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MSFVFASPEVLGAAAAQAAVIGSGVQTAGAWAAGPTTALAGALGADEVSVAVAQLFDGHGQAYQAISAQA AVFHGRFVAALNAAADSYAGAEAAGVSVLQSAGADVMGALNAPTMAWLGRPLIGDGANGVDGTGGNGGAG GLLWGNGGRGGSGAAGQAGGRGGSAGLIGTGGAGGAGGASVSGAGGVGGGGGAGGWLFGAGGQGGTGGNG LTTAGVGGHGGGTGLFGAGGAGGTGGISGTGVGGGGGHGGNGGWVAGDGGAGGAGGTSNTGAGGSGGGAG RGGWVFGDGGAGGAGGDGATGAAGAQGLTGQTGQTGHDGGAGGAGGAGGRGGWLFSAGGNGGAGGAGGAG GAGGAGGAGATATTAGTSGGNGGNGGAGGTGGDGGAGGAGGATGWFGSTGTTGAGGNGGTGGNGAIAGNG GAGANGDVLHLDGGNGGNGGNPGASGAGGSGGTGSRTGAHGLAGTTPTTNAGDGGRGGDGYTSTDPTLNG GAGGNGGNGGDYGNGGAGGNGGNGATGALGTAPPAAGDPGGNGGNGSNGGNGGAGGTGGLIAGDGGAGGH GGGGGNGGNGAAGANGTNATISGTNGGNAGAGGNGGNGGTGGNGGAGGAATHGSAGANGAGGAGGNGGDG AIAGDGGTGANGDATHFDGGNGGNGANPGIGGLGGAGGTSGDGTTPAAHGTNGTTPTTTNGSGGRGGDGY TSTDPTLNGGKGGTGGNGGDYGNGGAGGNGGNGATGTTGTNPTPHPVTSTANPGTDASGNQTLFNGGTGD NGAYAGQAGGNGGDGYADFDQPFGGNGGDGGIGGPGTIGGTGGNGGYAAIVGGWGGDGGAGGDGGGAGGN GGNGGLGLGTSALPGQGGEGGNGGNGGAGGGTGGTGGTGGGGFHGPGGAAGDGGTGGIGATGGDGSNGGA GGAGGTGGLYGNGGNGGTGGTGGNGGTGATGGTGGDGGIGGSSEAGTAAVGGDGGDGGTGGTGGNGGNGG DGGAAGAGGTYGQSGTNGTGGDAGTGGSGGEGGTGGNGGAGGETSSTQSPDGLSGATGAMGASGQDGIAG TTPGTGTGGPPAGGPDGNGGDGGPGVPGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5308 | - | - | 100% (1079) | PE-PGRS family protein |
| M. marinum M | MMAR_5307 | - | 0.0 | 90.83% (1080) | PE-PGRS family protein |
| M. marinum M | MMAR_5341 | - | 0.0 | 68.39% (1028) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 53.22% (1135) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-171 | 46.32% (829) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 0.0 | 47.58% (1299) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 9e-10 | 36.96% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-48 | 30.28% (578) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 8e-25 | 44.74% (152) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-159 | 39.45% (1123) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-49 | 41.42% (309) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 47.20% (1123) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-168 | 45.17% (828) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1485c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5308|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 ------------------MSLVIVAPETVAAAALDVARIGSSIGVANSAA
Rv1450c|M.tuberculosis_H37Rv ------------------MSLVIVAPETVAAAALDVARIGSSIGAANAAA
MMAR_5308|M.marinum_M ------------------MSFVFASPEVLGAAAAQAAVIGSGVQTAGAWA
MUL_4367|M.ulcerans_Agy99 ------------------MSFVSVGPGLLEAAARDLAGLGAGLREANLAA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------MSIIDFILNLFRDPVEAASYVADPEAALANAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAID
Mb1485c|M.bovis_AF2122/97 AGSTTSVL-AAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLS
Rv1450c|M.tuberculosis_H37Rv AGSTTSVL-AAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLS
MMAR_5308|M.marinum_M AGPTTALAGALGADEVSVAVAQLFDGHGQAYQAISAQAAVFHGRFVAALN
MUL_4367|M.ulcerans_Agy99 AGATVGVL-PAAGDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALT
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LSAVSAAQVGAVMP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAAL
Mb1485c|M.bovis_AF2122/97 -----------------------AAVGSYVSAEATNAAPLATLEHNVLNA
Rv1450c|M.tuberculosis_H37Rv -----------------------AAVGSYVSAEATNAAPLATLEHNVLNA
MMAR_5308|M.marinum_M -----------------------AAADSYAGAEAAGVSVLQSAGADVMGA
MUL_4367|M.ulcerans_Agy99 -----------------------AGGSAYGQAEALNMWPLQELEQQALGV
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------VVAESVASN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 R---------------------------------------DALAARRIDN
Mb1485c|M.bovis_AF2122/97 LN--------------------APTQALLG--------RPLIGDGAAGAP
Rv1450c|M.tuberculosis_H37Rv LN--------------------APTQALLG--------RPLIGDGAAGAP
MMAR_5308|M.marinum_M LN--------------------APTMAWLG--------RPLIGDGANGVD
MUL_4367|M.ulcerans_Agy99 VN--------------------APSMALFG--------RPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YG----------------------------------------YQSQWVNT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VM------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAGGAG
Rv1450c|M.tuberculosis_H37Rv GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAGGAG
MMAR_5308|M.marinum_M GTGGNGGAGGLLWGNGGRGG-SGAAGQAGGRGGSAGLIGTGGAGGAGGAS
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
Mflv_5091|M.gilvum_PYR-GCK QN------GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1 QN------GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155 DNP-NGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGDG---
MAB_4284c|M.abscessus_ATCC_199 GNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVE
Mb1485c|M.bovis_AF2122/97 AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPG
Rv1450c|M.tuberculosis_H37Rv AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPG
MMAR_5308|M.marinum_M VSG-----------------------------------------------
MUL_4367|M.ulcerans_Agy99 AAG-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGN-----------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 SGD-----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GLD-----------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IAS-----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TSD-----------------------------------------------
Mb1485c|M.bovis_AF2122/97 GPGGPGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGP-IGGVG
Rv1450c|M.tuberculosis_H37Rv GPGG---------PGGVGGTGGAGGLGGTLYGAGGHGGAGGPGP-IGGVG
MMAR_5308|M.marinum_M ----------------AGGVGGGGGAGGWLFGAGGQGGTGGNGLTTAGVG
MUL_4367|M.ulcerans_Agy99 ---------------MTGGSGGAGGGGGWLWGAGGSGGAAGAGG-SGGSG
Mflv_5091|M.gilvum_PYR-GCK -----------------GGNGGNAGAF-ALFGNGGNGGNGGVGV------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GGNGGDAGLF-SLFGRGGNGGNGGVGI------
MSMEG_0868|M.smegmatis_MC2_155 -----------------GGNGGSGG---LLMGIGGAGGAGGVGA------
TH_3810|M.thermoresistible__bu -------------------------------GDGGLGGNGGHG-------
MAB_4284c|M.abscessus_ATCC_199 --------------------------GNQVMSPSGNVDSFNRGP------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------GSIPDVYKQQIRAESYGDAAGQLS------
