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MSFVVVSAQELESAAALLAGVGSNVGAAGSAAAGPTAAVLGALGADEVSAAVAELFGDHAQAYQVVSAQA AAFHQRFVVALAAAAGSYGRAESAGAAVLQTVGADVLGAVNAPTMAVLGRPLIGDGVDAAAGSGHNGGAG GLLWGNGGDGGAGAAGQAGGRGGDAGLIGTGGAGGAGGAGGAGGNGGAGGAGGRGGLVFGGGGAGGAGGD GGTATIGAQGLAGQTGQTGHTGGAGGDGGAGGRGGWLWSAGGDGGAGGLGGTGGAGGAGGTGIAATTAGG IGQAGGDGGAGGAGGAGGNGGAGGATGWFGSTGMTGAGGAGGHGGNGAIAGNGGAGANGDMTHLDGGNGG NGGNPGLGGAGGNGGAGSHAGAHGLAGSSPTTNAGHGGKGGDGYTSTDPGTDGGNGGHGGAGGYYGNGGA GGNGGNGATGNLGAAPLAEGEPGGDGGAGGNGGTGGAGGAGGVISGDGGAGGRGGGGGNGGNGAAGANGT NATISGTNGGNAGAGGNGGNGGTGGNGGAGGAATHGSAGANGAGGAGGNGGDGAIAGDGGTGANGDATHF DGGNGGNGANPGIGGLGGAGGTSGDGTTPAAHGTNGTTPTTTNGSGGRGGDGYTSTDPTLNGGKGGTGGN GGDYGNGGAGGNGGNGATGTTGTNPTPHPITSHANPGTDGTTSNGGNGTTGSDGTAAGQQGGTGGAGYNS GGPGDTNPFGGNGGTGGMGGPGTQGGAGGSGGYGPLVGGWGGDGGAGGDGGGAGGDGGTGGASSGANGFT GQAGNGGNGGIGGNGGGSGGNGGDGGDANYAIPWGNSAYAGDGGYGGDGGTGATGGTGSDGGAGGAGGAG GLYGNGGNGGTGGTGGDGGTGATGGTGGTGGNGGDSTGNSLSSLPGNGGDGGDGGTGGTGGTGGSGGDGG AAGAGGTYGQSGTNGTGGAAGSGGEGGAGGTGGDGGSGGVTYDSDYNPGPPYGTSGQSGATGATGATGQA GMAGTTPGTGTPGPGGDGGDGTGGNGGNGGPGFP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5341 | - | - | 100% (1014) | PE-PGRS family protein |
| M. marinum M | MMAR_5308 | - | 0.0 | 69.86% (1105) | PE-PGRS family protein |
| M. marinum M | MMAR_5307 | - | 0.0 | 69.30% (1101) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 49.34% (1141) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-166 | 46.75% (785) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 0.0 | 51.68% (1072) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 3e-09 | 33.76% (157) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-47 | 33.33% (441) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-21 | 39.57% (187) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-164 | 40.28% (1085) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-51 | 43.14% (306) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 47.82% (1100) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-167 | 44.50% (854) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5341|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 -----------------------------------------MSLVIVAPE
Rv1450c|M.tuberculosis_H37Rv -----------------------------------------MSLVIVAPE
MMAR_5341|M.marinum_M -----------------------------------------MSFVVVSAQ
MUL_4367|M.ulcerans_Agy99 -----------------------------------------MSFVSVGPG
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------MMFLAP
Mb1485c|M.bovis_AF2122/97 TVAAAALDVARIGSSIGVANSAAAGSTTSVL-AAGADEVSAAIATLFGSH
Rv1450c|M.tuberculosis_H37Rv TVAAAALDVARIGSSIGAANAAAAGSTTSVL-AAGADEVSAAIATLFGSH
MMAR_5341|M.marinum_M ELESAAALLAGVGSNVGAAGSAAAGPTAAVLGALGADEVSAAVAELFGDH
MUL_4367|M.ulcerans_Agy99 LLEAAARDLAGLGAGLREANLAAAGATVGVL-PAAGDEVSAAIAELFGGF
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPV
Mflv_5091|M.gilvum_PYR-GCK -------------------------MVTFGGGATPTPTSLGAAAVDLSG-
Mvan_1264|M.vanbaalenii_PYR-1 PGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASLVDLSG-
Mb1485c|M.bovis_AF2122/97 AREYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLN-
Rv1450c|M.tuberculosis_H37Rv AREYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLN-
MMAR_5341|M.marinum_M AQAYQVVSAQAAAFHQRFVVALAAAAGSYGRAESAGAAVLQTVGADVLG-
