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VRTDAHAAGPVTVATVEGDVLHPSNQGRLCTKGATHAQLMAADGRMTTAHLRSIRGQQPIPAPLAAATAE AGRRLREILDNHGPDAIALYVSGQMTLEAQYLANKLAKGYIRTTHIESNSRLCMASAGTGYAQSLGADGP PGSYSDIEHSDLFFVIGANMADCHPILFLRMADRLSSGARLIVVDPRRTATADRADLFLQITPGTDLALL NGLLHLLVENGAVDAEFIAQHTEGWDGMPEFLAGYAPAVVAAITGLAEEDIRTAARWIGEAREWMTLWTM GLNQSTHGTWNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVKSPADRDFVE KRWQLPPGSIRAEFGTGTVDMFAQMAAGNIKACWIICTNPVASVANRKNVVDGLRRAELVIAQDAFLATA TNEYADILLPAALWAESDGVSINSERTATLTNRAVEAPGDARPDWQLICDIATAMGFGDAFGYSSSEEIF EEIRAFWNPRTGYDMRGMSYARLRQGPVQWPCPPESEVDRNPIRYLNDGISQHPHVDENGVVPRLAFPTP SRRAVFHARAHRDPAELPGEGYPVVLNTGRLQHHWHTLTKTGRIKTLDRLHPSPFVEIHPHDATTLGISD GDIVEIASRRGTAELPALVSDRVKRGSCFAPFHWNDAHGPGLTINAVTNDAVDPDSLQPEFKVSAVALRP TGRTKADSMPEKQKEALGDVAILWTSQTGNAETAAVSVHRLLHTAGISATITAMDECDPADLVGVNTAVV IASSFGEGGPPDNGARFWAALSGDTKPLNHMRYAVLGFGDRAYADFCGHAKALDARLHELGASPLLGRVD GEATDRTLVASWTADLLDAIGDGATAIVETVRKLRSEGLRVAAPERFTRDAPILAALSHNELLSAPNSGK EVRRIEFDLTGHDVSYSAGDALGIYPTNREEDVQRWLTTTGFDAQLPVTIDGGELPLATALANHYDICRV TEDLLRFIAERRRDKHSAKLLQGRDTQAREVWLRGRNALDVIREFPIRAAIEEWQQVLIRLTPRQYSISS SPLVSPQAISLTVSIVRYQGPDGSPRGGVGSTFLADRAQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGT GIAPFRGFLQERRALGHTGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRLDLAFSRDQAKRIYVQHRM MEQGAQLWRWLNEGAHLYVCGDASRMAKDVDGALLTIAQKHGKLSGEQALEFRKELVAEKRYVRDVY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2438 | - | - | 100% (1257) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2485c | - | e-108 | 42.28% (544) | sulfite reductase |
| M. abscessus ATCC 19977 | MAB_2492 | - | e-103 | 42.70% (534) | sulfite reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2924c | fdhF | 6e-25 | 25.34% (446) | formate dehydrogenase H |
| M. gilvum PYR-GCK | Mflv_3016 | - | 0.0 | 59.97% (1314) | molybdopterin oxidoreductase |
| M. tuberculosis H37Rv | Rv2900c | fdhF | 6e-25 | 25.34% (446) | formate dehydrogenase H |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3639 | fdhF | 0.0 | 63.97% (730) | formate dehydrogenase H FdhF |
| M. avium 104 | MAV_2075 | - | 0.0 | 70.11% (696) | FdhF protein |
| M. smegmatis MC2 155 | MSMEG_2837 | - | 2e-96 | 33.38% (722) | nitrate reductase NarB |
| M. thermoresistible (build 8) | TH_4553 | - | 5e-60 | 70.99% (162) | PUTATIVE sulfite reductase (NADPH) alpha subunit |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 0.0 | 64.11% (730) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_3491 | - | 0.0 | 60.50% (1309) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3016|M.gilvum_PYR-GCK -------------------------------------------MTRTACS
Mvan_3491|M.vanbaalenii_PYR-1 -------------------------------------------MTRTACS
TH_4553|M.thermoresistible__bu ----------------------------------VATGRGGADCVRTACS
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------MRTDAH
MMAR_3639|M.marinum_M -------------------------------------MAPNKDAVKTVCA
MUL_1474|M.ulcerans_Agy99 -------------------------------------MAPNKDAVKTVCA