Mb1485c|M.bovis_AF2122/97 ----GHGGVGGAAGLLGVGGHGGAGGHGAAGIAGAAGKGGIFPDGSNGGA
Rv1450c|M.tuberculosis_H37Rv ----GHGGVGGAAGLLGVGGHGGAGGHGAEGVAGAAG-EDLSPHGTSGGV
MMAR_5308|M.marinum_M ----GHG---GGTGLFGAGGAGGTGGISGTGVG-----------------
MUL_4367|M.ulcerans_Agy99 GWLWGNAGQTAGAGVGGAGGAGGAGDAGDQGVS-----------------
Mflv_5091|M.gilvum_PYR-GCK ---------VGATGAVG--APGVAGATGATGVTS----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------AGATGAVG--APGVAGATGATGVTS----------------
MSMEG_0868|M.smegmatis_MC2_155 ---------DGTSAHVDGGTGGTGGTGGGTGGTG----------------
TH_3810|M.thermoresistible__bu ---------------------------GGTGIIS----------------
MAB_4284c|M.abscessus_ATCC_199 -------------LLDLSFGDLQFGNRDTTAIG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------AMVAGLEKLESLPG----------------
Mb1485c|M.bovis_AF2122/97 GGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRALIVAGDNG
Rv1450c|M.tuberculosis_H37Rv GGDAGDGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRALIVAGDNG
MMAR_5308|M.marinum_M ----GGGGHGGNGGWVAGDGGAGGAGGTSNTG------------------
MUL_4367|M.ulcerans_Agy99 ------GVAPGEAGAVGFAGGAGGAGGAGGNG------------------
Mflv_5091|M.gilvum_PYR-GCK ------GVVGGNGEDAVGYGATGAAGAAGAAG------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------NVTGGNGADAVGYGATGAAGAAGAAG------------------
MSMEG_0868|M.smegmatis_MC2_155 ------GIGGTGGGLFGLLGHSGSTGAAGAAG------------------
TH_3810|M.thermoresistible__bu ------------LLSLAGNGGNGGNGYRTTDN------------------
MAB_4284c|M.abscessus_ATCC_199 -------------DGAVAVGGSNSGPIASGQG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------GLLLVGSGVDVAPLKQVLQT------------------
Mb1485c|M.bovis_AF2122/97 GDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGGVGGDRGA
Rv1450c|M.tuberculosis_H37Rv GD------------------------------------------------
MMAR_5308|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAAGASPTSG
Rv1450c|M.tuberculosis_H37Rv ---------------------PGAGGAGGTGGAGSTIGAHGAAGASPTSG
MMAR_5308|M.marinum_M -----------------------AGGSG----------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPS
Rv1450c|M.tuberculosis_H37Rv GNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNGAPGAPPS
MMAR_5308|M.marinum_M --GGAG-------RGGWVFGDGGAGGAG---GDGATGAAGAQGLTGQTGQ
MUL_4367|M.ulcerans_Agy99 -------------VGGGVNGAGGAGGAG------GVGGGGGAGASGVGAG
Mflv_5091|M.gilvum_PYR-GCK --------------AAGAAG--------------AVGSAGAAGEAGETGT
Mvan_1264|M.vanbaalenii_PYR-1 --------------AAGKAG--------------AVGSAGTAGSAGAPGV
MSMEG_0868|M.smegmatis_MC2_155 --------------NGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------STAVNGDVRDSNI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------TTFLDVSVAEEPE
Mb1485c|M.bovis_AF2122/97 GGDPNGGGGGAGGAGGKGGD-------------GGAQAGDGGAGGAG---
Rv1450c|M.tuberculosis_H37Rv GGDPNGGGGGAGGAGGKGGD-------------GGAQAGDGGAGGAG---
MMAR_5308|M.marinum_M TG-HDGGAGGAGGAGGRGGW-------------LFSAGGNGGAGGAG---
MUL_4367|M.ulcerans_Agy99 VAGGDGGTGGAGGAAGVGG--------------AAGTGGTGGAAGVA---
Mflv_5091|M.gilvum_PYR-GCK WG--NAGLPGKAGDAGGAG----------------AVGAAGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 WG--NAGLPGAAGAAGGAG----------------AIGTAGVAG------