MUL_4367|M.ulcerans_Agy99 GREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALG-
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVG-
MAV_4827|M.avium_104 ------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAAT
MLBr_01556|M.leprae_Br4923 ARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAG-
Mflv_5091|M.gilvum_PYR-GCK ---------------------------TSCG---------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------TSCG---------LICNGQD---
Mb1485c|M.bovis_AF2122/97 ---------------------------ALNAPTQALLGRPLIGDGAAGAP
Rv1450c|M.tuberculosis_H37Rv ---------------------------ALNAPTQALLGRPLIGDGAAGAP
MMAR_5341|M.marinum_M ---------------------------AVNAPTMAVLGRPLIGDGVDAAA
MUL_4367|M.ulcerans_Agy99 ---------------------------VVNAPSMALFGRPSIGNGVDGVA
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGING-T
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------AVMPVVAESVASNYGYQSQWVNT
MAV_4827|M.avium_104 --------------------------------------ASAPDRVISAIL
MLBr_01556|M.leprae_Br4923 ----------------------------NGATTAAPVQVDHSAAVVPIVA
Mflv_5091|M.gilvum_PYR-GCK GTGQNG---GILFGNGGSGWNSDVVGMDGGNGGNGGLFG--GNGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1 GTGQNG---GILFGNGGSGWNSEIAGVSGGNGGNAGLFG--GNGGNGGNG
Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAGGAG
Rv1450c|M.tuberculosis_H37Rv GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAGGAG
MMAR_5341|M.marinum_M GSGHNGGAGGLLWGNGGDGG-AGAAGQAGGRGGDAGLIGTGGAGGAGGAG
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGDGGDG
MAB_4284c|M.abscessus_ATCC_199 GNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP
MAV_4827|M.avium_104 GTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAA
MLBr_01556|M.leprae_Br4923 GEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHP
Mflv_5091|M.gilvum_PYR-GCK LGGGNGGNG-----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 LGSGDGGNG-----------------------------------------
Mb1485c|M.bovis_AF2122/97 AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPG
Rv1450c|M.tuberculosis_H37Rv AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPG
MMAR_5341|M.marinum_M GAGGNGGAG-----------------------------------------
MUL_4367|M.ulcerans_Agy99 AAGMTGGSG-----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSG-----------------------------------------
TH_3810|M.thermoresistible__bu GLGGNGGHG-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IASGNQVMS-----------------------------------------
MAV_4827|M.avium_104 AALAQNVGG-----------------------------------------
MLBr_01556|M.leprae_Br4923 GPAPKPGGR-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------GNAG-AFALFGNGGNGGNGGVG-------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------GDAG-LFSLFGRGGNGGNGGVG-------
Mb1485c|M.bovis_AF2122/97 GPGGPGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGG
Rv1450c|M.tuberculosis_H37Rv GPGG---------PGGVGGTGGAGGLGGTLYGAGGHGGAGGPGPIGGVGG
MMAR_5341|M.marinum_M ---------------------GAGGRGGLVFGGGGAGGAGG---------
MUL_4367|M.ulcerans_Agy99 ---------------------GAGGGGGWLWGAGGSGGAAGAGGSGGSGG
MSMEG_0868|M.smegmatis_MC2_155 ---------------------------GLLMGIGGAGGAGGVG-------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------VVGATGAVGAPGVAGATG--------ATGVTSGVVG