MAV_2075|M.avium_104 --------------------------------------------MNTMCA
Mb2924c|M.bovis_AF2122/97 MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQ
Rv2900c|M.tuberculosis_H37Rv MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQ
MSMEG_2837|M.smegmatis_MC2_155 ----------MARTDRISDPWGSRTPYAAGEPWPQRVDRYLTPGLTDDDV
Mflv_3016|M.gilvum_PYR-GCK YCGVGCGISVETRTDPASGVPVIARVSGDKLHPTNFGRLCTKGATHAEMM
Mvan_3491|M.vanbaalenii_PYR-1 YCGVGCGISVETRTDPATGVPVIARVTGDKLHPSNFGRLCTKGATHAEMM
TH_4553|M.thermoresistible__bu YCGVGCGIEVRTTPGPAG--PVIAGVAGDPLHPTNRGRLCTKGATHAELM
MAB_2438|M.abscessus_ATCC_1997 AAGP----------------VTVATVEGDVLHPSNQGRLCTKGATHAQLM
MMAR_3639|M.marinum_M YCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLL
MUL_1474|M.ulcerans_Agy99 YCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLL
MAV_2075|M.avium_104 YCGVGCGMVLQITTDPQTGRRHVAKSVGNKEHPANFGRLCTKGATTADLL
Mb2924c|M.bovis_AF2122/97 QMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEE
Rv2900c|M.tuberculosis_H37Rv QMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEE
MSMEG_2837|M.smegmatis_MC2_155 DRWVQSAAVLHSNGDGLDIAVKDGRIVGVRGRADDRVNHGRLDPKDLFGW
. . . ...
Mflv_3016|M.gilvum_PYR-GCK AATDGRLTTALVRPSRDADPVALDVDDAVAEAGSRLRAIVDEHG------
Mvan_3491|M.vanbaalenii_PYR-1 AATDGRLTTALLRPSRDAEPVATDVDDALAEAGARLRAILDEHG------
TH_4553|M.thermoresistible__bu GSTKGRALTALIRPRRGEPPVPAPVDDAVAAAGQRLRAILDTHG------
MAB_2438|M.abscessus_ATCC_1997 AA-DGRMTTAHLRSIRGQQPIPAPLAAATAEAGRRLREILDNHG------
MMAR_3639|M.marinum_M AA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG------
MUL_1474|M.ulcerans_Agy99 AA-PGRMESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG------
MAV_2075|M.avium_104 AA-PGRMDSAHARAGRGEPLEPIGTDQAITRCAKQLRAIIDEHG------
Mb2924c|M.bovis_AF2122/97 AT--KRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRP
Rv2900c|M.tuberculosis_H37Rv AT--KRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRP
MSMEG_2837|M.smegmatis_MC2_155 QANHARDRLRTPLIRQDGVLVESDWDTAMDRIVARSRQLLDERG------
: * : : :: *
Mflv_3016|M.gilvum_PYR-GCK -------------------PDAVALYVSGQMSIEAQYLATKLAKGFLRTV
Mvan_3491|M.vanbaalenii_PYR-1 -------------------PDAVALYVSGQMSIEAQYLATKLAKGFLRTV
TH_4553|M.thermoresistible__bu -------------------PDAIALYVSGQLSLEAQYLATKLAKGFIRTA
MAB_2438|M.abscessus_ATCC_1997 -------------------PDAIALYVSGQMTLEAQYLANKLAKGYIRTT
MMAR_3639|M.marinum_M -------------------PDAVGVYVSGQMSIEAQYLANKLTKGFIGTN
MUL_1474|M.ulcerans_Agy99 -------------------PDAVGVYVSGQMSIEAQYLANKLTKGFIGTK
MAV_2075|M.avium_104 -------------------PDAFAMYVSGQMSLEAQYLANKLTKGFIGTN
Mb2924c|M.bovis_AF2122/97 ISWDAAYQLIAEQLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFG-TN
Rv2900c|M.tuberculosis_H37Rv ISWDAAYQLIAEQLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFG-TN
MSMEG_2837|M.smegmatis_MC2_155 -------------------PNSIGFYTSGQLFLEEYYTQCVIAHGAIGTN
*: .*.**: * : :.:. *
Mflv_3016|M.gilvum_PYR-GCK HIESNSRLCMASAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGSNMADCH
Mvan_3491|M.vanbaalenii_PYR-1 HIESNSRLCMASAGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCH
TH_4553|M.thermoresistible__bu HLEANSRLCMASAASGYKQSLGADGPPGSYDDIDRADLFFVIGANMAPWP
MAB_2438|M.abscessus_ATCC_1997 HIESNSRLCMASAGTGYAQSLGADGPPGSYSDIEHSDLFFVIGANMADCH
MMAR_3639|M.marinum_M QIESNSRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCH
MUL_1474|M.ulcerans_Agy99 QIESNSRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCH
MAV_2075|M.avium_104 QIESNSRLCMASAGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCH
Mb2924c|M.bovis_AF2122/97 NLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQNPGTNH
Rv2900c|M.tuberculosis_H37Rv NLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQNPGTNH
MSMEG_2837|M.smegmatis_MC2_155 HVDGNTRLCTATAAEALKESFGCDGQPGSYTDVDHADVIALYGHNVAETQ
:: :.:* :. . *:* . . : *.: :::: : * * .
Mflv_3016|M.gilvum_PYR-GCK PILYLRMADRLKAG--ARLIVVDPRRTA-----------------TADKA
Mvan_3491|M.vanbaalenii_PYR-1 PILYLRMADRLKAG--AKLIVVDPRRTA-----------------TADKA
TH_4553|M.thermoresistible__bu -----RSATSTRS--------VAPR-------------------------
MAB_2438|M.abscessus_ATCC_1997 PILFLRMADRLSSG--ARLIVVDPRRTA-----------------TADRA
MMAR_3639|M.marinum_M PILFLRMMERVKSG--AKLIVVDPRRTA-----------------TADKA
MUL_1474|M.ulcerans_Agy99 PILFLRMMERVKSG--AKLIVVDPRRTA-----------------TADKA
MAV_2075|M.avium_104 PILFLRMMDRVKAG--AKLIVVDPRRTA-----------------TAEKA
Mb2924c|M.bovis_AF2122/97 PRMLSVLGKAKANG--AKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIA
Rv2900c|M.tuberculosis_H37Rv PRMLSVLGKAKANG--AKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIA
MSMEG_2837|M.smegmatis_MC2_155 TVLWMRMLDRLAGPNPPAIVCIDPRPTP-----------------VARHA
: *
Mflv_3016|M.gilvum_PYR-GCK DLYLPIRPGTDLALLNGILRVLVQDGA------IDEAFIAEHTEGWEAMP
Mvan_3491|M.vanbaalenii_PYR-1 DLYLPIRPGTDLALLNGILHLLVENGA------VDQEFIAEHTQGWESMP
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 DLFLQITPGTDLALLNGLLHLLVENGA------VDAEFIAQHTEGWDGMP
MMAR_3639|M.marinum_M DLFLQIAPGTDLALLNGLLHLIVENEQ------TDPQFISEFTEGWEVMP
MUL_1474|M.ulcerans_Agy99 DLFLQIAPGTDLALLNGLLHLIVENEQ------TDPQFISEFTEGWEVMP
MAV_2075|M.avium_104 DLFLQIAPGTDLALLNGLLHLIVENGH------TDGEFIAEFTEGWEVMP
Mb2924c|M.bovis_AF2122/97 DEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYR
Rv2900c|M.tuberculosis_H37Rv DEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYR
MSMEG_2837|M.smegmatis_MC2_155 TVHLAPLPGTNVALMNGLLHEILDHDW------MDHDYIEAHTVGFHELR
Mflv_3016|M.gilvum_PYR-GCK AFLADYPPSRVAEITGLAEADIRSAAAMIAEAGDWISCWTMGLNQSTHGT
Mvan_3491|M.vanbaalenii_PYR-1 EFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWLSCWTMGLNQSTHGT
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 EFLAGYAPAVVAAITGLAEEDIRTAARWIGEAREWMTLWTMGLNQSTHGT
MMAR_3639|M.marinum_M SFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGT
MUL_1474|M.ulcerans_Agy99 SFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGT
MAV_2075|M.avium_104 SFLEQYTPDRVSEITGIPEQDIRAAAQLIGEADNFMSCWTMGLNQSTHGT
Mb2924c|M.bovis_AF2122/97 RRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAV
Rv2900c|M.tuberculosis_H37Rv RRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAV
MSMEG_2837|M.smegmatis_MC2_155 KRVAEFPPERVADICGVDPDDVRRAGELIGTAERLLSTVLQGFYQSHQAT
