALNEAAYMAEIVRAGITSVPEGQL
Mvan_2833|M.vanbaalenii_PYR-1 VPFGPSFFHLDLQDLSIPFVLAVIGLGLNEAAYMAEIVRAGIMSVPEGQM
MSMEG_3236|M.smegmatis_MC2_155 VPFGPSFFHLNLQSLSIPFLLAILGLALNEAAYMAEIIRAGISSVPEGQM
MAB_4238c|M.abscessus_ATCC_199 IPFGPALFTVDTNELLSGLTAAVIGLTLHQGAYFAEIIRGGILSVDEGQL
MMAR_0061|M.marinum_M --VGPIVGGLTNNN---PYPLGIAALGLMAGAYVGEILRSGIQSVDPGQL
MAV_0059|M.avium_104 --IGPIVGGLTNNN---PYPLGIAALGMMAAAYIGEILRSGIQSVDPGQL
TH_0515|M.thermoresistible__bu --LGPVVGGLTGYN---PFPLGILALGLMAAAYVGEILRSGIQSVEPGQL
Rv2835c|M.tuberculosis_H37Rv -RIGVGVPDFYQDAR-WALFMVTITYVWKNLGYTFVIYLAALQGVRRDLL
.* . . .* * ..: .* . :
Mflv_3582|M.gilvum_PYR-GCK EASTALGMSWGRAMRRTVLPQAMRVIIPPTGNEVISLLKTTSLVTAVPYA
Mvan_2833|M.vanbaalenii_PYR-1 EASTALGMSWGKAMRRTVLPQAMRVIIPPTGNELISLLKTTSLVTAVPYA
MSMEG_3236|M.smegmatis_MC2_155 EASTALGMSWGLAMRRTVLPQAMRVIIPPTGNEIISMLKTTSLVTAVPFT
MAB_4238c|M.abscessus_ATCC_199 EAAAALGIPRRRQFFRIVLPQAMRSVMPNAANEVISLVKGTSIVSTMAIA
MMAR_0061|M.marinum_M EASRALGFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLI
MAV_0059|M.avium_104 EASRALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLV
TH_0515|M.thermoresistible__bu EAARALGFSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLV
Rv2835c|M.tuberculosis_H37Rv EAAEIDGASRWAVFRRVLLPQLRPTTFFLSITVLINSLQVFDVINVMTRG
**: * . : ::** : . .* :: :: :
Mflv_3582|M.gilvum_PYR-GCK FDL-YSIATREIAARIFE-PVPLLLVAATWYLVITSILMVGQFYLERYFS
Mvan_2833|M.vanbaalenii_PYR-1 FDV-YSIATREIAARIFE-PVPLLLVAAAWYLVITSILMVGQFYLERYFS
MSMEG_3236|M.smegmatis_MC2_155 LDL-YGITSREIAARIFE-PVPLLLVAATWYLVITSILMVGQYYLERYYS
MAB_4238c|M.abscessus_ATCC_199 DLF-YQVQV--IFGRNGR-VVPLLMVATAWYIVITSVLTVVQYYIERHYA
MMAR_0061|M.marinum_M AQQ-RELFQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLR
MAV_0059|M.avium_104 ADQ-RELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLR
TH_0515|M.thermoresistible__bu ADQ-RELFQVGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDNRLR
Rv2835c|M.tuberculosis_H37Rv GPEGTGTTTMVYQVYVETFRNFRAGYGATVATIMFLVLLAVTYYQVRVMD
. : *
Mflv_3582|M.gilvum_PYR-GCK RGVSRQLTSKQLEALAKAQ-LGSAVP
Mvan_2833|M.vanbaalenii_PYR-1 RGASRKLTSKQLEALALAQ-LPQVK-
MSMEG_3236|M.smegmatis_MC2_155 RGASRKLTTKQLEALAKAQTVGEAHP
MAB_4238c|M.abscessus_ATCC_199 RGAHR---------------------
MMAR_0061|M.marinum_M RGRRRLDPEDPPGVVSSTIGEEMT--
MAV_0059|M.avium_104 RGRAAVDPEEPAEMLT--FGQEIT--
TH_0515|M.thermoresistible__bu RGRK-PAAEDPLEPAT---AQEMI--
Rv2835c|M.tuberculosis_H37Rv RGQRQ---------------------
**