Mvan_1264|M.vanbaalenii_PYR-1 --------------IAGATGAVGAPGVAGATG--------ATGVTSNVTG
Mb1485c|M.bovis_AF2122/97 HGGVGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGAGGDAG
Rv1450c|M.tuberculosis_H37Rv HGGVGGAAGLLGVGGHGGAGGHGAEGVAGAAG-EDLSPHGTSGGVGGDAG
MMAR_5341|M.marinum_M ---------------DGGTATIGAQGLAGQTG--------QTGHTGGAGG
MUL_4367|M.ulcerans_Agy99 --WLWGNAGQTAGAGVGGAGGAGGAGDAGDQG--------VSGVAPGEAG
MSMEG_0868|M.smegmatis_MC2_155 ---------------ADGTSAHVDGGTGGTGG--------TGGGTGGTGG
TH_3810|M.thermoresistible__bu ----------------GGTGIISLLSLAGNGG------------------
MAB_4284c|M.abscessus_ATCC_199 --------------PSGNVDSFNRGPLLDLS-------------------
MAV_4827|M.avium_104 -----------------AMGYERTAVLLVEPD------------------
MLBr_01556|M.leprae_Br4923 ------------PPRVGNNPFSSAQSVARPIP------------------
Mflv_5091|M.gilvum_PYR-GCK GNGED--------------AVGYGATGAAG--------------------
Mvan_1264|M.vanbaalenii_PYR-1 GNGAD--------------AVGYGATGAAG--------------------
Mb1485c|M.bovis_AF2122/97 DGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALIVAGDNGGDGGN
Rv1450c|M.tuberculosis_H37Rv DGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRALIVAGDNGGD---
MMAR_5341|M.marinum_M DGGAGGRGGWLWSAGGDGGAGGLGGTGGAG--------------------
MUL_4367|M.ulcerans_Agy99 AVGFAGGAGGAGGAGGNGVGGGVNGAGGAGGAG-----------------
MSMEG_0868|M.smegmatis_MC2_155 IGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVG--
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGGDRGAGANGN
Rv1450c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5341|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------AAGAAGAAGAAGAVG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------AAGAAGAAGKAGAVG--------------
Mb1485c|M.bovis_AF2122/97 QAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGA
Rv1450c|M.tuberculosis_H37Rv ----------------PGAGGAGGTGGAGSTIGAHGAAGASPTSGGNGGA
MMAR_5341|M.marinum_M --------------------GAGGTGIAATTAGGIG--------------
MUL_4367|M.ulcerans_Agy99 --------------------GVGGGGGAGASGVGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 ------------------SETRGGTGGAGGTGGQST--------------
TH_3810|M.thermoresistible__bu ---------------------NGGNGYRTTDNNALD--------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------FGDLQFGNRDTTAIG--------------
MAV_4827|M.avium_104 ---------------------TATLAVVETSDGSIP--------------
MLBr_01556|M.leprae_Br4923 ---------------------RPPAPRPSASPSSMS--------------
Mflv_5091|M.gilvum_PYR-GCK ------------SAGAAGEAGETGTWGNAGLPGKAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------SAGTAGSAGAPGVWGNAGLPGAAG--------------
Mb1485c|M.bovis_AF2122/97 GGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPN
Rv1450c|M.tuberculosis_H37Rv GGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPSGGDPN
MMAR_5341|M.marinum_M -----------QAGGDGGAGGAGGAGGNGGAGGATG--------------
MUL_4367|M.ulcerans_Agy99 -----------VAGGDGGTGGAGGAAGVGGAAGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 ------------AAGPGKGGGGGGGGGGAILIGANG--------------
TH_3810|M.thermoresistible__bu -------------GGHGGNGGNVGFFSLFNLGGAGG--------------
MAB_4284c|M.abscessus_ATCC_199 ----------------DGAVAVGGSNSGPIASGQGS--------------
MAV_4827|M.avium_104 -----------DVYKQQIRAESYGDAAGQLSAMVAG--------------
MLBr_01556|M.leprae_Br4923 ------------PRPGGAVGGGGPRPPRTGVPRPGG--------------
.
