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M. tuberculosis H37Rv Rv1161 (narG)

annotation: PROBABLE RESPIRATORY NITRATE REDUCTASE (ALPHA CHAIN) NARG
coordinates: 1287328 - 1291026
length: 1232

VTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRWSHDKVVRSTHGVNCTGSCSW
KIYVKDGIITWETQQTDYPSVGPDRPEYEPRGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLG
DPVLAWADIQADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAGFSPIPAMSMVSH
AAGSRFVELIGGVMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDASYLVMWGSNVPITRTPDAHWMAE
ARYRGAKVVVVSPDYADNTKFADEWVRCAAGTDTALAMAMGHVILSECYVRNQVPFFVDYVRRYTDLPFL
IKLEKRGDLLVPGKFLTAADIGEESENAAFKPALLDELTNTVVVPQGSLGFRFGEDGVGKWNLDLGSVVP
ALSVEMDKAVNGDRSAELVTLPSFDTIDGHGETVSRGVPVRRAGKHLVCTVFDLMLAHYGVARAGLPGEW
PTGYHDRTQQNTPAWQESITGVPAAQAIRFAKEFARNATESGGRSMIIMGGGICHWFHSDVMYRSVLALL
MLTGSMGRNGGGWAHYVGQEKVRPLTGWQTMAMATDWSRPPRQVPGASYWYAHTDQWRYDGYGADKLASP
VGRGRFAGKHTMDLLTSATAMGWSPFYPQFDRSSLDVADEARAAGRDVGDYVAEQLAQHKLKLSITDPDN
PVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNVQSDPPTDGVHPRDVVWDSDIPEGKLDLIMSIDF
RMTSTTLVSDVVLPAATWYEKSDLSSTDMHPYVHSFSPAIDPPWETRSDFDAFAAIARAFSALAKRHLGT
RTDVVLTALQHDTPDEMAYPDGTERDWLATGEVPVPGRTMSKLTVVERDYTAIYDKWLTLGPLIDQFGMT
TKGYTVHPFREVSELAANFGVMNSGVAVGRPAITTAKRMADVILALSGTCNGRLAVEGFLELEKRTGQRL
AHLAEGSEERRITYADTQARPVPVITSPEWSGSESGGRRYAPFTINIEHLKPFHTLTGRMHFYLAHDWVE
ELGEQLPVYRPPLDMARLFNQPELGPTDDGLGLTVRYLTPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSP
GDAAKINVRDNDWVEAVNANGIYVCRAIVSHRMPEGVVFVYHVQERTVDTPRTETNGKRGGNHNALTRVR
IKPSHLAGGYGQHAFAFNYLGPTGNQRDEVTVVRRRSQEVRY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1161narG-100% (1232)PROBABLE RESPIRATORY NITRATE REDUCTASE (ALPHA CHAIN) NARG
M. tuberculosis H37RvRv1736cnarXe-14485.05% (281) nitrate reductase NarX
M. tuberculosis H37RvRv1442bisC1e-0824.47% (331) biotin sulfoxide reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1193narG0.099.84% (1232) respiratory nitrate reductase subunit alpha NarG
M. gilvum PYR-GCKMflv_2156-0.079.68% (1235) nitrate reductase, alpha subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3041-1e-0627.32% (183) putative biotin sulfoxide reductase BisC
M. marinum MMMAR_2605-5e-0626.89% (212) anaerobic dehydrogenase
M. avium 104MAV_1303-0.087.34% (1232) nitrate reductase, alpha subunit
M. smegmatis MC2 155MSMEG_5140-0.079.92% (1230) nitrate reductase, alpha subunit
M. thermoresistible (build 8)TH_1885narX0.080.78% (1233) PROBABLE NITRATE REDUCTASE NARX
M. ulcerans Agy99MUL_3154-3e-0626.37% (201) dehydrogenase
M. vanbaalenii PYR-1Mvan_4546-0.080.24% (1235) nitrate reductase, alpha subunit

