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MGSNMAEAHPVGFQWVIEAKTRGAQVIHIDPRFTRTSAVADRHVPLRAGSDIAFLGGVINYILSNDLDFR EYVTAYTNAPFLVGEDYCDAEDLDGLFSGYDHASASYDPTTWRYQPGDHADPTLQHPRCVYQILKRHYAR YTPEMVERVCGVPAQSFLQVARAWTENSGRERTTALVYSVGWTQHSMGAQFIRAGSIIQLLLGNIGRPGG GIFALRGHASIQGSTDVPTLFNLLPGYLDMPHAGQATLSDYLDNIKSRNQKGFWHNADAYMVSLLKEYWG EHATADNDYCFDYLPRINGDHSTYRTVMDMIDGKVFGYFLLGQNPAVGSAHGRMQRLGMANLDWLVVRDL VMIESATFWKEAPEVETGEISPQTCRTEVFFFPAASHVEKAGTFTQTQRMLQWREKAVDPPGDARSELWF FYHLGRKLREKLSGSTDERDRPLLQLAWDYATEGDEPSGEDVLRHMNGIDLGTGRTIDGYPSLKADGSTA CGCWIYSGVYADEVNQAARRKPRDEQRPYENEWGWTWPLNRRVLYNRASADPQGRPWSERKKLVWWDAEL GEWTGHDVPDFEKHKAPDYRPPAGAVGVEALRGDDAFVMQADGKGWLFAPSGLADGPLPTHYEPHESPVR NALYAQQGNPTRIVFGRKDNPSNPSPPEAHGEVFPFVFTAARLTEHHTAGGMSRQLPYLTELQPALFMEV SPELARMRGLTHMDWAHVITSRTAVDARVFVTDRMRPLRIEDHVVQQVWMPYHWGYTGLVEGDVVNDLLG VVLDPNVFIQESKVATCDVQPGRRPRGPALLDYIAEYRRRAGITTETGTHLDTTRDDGIAHPDPEESP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5195 | - | - | 100% (838) | formate dehydrogenase, beta subunit, selenocysteine-containing |
| M. marinum M | MMAR_3639 | fdhF | 1e-16 | 21.50% (414) | formate dehydrogenase H FdhF |
| M. marinum M | MMAR_0121 | - | 1e-05 | 24.27% (239) | formate dehydrogenase H |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1193 | narG | 3e-06 | 34.09% (88) | respiratory nitrate reductase subunit alpha NarG |
| M. gilvum PYR-GCK | Mflv_5161 | - | 4e-11 | 26.54% (211) | molybdopterin oxidoreductase |
| M. tuberculosis H37Rv | Rv1161 | narG | 3e-06 | 34.09% (88) | respiratory nitrate reductase subunit alpha NarG |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2438 | - | 7e-13 | 20.38% (417) | oxidoreductase |
| M. avium 104 | MAV_0422 | - | 0.0 | 61.57% (864) | formate dehydrogenase, alpha subunit |
| M. smegmatis MC2 155 | MSMEG_0161 | - | 2e-17 | 22.57% (421) | formate dehydrogenase, alpha subunit |
| M. thermoresistible (build 8) | TH_1885 | narX | 4e-06 | 31.82% (88) | PROBABLE NITRATE REDUCTASE NARX |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 7e-17 | 21.50% (414) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_3491 | - | 3e-11 | 19.86% (418) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3491|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1474|M.ulcerans_Agy99 -------------------------------------------------M
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW
Rv1161|M.tuberculosis_H37Rv MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW
TH_1885|M.thermoresistible__bu VTSPPRVGGPIEDLLQRSGRFFTPGDVSDDGRIVHRRGGREGDVFYRDRW
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 -----------------------MRTDAHAAGPVTVATVEGDVLHPSNQG
Mvan_3491|M.vanbaalenii_PYR-1 -----MTRTACSYCGVGCGISVETRTDP-ATGVPVIARVTGDKLHPSNFG
MUL_1474|M.ulcerans_Agy99 APNKDAVKTVCAYCGVGCGIVLQTTTDP-QTGKRRVAKSTGDKSHPANLG
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
Rv1161|M.tuberculosis_H37Rv SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
TH_1885|M.thermoresistible__bu SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 RLCTKGATHAQLMAA----------DGRMTTAHLRSIRGQQPIPAPLAAA
Mvan_3491|M.vanbaalenii_PYR-1 RLCTKGATHAEMMAAT---------DGRLTTALLRPSRDAEPVATDVDDA