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGGGGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNGATGATGLNGLGA
Rv1450c|M.tuberculosis_H37Rv GGGGGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNGATGATGLNGLGA
MMAR_5341|M.marinum_M -----------------------------------WFGSTGMT-------
MUL_4367|M.ulcerans_Agy99 -----------------------------------TGGAAGVA-------
MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------GTVDGHAIG-------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------DAGGAGAVGAAG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------AAGGAGAIGTAG
Mb1485c|M.bovis_AF2122/97 GADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAG
Rv1450c|M.tuberculosis_H37Rv GADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSMGAGGAGGNGGAG
MMAR_5341|M.marinum_M --------------------------------------GAGGAGGHGGNG
MUL_4367|M.ulcerans_Agy99 --------------------------------------GTGGDGGDGGAG
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------GNGGNGGNGSTT
TH_3810|M.thermoresistible__bu ---------------------------------------WGGSGVDG-VD
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------TAVNGDVRDSN
MAV_4827|M.avium_104 --------------------------------------LEKLESLPGGLL
MLBr_01556|M.leprae_Br4923 --------------------------------------GRPGAPVGGRSD
Mflv_5091|M.gilvum_PYR-GCK AAGTVGTAGATGGT------------GTGANGGAGGVGGVGGTGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 VAGAAGTAGATGGT------------GVGGNGGAGQAGGIGGTGAAGAAG
Mb1485c|M.bovis_AF2122/97 GMGGDGGNGAKGTFDNGGD----GVGGNGGNGGSRGIGGAGGIGGAGSTA
Rv1450c|M.tuberculosis_H37Rv GMGGDGGNGAKGTFDNGGD----GVGGNGGNGGSRGIGGAGGIGGAGSTA
MMAR_5341|M.marinum_M AIAGNGGAGANGDMTHLD-------GGNGGNGGNPGLGGAGGNGGAGSHA
MUL_4367|M.ulcerans_Agy99 GAGSDASLAGQAGFAGGS-------GGAGGVGGSAGAGGVNGSGGDGGAG
MSMEG_0868|M.smegmatis_MC2_155 AAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVY
TH_3810|M.thermoresistible__bu VVGGNP------------------------DGGTPGAHGESHTPGVYTDR
MAB_4284c|M.abscessus_ATCC_199 IINADHGSNVGVDQ-----------SQTRVGGDYTNVSGHGSADIDKSVT
MAV_4827|M.avium_104 LVGSGVDVAPLKQVLQTTT----FLDVSVAEEPETALARGAALAAANAPL
MLBr_01556|M.leprae_Br4923 AGGGNYRGGGVGALPGGGSG---GFRGRPGGGGHGGGGRPGQRGGAAGAF
Mflv_5091|M.gilvum_PYR-GCK GAGGLGETGTTG--GAGGVGGQG----TAGGTGGVGGIGGAG---STGAV
Mvan_1264|M.vanbaalenii_PYR-1 QAGTAGETGVTG--GVGGIGGQG----TEGGTGGVGGVGGVG---ATGGA
Mb1485c|M.bovis_AF2122/97 GADGARGATPTS-GGNGGTGGNGANATVAGGAGGAGGKGGNGGLVGNGGA
Rv1450c|M.tuberculosis_H37Rv GADGARGATPTS-GGNGGTGGNGANATVAGGAGGAGGKGGNGGLVGNGGA
MMAR_5341|M.marinum_M GAHGLAGSSPTTNAGHGGKGGDGYTSTDPGTDGGNGGHGGAGGYYGNGGA
MUL_4367|M.ulcerans_Agy99 AAGGAGGASATV-AGSGGVGGDGGAGGAAGGGVGAASLGGDG---GHAGA
MSMEG_0868|M.smegmatis_MC2_155 AYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGD
TH_3810|M.thermoresistible__bu QGED----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQAN--------
MAV_4827|M.avium_104 FASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYS------
MLBr_01556|M.leprae_Br4923 GRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASL
Mflv_5091|M.gilvum_PYR-GCK GG--VGGKGIQ----------GGQGLQGGKGGDGGAGGKGGDADS---MG
Mvan_1264|M.vanbaalenii_PYR-1 GG--VGGKGIQ----------GGQGLQGGQGGDGGTGGTGGDATS---MG
Mb1485c|M.bovis_AF2122/97 GG--KGGDGMAGVAGSSPTTAGESGTSGQNGGAGGAGGAGGRGGD---FG
Rv1450c|M.tuberculosis_H37Rv GG--KGGDGMAGVAGSSPTTAGESGTSGQNGGAGGAGGAGGRGGD---FG
MMAR_5341|M.marinum_M GG--NGGNGATGNLGAAPLAEGEPGGDGGAGGNGGTGGAGGAGGV---IS
MUL_4367|M.ulcerans_Agy99 GG--AGGEGLSGGFN-----TGAAGGIGGAGGAGGTGGDSGGVGG---VN
MSMEG_0868|M.smegmatis_MC2_155 GGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASD---GG
TH_3810|M.thermoresistible__bu ---------------------GEDGTGTGIGGRGGNGGSSSGTHP---MA
MAB_4284c|M.abscessus_ATCC_199 --------------------IGTSTSAGGSAAVGGNAGLAGNAGL---AG
MAV_4827|M.avium_104 -------------------AVGEEDAESPTVVIEKLFLPEDSEPR---RR
MLBr_01556|M.leprae_Br4923 SDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVV
* .