CLUSTAL 2.0.9 multiple sequence alignment


Rv1161|M.tuberculosis_H37Rv         MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW
Mb1193|M.bovis_AF2122/97            MTVTPHVGGPLEELLERSGRFFTPGEFSADLRTVTRRGGREGDVFYRDRW
MAV_1303|M.avium_104                MTATPHVGGVLEELLERSGRFFTPGEFSADLRTVTRQGGREADVFYRDRW
Mflv_2156|M.gilvum_PYR-GCK          MSTPPRTGGVVEDLLARSGRFFTPGEFSDDLRTVTRRGGRDGDIFYRDRW
Mvan_4546|M.vanbaalenii_PYR-1       MTSPPRTGGVVEELLQRSGRFFTPGDFSEDLRTVTRRGGRDGDVFYRDRW
TH_1885|M.thermoresistible__bu      VTSPPRVGGPIEDLLQRSGRFFTPGDVSDDGRIVHRRGGREGDVFYRDRW
MSMEG_5140|M.smegmatis_MC2_155      ----------MEELLQRSGRFFTPGTFSSDLRTVSRQGGREGDVFYRDRW
MMAR_2605|M.marinum_M               ------------------------------------------------MA
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
Mb1193|M.bovis_AF2122/97            SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
MAV_1303|M.avium_104                SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEP
Mflv_2156|M.gilvum_PYR-GCK          SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
Mvan_4546|M.vanbaalenii_PYR-1       SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
TH_1885|M.thermoresistible__bu      SHDKVVRSTHGVNCTGSCSWKVYVKDGIITWETQETDYPSVGPDRPEYEP
MSMEG_5140|M.smegmatis_MC2_155      SHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQETDYPSVGPDRPEYEP
MMAR_2605|M.marinum_M               TVDDGRHLHTCPLCEAMCGLEIRVADGPS-----GGRVVGIRGNRDDVWS
MUL_3154|M.ulcerans_Agy99           ----------------MCGLEIRVADGLS-----GGRVVSIRGNRDDVWS
MAB_3041|M.abscessus_ATCC_1997      ----MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDP
                                                     ..    .  *            .:   . :  .

Rv1161|M.tuberculosis_H37Rv         RG--CPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWAD
Mb1193|M.bovis_AF2122/97            RG--CPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKTRLGDPVLAWAD
MAV_1303|M.avium_104                RG--CPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWAD
Mflv_2156|M.gilvum_PYR-GCK          RG--CPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARIGDPVLAWAD
Mvan_4546|M.vanbaalenii_PYR-1       RG--CPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWAD
TH_1885|M.thermoresistible__bu      RG--CPRGAAFSWYTYSPTRVRYPYARGVLVEMYREAKARLTDPVLAWAD
MSMEG_5140|M.smegmatis_MC2_155      RG--CPRGAAFSWYTYSPTRVRYPYARGVLVEMYREARARLGDPVLAWAD
MMAR_2605|M.marinum_M               RGHICPKGASLGALHDDPDRIRHPMIK-----------------------
MUL_3154|M.ulcerans_Agy99           RGHICPKGASLGALHDDPDRIRHPMIR-----------------------
MAB_3041|M.abscessus_ATCC_1997      SP----LLQNIPGSIRHQARVTAPAVRSGWLREGPGPSDK----------
                                              :        *:  *  :                       

Rv1161|M.tuberculosis_H37Rv         IQADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAG
Mb1193|M.bovis_AF2122/97            IQADPERRRRYQQARGKGGLVRVSWAEASEMVAAAHVHTIKTYGPDRVAG
MAV_1303|M.avium_104                IQADPERRRRYQRARGKGGLVRITWAEATELIAAAHVHTIKTYGPDRVAG
Mflv_2156|M.gilvum_PYR-GCK          IQADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTVKTYGPDRVAG
Mvan_4546|M.vanbaalenii_PYR-1       IQADPQRRRRYQQARGKGGLVRVTWAEATEMIAAAHVHTIKTYGPDRVAG
TH_1885|M.thermoresistible__bu      IQADPQRRRRYQQARGKGGLVRISWAEATEMIAAAHVHTIKTHGPDRVAG
MSMEG_5140|M.smegmatis_MC2_155      IQADPERRRRYQSARGKGGLVRVSWAEATEMIAAAHVHTIKTYGPDRIAG
MMAR_2605|M.marinum_M               ---------------IDGQWHEVSWDAAFRRCTELLAPVIDTYGIGAVTA
MUL_3154|M.ulcerans_Agy99           ---------------IDGQWHEVSWDAAFRRCTELLAPVIDTYGIGAVTA
MAB_3041|M.abscessus_ATCC_1997      --------------RGADEYVEVSWDELTELLADELRRVVDTHGNEAIYG
                                                     .   .::*    .  :     .:.*:*   : .

Rv1161|M.tuberculosis_H37Rv         FSP---IPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLP---VASPQVF
Mb1193|M.bovis_AF2122/97            FSP---IPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLP---VASPQVF
MAV_1303|M.avium_104                FSP---IPAMSMVSYTAGSRFFELIGAPMTSFYDWYADLP---VASPQVF
Mflv_2156|M.gilvum_PYR-GCK          FSP---IPAMSMVSHAAGARFVSLIGGAMTSFYDWYADLP---VASPQVF
Mvan_4546|M.vanbaalenii_PYR-1       FSP---IPAMSMVSHAAGSRFVELVGGAMTSFYDWYADLP---VASPQVF
TH_1885|M.thermoresistible__bu      FSP---IPAMSMVSFAAGSRFIELLGGVMTSFYDWYADLP---VASPQVF
MSMEG_5140|M.smegmatis_MC2_155      FSP---IPAMSMVSHAAGSRFVELIGGVMTSFYDWYADLP---VASPQVF
MMAR_2605|M.marinum_M               YTG---NPLAHSFSLARYAGVLLGMSGMPVTYSPGTVDQWPKNLSSHLMY
MUL_3154|M.ulcerans_Agy99           YTG---NPLAHSFSLARYAGVLLGMSGMPVTYSPGTVDQWPKNLSSHLMY
MAB_3041|M.abscessus_ATCC_1997      GSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATG--VIMPHVI
                                     :     .     : :    ..  :..   :      .     :    : 