MSMEG_0868|M.smegmatis_MC2_155 GGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTT
TH_3810|M.thermoresistible__bu ----NALDGGHGG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 INADHGSNVGVDQSQTR---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TALARGAALAAANAPLFAS-------------------------------
Mb1485c|M.bovis_AF2122/97 GKGGNGGNGATGATGLNGLGAGADGT-DGGKGGNGGAGGGGGAGGQGGKA
Rv1450c|M.tuberculosis_H37Rv GKGGNGGNGATGATGLNGLGAGADGT-DGGKGGNGGAGGGGGAGGQGGKA
MMAR_5308|M.marinum_M GAGGAGGAGGAGAT------ATTAGT-SGGNGGNGGAGGTGGDGGAGG-A
MUL_4367|M.ulcerans_Agy99 GTGGDGGDGGAG-------GAGSDAS-LAGQAG--FAGGSGGAGGVGG--
Mflv_5091|M.gilvum_PYR-GCK TVGTAGATGGTG---------------TGANGGAGGVGGVGGTGAAG---
Mvan_1264|M.vanbaalenii_PYR-1 AAGTAGATGGTG---------------VGGNGGAGQAGGIGGTGAAG---
MSMEG_0868|M.smegmatis_MC2_155 AAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGS--
TH_3810|M.thermoresistible__bu ---------------------------NGGNVGFFSLFNLGG--------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------VGGDYTNVSGHGSADIDKSVT--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------STAALAYAQDPGTGAVDQYSLP-
Mb1485c|M.bovis_AF2122/97 LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG
Rv1450c|M.tuberculosis_H37Rv LAATHQDGSMGAGGAGGNGGAGGMGGDGGNGAKGTFDNGGDGVGGNGGNG
MMAR_5308|M.marinum_M GGATGWFGSTGTTGAGGNGGTGGNGAIAGNGGAGANGDVLHLDGGNGGNG
MUL_4367|M.ulcerans_Agy99 --------SAGAGGVNGSGGDGGAGAAGGAGGASATVAGSGGVGGDGGAG
Mflv_5091|M.gilvum_PYR-GCK -------------AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGI
Mvan_1264|M.vanbaalenii_PYR-1 -------------AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 VYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAG
TH_3810|M.thermoresistible__bu --------------AGGWGGSGVDG---------------------VDVV
MAB_4284c|M.abscessus_ATCC_199 -------------VVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------DYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE
Mb1485c|M.bovis_AF2122/97 GSRG-IGGAGGIGGAGSTAGADGARG------------ATPTS-GGNGGT
Rv1450c|M.tuberculosis_H37Rv GSRG-IGGAGGIGGAGSTAGADGARG------------ATPTS-GGNGGT
MMAR_5308|M.marinum_M GNPG-ASGAGGSGGTGSRTGAHGLAG------------TTPTTNAGDGGR
MUL_4367|M.ulcerans_Agy99 GAAGGGVGAASLGGDGGHAGAGGAGG------------EGLSGGFNTGAA
Mflv_5091|M.gilvum_PYR-GCK GGAGSTGAVGGVGGKG----IQGGQG-------------LQGGKGGDGGA
Mvan_1264|M.vanbaalenii_PYR-1 GGVGATGGAGGVGGKG----IQGGQG-------------LQGGQGGDGGT
MSMEG_0868|M.smegmatis_MC2_155 GDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGK
TH_3810|M.thermoresistible__bu GGNP------------------------------------------DGGT
MAB_4284c|M.abscessus_ATCC_199 HNQANIGTSTSAGGSAAVGGNAGLAG-----------------NAGLAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DSEPRRRPVLLVGSGLAVVGISAVLA---------------LEIALAIGI
Mb1485c|M.bovis_AF2122/97 GGNGANATVAGGA---------------GGAGGKGGNGGLVGNGGAGGKG
Rv1450c|M.tuberculosis_H37Rv GGNGANATVAGGA---------------GGAGGKGGNGGLVGNGGAGGKG
MMAR_5308|M.marinum_M GGDGYTSTDPTLN---------------GGAGGNGGNGGDYGNGGAGGNG
MUL_4367|M.ulcerans_Agy99 GGIGGAGGAGGTG---------------GDSGGVGGVNGDGGAGGGGGRG