Mflv_3016|M.gilvum_PYR-GCK WNTNAICNLHLATGAICRPGAGPMSLTGQPNAMGGREMGYMGPGLPGQRA
Mvan_3491|M.vanbaalenii_PYR-1 WNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGREMGYMGPGLPGQRS
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 WNTNAICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
MMAR_3639|M.marinum_M WNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
MUL_1474|M.ulcerans_Agy99 WNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
MAV_2075|M.avium_104 WNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRS
Mb2924c|M.bovis_AF2122/97 ATIGEVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMG-----------
Rv2900c|M.tuberculosis_H37Rv ATIGEVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMG-----------
MSMEG_2837|M.smegmatis_MC2_155 AAAVQVNNIHLVRGMLGRPGCGLLQMNGQPTAENTRECGADG-DLAGFRN
Mflv_3016|M.gilvum_PYR-GCK VLSAEDRSFVETQWDLEPGTVRTEVG-PGTVEMFRRIAGGDIKAVWIICT
Mvan_3491|M.vanbaalenii_PYR-1 VASAADRAFVEEQWDLEPGTIRADIG-PGTVEMFRQMGSGDIKAAWIICT
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 VKSPADRDFVEKRWQLPPGSIRAEFG-TGTVDMFAQMAAGNIKACWIICT
MMAR_3639|M.marinum_M VLSAPDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEIKACWIICS
MUL_1474|M.ulcerans_Agy99 VLSAPDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEIKACWIICS
MAV_2075|M.avium_104 VASAADREFVEDVWGVPRGRLRTEVG-TGTIDMFSRMADGQIKACWIICT
Mb2924c|M.bovis_AF2122/97 IWEKMPEQFLAALDREFGITSPRAHG-FDTVAAIRAMRDGRVSVFMGMGG
Rv2900c|M.tuberculosis_H37Rv IWEKMPEQFLAALDREFGITSPRAHG-FDTVAAIRAMRDGRVSVFMGMGG
MSMEG_2837|M.smegmatis_MC2_155 WANDSHIEELATLWNLDVTAIPHYAPPTHAMQMFRYAEEGSLRMLWVSAT
Mflv_3016|M.gilvum_PYR-GCK NPVASVANRDTVITGLQSAELVITQDAYVDTATNRYADIMLPATLWAEAD
Mvan_3491|M.vanbaalenii_PYR-1 NPVASVANRDAVVAGLSTAELVITQDVYADTATNRYADIVLPATLWAETD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 NPVASVANRKNVVDGLRRAELVIAQDAFLATATNEYADILLPAALWAESD
MMAR_3639|M.marinum_M NPVATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESD
MUL_1474|M.ulcerans_Agy99 NPVATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESD
MAV_2075|M.avium_104 NPVASVANRKTVLAGLERAELVIAQDAYLGTETSEYADVLLPAALWAETE
Mb2924c|M.bovis_AF2122/97 NFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTD
Rv2900c|M.tuberculosis_H37Rv NFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTD
MSMEG_2837|M.smegmatis_MC2_155 NPAVSLPELGRIRRILSQDRLFLVVQDLFLTETAQLADVVLPAAAWAEKT
Mflv_3016|M.gilvum_PYR-GCK AVMVNSGRTLTLLAQSVPAAGDARPDWELICGVARHLGFGDA-----FDH
Mvan_3491|M.vanbaalenii_PYR-1 AVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHLGFGDA-----FDY
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 GVSINSERTATLTNRAVEAPGDARPDWQLICDIATAMGFGDA-----FGY
MMAR_3639|M.marinum_M GVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMGFSES-----FSY
MUL_1474|M.ulcerans_Agy99 GVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMGFSES-----FSY
MAV_2075|M.avium_104 GVMVNSERNITLSQPAVAAPGGAMPDWQIIARIACEMGFSEA-----FSY
Mb2924c|M.bovis_AF2122/97 RDTRNGRKQLVSVEDSMSMVHLSR----------GSLHPPSD-----QVR