MUL_1474|M.ulcerans_Agy99 RLCTKGTTTADLLAA----------PGRMESAHLRAHRAGHLESIPIDDA
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWADIQ
Rv1161|M.tuberculosis_H37Rv RGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWADIQ
TH_1885|M.thermoresistible__bu RGCPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLTDPVLAWADIQ
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 TAEAGRRLREILDNHGPDAIALYVSGQMTLEAQYLANKLAKGYIRTTHIE
Mvan_3491|M.vanbaalenii_PYR-1 LAEAGARLRAILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIE
MUL_1474|M.ulcerans_Agy99 ITQCAMRLRAIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIE
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 ADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAGFS
Rv1161|M.tuberculosis_H37Rv ADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAGFS
TH_1885|M.thermoresistible__bu ADPQRRRRYQQARGKGGLVRISWAEATEMIAAAHVHTIKTHGPDRVAGFS
MSMEG_0161|M.smegmatis_MC2_155 --------MTLLSEPDFGTPAKPGPATVTVEVDGIPVSVPEG--------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 SNSRLCMASAGTG------------------------YAQSLGADGPPGS
Mvan_3491|M.vanbaalenii_PYR-1 SNSRLCMASAGTG------------------------FKQSLGADGPPGS
MUL_1474|M.ulcerans_Agy99 SNSRLCMAGASSG------------------------YKLSLGADGPPGS
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 PIPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPE
Rv1161|M.tuberculosis_H37Rv PIPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPE
TH_1885|M.thermoresistible__bu PIPAMSMVSFAAGSRFIELLGGVMTSFYDWYADLPVASPQVFGDQTDVPE
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 YSDIEHSDLFFVIGANMADCHPILFLRMADRLSSGARLIVVDPRRTATAD
Mvan_3491|M.vanbaalenii_PYR-1 YTDFDCTDLFFVIGSNMADCHPILYLRMADRLKAGAKLIVVDPRRTATAD
MUL_1474|M.ulcerans_Agy99 YQDFDHADVFLVIGANMADCHPILFLRMMERVKSGAKLIVVDPRRTATAD
MMAR_5195|M.marinum_M ------------MGSNMAEAHPVGFQWVIEAKTRGAQVIHIDPRFTRTSA
MAV_0422|M.avium_104 ---MANADCIVIQGSNMAECHPVGFQWVEEARARGARVIHVDPRFTRTSA
Mb1193|M.bovis_AF2122/97 SGDWWDASYLVMWGSNVPITRTPDAHWMAEARYRGAKVVVVSPDYADNTK
Rv1161|M.tuberculosis_H37Rv SGDWWDASYLVMWGSNVPITRTPDAHWMAEARYRGAKVVVVSPDYADNTK
TH_1885|M.thermoresistible__bu SGDWWDAAYLMMWGSNVPVTRTPDAHWMAEVRYRGTKVVAVSPDYADNTK
MSMEG_0161|M.smegmatis_MC2_155 --------TSVMRAAAEAGIDVPKLCATDRLDAFGSCRLCLVEIDGRRGT
Mflv_5161|M.gilvum_PYR-GCK ----------MTLDATPKPLTIVRGACPHDCPDTCAMLYHVEDGKLVDVQ
: : :
MAB_2438|M.abscessus_ATCC_1997 RADLFLQITPGTDLALLNGLLHLLVEN--GAVDAEFIAQHTEGWDGMPEF
Mvan_3491|M.vanbaalenii_PYR-1 KADLYLPIRPGTDLALLNGILHLLVEN--GAVDQEFIAEHTQGWESMPEF
MUL_1474|M.ulcerans_Agy99 KADLFLQIAPGTDLALLNGLLHLIVEN--EQTDPQFISEFTEGWEVMPSF
MMAR_5195|M.marinum_M VADRHVPLRAGSDIAFLGGVINYILSN------DLDFREYVTAYTNAPFL
MAV_0422|M.avium_104 VSDRHIPIRAGSDVVLLGALINHVLTN------DLWFSEYVVAYTNAATV
Mb1193|M.bovis_AF2122/97 FADEWVRCAAGTDTALAMAMGHVILSECYVRNQVPFFVDYVRRYTDLPFL
Rv1161|M.tuberculosis_H37Rv FADEWVRCAAGTDTALAMAMGHVILSECYVRNQVPFFVDYVRRYTDLPFL
TH_1885|M.thermoresistible__bu FADEWMPCAAGTDGAMAMAMGHVILSEFFVRKQVPFFTDYVRRYTDLPFL
MSMEG_0161|M.smegmatis_MC2_155 PASCTTPVAEGMVVHTQTPKVAKLRES----VMELYISDHPLDCLTCPAN
Mflv_5161|M.gilvum_PYR-GCK GDPNHPMTRGGLCVKVKNFHEHHYQPD------RLLYPMRRVGAKGSGEF
* .