Mflv_5091|M.gilvum_PYR-GCK GGKGGDADSMGS------------------AGATGGKGGNGGNGGRGGLF
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDATSMGE------------------AGATGGKGGNGGNGGRGSLF
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIH
TH_3810|M.thermoresistible__bu PGAHGESHTPGVY------------------TDRQGEDGEDGTG------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAG-------------------NAGLAGNAGLAGNAGLAGN-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 RTTGTVALQPTPN-----------------QHLIVPTEQAPAPPPVQASA
Mb1485c|M.bovis_AF2122/97 GD--GMAGVAGSSPTTAGESGTSGQNG-------------------GAGG
Rv1450c|M.tuberculosis_H37Rv GD--GMAGVAGSSPTTAGESGTSGQNG-------------------GAGG
MMAR_5308|M.marinum_M GN--GATGALGTAPPAAGDPGGNGGNG-------------------SNGG
MUL_4367|M.ulcerans_Agy99 GD--GGSSTSTSGVGGAGGAGGNGGNAGF---------------GVSAGG
Mflv_5091|M.gilvum_PYR-GCK G---------------KGGNAGNGAD----------------------GG
Mvan_1264|M.vanbaalenii_PYR-1 G---------------RGGNAGNGGN----------------------GG
MSMEG_0868|M.smegmatis_MC2_155 GSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGG
TH_3810|M.thermoresistible__bu ------------------------------------------------TG
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------AG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQ----------------------------------------------PK
Mb1485c|M.bovis_AF2122/97 AGGAGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKGGDGG
Rv1450c|M.tuberculosis_H37Rv AGGAGGRGGDFGGDGGTG---------GAGGNGANGANATTPGAKGGDGG
MMAR_5308|M.marinum_M NGGAGGTGGLIAGDGGAGGHGGGGGNGGNGAAGANGTNATISGTNGGNAG
MUL_4367|M.ulcerans_Agy99 TGGSAGDGGAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGAGIDGGAGG
Mflv_5091|M.gilvum_PYR-GCK TGGAGGAGGTGG-TGGAGGTGG-------------------TGGTGGIGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGNGGNGGTGG-TGGNGGTGG-------------------TGGTGGIGG
MSMEG_0868|M.smegmatis_MC2_155 NGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ--TDTGGNGGRGG
TH_3810|M.thermoresistible__bu IGGRGGNGGSSSGTHPMAEDGE-----------------HVKALDGRPGL
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGN-----------------AGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MAV_4827|M.avium_104 ISVPEPVAAPKPLSPPVAAPLP---------------AAPPPAAPPLPEA
Mb1485c|M.bovis_AF2122/97 HGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAGDGGN
Rv1450c|M.tuberculosis_H37Rv HGGPGAQGGNGGQGGPGGLAGNLFGQNGIQGVGGSGGKGGAGGLAGDGGN
MMAR_5308|M.marinum_M AGGNGGNGGTGGNGGAGGAAT--HGSAGANGAGGAGGNGGDGAIAGDGGT
MUL_4367|M.ulcerans_Agy99 AGGTGGAAGFPGGGGTTGAWG-TGGAGGAGGAGGAGDHGGVGVNPGDSGT
Mflv_5091|M.gilvum_PYR-GCK AGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGT
Mvan_1264|M.vanbaalenii_PYR-1 AGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGT
MSMEG_0868|M.smegmatis_MC2_155 DGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGT
TH_3810|M.thermoresistible__bu DGGNGSHGGNGGHGG----------RGGFLGIGGSGGWGGHGGNGGD---
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAGNAG----LAGNAGLAGNAGLAGNAGLAGNAGL
MLBr_01183|M.leprae_Br4923 QALTAAANTLEGLSA-----------ATVASNAAAAQLTTEIAPPAADDV
MAV_4827|M.avium_104 PPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPV
. .