Mflv_5091|M.gilvum_PYR-GCK SAGATG---------GKGGNGGNGGRGGLFGK-GGNAGNGADGGTGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 EAGATG---------GKGGNGGNGGRGSLFGR-GGNAGNGGNGGTGGNGG
Mb1485c|M.bovis_AF2122/97 GDGGTGGAGGNGADGGAGGNGANGANATTPGAKGGDGGHGGPGAQGGNGG
Rv1450c|M.tuberculosis_H37Rv GDGGTG---------GAGGNGANGANATTPGAKGGDGGHGGPGAQGGNGG
MMAR_5341|M.marinum_M GDGGAGGRGGGGGNGGNGAAGANGTNATISGTNGGNAGAGGNGGNGGTGG
MUL_4367|M.ulcerans_Agy99 GDGGAG---------GGGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGV
MSMEG_0868|M.smegmatis_MC2_155 KGGNGG----DALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTN
TH_3810|M.thermoresistible__bu EDGEHV--------------------KALDGRPGLDGGNGSHGGN-----
MAB_4284c|M.abscessus_ATCC_199 NAGLAG-------------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 PVLLVG-----------SGLAVVGISAVLALEIALAIGIRTTGTVALQPT
MLBr_01556|M.leprae_Br4923 SPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDT
*
Mflv_5091|M.gilvum_PYR-GCK -AGGTG-----------GTGGAGGTGGTGGTGGIGGAGSTG---------
Mvan_1264|M.vanbaalenii_PYR-1 -NGGTG-----------GTGGNGGTGGTGGTGGIGGAGSTG---------
Mb1485c|M.bovis_AF2122/97 -QGGPGGLAGN-LFGQNGIQGVGGSGGKGGAGGLAGDGGNGANGN-FAFG
Rv1450c|M.tuberculosis_H37Rv -QGGPGGLAGN-LFGQNGIQGVGGSGGKGGAGGLAGDGGNGANGN-FAFG
MMAR_5341|M.marinum_M -NGGAGGAAT---HGSAGANGAGGAGGNGGDGAIAGDGGTGANGDATHFD
MUL_4367|M.ulcerans_Agy99 SAGGTGGSAGD-GGAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGAGID
MSMEG_0868|M.smegmatis_MC2_155 IAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------AGLAGNAGLAGNAGLAGNAG-----------
MAV_4827|M.avium_104 ----------------PNQHLIVPTEQAPAPPPVQASAPQP---------
MLBr_01556|M.leprae_Br4923 --------------IRKANVREAEAGGITQHIGAYQVGVDLDGSERLITF
Mflv_5091|M.gilvum_PYR-GCK -GTGGTGGTGGTGGTGGTGGTGGTGGTGG----TGGKGGTG------GTG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGTGGTGGTGGTGGTGGTGG----TGGKGGTG------GTG
Mb1485c|M.bovis_AF2122/97 DGNGGHGGNGGNPGAGGQGGSGGAGSTPG----AKGAHGFTPTSG--GDG
Rv1450c|M.tuberculosis_H37Rv DGNGGHGGNGGNPGAGGQGGSGGAGSTPG----AKGAHGFTPTSG--GDG
MMAR_5341|M.marinum_M GGNGGNGANPGIGGLGGAGGTSGDGTTPA----AHGTNGTTPTTTN-GSG
MUL_4367|M.ulcerans_Agy99 GGAGGAGGTGGAAGFPGGGGTTGAWGTGG----AGGAGGAGGAGDHGGVG
MSMEG_0868|M.smegmatis_MC2_155 KAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTG-GNG
TH_3810|M.thermoresistible__bu ---GGHGGRGGFLGIGGSGG------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAG---------------------
MAV_4827|M.avium_104 -KISVPEPVAAPKPLSPPVAAPLPAAPPP---------------------
MLBr_01556|M.leprae_Br4923 IDTPGHEAFTAMRARGAKATDIAILVVAADDG------------------
.