MAB_2438|M.abscessus_ATCC_1997 LAGYAPAVVAAITGLAEEDIRTAARWIG--EAREWMTLWTMGLNQSTHGT
Mvan_3491|M.vanbaalenii_PYR-1 LAGYPPDRVAAITGLSEADIRAAADMIA--EAGDWLSCWTMGLNQSTHGT
MUL_1474|M.ulcerans_Agy99 LEQFTPDRVSEITGIPSEDIRTAARWIG--TAANWMSCWTMGLNQSTHGT
MMAR_5195|M.marinum_M VGEDYCD-AEDLDGLFS---------------------------------
MAV_0422|M.avium_104 INENFRD-TEDLGGLFS---------------------------------
Mb1193|M.bovis_AF2122/97 IKLEKRG-DLLVPGKFLTAADIGEES---ENAAFKPALLDELTNTVVVPQ
Rv1161|M.tuberculosis_H37Rv IKLEKRG-DLLVPGKFLTAADIGEES---ENAAFKPALLDELTNTVVVPQ
TH_1885|M.thermoresistible__bu VKLEERD-GALVPGKMLTVADLGEVFGQHENAAFKPMLLDEATDTVTVPH
MSMEG_0161|M.smegmatis_MC2_155 GDCELQDMAGVVG-------------------------------------
Mflv_5161|M.gilvum_PYR-GCK ERITWDEALAEIKSR-----------------------------------
:
MAB_2438|M.abscessus_ATCC_1997 WNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
Mvan_3491|M.vanbaalenii_PYR-1 WNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGREMGYMGPGLPGQRS
MUL_1474|M.ulcerans_Agy99 WNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
MMAR_5195|M.marinum_M -GYDHASASYDPTTWRYQPGD-----------------------------
MAV_0422|M.avium_104 -GFDPETGQYDTSSWAYEEEDDGRSGGEIESPGGGHTHGATATHSAAGDE
Mb1193|M.bovis_AF2122/97 GSLGFRFGEDGVGKWNLDLGSVVPALSVEMDKAVNGDRSAELVTLPSFDT
Rv1161|M.tuberculosis_H37Rv GSLGFRFGEDGVGKWNLDLGSVVPALSVEMDKAVNGDRSAELVTLPSFDT
TH_1885|M.thermoresistible__bu GSLGFRYGTDGAGKWNLDLGPVVPALTVRT-----GDGPVTEVRLPCFDS
MSMEG_0161|M.smegmatis_MC2_155 -LRQVRYGYEGANHFDAEPDHSNPYFDFDPSKCIACSRCVRACGEIQGTF
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 VKSPADRDFVEKRWQLPPGSIRAEFGTGTVDMFAQMAAGNIKACWIICTN
Mvan_3491|M.vanbaalenii_PYR-1 VASAADRAFVEEQWDLEPGTIRADIGPGTVEMFRQMGSGDIKAAWIICTN
MUL_1474|M.ulcerans_Agy99 VLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRMADGEIKACWIICSN
MMAR_5195|M.marinum_M -------------HADPTLQHPRCVYQILKRHYAR---------------
MAV_0422|M.avium_104 HGSGGPPLAHARVRRDETLQHPRTVFQILKRHYAR---------------
Mb1193|M.bovis_AF2122/97 IDGHGETVSRGLPVRRAGKHLVCTVFDLMLAHYGVARAGLPGEWPTGYHD
Rv1161|M.tuberculosis_H37Rv IDGHGETVSRGVPVRRAGKHLVCTVFDLMLAHYGVARAGLPGEWPTGYHD
TH_1885|M.thermoresistible__bu VDGHGTTVTRGVPVRHVGDHRVCTVFDLMLAQYGVSRPGLPGDWPTGYDD
MSMEG_0161|M.smegmatis_MC2_155 ALTIEGRGFESKVSPGAGELFMDSECVSCGACVQACPTATLQERSVVELG
Mflv_5161|M.gilvum_PYR-GCK --------WTEIIDTYGSQAIMPHAYLGHQGVLNG---------------
MAB_2438|M.abscessus_ATCC_1997 -PVASVANRKNVVDGLRRAELVIAQDAFLATATNEYADILLPAALWAESD
Mvan_3491|M.vanbaalenii_PYR-1 -PVASVANRDAVVAGLSTAELVITQDVYADTATNRYADIVLPATLWAETD
MUL_1474|M.ulcerans_Agy99 -PVATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESD
MMAR_5195|M.marinum_M ----YTPEMVERVCGVPAQSFLQVARAWTENSGRER-TTALVYSVGWTQH
MAV_0422|M.avium_104 ----YTPEMVKDVCGISREDFDYLARSIVENSGRER-TTCFAYAVGWTQH
Mb1193|M.bovis_AF2122/97 RTQQNTPAWQESITGVPAAQAIRFAKEFARNATESGGRSMIIMGGGICHW
Rv1161|M.tuberculosis_H37Rv RTQQNTPAWQESITGVPAAQAIRFAKEFARNATESGGRSMIIMGGGICHW
TH_1885|M.thermoresistible__bu ATRPYTPAWQEPITGVSAAQVIRIATEFARNAEESGGRSMIIMGAGICQW
MSMEG_0161|M.smegmatis_MC2_155 IPTRSVTTTCAYCGVGCSFKAELRGDELVRMVPQKAGGANEGHSCVKGRF
Mflv_5161|M.gilvum_PYR-GCK --------LTSGDAFFNRLGSTVAEKTYCESGSSTAWHMTVGGSGGLDVE
MAB_2438|M.abscessus_ATCC_1997 GVSINSERTATLTNRAVEAPGDARPDWQLICDIATAMGFGDAFGYSSSEE