Rv1161|M.tuberculosis_H37Rv         GDQTDVPESGDWWDAS-----YLVMWG----SNVPITR-----TPDAHWM
Mb1193|M.bovis_AF2122/97            GDQTDVPESGDWWDAS-----YLVMWG----SNVPITR-----TPDAHWM
MAV_1303|M.avium_104                GDQTDVPESGDWWDAA-----YLMMWG----SNVPITR-----TPDAHWM
Mflv_2156|M.gilvum_PYR-GCK          GDQTDVPESGDWWDAT-----YLMMWG----SNVPVTR-----TPDAHWM
Mvan_4546|M.vanbaalenii_PYR-1       GDQTDVPESGDWWDAS-----YLMMWG----SNVPVTR-----TPDAHWM
TH_1885|M.thermoresistible__bu      GDQTDVPESGDWWDAA-----YLMMWG----SNVPVTR-----TPDAHWM
MSMEG_5140|M.smegmatis_MC2_155      GDQTDVPESGDWWDAA-----YLMMWG----SNVPVTR-----TPDAHWM
MMAR_2605|M.marinum_M               GGWWTFPVP-DIERTD-----LLVIMG----ANPAASQGSLLAAPDVMGL
MUL_3154|M.ulcerans_Agy99           GGWWTFPEP-DIERTG-----LLVIMD----ANPAASQGSLLAAPDVMGL
MAB_3041|M.abscessus_ATCC_1997      GTHDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDAL
                                    *    .        .       *:  .     *   .:      *    :

Rv1161|M.tuberculosis_H37Rv         AEARYRGAKVVVVSPDYADNTKFADEWVRCAAGTDTALAMAMGHVILSEC
Mb1193|M.bovis_AF2122/97            AEARYRGAKVVVVSPDYADNTKFADEWVRCAAGTDTALAMAMGHVILSEC
MAV_1303|M.avium_104                AEARYRGTKVVTVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILSEC
Mflv_2156|M.gilvum_PYR-GCK          AEVRYRGTKVVSVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILTEN
Mvan_4546|M.vanbaalenii_PYR-1       AEVRYRGTKVVSVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILTEN
TH_1885|M.thermoresistible__bu      AEVRYRGTKVVAVSPDYADNTKFADEWMPCAAGTDGAMAMAMGHVILSEF
MSMEG_5140|M.smegmatis_MC2_155      AEVRYRGTKVVSVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILSEC
MMAR_2605|M.marinum_M               IDAIRQRGKVIVIDPVRTVTAARADEWLPIVPGTDAALLLAVAHTLFDED
MUL_3154|M.ulcerans_Agy99           IDAIRQRGKVIVIDPVRTVTAARADEWLPIVPGTDAALLLAVAHTLFDED
MAB_3041|M.abscessus_ATCC_1997      NRFRDRGGRIVSFSPLHDDIDG-ECEWHAPIPGTDVAVMLALAHVLAVEK
                                         :  ::: ..*          **    .*** *: :*:.*.:  * 

Rv1161|M.tuberculosis_H37Rv         YVRNQVPFFVDYVRRYTDLPFLIKLEKRGDLLVPGKFLTAADIG---EES
Mb1193|M.bovis_AF2122/97            YVRNQVPFFVDYVRRYTDLPFLIKLEKRGDLLVPGKFLTAADIG---EES
MAV_1303|M.avium_104                YVQKQVPFFTDYARRYTDLPFLIKLEERGDMLVPGKNLTAADLG---EAV
Mflv_2156|M.gilvum_PYR-GCK          YVRQRVPFFDEYVRTYTDLPFLVKLEERGGVTVPGKMLTAADLGPAYGG-
Mvan_4546|M.vanbaalenii_PYR-1       FVRRRVPFFVDYVRTYTDLPFLVKLEERDGVLVPGKMLTAADLGPGYDGQ
TH_1885|M.thermoresistible__bu      FVRKQVPFFTDYVRRYTDLPFLVKLEERDGALVPGKMLTVADLGEVFGQH
MSMEG_5140|M.smegmatis_MC2_155      FVQNEVPYFTDFARRFTDLPFLAKLEERDGALVPGKNLTAADLTPDVAAQ
MMAR_2605|M.marinum_M               LVN------------------------------PGPHVDGVDTMRR----
MUL_3154|M.ulcerans_Agy99           LVN------------------------------PGQHVDGVDTMRR----
MAB_3041|M.abscessus_ATCC_1997      LAD---------------------------LTFLSSYCTGYERFER----
                                     .                                .      :        