Mflv_5091|M.gilvum_PYR-GCK GAGGTGGD-------GGTGGTGGTG------GTGGTGGTGGTGGAG----
Mvan_1264|M.vanbaalenii_PYR-1 GDGGTGGT-------GGTGGTGGTG------GTGGTGGTGGTGGAG----
Mb1485c|M.bovis_AF2122/97 GDGGNGGHSQVVGGNGGDGGNGGNG---GSAGTGGNGGRGGDGAFGGMSA
Rv1450c|M.tuberculosis_H37Rv GDGGNGGNSQVVGGNGGDGGNGGNG---GSAGTGGNGGRGGDGAFGGMSA
MMAR_5341|M.marinum_M GRGGDGYTSTDPTLNGGKGGTGGNG---GDYGNGGAGGNGGNGATGTTGT
MUL_4367|M.ulcerans_Agy99 VNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGAGA
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGG
TH_3810|M.thermoresistible__bu --------------------------------WGGHGGNGGD--------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------NAGLAGNAGLAGNAG---
MAV_4827|M.avium_104 --------------------------------AAPPLPEAPPIPAAPPVV
MLBr_01556|M.leprae_Br4923 -----------------------------VMPQTVEAINHAQAADVPIVV
Mflv_5091|M.gilvum_PYR-GCK -----------DGTGGTGGTGGTGGQGGQGGQGGTGGTGGQGGLGGGGG-
Mvan_1264|M.vanbaalenii_PYR-1 -----------DGLGGTGGTGGTGGFGGQGGQGGTGGTGGQGGLGGVGG-
Mb1485c|M.bovis_AF2122/97 NATNPGENGPNGNPGGNGGAGGAGGAGLNGGNGGAGGNGGLGGFGGNGAA
Rv1450c|M.tuberculosis_H37Rv NATNPGENGPNGNPGGNGGAGGAGGAGLNGGNGGAGGNGGLGGFGGNGAA
MMAR_5341|M.marinum_M NPT-PHPITSHANPGTDG-TTSNGGNGTTGSDGTAAGQ--QGGTGGAGYN
MUL_4367|M.ulcerans_Agy99 SGIGAGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGAAGSAGDGGAGGA
MSMEG_0868|M.smegmatis_MC2_155 NGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVN
TH_3810|M.thermoresistible__bu -------------------TDADGGNGGDGGNGGSAGRGGTGGLR-----
MAB_4284c|M.abscessus_ATCC_199 ----------LAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGG-
MAV_4827|M.avium_104 PVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQP-
MLBr_01556|M.leprae_Br4923 AVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALL
Mflv_5091|M.gilvum_PYR-GCK ------------TGGQGGTGGTGGQGGTGGTGGTG----GTGGT------
Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGTGGTGGQGGTGGTGGTG----GTGGT------
Mb1485c|M.bovis_AF2122/97 GANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGGA------
Rv1450c|M.tuberculosis_H37Rv GANGVAVGAPGQPGGAGGHGGAGGNGGAGGNGGQGVVSDGAGGA------
MMAR_5341|M.marinum_M SGGPGDTNPFGGNGGTGGMGGPGTQGGAGGSGGYGPLVGGWGGD------
MUL_4367|M.ulcerans_Agy99 GGAGDDGSAGVVSGDPGTAGKAGGAGGAGGVGGNG-VAGGVNGS------
MSMEG_0868|M.smegmatis_MC2_155 NGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTA
TH_3810|M.thermoresistible__bu ----------------GVFGINGGNGRAG---------------------
MAB_4284c|M.abscessus_ATCC_199 ------------VLNTGVSGAIGGSSHVGGAINES---------------
MAV_4827|M.avium_104 -------------PSPPQVGGTVPQSPPQHQTPPG---------------