Mvan_3491|M.vanbaalenii_PYR-1 AVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHLGFGDAFDYKSSEQ
MUL_1474|M.ulcerans_Agy99 GVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMGFSESFSYSSAAE
MMAR_5195|M.marinum_M SMGAQFIRAGSIIQLLLGNIGRPGGG---------IFALRGHASIQGSTD
MAV_0422|M.avium_104 TLGAQFIRTATILQLLMGNVGRPGSG---------IMALRGHATIQGSTD
Mb1193|M.bovis_AF2122/97 FHSDVMYRSVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGWQTMAMATD
Rv1161|M.tuberculosis_H37Rv FHSDVMYRSVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGWQTMAMATD
TH_1885|M.thermoresistible__bu FHGDATYRAVLALLLLTGSMGRNGGGWAHYVGQEKCRPVTGWATMAMATD
MSMEG_0161|M.smegmatis_MC2_155 AFGYATHPDRVLRPMVRDKITDPWREVEWDEAINTVARRMQEIAQRHGAG
Mflv_5161|M.gilvum_PYR-GCK SMAHSKYIIVWGMNMTSTNLHG------------WPFLLEARKNNGAKIV
MAB_2438|M.abscessus_ATCC_1997 IFEEIRAFWNPRTGYDMRGMSYARLRQGPVQWPCPPESEVDRNPIRYLND
Mvan_3491|M.vanbaalenii_PYR-1 IFDEIRRFHNPGTGYDLRGITYERLRDTPVQWPCASAEQSDRNPIRYLND
MUL_1474|M.ulcerans_Agy99 VFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDGASNRSPIRYLND
MMAR_5195|M.marinum_M VPTLFN---------LLPG----YLDMPHAG-QATLSDYLDN------IK
MAV_0422|M.avium_104 IPTLFN---------LLPG----YLPMPKAGVHDTLADYLDA------VG
Mb1193|M.bovis_AF2122/97 WSRPPR---------QVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFA
Rv1161|M.tuberculosis_H37Rv WSRPPR---------QVPGASYWYAHTDQWRYDGYGADKLASPVGRGRFA
TH_1885|M.thermoresistible__bu WSRPPR---------QMPGTSYWYVHTDQWNYDGYRADALASPIGRGRFR
MSMEG_0161|M.smegmatis_MC2_155 AIGAITS--------SRCTNEEVYVVQKMVRAAFGNNNVDTCARVCHSPT
Mflv_5161|M.gilvum_PYR-GCK VIDPVKN--------RTARQADWHIPIRPGTDGALAMGMIQQIIAQGLVD
MAB_2438|M.abscessus_ATCC_1997 GISQHPHVDENGVVPRLAFPTPSRRAVFHARAHRDPAELPGEGYPVVLNT
Mvan_3491|M.vanbaalenii_PYR-1 GVSQDQYVGPDGHRPRLAFPTPSRRAVFHPRPHMDAAELPDDDYPLVLNT
MUL_1474|M.ulcerans_Agy99 GVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDEMPDGDYPFLLNT
MMAR_5195|M.marinum_M SRNQKGFWHNADAYMVSLLKEYWG-------EHATADNDYCFDYLPRING
MAV_0422|M.avium_104 SKKQKGFWANADAYTVSLLKAWWG-------EAATADNDWAYDYLPRLTG
Mb1193|M.bovis_AF2122/97 GKHTMDLLTSATAMGWSPFYPQFDRSSLDVADEARAAGRDVGDYVAEQLA
Rv1161|M.tuberculosis_H37Rv GKHTMDLLTSATAMGWSPFYPQFDRSSLDVADEARAAGRDVGDYVAEQLA
TH_1885|M.thermoresistible__bu GKHTMDVLASATAMGWSPFYPQFDRSSLDIADEARAAGKEIGAYVCEQLA
MSMEG_0161|M.smegmatis_MC2_155 GYGLKQTFGESAGTQDFRSVAEADVIVVIGANPTDGHPVFASRMKQRIRE
Mflv_5161|M.gilvum_PYR-GCK TDYVERYTVGYDELAERAAQYPPERVEEITGIPADDIRKLAYEYATSQPA
MAB_2438|M.abscessus_ATCC_1997 GRLQHHWHTLTKTGRIKTLDRLHPSPFVEIHPHDATTLGISDGDIVEIAS
Mvan_3491|M.vanbaalenii_PYR-1 GRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAAALGISGGHDVELVT
MUL_1474|M.ulcerans_Agy99 GRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADMQICEGDHIEIAS
MMAR_5195|M.marinum_M -------DHSTYRTVMDMIDG-------KVFGYFLLGQNPAVGSAHGRMQ
MAV_0422|M.avium_104 -------PHGTYQTVMGMLAD-------EVEGYFLLGQNPAVGSAHGRMQ
Mb1193|M.bovis_AF2122/97 -------QHKLKLSITDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHL
Rv1161|M.tuberculosis_H37Rv -------QHKLKLSITDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHL
TH_1885|M.thermoresistible__bu -------SGGLKLAVTDPDDPRNWPRVLSVWRSNLLGSSSKGNEYFLRHL
MSMEG_0161|M.smegmatis_MC2_155 G------------ARLVVVD--------PRRIDLVRSPHIEADHHLQLRP
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------AIRQGVALERSR
.