Rv2900c|M.tuberculosis_H37Rv RDTRNGRKQLVSVEDSMSMVHLSR----------GSLHPPSD-----QVR
MSMEG_2837|M.smegmatis_MC2_155 GTFTNADRTVHISDKAVDPPGQARSDFDIFLDYARRMDFRDRDGRPLPAW
Mflv_3016|M.gilvum_PYR-GCK KSSEEIFDEIRRFHNPRTGYDLRGVTYERLR-ATPVQWPCPSEDAPDRNP
Mvan_3491|M.vanbaalenii_PYR-1 KSSEQIFDEIRRFHNPGTGYDLRGITYERLR-DTPVQWPCASAEQSDRNP
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 SSSEEIFEEIRAFWNPRTGYDMRGMSYARLR-QGPVQWPCPPESEVDRNP
MMAR_3639|M.marinum_M SSAAEVFEEIKRFSNPATGYDLRGISHDRLR-ETPLQWPCPPDGASNRSP
MUL_1474|M.ulcerans_Agy99 SSAAEVFEEIKRFSNPATGYDLRGISHDRLR-ETPLQWPCPPDGASNRSP
MAV_2075|M.avium_104 SCAEEVFEEIKRFWNPTTGYDLRGVSYERLR-RQPLQWPCPPQSTADRNP
Mb2924c|M.bovis_AF2122/97 SEVQIICQLARALFGPGHPVPWERFADDYDT-IRDAIAAVVPGCDDYNHK
Rv2900c|M.tuberculosis_H37Rv SEVQIICQLARALFGPGHPVPWERFADDYDT-IRDAIAAVVPGCDDYNHK
MSMEG_2837|M.smegmatis_MC2_155 NTPDEAFEAWKRCS-AGRPCDYTGLSYEKLRGSGGIQWPCNAEHPDGVER
Mflv_3016|M.gilvum_PYR-GCK IRYLNDGVSQDLHIDDDGH---------IPRLAFATPSRRAVFHPRPHLD
Mvan_3491|M.vanbaalenii_PYR-1 IRYLNDGVSQDQYVGPDGH---------RPRLAFPTPSRRAVFHPRPHMD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 IRYLNDGISQHPHVDENGV---------VPRLAFPTPSRRAVFHARAHRD
MMAR_3639|M.marinum_M IRYLNDGVSQLQFVRADGT---------VPRLAFPTATGRAVFFARPHLV
MUL_1474|M.ulcerans_Agy99 IRYLNDGVSQLQFVRADGT---------VPRLAFPTATGRAVFFARPHLV
MAV_2075|M.avium_104 IRYLNDGVSQTQLVREDGT---------VPRLAFPTPSGRAVFFARPHLQ
Mb2924c|M.bovis_AF2122/97 VRVPDG------FQLPHPP---------RDAREFRTSTGKANFAVNPLQW
Rv2900c|M.tuberculosis_H37Rv VRVPDG------FQLPHPP---------RDAREFRTSTGKANFAVNPLQW
MSMEG_2837|M.smegmatis_MC2_155 LYAGGEFFAAPDYCEAYGKDLITGAPLEPTEYRAMNPFGKAIIKAAEYVP
Mflv_3016|M.gilvum_PYR-GCK AAELPDDDYPFILNTGRLQHQWHTMTKTGRVAKLTKLNPAPFVEIHPSDA
Mvan_3491|M.vanbaalenii_PYR-1 AAELPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDA
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 PAELPGEGYPVVLNTGRLQHHWHTLTKTGRIKTLDRLHPSPFVEIHPHDA
MMAR_3639|M.marinum_M PDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDA
MUL_1474|M.ulcerans_Agy99 PDEMPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDA
MAV_2075|M.avium_104 PEEMPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDA
Mb2924c|M.bovis_AF2122/97 VPVPPGR---LVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADI
Rv2900c|M.tuberculosis_H37Rv VPVPPGR---LVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADI
MSMEG_2837|M.smegmatis_MC2_155 PHERPSAEYPCVLITGRTVYHFHTRTKTGRTPQLQAAAPEVWVELARADA
Mflv_3016|M.gilvum_PYR-GCK AALGITDGQDLELRTRRGRAVLPAVLTERVRPGNTWAPFH---WNDEHGE
Mvan_3491|M.vanbaalenii_PYR-1 AALGISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFH---WNDEHGD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 TTLGISDGDIVEIASRRGTAELPALVSDRVKRGSCFAPFH---WNDAHGP
MMAR_3639|M.marinum_M ADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFH---WNDAFGE
MUL_1474|M.ulcerans_Agy99 ADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFH---WNDAFGE
MAV_2075|M.avium_104 ARLGIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFH---WNDAFGE
Mb2924c|M.bovis_AF2122/97 ETFGLTAGDRVDLVSEWTDGQG----GLQERRAKDFLVVA---YSTPVGN
Rv2900c|M.tuberculosis_H37Rv ETFGLTAGDRVDLVSEWTDGQG----GLQERRAKDFLVVA---YSTPVGN
MSMEG_2837|M.smegmatis_MC2_155 LRAGIVEGDLVEIRTVRG-CVTAAARLTDLRRGVVFLPFHYGYWDTGDDG
Mflv_3016|M.gilvum_PYR-GCK NLTINALTN-----DAVDPDSLQPEFKVCAVRLTPVPAADG---------
Mvan_3491|M.vanbaalenii_PYR-1 HLTVNALTN-----DAVDPDSLQPEFKVCAVRLAPVPAAG----------
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 GLTINAVTN-----DAVDPDSLQPEFKVSAVALRPT--------------
MMAR_3639|M.marinum_M YLSINAVTN-----DAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPAD
MUL_1474|M.ulcerans_Agy99 YLSINAVTN-----DAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPAD
MAV_2075|M.avium_104 YLSINAVTN-----DAVDPISNQPEFKACAVTLTKVAVSHPDSAIG-TGP
Mb2924c|M.bovis_AF2122/97 AAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA-------------
Rv2900c|M.tuberculosis_H37Rv AAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA-------------
MSMEG_2837|M.smegmatis_MC2_155 GKDGHHRAANELTLTDWDPVSKQPIFKTAAASVRRIG-------------
Mflv_3016|M.gilvum_PYR-GCK -----------------------------------APDLTDDEKLYIAGF
Mvan_3491|M.vanbaalenii_PYR-1 -----------------------------------APEFTETEKLYLAGF
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3639|M.marinum_M TCADATAPKLLADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGL
MUL_1474|M.ulcerans_Agy99 ACADATAPKLLADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGL
MAV_2075|M.avium_104 SAGHDTPESAPTEVREISVSQVDALGELLGVATSFKPEFNELGRSYLAGM
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK LAGVDEGR----PGVPVLPAGAPVGARARLWVDGLLAGRYSRLETAAPSA
Mvan_3491|M.vanbaalenii_PYR-1 FAGIEEGL----PGVPVLPASAPVGPRARLWVDGLLAGRYSRSDTVAETP
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 -------------------------------------GRTKADSMPEKQK
MMAR_3639|M.marinum_M IAGLRSETGRRMAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALP
MUL_1474|M.ulcerans_Agy99 IAGLRSETGRRMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALP
MAV_2075|M.avium_104 LTGLRSDVGRRAGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAA
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK S----------------------PRGGPLVLWASQTGTAEEFAGSLGERL
Mvan_3491|M.vanbaalenii_PYR-1 A----------------------TEG-PLVLWASQTGNAEEFAGRLGERL
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 E----------------------ALGDVAILWTSQTGNAETAAVSVHRLL
MMAR_3639|M.marinum_M FPQTPGAAAQSDNAAEA----AVEQPPIVVLWASQTGTAEELAASVAAQL
MUL_1474|M.ulcerans_Agy99 FPQTPGAAAQSDNAAEA----AVEQPPIVVLWASQTGTAEELAASVAAQL
MAV_2075|M.avium_104 LPEPPQPAAQQPPAAPAGATPAPERAPVVVLWASQTGNAEELAADVAAQL
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------AGMAATPEPVAHAVADEH
Mflv_3016|M.gilvum_PYR-GCK AGA----RLRAMDDTDLSELSDAGEVVIVTSTFGDGGPPDNGTAFWERLE
Mvan_3491|M.vanbaalenii_PYR-1 NGA----RLRAMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGFWERLE
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 HTAGISATITAMDECDPADLVGVNTAVVIASSFGEGGPPDNGARFWAALS
MMAR_3639|M.marinum_M SAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELC
MUL_1474|M.ulcerans_Agy99 SAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELC
MAV_2075|M.avium_104 AAAELPVALHSMDDFPAAELAATRELLLITSTTGDGDAPDNGSGLWRALT
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 L-------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK SADAPALDGVRYTVLGIGDRSYDNFCGHAKSLDTRLADLGATRMLDRADC
Mvan_3491|M.vanbaalenii_PYR-1 SPHAPSLDGVRYTVLGIGDRSYDNFCGHARSLDARLADLGATRMLDRVEC
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 G-DTKPLNHMRYAVLGFGDRAYADFCGHAKALDARLHELGASPLLGRVDG
MMAR_3639|M.marinum_M AATAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDC
MUL_1474|M.ulcerans_Agy99 APTAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDC
MAV_2075|M.avium_104 GDAAPRLGNTRYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDC
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK EAYDEQPMAAWADSVVGLMST----------------PVTPAPTQPAVPA
Mvan_3491|M.vanbaalenii_PYR-1 EAYDAQPLARWADSVVELVAA----------------PGTPP---AAPAQ
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 EATDRTLVASWTADLLDAIGDGATAI---------VETVRKLRSEGLRVA
MMAR_3639|M.marinum_M EPDYEESAARWLQEVLDGLRRTAPPV---------ITAAPVRAASIANR-
MUL_1474|M.ulcerans_Agy99 EPDYEESAARWLQEVLDGLRRTAPPV---------ITAEPVRAASIASR-
MAV_2075|M.avium_104 EPDYEQAAAKWVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTP
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK APAPFTRGNPAQAPLCRNVRLTPDGAGKDVRQFGFDISGQDLAYSVGDSL
Mvan_3491|M.vanbaalenii_PYR-1 EPTLFTRAEPVAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGDSL
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 APERFTRDAPILAALSHNELLSAPNSGKEVRRIEFDLTGHDVSYSAGDAL
MMAR_3639|M.marinum_M -PQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDAL
MUL_1474|M.ulcerans_Agy99 -PQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDAL
MAV_2075|M.avium_104 APHTYSKKHPLITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYEAGDAL
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK GVWVVNSDAVVESWLSATGFHGAEAVIVDGR-QISLREALTRHYDVCKVT
Mvan_3491|M.vanbaalenii_PYR-1 GVCVVNSDFVVENWLAATDLRGDEAVVVDGV-QQALRDALTAHYDVCKVT
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 GIYPTNREEDVQRWLTTTGFDAQLPVTIDGG-ELPLATALANHYDICRVT
MMAR_3639|M.marinum_M GVWPRNAHQLVDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAHLS
MUL_1474|M.ulcerans_Agy99 GVWPRNAHQLVDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAHLS
MAV_2075|M.avium_104 GVWPRNSDELVDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIEIAHIS
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK SNLVTFVAEHCPDA----ATAKRLRN-DRGALDTWLVDRNGLDLVREFGI
Mvan_3491|M.vanbaalenii_PYR-1 SNLVKFVAEHCRDA----ATAKRLRN-DRGELDRWLVNRNGLDLVREFSV
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 EDLLRFIAERRRDK----HSAKLLQGRDTQAREVWLRGRNALDVIREFPI
MMAR_3639|M.marinum_M PDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPV
MUL_1474|M.ulcerans_Agy99 PDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPV
MAV_2075|M.avium_104 RDLVRFVQERTGDA----KLAELLKPENKRALADWTWGRQSIDLLAQLPV
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK RADPALWQEVLVRLTPRQYSISSSPLVSPHEVQLTVSVVRYRGADGTPRG
Mvan_3491|M.vanbaalenii_PYR-1 RADPQLWQEVLVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGPRG
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 RAAIEEWQQVLIRLTPRQYSISSSPLVSPQAISLTVSIVRYQGPDGSPRG
MMAR_3639|M.marinum_M RASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRR
MUL_1474|M.ulcerans_Agy99 RASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRR
MAV_2075|M.avium_104 SASAHEWLRVLKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQGVPRR
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK GVASTYLADLPDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGIAPFRG
Mvan_3491|M.vanbaalenii_PYR-1 GVASTYLADLPDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPFRG
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 GVGSTFLADRAQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGTGIAPFRG
MMAR_3639|M.marinum_M GVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRG
MUL_1474|M.ulcerans_Agy99 GVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRG
MAV_2075|M.avium_104 GVCSTYLAARSPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGIAPFRG
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK FLQERRALGHRGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRLDLAFS
Mvan_3491|M.vanbaalenii_PYR-1 FLQERRALGHRGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLAFS
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 FLQERRALGHTGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRLDLAFS
MMAR_3639|M.marinum_M FLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFS
MUL_1474|M.ulcerans_Agy99 FLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFS
MAV_2075|M.avium_104 FLQERRALGHRGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFS
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK RDQRQRIYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAKDVDDALTEI
Mvan_3491|M.vanbaalenii_PYR-1 RDQARRVYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALTEI
TH_4553|M.thermoresistible__bu --------------------------------------------------
MAB_2438|M.abscessus_ATCC_1997 RDQAKRIYVQHRMMEQGAQLWRWLNEGAHLYVCGDASRMAKDVDGALLTI
MMAR_3639|M.marinum_M RDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQI
MUL_1474|M.ulcerans_Agy99 RDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQI
MAV_2075|M.avium_104 RDQQHKVYVQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDI
Mb2924c|M.bovis_AF2122/97 --------------------------------------------------
Rv2900c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK LRTHARMSSDAAREYKREMVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1 IRTHGGMSADAARDYKREMVAEKRYVRDVY
TH_4553|M.thermoresistible__bu ------------------------------
MAB_2438|M.abscessus_ATCC_1997 AQKHGKLSGEQALEFRKELVAEKRYVRDVY
MMAR_3639|M.marinum_M VAEHGGLDPESATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99 VAEHGGLDPESATAFVHALSADKRYHRDVY
MAV_2075|M.avium_104 AAEFGNLDPDAAKAYVQSLSADKRYHRDVY
Mb2924c|M.bovis_AF2122/97 ------------------------------
Rv2900c|M.tuberculosis_H37Rv ------------------------------
MSMEG_2837|M.smegmatis_MC2_155 ------------------------------