MLBr_01556|M.leprae_Br4923 EAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRG-----
Mflv_5091|M.gilvum_PYR-GCK -GGAGGDGG--------------------LGGLGGFGGSGG---------
Mvan_1264|M.vanbaalenii_PYR-1 -GGAGGDGG--------------------LGGLGGFGGVGG---------
Mb1485c|M.bovis_AF2122/97 -GGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGG
Rv1450c|M.tuberculosis_H37Rv -GGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGGNAGNAGAGGPGG
MMAR_5341|M.marinum_M -GGAGGDG----------------------GGAGGDGGTGG-ASSGANGF
MUL_4367|M.ulcerans_Agy99 -GGAGGAGG--------------------AGGTGGAGASGVPASVD--GG
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGNGG-------------------TLGATNGTGGAATIVAYNVVQA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------LGGSGS------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------TGGQGGLGG-------------PGGSTGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGQGGQGG-------------PGGSTGGAGGA
Mb1485c|M.bovis_AF2122/97 TGSTAGKAGP-AGSILHDGGNGGHGG-------------HGAASGGNGGP
Rv1450c|M.tuberculosis_H37Rv TGSTAGKAGP-AGSILHDGGNGGHGG-------------HGAASGGNGGP
MMAR_5341|M.marinum_M TGQAG------------NGGNGGIGG-------------NGGGSGGNGGD
MUL_4367|M.ulcerans_Agy99 DGGAGG-----------AGGAAGTGG-------------SGG-SAGNTGA
MSMEG_0868|M.smegmatis_MC2_155 NPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGD
TH_3810|M.thermoresistible__bu -----------------LGGRGXXXX------------------GGGVGA
MAB_4284c|M.abscessus_ATCC_199 -----------------VGGSTAVGG--------------GAHTGVGGGV
MAV_4827|M.avium_104 -----------------EGTPPKPDG-------------PGNYGGGHVPT
MLBr_01556|M.leprae_Br4923 ---------------TLRIGDSVVAG-----------DAYGRVRRMVDEH
Mflv_5091|M.gilvum_PYR-GCK GGQAGTAGKGG-----LFGGSGSAGKAGATGAAGASGGKGAQGATGAQGA
Mvan_1264|M.vanbaalenii_PYR-1 GGQAGVAGKGG-----LFGGSGSAGTAGVTGASGASGGKGAQGATGAQGA
Mb1485c|M.bovis_AF2122/97 GGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
Rv1450c|M.tuberculosis_H37Rv GGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
MMAR_5341|M.marinum_M GGDANYAIPWGNSAYAGDGGYGGDGGTGATGGTGSDGGAGGAGGAGGLYG
MUL_4367|M.ulcerans_Agy99 GGAGGAGGAGGSAASTGVNGDGGAGGAGGVGGLG--GDSAATAGGGGAGG
MSMEG_0868|M.smegmatis_MC2_155 GIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGG
TH_3810|M.thermoresistible__bu AVRSGNG---------VFSGGGGTPSAG----------------------
MAB_4284c|M.abscessus_ATCC_199 STGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS
MAV_4827|M.avium_104 PGAGGSGG----------SGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGG
MLBr_01556|M.leprae_Br4923 GVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRN
. .