MAB_2438|M.abscessus_ATCC_1997 RRGTAELPALVSDRVKRGSCFAPFHWNDAHGPGLTINAVTNDAVDPDSLQ
Mvan_3491|M.vanbaalenii_PYR-1 RRGRAVLPAVLTDRVQPGNTWVPFHWNDEHGDHLTVNALTNDAVDPDSLQ
MUL_1474|M.ulcerans_Agy99 RRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINAVTNDAVDPISRQ
MMAR_5195|M.marinum_M RLGMANLDWLVVRDLVMIESAT--FWKEAPE-------VETGEISPQTCR
MAV_0422|M.avium_104 RLGMSHLKWLVVRDFNLIESAT--WWKDGPE-------IASGELKTEEIE
Mb1193|M.bovis_AF2122/97 LGTDSNVQSDPPTDGVHPRDVV--WDSDIPEGKLDLIMSIDFRMTSTTLV
Rv1161|M.tuberculosis_H37Rv LGTDSNVQSDPPTDGVHPRDVV--WDSDIPEGKLDLIMSIDFRMTSTTLV
TH_1885|M.thermoresistible__bu LGTDSNLRATRTPEALRPNDVR--SPDEIPEGKLDLLMSIDFRMTSTTLL
MSMEG_0161|M.smegmatis_MC2_155 GTNVAVVNAMAHVVVTEGLTDASFVAERCEGFEEWAEFIAREENSPEAVE
Mflv_5161|M.gilvum_PYR-GCK GGGQAIRAITCLPALVG-------AWRHVGGGTMEMPIWEFPTKFDAICK
:
MAB_2438|M.abscessus_ATCC_1997 PEFKVSAVALRPTGR-----------------------------------
Mvan_3491|M.vanbaalenii_PYR-1 PEFKVCAVRLAPVPA-----------------------------------
MUL_1474|M.ulcerans_Agy99 PEYKACAVTLTKVARPQLQPEPGEPADACADATAPKLLADTAQFSVTQVD
MMAR_5195|M.marinum_M TEVFFFPAASHVEKA-----------------------------------
MAV_0422|M.avium_104 TEVFFLPAATHVEKA-----------------------------------
Mb1193|M.bovis_AF2122/97 SDVVLPAATWYEKSD-----------------------------------
Rv1161|M.tuberculosis_H37Rv SDVVLPAATWYEKSD-----------------------------------
TH_1885|M.thermoresistible__bu SDIVLPAATWYEKHD-----------------------------------
MSMEG_0161|M.smegmatis_MC2_155 PITGVPAEELRAAAR-----------------------------------
Mflv_5161|M.gilvum_PYR-GCK PEWIPEGTRVVNELD-----------------------------------
.
MAB_2438|M.abscessus_ATCC_1997 ----------TKADSMPEKQKEALG-------------------------
Mvan_3491|M.vanbaalenii_PYR-1 ----------AGAPEFTETEKLYLAGFFAGIEEGL----PGVPVLPASAP
MUL_1474|M.ulcerans_Agy99 ALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGRRMAGVSTLPISSP
MMAR_5195|M.marinum_M -------------GTFTQTQR-----------------------------
MAV_0422|M.avium_104 -------------GSFTQTQR-----------------------------
Mb1193|M.bovis_AF2122/97 -------------LSSTDMHP-----------------------------
Rv1161|M.tuberculosis_H37Rv -------------LSSTDMHP-----------------------------
TH_1885|M.thermoresistible__bu -------------LSSTDMHP-----------------------------
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------D
Mvan_3491|M.vanbaalenii_PYR-1 VGPRARLWVDGLLAGRYSRSDTVAETPA-------------------TEG
MUL_1474|M.ulcerans_Agy99 FDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQSDNAAEAAVEQPP
MMAR_5195|M.marinum_M --------------------------------------------------
MAV_0422|M.avium_104 --------------------------------------------------
Mb1193|M.bovis_AF2122/97 --------------------------------------------------