Mb1485c|M.bovis_AF2122/97 GANGN-FAFGDGNGGHGGNGGN------PGAGGQGGSGGAGSTPGAKGAH
Rv1450c|M.tuberculosis_H37Rv GANGN-FAFGDGNGGHGGNGGN------PGAGGQGGSGGAGSTPGAKGAH
MMAR_5308|M.marinum_M GANGDATHFDGGNGGNGANPGI------GGLGGAGGTSGDGTTPAAHGTN
MUL_4367|M.ulcerans_Agy99 AGWAGGAGGAGGAGGSAAFNGV------NGAGGAGGNGGAGGG-GGAGAS
Mflv_5091|M.gilvum_PYR-GCK G----GDGGTGGTGGTGGTG---------GTGGTGGTGGAG---------
Mvan_1264|M.vanbaalenii_PYR-1 G----GTGGTGGTGGTGGTG---------GTGGTGGTGGAG---------
MSMEG_0868|M.smegmatis_MC2_155 GGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTA
TH_3810|M.thermoresistible__bu ------TDADGGNGGDGGNG---------GSAGRGGTGGLR---------
MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVAGNAAVAGN-------AAVGGVLNTGVSG---------
MLBr_01183|M.leprae_Br4923 S-----ILLAHFFSGHGR-----------QYQAHASQGATN---------
MAV_4827|M.avium_104 QPPVRVPQPPSPPQVGGTVPQS-----PPQHQTPPGEGTPP---------
. . .
Mb1485c|M.bovis_AF2122/97 GFTPTSG-GDGGDGGNGGHSQVVGGNGGDGGNGG-----------NGGSA
Rv1450c|M.tuberculosis_H37Rv GFTPTSG-GDGGDGGNGGNSQVVGGNGGDGGNGG-----------NGGSA
MMAR_5308|M.marinum_M GTTPTTTNGSGGRGGDGYTSTDPTLNGGKGGTGG-----------NGGDY
MUL_4367|M.ulcerans_Agy99 GIGAGVAGGDGGTGGTGG-AAGTGGAAGTGGTGG-----------AAGAA
Mflv_5091|M.gilvum_PYR-GCK -------DGTGGTGGTGG----TGGQGGQGGQGG----------------
Mvan_1264|M.vanbaalenii_PYR-1 -------DGLGGTGGTGG----TGGFGGQGGQGG----------------
MSMEG_0868|M.smegmatis_MC2_155 -----TGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGT
TH_3810|M.thermoresistible__bu ----------GVFGINGG-----NGRAGLGGRGX----------------
MAB_4284c|M.abscessus_ATCC_199 --------AIGGSSHVGG-----AINESLGGSGS----------------
MLBr_01183|M.leprae_Br4923 -----------HQDLIQS---LLTSSSAYAGTET----------------
MAV_4827|M.avium_104 --------KPDGPGNYGGGHVPTPGAGGSGGSGG-------------GHV
. . .*
Mb1485c|M.bovis_AF2122/97 GTGGNGGRGG-DGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNG
Rv1450c|M.tuberculosis_H37Rv GTGGNGGRGG-DGAFGGMSANATNPGENGPNGNPGGNGGAGGAGGAGLNG
MMAR_5308|M.marinum_M GNGGAGGNGG-NGATGTTGTNPT-PHPVTSTANPGTDASGN---QTLFNG
MUL_4367|M.ulcerans_Agy99 GSAGDGGAGG-AGGAGDDGSAGVVSGDPGTAGKAGGAGGAGGVGGNGVAG
Mflv_5091|M.gilvum_PYR-GCK -TGGTGGQGG-LGGGGGTG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -TGGTGGQGG-LGGVGGTG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT--------D
TH_3810|M.thermoresistible__bu -XXXGGGVG-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -VGGSTAVGG----------------------------------------
MLBr_01183|M.leprae_Br4923 --ANHDSL------------------------------------------
MAV_4827|M.avium_104 PTPGAGGSGG----------------------------------------
.
Mb1485c|M.bovis_AF2122/97 GNGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGG
Rv1450c|M.tuberculosis_H37Rv GNGGAGGNGGLGGFGGNGAAGANGVAVGAPGQPGGAGGHGGAGGNGGAGG
MMAR_5308|M.marinum_M GTGDNGAYAGQA--GGNGGDGYADFDQPFGGN-GGDGGIGGPGTIGGTGG
MUL_4367|M.ulcerans_Agy99 GVNGSGGAGGAGGAGGTGGAGASGVPASVDGGDGGAGGAGGAAGTGGSGG
Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG----------GTGGAGGDGGLGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG----------GTGGAGGDGGLGGLGG
MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGI--GAGGNGGDGIDGGLGG
TH_3810|M.thermoresistible__bu ----AAVRSGNGVFSGGGGT--------------PSAGFGVPTTIQFPAG
MAB_4284c|M.abscessus_ATCC_199 -GAHTGVGGGVSTGVGVGSHVGGG----------ISESLGGSGSVGGSTA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SGGGHVPTPGTGGPGGTGGSG---------------GGHVPTPGAGTPGG
Mb1485c|M.bovis_AF2122/97 NGGQGVVSDGAGGAGGAGGDGG-APGDGANGGNGQGAGAFAGGGGGRGGD
Rv1450c|M.tuberculosis_H37Rv NGGQGVVSDGAGGAGGAGGDGG-APGDGANGGNGQGAGAFAGGGGGRGGD
MMAR_5308|M.marinum_M NGGYAAIVGGWGGDGGAGGDGGGAGGNGGNGGLGLGTSALPG----QGGE
MUL_4367|M.ulcerans_Agy99 SAGN----TGAGGAGGAGGAGGSAASTGVNGDGGAGGAGGVG-----GLG
Mflv_5091|M.gilvum_PYR-GCK FGGS----GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKG-----GLF
Mvan_1264|M.vanbaalenii_PYR-1 FGGV----GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKG-----GLF
MSMEG_0868|M.smegmatis_MC2_155 NGGD----GVVNTTANAANPGSATGTATGGDGGKATGTASQG-----GNG
TH_3810|M.thermoresistible__bu -----------SCTSRAVSREGIMPSS-------RAASARAG--------
MAB_4284c|M.abscessus_ATCC_199 VGGG-------AHTGVGGGVSTGVGVGSHVGGGISESLGGSG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SGGG-----HLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGG--------
Mb1485c|M.bovis_AF2122/97 GGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGP
Rv1450c|M.tuberculosis_H37Rv GGNAGNAGAGGPGGTGSTAGKAGPAGSILHDGGNGGHGGHGAASGGNGGP
MMAR_5308|M.marinum_M GGNGGNGGAGG--GTGGTGGTGG---------------------GGFHGP
MUL_4367|M.ulcerans_Agy99 GDSAATAGGGGAGGDGGKGGAGG---------------------AGVNGV
Mflv_5091|M.gilvum_PYR-GCK G----GSGSAGKAGATGAAGASG----------------------GKGAQ
Mvan_1264|M.vanbaalenii_PYR-1 G----GSGSAGTAGVTGASGASG----------------------GKGAQ
MSMEG_0868|M.smegmatis_MC2_155 GPSWVQSGYGSTLGGNATGTATA----------------------GKGGE
TH_3810|M.thermoresistible__bu ----AACASSTSRSRRSFCCSRA---------------------------
MAB_4284c|M.abscessus_ATCC_199 -----SVGGSTAVGGGAHTGVGG----------------------GVNTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----FGGGHAPAPGGGLGGGGG------------------------HAP
Mb1485c|M.bovis_AF2122/97 GGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
Rv1450c|M.tuberculosis_H37Rv GGHGGNGGNGGTGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
MMAR_5308|M.marinum_M GGAAGDGGTGGIGATGGDGSNGGAGGAG------------GTGGLYGNGG
MUL_4367|M.ulcerans_Agy99 G--GGDGGKGGTGGAGGAGGAGSDGIIP------------SNGGLGGNGG
Mflv_5091|M.gilvum_PYR-GCK GATGAQGATG------AQGATG-ATGAA------------GKAGATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GATGAQGATG------AQGATG-ATGAS------------GAQGSAGSAG
MSMEG_0868|M.smegmatis_MC2_155 ASNGGVAGNGGNALVMAAGTTGVATGNT------------ATGGDGGAAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGSTAVG--------------GGAHTSAI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 APGGGLGGFGGGHSGGGLGGLGGGHK------------------------
Mb1485c|M.bovis_AF2122/97 NGGRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGG
Rv1450c|M.tuberculosis_H37Rv NGGRGGNGGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGGG
MMAR_5308|M.marinum_M NGGTGGTGGN-----GGTGATGGTGGDGGIGGSSEAGTAAVG-GDGGDGG
MUL_4367|M.ulcerans_Agy99 NGGNGGQAFG--------DGVGGAGGIGGKGGNAAIGTIVINGGVGGAGG
Mflv_5091|M.gilvum_PYR-GCK AAGAAGSAG-----------TTGAQGSAGTNGA---NGANGSQGAAGKAG
Mvan_1264|M.vanbaalenii_PYR-1 SAGVAGSAG-----------TTGAQGSAGTNGA---NGANGSQGAAGKAG
MSMEG_0868|M.smegmatis_MC2_155 TAGATGGAGGFSNIAAIHGAITDSTAISGHGGAG--NGGNGGKGADGWVQ
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NDALGGSGS-----------VGGSTAVGGGAHTSAINESMNSSINASHSS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 RGGDAGRGGD--AGLGGSSGPGGTPGDW-------GTGGTGGTGGTGGQG
Rv1450c|M.tuberculosis_H37Rv RGGDAGRGGD--AGLGGSSGPGGTPGDW-------GTGGTGGTGGTGGQG
MMAR_5308|M.marinum_M TGGTGGNGGN--GGDGGAAGAGGTYGQS-------GTNGTGGDAGTGG--
MUL_4367|M.ulcerans_Agy99 SGGLGGATEDGVGGVGCAGGAGGNGGRGDMLFTVGGSGGTGGDGGGGGSA
Mflv_5091|M.gilvum_PYR-GCK ATGTTGATG--------AAGEDGDAGSG------GSG-INGGAGGAGG--
Mvan_1264|M.vanbaalenii_PYR-1 ATGTTGATG--------AAGDAGDPGSE------AVD-INGGAGGAGG--
MSMEG_0868|M.smegmatis_MC2_155 AYDPAGPVGSKIANSSAVAGNGGDGGVN------GTGGASGGDGGNGGNT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SMNES---------FGSSMGSHGAAG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 AN----GGLTGGRGGTGGNGG---------AGGTGGTGHNGSQPGMGGNG
Rv1450c|M.tuberculosis_H37Rv AN----GGLTGGRGGTGGNGGNGNTGGTGGAGGTGGTGHNGSQPGMGGNG
MMAR_5308|M.marinum_M ---------SGGEGGTGGNGG---------AGGETSS----TQSPDGLSG
MUL_4367|M.ulcerans_Agy99 S--------GSGTGGSGGTGG---------VGGIGGDGKLGGFGGDGGDG
Mflv_5091|M.gilvum_PYR-GCK ---------AGGEGGEGGDGG---------KGGAGAE---------GGAG
Mvan_1264|M.vanbaalenii_PYR-1 ---------AGGEGGEGGAGG---------AGGDGSE---------GGAG
MSMEG_0868|M.smegmatis_MC2_155 SVWKSGGQTADGEHNTGGNGG---------NGGDGSEPGPGGNGA-GGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGG
Rv1450c|M.tuberculosis_H37Rv GAGGFGGNGFAGVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGG
MMAR_5308|M.marinum_M ATGAMGASGQDGIAG--------TTPGTGTGGPPAGGPDGNGGDGGPG--
MUL_4367|M.ulcerans_Agy99 GDGGFGVIGGQGGGG-----GFGGLGGTGAGGAPSD-KGINGEPGNPG--
Mflv_5091|M.gilvum_PYR-GCK GGGGAGGSGAGGAG---------GAGGSGGSGGSGGSGGSGGAAGDSDD-
Mvan_1264|M.vanbaalenii_PYR-1 GSGGAGGSGTGGAG---------GAGGSGGSGGSGGAGGSGGAAGDSD--
MSMEG_0868|M.smegmatis_MC2_155 GNGGTGGTTAGGSGN-------GGNGGNGGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------TGFEAQGHAQGHASETAHTTLPGAEHH-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
Rv1450c|M.tuberculosis_H37Rv GGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
MMAR_5308|M.marinum_M ----------------VPGP------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------