Rv1161|M.tuberculosis_H37Rv         ENAAFKPALLDELTNTVVVPQGSLGFRFGEDGVGKWNLDLGSVVPALSVE
Mb1193|M.bovis_AF2122/97            ENAAFKPALLDELTNTVVVPQGSLGFRFGEDGVGKWNLDLGSVVPALSVE
MAV_1303|M.avium_104                ENAALKPALLDETTNSVAVPHGSLGFRYGESGVGKWNLDLGDLVPALSVR
Mflv_2156|M.gilvum_PYR-GCK          ENAEFKPALLNLATDSVTVPPGSLGFRYGDEGVGRWNLDLGDVVPALTVA
Mvan_4546|M.vanbaalenii_PYR-1       ENAAFKPVLLDGATDSVVVPPGSLGFRYGDEGVGKWNLDLGDVVPALTVA
TH_1885|M.thermoresistible__bu      ENAAFKPMLLDEATDTVTVPHGSLGFRYGTDGAGKWNLDLGPVVPALTVR
MSMEG_5140|M.smegmatis_MC2_155      ENAAFKPALLDSASDSIAIPQGSLGFRFGESGLGNWNLDLENLAPALTVA
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         MDKAVNGDRSAELVTLPSFDTIDGHGETVSRGVPVRRAGKHLVCTVFDLM
Mb1193|M.bovis_AF2122/97            MDKAVNGDRSAELVTLPSFDTIDGHGETVSRGLPVRRAGKHLVCTVFDLM
MAV_1303|M.avium_104                AAPTEDGE--TALVHLPSFDTVDGEGTTVARGVPVRRVGKHLVCTVFDLM
Mflv_2156|M.gilvum_PYR-GCK          TGDVHDGG--SAAVTLSRFDTVDGHGATMLRGVPVRQVGAHRVCTVFDLM
Mvan_4546|M.vanbaalenii_PYR-1       PPDGQSGE--TTSISLTRFDTVDGRGATLQRGVPVRRVGEHRVCTVFDLM
TH_1885|M.thermoresistible__bu      TGD---GP--VTEVRLPCFDSVDGHGTTVTRGVPVRHVGDHRVCTVFDLM
MSMEG_5140|M.smegmatis_MC2_155      ADT---GE--TAEVTLPRFDTLDGHGDTMVRGVPVRRVGEHLVCTVFDLM
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         LAHYGVARAGLPGEWPTGYHDRTQQNTPAWQESITGVPAAQAIRFAKEFA
Mb1193|M.bovis_AF2122/97            LAHYGVARAGLPGEWPTGYHDRTQQNTPAWQESITGVPAAQAIRFAKEFA
MAV_1303|M.avium_104                LAQYGVARPGLPGEWPTGYDDATQQNTPAWQEAITGVSAAQATRVAREFA
Mflv_2156|M.gilvum_PYR-GCK          LAQYGVARPGLPGDWPTGYDDPRSPYTPAWQEPITGVSAGQAIRVAREFA
Mvan_4546|M.vanbaalenii_PYR-1       LAQYGVARPGLPGDWPAGYDDPDQPYTPAWQESITGVSASQAIRVAREFA
TH_1885|M.thermoresistible__bu      LAQYGVSRPGLPGDWPTGYDDATRPYTPAWQEPITGVSAAQVIRIATEFA
MSMEG_5140|M.smegmatis_MC2_155      LAQYGVARPGLPGDWPTGFDDATRPYTPAWQEPITGVAAAQAIRVAREFA
MMAR_2605|M.marinum_M               ----------VAADWPP-----------ARVSAVTGIEEERIRRLARELA
MUL_3154|M.ulcerans_Agy99           ----------VAGSS-----------------------RDKTARKVFSLG
MAB_3041|M.abscessus_ATCC_1997      ------YLLGVDDGVPK---------SPEWAAPISGLDAAELRTLARRMA
                                              :                             .    .  :.

Rv1161|M.tuberculosis_H37Rv         RNATESGGRSMIIMGGGICHWFHSDVMYRSVLALLMLTGSMGRNGGGWAH
Mb1193|M.bovis_AF2122/97            RNATESGGRSMIIMGGGICHWFHSDVMYRSVLALLMLTGSMGRNGGGWAH
MAV_1303|M.avium_104                RSAEESGGRSMIIMGGGICHWFHSDAIYRAVLALLMLTGSMGRNGGGWAH
Mflv_2156|M.gilvum_PYR-GCK          RNAEESGGRSMIIMGAGICQWFHGDTTYRAVLAMLLLTGSMGRNGGGWAH
Mvan_4546|M.vanbaalenii_PYR-1       RNAEESGGRSMIIMGAGICQWFHGDTTYRAVLAMLLLTGSMGRNGGGWAH
TH_1885|M.thermoresistible__bu      RNAEESGGRSMIIMGAGICQWFHGDATYRAVLALLLLTGSMGRNGGGWAH
MSMEG_5140|M.smegmatis_MC2_155      RNAEETRGRSMIIMGAGICQWFHGDATYRAVLALLLLTGSMGRNGGGWAH
MMAR_2605|M.marinum_M               G-----THKSVVYGRIGLCNQEFGSLASWLVDVINILTGHFDTPGG----
MUL_3154|M.ulcerans_Agy99           R-----RNR---------------------------------TPN-----
MAB_3041|M.abscessus_ATCC_1997      AG------RTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGH
                                            :                                   .     

Rv1161|M.tuberculosis_H37Rv         YVGQEKVRPLTGWQTMAMATDWSRPPRQVPGASYWYAHTDQWRYDGYGAD
Mb1193|M.bovis_AF2122/97            YVGQEKVRPLTGWQTMAMATDWSRPPRQVPGASYWYAHTDQWRYDGYGAD
MAV_1303|M.avium_104                YVGQEKVRPLTGFQTMAMATDWVRPPRQVPGASYWYAHTDQWRYDGYGAD
Mflv_2156|M.gilvum_PYR-GCK          YVGQEKCRPVTGWATMGSALDWSRPPRQMPGTSYWYAHTDQWRYDGYRAD
Mvan_4546|M.vanbaalenii_PYR-1       YVGQEKCRPVTGWATMAMATDWTRPPRQMPGTSYWYAHTGQWRYDGYRAD
TH_1885|M.thermoresistible__bu      YVGQEKCRPVTGWATMAMATDWSRPPRQMPGTSYWYVHTDQWNYDGYRAD
MSMEG_5140|M.smegmatis_MC2_155      YVGQEKCRPVTGWATMAMATDWSRPPRQMAGTSYWYAHTDQWRYDGYQAD
MMAR_2605|M.marinum_M               -------------AMFPRPAAWSITTQPLPGLEGGVAEFGRWHTRVRGAK
MUL_3154|M.ulcerans_Agy99           ---------------------WANTSS-----------------------
MAB_3041|M.abscessus_ATCC_1997      GYG------------SMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAISE
                                                             .                        

Rv1161|M.tuberculosis_H37Rv         KLASPVGRGRFAGKHTMDLLTSATAMGWSPFYPQFDRSSLDVADEARAAG
Mb1193|M.bovis_AF2122/97            KLASPVGRGRFAGKHTMDLLTSATAMGWSPFYPQFDRSSLDVADEARAAG
MAV_1303|M.avium_104                KLASPVGRGRFAGRHTMDLLASAVAMGWSPYYPQFDRSSLDVADEARAAG
Mflv_2156|M.gilvum_PYR-GCK          TLASPTARGRFTGKHTMDVVAAAAAMGWMPFYPQFDRNSLDIADEALAAG
Mvan_4546|M.vanbaalenii_PYR-1       ALASPTARGRFAGKHTMDVVAAAAAMGWMPFYPQFDRNSLDVADEARAAG
TH_1885|M.thermoresistible__bu      ALASPIGRGRFRGKHTMDVLASATAMGWSPFYPQFDRSSLDIADEARAAG
MSMEG_5140|M.smegmatis_MC2_155      ALSSPVGRGRFRGRHTMDVLASAAAMGWSPFFPQFDRSSLDVADEARAAD
MMAR_2605|M.marinum_M               EVLGQAPVSCLAEEIATPGDGQLRALITIAGNPVLSTPGGDKLDEALSS-
MUL_3154|M.ulcerans_Agy99           --------EAVAAHVAKPA-------------------------------
MAB_3041|M.abscessus_ATCC_1997      LLLRPGQTLAYNGQTLT--LPDIRCVYWAGGNPFHHHQNLPRLRRALSR-
                                                 .                                    

Rv1161|M.tuberculosis_H37Rv         RDVGDYVAEQLAQHKLKLSITDPDNPVNWPRVLTVWRANLIGSSGKGGEY
Mb1193|M.bovis_AF2122/97            RDVGDYVAEQLAQHKLKLSITDPDNPVNWPRVLTVWRANLIGSSGKGGEY
MAV_1303|M.avium_104                RDVADYVAEQLGRRNLKLAVTDPDNPVNWPRVLTVWRANLIGSSGKGGEY
Mflv_2156|M.gilvum_PYR-GCK          RDIPQYLCEKLASGELKMAVTDPDNPANWPRVLNVWRANLLGSSSKGNEY
Mvan_4546|M.vanbaalenii_PYR-1       QDIGKYVCEKLASGELKMAVTDPDNPANWPRVLNVWRANLLGSSSKGNEY
TH_1885|M.thermoresistible__bu      KEIGAYVCEQLASGGLKLAVTDPDDPRNWPRVLSVWRSNLLGSSSKGNEY
MSMEG_5140|M.smegmatis_MC2_155      QEIPAYVTAKLADGSLKLAVTDPDNPANWPRVLDVWRANLLGSSSKGNEY
MMAR_2605|M.marinum_M               --------------------------------------------------
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         FLRHLLGTDSNVQSDPPTDGVHPRDVVWDSDIPEGKLDLIMSIDFRMTST
Mb1193|M.bovis_AF2122/97            FLRHLLGTDSNVQSDPPTDGVHPRDVVWDSDIPEGKLDLIMSIDFRMTST
MAV_1303|M.avium_104                FLRHLLGTDSNASAVPPEDGVRPVDVTCGADIPEGKLDLMMSIDFRMTST
Mflv_2156|M.gilvum_PYR-GCK          FLRHLLGTDSNLQASPTPEALRPADVVWPDDIPEGKLDLLMSIDFRMTST
Mvan_4546|M.vanbaalenii_PYR-1       FLRHLLGADSNLQATPTEEALRPKDVTWPDDIPEGKLDLLMSVDFRMTST
TH_1885|M.thermoresistible__bu      FLRHLLGTDSNLRATRTPEALRPNDVRSPDEIPEGKLDLLMSIDFRMTST
MSMEG_5140|M.smegmatis_MC2_155      FLRHLLGTTSNLQAAPN--GVRPSSVTCTDDIPEGKLDLLMSIDFRMTST
MMAR_2605|M.marinum_M               ------------------------------------LEAMISVDLWLNET
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      ------------------------------------VDTVVVHDPVWTAM
                                                                                      

Rv1161|M.tuberculosis_H37Rv         TLVSDVVLPAATWYEKSDLSSTDMHPYVHSFSPAIDPPWETRSDFDAFAA
Mb1193|M.bovis_AF2122/97            TLVSDVVLPAATWYEKSDLSSTDMHPYVHSFSPAIDPPWETRSDFGAFAA
MAV_1303|M.avium_104                TLVSDVVLPAATWYEKADISSTDMHPYVHAFSAATDPPWETRSDFDAFGA
Mflv_2156|M.gilvum_PYR-GCK          TLLSDVVLPAATWYEKADLSSTDMHPYVHAFSPAIDPPWETRSDFDAFGA
Mvan_4546|M.vanbaalenii_PYR-1       TLLSDVVLPAATWYEKADLSSTDMHPYVHAFSPAIDPPWETRSDFEAFGA
TH_1885|M.thermoresistible__bu      TLLSDIVLPAATWYEKHDLSSTDMHPYVHAFSPAIDPPWETRSDYDAFGA
MSMEG_5140|M.smegmatis_MC2_155      TLLSDVVLPAATWYEKADLSSTDMHPYVHAFSPAVDPPWETRSDFEAFGA
MMAR_2605|M.marinum_M               TRHADVILPGLSPLEQPHHDDLVLQFAIRSFANYSAPVFDPGDRPHEWEI
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      AKHADIVVPSTTSLERDDFSGSRNDPLLVAMKAVAPPYANSRDDYTTFSA
                                                                                      

Rv1161|M.tuberculosis_H37Rv         IARAFSALAKRHLGTRTDVVLTALQHDTPDEMAYPDGTERDWLATGEVPV
Mb1193|M.bovis_AF2122/97            IARAFSALAKRHLGTRTDVVLTALQHDTPDEMAYPDGTERDWLATGEVPV
MAV_1303|M.avium_104                IARAFSTMAKEHLGTRTDVVLTALQHDTPDAMAYPDGAEHDWLRSGATPV
Mflv_2156|M.gilvum_PYR-GCK          VASAFSALARTHLGTRTDVVLGALQHDTPGAMAYPAGTQRDWRETGEVPV
Mvan_4546|M.vanbaalenii_PYR-1       IARTFSTLARSHLGTRTDVVLGALQHDTPGAMAYPAGTQRDWRETGETPV
TH_1885|M.thermoresistible__bu      IARAFSALARKHLGTRTDVVLGALQHDTPGAMAYAGGTERDWRVTGEVPV
MSMEG_5140|M.smegmatis_MC2_155      IARAFSTLAARHLGVRTDVVLGTLQHDTLGAMAYPSGTEHDWRVTGETPV
MMAR_2605|M.marinum_M               LIRLTGLCTGTPA---EDVDVAAIDDGFFDYLAFTKGFDGAAIRKRYEHD
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      LADRLGFGEQFSEGRTAAQWLRHIYTEWAGALNFSVPSFDEFWDRGYLEL
                                                                                      

Rv1161|M.tuberculosis_H37Rv         PGRTMSKLTVVERDYTAIYDKWLTLGPLIDQFGMTTKGYTVHPFREVSEL
Mb1193|M.bovis_AF2122/97            PGRTMSKLTVVERDYTAIYDKWLTLGPLIDQFGMTTKGYTVHPFREVSEL
MAV_1303|M.avium_104                PGRTMGKLTVVERDYAAVYDKWRTLGPLVDKFGLTTKGVTVHPFREVEEL
Mflv_2156|M.gilvum_PYR-GCK          PGATIGPIAVVERDYTAIADKWSTLGPLVEKLGLTTKGVTTHPDREADEL
Mvan_4546|M.vanbaalenii_PYR-1       PGKTIGPITVVERDYAAIADKWSTLGPLVERLGVTTKGVTTWPVQETAEL
TH_1885|M.thermoresistible__bu      PGKTIGPLAVVERDYTAIADKWAALGPLVEELGVTTKGVTTWPVQEVAEL
MSMEG_5140|M.smegmatis_MC2_155      PGRTMGPLAVVERDYGAIAQKWAALGPLVEGLGVTTKGLTTHPTREVAEL
MMAR_2605|M.marinum_M               G---------WAGGPERILDLTLRTGPFGDRYGQNPGGLTLDMLK-----
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      PTDAGLTLLSDFRENPAAHPLHTPSG-RIEIFSETIDGFGYSDCG-----
                                                                                      

Rv1161|M.tuberculosis_H37Rv         AANFGVMNSGVAVGRPAITTAKRMADVILALSGTCNGRLAVEGFLELEKR
Mb1193|M.bovis_AF2122/97            AANFGVMNSGVAVGRPAITTAKRMADVILALSGTCNGRLAVEGFLELEKR
MAV_1303|M.avium_104                AARFGVLKSGVAAGRPAITTAARMADVLLLLSGTTNGRLAVEGFHELEKR
Mflv_2156|M.gilvum_PYR-GCK          ARKFGVFDSGPAAGRPAITTAERMADVILALSGTSNGRLAVEGFRELQRR
Mvan_4546|M.vanbaalenii_PYR-1       AQKFGVLDSGPAAGQPAITTAERMADVILALSGTSNGRLAVEGFRELERR
TH_1885|M.thermoresistible__bu      AKAFGVMDSGPAAGRPAITTAARMAEVILALSGTSNGRLAVEGFRELEKR
MSMEG_5140|M.smegmatis_MC2_155      GAKFGVMDSGAAQGRPAITTGERMADVILALSGTSNGRLAVEGFAELERR
MMAR_2605|M.marinum_M               -------------ANPNGIDFGPMVSQLPDILGTPEKKIRLAPQYLLDDL
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      -------------------GHPQWYEPTEWLGGERAQR------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         TGQRLAHLAEGSEERRITYADTQARPVPVITSPEWSGSESGGRRYAPFTI
Mb1193|M.bovis_AF2122/97            TGQRLAHLAEGSEERRITYADTQARPVPVITSPEWSGSESGGRRYAPFTI
MAV_1303|M.avium_104                TGQRLVHLAEGSEDKRISYADTQARPVPVVTSPEWSGSETGGRRYAPFTI
Mflv_2156|M.gilvum_PYR-GCK          TGTPLAHLAEGSEERRITYADTQARPVPVITSPEWSGSETGGRRYAPFTV
Mvan_4546|M.vanbaalenii_PYR-1       TGRPLAHLAEGSEERRITYADTQARPVPVITSPEWSGSETGGRRYAPFTV
TH_1885|M.thermoresistible__bu      TGQRLAQLAEGSEERRITFADTQARPVPVITSPEWSGSETAGRRYAPFTV
MSMEG_5140|M.smegmatis_MC2_155      TGRKLVHLALGSEERRITYADAQARPVPVITSPEWSGSETGGRRYAPFTV
MMAR_2605|M.marinum_M               P---------------------------------------------RLAS
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      -----------------------------------------------FPL
                                                                                      

Rv1161|M.tuberculosis_H37Rv         NIEHLKPFHTLTGRMHFYLAHDWVEELGEQLPVYRPPLDMARLFNQPELG
Mb1193|M.bovis_AF2122/97            NIEHLKPFHTLTGRMHFYLAHDWVEELGEQLPVYRPPLDMARLFNQPELG
MAV_1303|M.avium_104                NIENLKPFHTLTGRMHFYLAHDWVEELGEHLPVFRPPLDMARLFGQPRLG
Mflv_2156|M.gilvum_PYR-GCK          NIEQLKPFHTLTGRMHFYLDHDWLEELGEQLPVYRPPLDLGRLFGEPAIG
Mvan_4546|M.vanbaalenii_PYR-1       NIEALKPFHTLTGRMHFYLDHDWLEELGEQLPVYRPPLDMARLFGEPAIG
TH_1885|M.thermoresistible__bu      NIEHLKPFHTLTGRMHFYLDHDWLEELGEQLPVYRPPLDMARLFGAQQIG
MSMEG_5140|M.smegmatis_MC2_155      NIEELKPFHTLTGRMHFYVDHDWLEELGEQLPVYRPPLDMARLFGESRLG
MMAR_2605|M.marinum_M               RMDRPAEQLVLVNRRHLRSNNSWLHNV-----------------------
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      HLIANQPRTRLHSQLDFGGTS-----------------------------
                                                                                      

Rv1161|M.tuberculosis_H37Rv         -----PTDDGLGLTVRYLTPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSP
Mb1193|M.bovis_AF2122/97            -----PTDDGLGLTVRYLTPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSP
MAV_1303|M.avium_104                -----ACEDGIGLTVRYLTPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSP
Mflv_2156|M.gilvum_PYR-GCK          ----APGATGVGLTVRYLTPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSP
Mvan_4546|M.vanbaalenii_PYR-1       ----ARG--ELGLTVRYLTPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSP
TH_1885|M.thermoresistible__bu      ----HSD--GVGLTVRYLTPHSKWSIHSEYQDNLLMLSLSRGGPTMWMSP
MSMEG_5140|M.smegmatis_MC2_155      AGPGADGAGGVGLTVRYLTPHSKWSIHSEYQDNLFMLSLSRGGPTMWMSP
MMAR_2605|M.marinum_M               ----------------------------------PALMKGKDRCTLLMHP
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      -----------------------------------QGSKVRGREPLRIHP
                                                                                      

Rv1161|M.tuberculosis_H37Rv         GDAAKINVRDNDWVEAVNANGIYVCRAIVSHRMPEGVVFVYHVQERTVDT
Mb1193|M.bovis_AF2122/97            GDAAKINVRDNDWVEAVNANGIYVCRAIVSHRMPEGVVFVYHVQERTVDT
MAV_1303|M.avium_104                GDAAKIQVRDNDWVEAVNANGIYVCRAIVSHRMPDGVVYVYHVQERTVDT
Mflv_2156|M.gilvum_PYR-GCK          ADAEKIEVRDNDWVEAVNRNGVLVCRAIVSHRMPEGVVYVYHAQERTIDV
Mvan_4546|M.vanbaalenii_PYR-1       ADAAKIQVRDNDWVEAVNRNGVLVCRAIVSHRMPEGVVYVYHAQERTIDV
TH_1885|M.thermoresistible__bu      ADAAKIGVADNDWVEAVNPNGVLVCRAIVSHRMPEGVVYVYHVQERTIDV
MSMEG_5140|M.smegmatis_MC2_155      GDADKIAVRDNDWVEAVNRNGVLVCRAIVSHRMPDGVVYVYHAQERTIDV
MMAR_2605|M.marinum_M               DDAARNGITDNDTVTVRSSAGEITVPVELTSAIKPGVVSMPHGWGHGKPG
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      QDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIE
                                                                                      

Rv1161|M.tuberculosis_H37Rv         PRTETNGKRGGNHNALTRVRIKPSHLAGGYGQHAFAFNYLGPTGNQRDEV
Mb1193|M.bovis_AF2122/97            PRTETNGKRGGNHNALTRVRIKPSHLAGGYGQHAFAFNYLGPTGNQRDEV
MAV_1303|M.avium_104                PRTETNDKRGGNHNALTRVRIKPSHLAGGYAQHAFAFNYLGPTGNQRDEV
Mflv_2156|M.gilvum_PYR-GCK          PLTETTGRRGGIHNSLTRLLVKPSHLAGGYAQTAFAFNYLGPTGNQRDEV
Mvan_4546|M.vanbaalenii_PYR-1       PLTETTGRRGGIHNSLTRLLVKPSHLAGGYAQTAFAFNYLGPTGNQRDEV
TH_1885|M.thermoresistible__bu      PIAETTGKRGGIHNSLTRLLIKPSHLAGGYAQNAFAFNYLGPTGNQRDEV
MSMEG_5140|M.smegmatis_MC2_155      PLTETTGTRGGIHNSLTRLLIKPSHLAGGYAQHSYAFNYLGPTGNQRDEV
MMAR_2605|M.marinum_M               TRLAVANSAPGVNTNVLSPPTLLDEPSGNGVLNGIPVTVS----------
MUL_3154|M.ulcerans_Agy99           --------------------------------------------------
MAB_3041|M.abscessus_ATCC_1997      PADPNSACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRA
                                                                                      

Rv1161|M.tuberculosis_H37Rv         TVVRRRSQEVRY-
Mb1193|M.bovis_AF2122/97            TVVRRRSQEVRY-
MAV_1303|M.avium_104                TIVRRRSQEVVY-
Mflv_2156|M.gilvum_PYR-GCK          TVVRRRSQEVVY-
Mvan_4546|M.vanbaalenii_PYR-1       TIVRRRSQEVVYQ
TH_1885|M.thermoresistible__bu      TVVRRRSQRVVF-
MSMEG_5140|M.smegmatis_MC2_155      TVVRRRSQEVTYR
MMAR_2605|M.marinum_M               -------------
MUL_3154|M.ulcerans_Agy99           -------------
MAB_3041|M.abscessus_ATCC_1997      HTPPRFVARD---