Rv1161|M.tuberculosis_H37Rv --------------------------------------------------
TH_1885|M.thermoresistible__bu --------------------------------------------------
MSMEG_0161|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5161|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 VAILWTSQTGNAETAAVSVHRLLHTAGISATITAMDECDPADLVGVNTAV
Mvan_3491|M.vanbaalenii_PYR-1 PLVLWASQTGNAEEFAGRLGERLN----GARLRAMDDVELDDLSEAGEVV
MUL_1474|M.ulcerans_Agy99 IVVLWASQTGTAEELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQRLL
MMAR_5195|M.marinum_M ---MLQWREKAVDPPGDARSELWFFYHLGRKLREKLSGSTDERDRPLLQL
MAV_0422|M.avium_104 ---LVQWRHQAVEPPGQCQSELQFFYELGKRIRQRLAGSTDERDRPLLDL
Mb1193|M.bovis_AF2122/97 ---YVHSFSPAIDPPWETRSDFGAFAAIARAFSALAKRHLGTRTDVVLTA
Rv1161|M.tuberculosis_H37Rv ---YVHSFSPAIDPPWETRSDFDAFAAIARAFSALAKRHLGTRTDVVLTA
TH_1885|M.thermoresistible__bu ---YVHAFSPAIDPPWETRSDYDAFGAIARAFSALARKHLGTRTDVVLGA
MSMEG_0161|M.smegmatis_MC2_155 ---LYALAPNAAIYYGLGVTEHSQGSTMVMGMANLAMACGNIGRDGVGVN
Mflv_5161|M.gilvum_PYR-GCK ---LGMALTGEMELDPPIKSLFVYNSNPVSQGPAQEKTMRGLMRDDLFTV
MAB_2438|M.abscessus_ATCC_1997 VIASSFGEGGPPDNGARFWAALSGDTKP-LNHMRYAVLGFGDRAYADFCG
Mvan_3491|M.vanbaalenii_PYR-1 IVTSTFGDGGPPDNGAGFWERLESPHAPSLDGVRYTVLGIGDRSYDNFCG
MUL_1474|M.ulcerans_Agy99 LVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGTRYSVLALGDSNYADFCG
MMAR_5195|M.marinum_M AWDYATEGD-EPSGEDVLRHMNGI--DLGT-GRTIDGYPSLKADGSTACG
MAV_0422|M.avium_104 TWDYPTDEHGDPDGEAVLAEINGY--RVGEPADPLASYTELRADGSTAAG
Mb1193|M.bovis_AF2122/97 LQHDTPDEMAYPDGTERDWLATG---EVPVPGRTMSKLTVVERDYTAIYD
Rv1161|M.tuberculosis_H37Rv LQHDTPDEMAYPDGTERDWLATG---EVPVPGRTMSKLTVVERDYTAIYD
TH_1885|M.thermoresistible__bu LQHDTPGAMAYAGGTERDWRVTG---EVPVPGKTIGPLAVVERDYTAIAD
MSMEG_0161|M.smegmatis_MC2_155 PLRGQNNVQGSCDMGS---------FPHELPGYRHVSDDAVRQVFENLWG
Mflv_5161|M.gilvum_PYR-GCK VSEH-----------------------FVTDTAKFADLLLPATMQAEQLD
.
MAB_2438|M.abscessus_ATCC_1997 HAKALDARLHELGASPLLGRVDGEATDRTLVASWTADLLDAIGDGATAIV
Mvan_3491|M.vanbaalenii_PYR-1 HARSLDARLADLGATRMLDRVECEAYDAQPLARWADSVVELVAAPGTPPA
MUL_1474|M.ulcerans_Agy99 HGRALDHRLAELGASRITDRVDCEPDYEESAARWLQEVLDGLRRTAPPVI
MMAR_5195|M.marinum_M CWIYSGVYADEVNQAARRKPRDEQRPYENEWG------------------
MAV_0422|M.avium_104 CWIYTGVYANAVNQAARRVPNGGASPSQSEWG------------------
Mb1193|M.bovis_AF2122/97 KWLTLGPLIDQFGMTTKGYTVHPFREVS----------------------
Rv1161|M.tuberculosis_H37Rv KWLTLGPLIDQFGMTTKGYTVHPFREVS----------------------
TH_1885|M.thermoresistible__bu KWAALGPLVEELGVTTKGVTTWPVQEVA----------------------
MSMEG_0161|M.smegmatis_MC2_155 TELLAEPGLRIPNMFDAAIEGSFR--------------------------
Mflv_5161|M.gilvum_PYR-GCK IMVTWGHLYISLNQPAIAPPGECVPN------------------------
.
MAB_2438|M.abscessus_ATCC_1997 ETVRKLRSEGLRVAAPERFTRDAPILAALSHNELLSAPNSGKEVRRIEFD
Mvan_3491|M.vanbaalenii_PYR-1 APA----------QEPTLFTRAEPVAAPLCRNTRLTPQGAAKEVRQIGFD
MUL_1474|M.ulcerans_Agy99 TAEPVRAAS--IASRPQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFR
MMAR_5195|M.marinum_M --------------------------WTWPLNRRVLYNRASADPQGRPWS
MAV_0422|M.avium_104 --------------------------WAWPADRRVLYNRASADPDGKPWS
Mb1193|M.bovis_AF2122/97 ---------------------------ELAANFGVMNSGVAVGRPAITTA
Rv1161|M.tuberculosis_H37Rv ---------------------------ELAANFGVMNSGVAVGRPAITTA
TH_1885|M.thermoresistible__bu ---------------------------ELAKAFGVMDSGPAAGRPAITTA
MSMEG_0161|M.smegmatis_MC2_155 --------------------------GLFVHGEDIAQSDPNVKHVLAALE
Mflv_5161|M.gilvum_PYR-GCK ----------------------------VELFRRLAHVMEFDDESMAYWN
:
MAB_2438|M.abscessus_ATCC_1997 LTGHDVSYSAGDALGIYPTNREEDVQRWLTTTGFDAQLPVTIDGG-ELPL
Mvan_3491|M.vanbaalenii_PYR-1 ISAHDVTYSVGDSLGVCVVNSDFVVENWLAATDLRGDEAVVVDGV-QQAL
MUL_1474|M.ulcerans_Agy99 VPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTRLDGHTEVEVAGHGTMSL
MMAR_5195|M.marinum_M ERKKLVWWDAELGE-----WTGHDVPDFEKHKAPDYRPPAGAVGV-----
MAV_0422|M.avium_104 ERKRYIWWDPDQRR-----WVGYDVPDFVVDRAPGARPDPELGGP-----
Mb1193|M.bovis_AF2122/97 KRMADVILALSGTC-----NGRLAVEGFLELEKRTGQRLAHLAEG-----
Rv1161|M.tuberculosis_H37Rv KRMADVILALSGTC-----NGRLAVEGFLELEKRTGQRLAHLAEG-----
TH_1885|M.thermoresistible__bu ARMAEVILALSGTS-----NGRLAVEGFRELEKRTGQRLAQLAEG-----
MSMEG_0161|M.smegmatis_MC2_155 SMELVVVQDLFLNETSKYAHVFLPGASFLEKDGTFTNAERRINRVRAVMK
Mflv_5161|M.gilvum_PYR-GCK RTDREMLIDFHDWD-----------------------------------A
:
MAB_2438|M.abscessus_ATCC_1997 ATALANHYDICRVTEDLLRFIAERRRDKHSA----KLLQGRDTQAREVWL
Mvan_3491|M.vanbaalenii_PYR-1 RDALTAHYDVCKVTSNLVKFVAEHCRDAATA----KRLRN-DRGELDRWL
MUL_1474|M.ulcerans_Agy99 RAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWT
MMAR_5195|M.marinum_M EALRGDDAFVMQADGKGWLFAPSGLADGPLPTHYEPHESPVRNALYAQQG
MAV_0422|M.avium_104 DALAGDDPFIMQADGKGWLFAPKGVVDGPLPTHYEPQESPVANALYPQQR
Mb1193|M.bovis_AF2122/97 SEERRITYADTQARPVPVITSPEWSGSESGGRRYAPFTINIEHLKPFHTL
Rv1161|M.tuberculosis_H37Rv SEERRITYADTQARPVPVITSPEWSGSESGGRRYAPFTINIEHLKPFHTL
TH_1885|M.thermoresistible__bu SEERRITFADTQARPVPVITSPEWSGSETAGRRYAPFTVNIEHLKPFHTL
MSMEG_0161|M.smegmatis_MC2_155 PKSGMHEWDIVCRIATAMGYPMHYDHPSQIMDEIATLTPTFTGVSFDKLD
Mflv_5161|M.gilvum_PYR-GCK PALAGITYEKLEEVGWMRLAVGTPDVRAPHAEGNFPTPSGKCEFKSSLAE
MAB_2438|M.abscessus_ATCC_1997 RGRNALDVIREFPIRAAIEEWQQVLIRLTPRQYSISSSPLVSPQAISLTV
Mvan_3491|M.vanbaalenii_PYR-1 VNRNGLDLVREFSVRADPQLWQEVLVRLTPRQYSISSSPLVSPNEVQLTV
MUL_1474|M.ulcerans_Agy99 WGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTV
MMAR_5195|M.marinum_M NPTRIVFGRKDNPSNPSPPEAHGEVFPFVFTAARLTEHHTAG----GMSR
MAV_0422|M.avium_104 NPARITFARKDNLSAPSAGEPGSDVYPYVFTTYRLTEHHTAG----GMSR
Mb1193|M.bovis_AF2122/97 TGRMHFYLAHDWVEELGEQLP---VYRPPLDMARLFNQPELGPTDDGLGL
Rv1161|M.tuberculosis_H37Rv TGRMHFYLAHDWVEELGEQLP---VYRPPLDMARLFNQPELGPTDDGLGL
TH_1885|M.thermoresistible__bu TGRMHFYLDHDWLEELGEQLP---VYRPPLDMARLFGAQQIG-HSDGVGL
MSMEG_0161|M.smegmatis_MC2_155 QLG---SIQWPCDEEAPEGTPIMHVDAFTRGLGRFVPTPFVPTDERSTRR
Mflv_5161|M.gilvum_PYR-GCK GGNFVVPVWRSMYEGMQPGGYVDPVPDYVPPFESPQSNPELA------QR
:
MAB_2438|M.abscessus_ATCC_1997 SIVRYQGPDGSPRGGVGSTFLADRAQHLPVPIFLQRSPHFRPPRTSDTPM
Mvan_3491|M.vanbaalenii_PYR-1 SVVRYRGADGGPRGGVASTYLADLPDGTAVPVFLQRSPHFRPPQDSHTPM
MUL_1474|M.ulcerans_Agy99 SPVRYN-FQGVPRRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPM
MMAR_5195|M.marinum_M QLPYLTELQPALFMEVSPELARMRG------LTHMDWAHVITSRTAVDAR
MAV_0422|M.avium_104 WLPYLSELQPEMFCEVSPELAAERG------LQPYGWATIISPRAAIEAR
Mb1193|M.bovis_AF2122/97 TVRYLTPHSKWSFHSTYQDNLYMLS------LSRGGPTMWMSPGDAAKIN
Rv1161|M.tuberculosis_H37Rv TVRYLTPHSKWSFHSTYQDNLYMLS------LSRGGPTMWMSPGDAAKIN
TH_1885|M.thermoresistible__bu TVRYLTPHSKWSIHSEYQDNLLMLS------LSRGGPTMWMSPADAAKIG
MSMEG_0161|M.smegmatis_MC2_155 FPLILTTGRILSQYNVGAQTRRTAN-----IAWHAEDVLEIHPHDAEVRG
Mflv_5161|M.gilvum_PYR-GCK YPLSIISPKPHAFLNSQYGNAADKQ------KVQGGQRVFIHPADAAERG
. .
MAB_2438|M.abscessus_ATCC_1997 IMIGPGTGIAPFRGFLQERRALGHTGANWLFFGDQHRTEHFYYRDELDGF
Mvan_3491|M.vanbaalenii_PYR-1 IMVGPGTGIAPFRGFLQERRALGHRGPNWLFFGDQHRAQNFYYRDDLQDM
MUL_1474|M.ulcerans_Agy99 IMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAM
MMAR_5195|M.marinum_M VFVTDRMRPLRIEDHVVQQVWMPYHWG---------YTG--LVEGDVVN-
MAV_0422|M.avium_104 VLVTKRVAPLVINGHTVHQIGLPYHWG---------VGGDAVVSGDAAN-
Mb1193|M.bovis_AF2122/97 VRDNDWVEAVNANGIYVCRAIVSHRMP---------EGVVFVYHVQERTV
Rv1161|M.tuberculosis_H37Rv VRDNDWVEAVNANGIYVCRAIVSHRMP---------EGVVFVYHVQERTV
TH_1885|M.thermoresistible__bu VADNDWVEAVNPNGVLVCRAIVSHRMP---------EGVVYVYHVQERTI
MSMEG_0161|M.smegmatis_MC2_155 IADGDLVTLASRVGETTLHAQTSDRMP-----------------------
Mflv_5161|M.gilvum_PYR-GCK IAEGDVVRVFNDRGSFQGPAAYDDGLMAG---------------------
: .
MAB_2438|M.abscessus_ATCC_1997 LRDGSLRRLDLAFSRDQAKRIYVQHRMMEQGAQLWRWLNEGAHLYVCGDA
Mvan_3491|M.vanbaalenii_PYR-1 VDDGFLNRLDLAFSRDQARRVYVQHKMLDYGADVWRWLDDGAHFYVCGDA
MUL_1474|M.ulcerans_Agy99 HRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTA
MMAR_5195|M.marinum_M DLLGVVLDPNVFIQESKVATCDVQPGRRPRGPALLDYIAE--YRRRAGIT
MAV_0422|M.avium_104 DLLGVTLDPNVQIQESKAGSCDIRPGRRPRGEELLRLIAD--YQSRSGVT
Mb1193|M.bovis_AF2122/97 DTPRTETNGKRGGNHNALTRVRIKPSHLAGGYGQHAFAFN--YLGPTGNQ
Rv1161|M.tuberculosis_H37Rv DTPRTETNGKRGGNHNALTRVRIKPSHLAGGYGQHAFAFN--YLGPTGNQ
TH_1885|M.thermoresistible__bu DVPIAETTGKRGGIHNSLTRLLIKPSHLAGGYAQNAFAFN--YLGPTGNQ
MSMEG_0161|M.smegmatis_MC2_155 ---TGVVYTTFHYPVTGANVVTTDSSDWATNCPEYKVTAVQVALAPPSAR
Mflv_5161|M.gilvum_PYR-GCK -----LVMANVGHWQGKTSGTTVNAITADRHCGLGNAGVYGDNLVEVEKV
MAB_2438|M.abscessus_ATCC_1997 SRMAKDVDGALLTIAQKHGKLSGEQALEFRKELVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1 TRMAGDVDDALTEIIRTHGGMSADAARDYKREMVAEKRYVRDVY
MUL_1474|M.ulcerans_Agy99 DPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADKRYHRDVY
MMAR_5195|M.marinum_M TETGTHLDTTRDDGIAHPDPEESP--------------------
MAV_0422|M.avium_104 AETG---NVRVDDAVWERGS------------------------
Mb1193|M.bovis_AF2122/97 RDEVTVVRRRSQEVRY----------------------------
Rv1161|M.tuberculosis_H37Rv RDEVTVVRRRSQEVRY----------------------------
TH_1885|M.thermoresistible__bu RDEVTVVRRRSQRVVF----------------------------
MSMEG_0161|M.smegmatis_MC2_155 QAEARVDELPETELVR----------------------------
Mflv_5161|M.gilvum_PYR-GCK AEEAFEDREAS---------------------------------