Mflv_5091|M.gilvum_PYR-GCK --------TGAQGATGATGAAGKAGATGAAGAAGAAGSAGTTGAQGSAGT
Mvan_1264|M.vanbaalenii_PYR-1 --------TGAQGATGATGASGAQGSAGSAGSAGVAGSAGTTGAQGSAGT
Mb1485c|M.bovis_AF2122/97 --------NGGRGGNGGQGLTGAGGN-GGTGGTPGNGGNGGNGASGDLVT
Rv1450c|M.tuberculosis_H37Rv --------NGGRGGNGGQGLTGAGGN-GGTGGTPGNGGNGGNGASGDLVT
MMAR_5341|M.marinum_M --------NGGNGGTGGTG--GDGGT-GATGGTGGTGGNGGDSTGNSLSS
MUL_4367|M.ulcerans_Agy99 --------DGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGSDGIIPS
MSMEG_0868|M.smegmatis_MC2_155 PSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGV
TH_3810|M.thermoresistible__bu -----------------------FGVPTTIQFPAGSCTSRAVSREGIMPS
MAB_4284c|M.abscessus_ATCC_199 --------------HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVNT
MAV_4827|M.avium_104 ----------------------TGGSGGGHVPTPGAGTPGGSGGGHLPFP
MLBr_01556|M.leprae_Br4923 ALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVD
Mflv_5091|M.gilvum_PYR-GCK NGANGANGSQG-AAGKAGATG-TTGATGAAGEDGDAGSGGSGINGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 NGANGANGSQG-AAGKAGATG-TTGATGAAGDAGDPGSEAVDINGGAGGA
Mb1485c|M.bovis_AF2122/97 SPGDGGGGGRGGDAGRGGDAG-LGGSSGPGGTPGDWGTGGTGGTGGTGGQ
Rv1450c|M.tuberculosis_H37Rv SPGDGGGGGRGGDAGRGGDAG-LGGSSGPGGTPGDWGTGGTGGTGGTGGQ
MMAR_5341|M.marinum_M LPGNGGDGGDGGTGGTGGTGG-SGGDGGAAGAGGTYGQSGTNGTGGAAGS
MUL_4367|M.ulcerans_Agy99 NGGLGGNGGNGGNGGQAFGDG-VGGAGGIGGKGGNAAIGTIVINGGVGGA
MSMEG_0868|M.smegmatis_MC2_155 ATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGN
TH_3810|M.thermoresistible__bu SRAASARAGAACASSTSRSRR-------------SFCCSRA---------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGS-VGGSTAVGGGAHTSAINDALGGSGSVG-
MAV_4827|M.avium_104 GAGSTPGGSGGGHLPTPGAGT-------PGGGLGGFGGGHAPAPG-----
MLBr_01556|M.leprae_Br4923 DEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGV
. .
Mflv_5091|M.gilvum_PYR-GCK GGAG--------GEGGEGGDGG---------KGGA------------GAE
Mvan_1264|M.vanbaalenii_PYR-1 GGAG--------GEGGEGGAGG---------AGGD------------GSE
Mb1485c|M.bovis_AF2122/97 GANGGL----TGGRGGTGGNGG---------AGGTGGTGHNGSQPGMGGN
Rv1450c|M.tuberculosis_H37Rv GANGGL----TGGRGGTGGNGGNGNTGGTGGAGGTGGTGHNGSQPGMGGN
MMAR_5341|M.marinum_M GGEG--------GAGGTGGDGG---------SGGVTYDSDYNPGPPYGTS
MUL_4367|M.ulcerans_Agy99 GGSGGLGGATEDGVGGVGCAGG---------AGGNGGRGD--MLFTVGGS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------GSTAVGGG----------------------AHTSAI
MAV_4827|M.avium_104 -----------------------------------------------GGL
MLBr_01556|M.leprae_Br4923 EIRYYLVIYQAIDDIEKALRGMLKP------------------IYEENQL
Mflv_5091|M.gilvum_PYR-GCK GGAGGGGGAGGSGAGGAGGAGGSGGSGGSGGSG--------GSGGAAGDS
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGGAGGSGTGGAGGAGGSGGSGGSGGAG--------GSGGAAGDS
Mb1485c|M.bovis_AF2122/97 GGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPF-GTGTGGTGGHGGQG
Rv1450c|M.tuberculosis_H37Rv GGAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPF-GTGTGGTGGHGGQG
MMAR_5341|M.marinum_M GQS---GATGATGATGQAGMAGT--TPGTGTPGPG-GDGGDGTGGNGGNG
MUL_4367|M.ulcerans_Agy99 GGTG--GDGGGGGSASGSGTGGSGGTGGVGGIGGD-GK-LGGFGGDGGDG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHT
MAV_4827|M.avium_104 GGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----------------
MLBr_01556|M.leprae_Br4923 GRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTS
Mflv_5091|M.gilvum_PYR-GCK DD--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 D---------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
Rv1450c|M.tuberculosis_H37Rv GGGGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
MMAR_5341|M.marinum_M GPG-FP----------------------------------------
MUL_4367|M.ulcerans_Agy99 GDGGFGVIGGQGGGGGFGGLGGTGAGGAPSDKGINGEPGNPG----
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
TH_3810|M.thermoresistible__bu ----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TLPGAEHH--------------------------------------
MAV_4827|M.avium_104 ----------------------------------------------
MLBr_01556|M.leprae_Br4923 LRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA---