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SSMAVFPEAVSAAAANVANIGRALSAANAAATVPTTNLLAAGTDEISTAVASLFSGHGQAYQRLANQLMA FHDQFAQALTAGASAYTGAEATNASPLQTVEQNALGLINAPTQTLLGRPLIGDGAAGTATNPNGGAGGLL YGNGGAGFNNGATAGAAGGNGGNAGLIGNGGAGGNGGAGAAGGTGGNGGWLYGSGGAGGAGGNALVAGGT GGNGGAGGAAGLWGNGGAGGHGGSGLAGNSGVNPTPTHDTALNGADGDSNIYDAATNTVSATPGTDGTPG GAGVTGGNGGAGGSASQPVTSLTATASDGGNGAQGGQGGADGGTGGVAGVAASYNGVAIGGNGGNGGTGG TGTDGLAGSGGGSGGAGGRGGWLIGNGGAGGAGGAGGAGGNGAIGGDGGAAGFTGSNNDSAASTLYGAHG GTGGDGGAGGTGGHGGAGGAGGAGGVGGDGGWLIGDGGAGGQGGIGGMGGTGGAGGSGVAGAHGGNATSS IAAFGGDGGAGGDAGHGGMGGDGGNGGQGASGGRGGLLSGAQGVTGTAGDGGTGGAGGLHGAFGAGGDPG TGGGQGSDGKLGADGLGGAAFDGARGADGNPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1162 | - | - | 100% (593) | PE-PGRS family protein |
| M. marinum M | MMAR_1161 | - | 0.0 | 67.67% (597) | PE-PGRS family protein |
| M. marinum M | MMAR_4270 | - | e-166 | 51.22% (615) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3402 | PE_PGRS51 | 0.0 | 60.73% (634) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-106 | 45.97% (533) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3367 | PE_PGRS51 | 0.0 | 64.17% (600) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 38.46% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-50 | 30.10% (598) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 3e-19 | 36.36% (187) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-94 | 42.05% (585) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-42 | 40.94% (298) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3507 | - | 1e-153 | 52.85% (613) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-103 | 44.16% (539) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3402|M.bovis_AF2122/97 ------------------------------------MSFVVAVP------
Rv3367|M.tuberculosis_H37Rv ------------------------------------MSFVVAVP------
MMAR_1162|M.marinum_M ------------------------------------MSSMAVFP------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MUL_3507|M.ulcerans_Agy99 ------------------------------------MSFVSVTQ------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 ------------------------------------MNIVLGVSMAP---
Mb3402|M.bovis_AF2122/97 ----------------------------------------EALAAAASDV
Rv3367|M.tuberculosis_H37Rv ----------------------------------------EALAAAASDV
MMAR_1162|M.marinum_M ----------------------------------------EAVSAAAANV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MUL_3507|M.ulcerans_Agy99 ----------------------------------------EALAAAASDV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------VEAASYVADPEAALANAGLSA
MAV_4827|M.avium_104 ----------------------------------------SSIQMVVLEG
Mb3402|M.bovis_AF2122/97 AN---------------------------------------IGSALSAAN
Rv3367|M.tuberculosis_H37Rv AN---------------------------------------IGSALSAAN
MMAR_1162|M.marinum_M AN---------------------------------------IGRALSAAN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MUL_3507|M.ulcerans_Agy99 G---------------------------------------VIGSSLQAAN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VSAAQVG--------------------------------AVMPVVAESVA
MAV_4827|M.avium_104 EY--------------------------------------ADGATVEEDA
Mb3402|M.bovis_AF2122/97 AAAAAGTTGLLAAG-ADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQ
Rv3367|M.tuberculosis_H37Rv AAAAAGTTGLLAAG-ADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQ
MMAR_1162|M.marinum_M AAATVPTTNLLAAG-TDEISTAVASLFSGHGQAYQRLANQLMAFHDQFAQ
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
MUL_3507|M.ulcerans_Agy99 MSVAAPTAGVLAAG-ADEVSVAMAALFSGHGQAYQTLSAQANAFHAQFLQ
MLBr_01183|M.leprae_Br4923 ---------------------------------MPLFLN----AEPQALT
MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL
MAV_4827|M.avium_104 IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA
Mb3402|M.bovis_AF2122/97 ALTGAGGSYALTEAAN------VQQNLLNAINAPTQAL-----LGRPLIG
Rv3367|M.tuberculosis_H37Rv ALTGAGGSYALTEAAN------VQQNLLNAINAPTQAL-----LGRPLIG
MMAR_1162|M.marinum_M ALTAGASAYTGAEATNASPLQTVEQNALGLINAPTQTL-----LGRPLIG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR----------------TTD
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
MUL_3507|M.ulcerans_Agy99 ALTNAGGAYAAAEVANLSPLQGVEQGVLGVVNAPAQAL-----LGRPLIG
MLBr_01183|M.leprae_Br4923 AAANTLEGLSAATVAS------------------------------NAAA
MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTT
MAV_4827|M.avium_104 ALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT
.
Mb3402|M.bovis_AF2122/97 DGAVGTASSPDGQDGGLLFGNGGAGYNSAATPGMAGG-------------
Rv3367|M.tuberculosis_H37Rv DGAVGTASSPDGQDGGLLFGNGGAGYNSAATPGMAGG-------------
MMAR_1162|M.marinum_M DGAAGTATNPNGGAGGLLYGNGGAGFNNGATAGAAGG-------------
TH_3810|M.thermoresistible__bu NNALDGGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG--------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
MUL_3507|M.ulcerans_Agy99 DGAAGTAASPNGGAGGLLYGNGGAGYSYTSGATAEAG-------------
MLBr_01183|M.leprae_Br4923 AQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQG-------------
MAB_4284c|M.abscessus_ATCC_199 AIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN-------------
MAV_4827|M.avium_104 LAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-------------
.
Mb3402|M.bovis_AF2122/97 ----NGGNAGLIGNGGTGGSGGAGAAGGAGGSGG----------------
Rv3367|M.tuberculosis_H37Rv ----NGGNAGLIGNGGTGGSGGAGAAGGAGGSGG----------------
MMAR_1162|M.marinum_M ----NGGNAGLIGNGGAGGNGGAGAAGGTGGNGG----------------
TH_3810|M.thermoresistible__bu --VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
MUL_3507|M.ulcerans_Agy99 ---GNGGAAGLIGNGGAGGSGWAGGAGGAGGNGG----------------
MLBr_01183|M.leprae_Br4923 ----ATNHQDLIQSLLTSSSAYAGTETANHDSL-----------------
MAB_4284c|M.abscessus_ATCC_199 --ADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS--------------
MAV_4827|M.avium_104 ----LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLD------------
.
Mb3402|M.bovis_AF2122/97 -----------------WLYGNGGNGGIG----------------GNAIV
Rv3367|M.tuberculosis_H37Rv -----------------WLYGNGGNGGIG----------------GNAIV
MMAR_1162|M.marinum_M -----------------WLYGSGGAGGAG----------------GNALV
TH_3810|M.thermoresistible__bu --------------------------------------------QGEDGE
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
MUL_3507|M.ulcerans_Agy99 -----------------WLYGNGGAGGLG----------------GAAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------VTVVDDHSQRNTTN---------------INDSFN
MAV_4827|M.avium_104 ----------------VSVAEEPETALAR----------------GAALA
Mb3402|M.bovis_AF2122/97 AGGAGGNGGAGGAAG--------------LWGSGGSGGQGGNGLTGNDGV
Rv3367|M.tuberculosis_H37Rv AGGAGGNGGAGGAAG--------------LWGSGGSGGQGGNGLTGNDGV
MMAR_1162|M.marinum_M AGGTGGNGGAGGAAG--------------LWGNGGAGGHGGSGLAGNSGV
TH_3810|M.thermoresistible__bu DGTGTGIGGRGGNG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
MUL_3507|M.ulcerans_Agy99 DYTAGGVGGAGGNAG--------------LWGDGGAGGNGSATYDYDQN-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TDRSTNIGSGNTTNTEIG-----------SHNQANIGTSTSAGGSAAVGG
MAV_4827|M.avium_104 AANAPLFASSTAALAYAQ-----------DPGTGAVDQYSLPDYLYVPVD
Mb3402|M.bovis_AF2122/97 N-----------PAPVTNPALNGAAGDSNI--------------------
Rv3367|M.tuberculosis_H37Rv N-----------PAPVTNPALNGAAGDSNI--------------------
MMAR_1162|M.marinum_M N-----------PTPTHDTALNGADGDSNIY-------------------
TH_3810|M.thermoresistible__bu ------------------GSSSGTHPMAEDG-------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
MUL_3507|M.ulcerans_Agy99 --------------FSRLGALEGAGGNGGHG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 N-----------AGLAGNAGLAGNAGLAGNAG------------------
MAV_4827|M.avium_104 P-----------EPGDDELAYSAVGEEDAESP------------------
Mb3402|M.bovis_AF2122/97 -EPQTSVLIGTQGGDGTPGG-------------------------AGVNG
Rv3367|M.tuberculosis_H37Rv -EPQTSVLIGTQGGDGTPGG-------------------------AGVNG
MMAR_1162|M.marinum_M -DAATNTVSATPGTDGTPGG-------------------------AGVTG
TH_3810|M.thermoresistible__bu -----EHVKALDGRPGLDGG----------------------------NG
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
MUL_3507|M.ulcerans_Agy99 ------GLLFGNGGGGGDAGANNKFVT-------------------AQAT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAG-------------------LAGNA
MAV_4827|M.avium_104 -TVVIEKLFLPEDSEPRRRPVLLVG---------------------SGLA
Mb3402|M.bovis_AF2122/97 GNGGAGGDANGNPANT----------------------------------
Rv3367|M.tuberculosis_H37Rv GNGGAGGDANGNPANT----------------------------------
MMAR_1162|M.marinum_M GNGGAGGSAS-QPVTS----------------------------------
TH_3810|M.thermoresistible__bu SHGGNGGHGGRGGFLG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
MUL_3507|M.ulcerans_Agy99 PNGAAGGYGGNAGLWG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----------------------------------
MAV_4827|M.avium_104 VVGISAVLALEIALAIG---------------------------------
Mb3402|M.bovis_AF2122/97 ---------SIANAGAGGNGAAGGDGGANGGAGGAGG-------------
Rv3367|M.tuberculosis_H37Rv ---------SIANAGAGGNGAAGGDGGANGGAGGAGG-------------
MMAR_1162|M.marinum_M ---------LTATASDGGNGAQGGQGGADGGTGGVAG-------------
TH_3810|M.thermoresistible__bu ------------IGGSGGWGGHGGNGGDTDADGGNGG-------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
MUL_3507|M.ulcerans_Agy99 ------------NGGAGGDGGFGGTAT-VIGDGGTGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104 ----------IRTTGTVALQPTPNQHLIVPTEQAPAP-------------
Mb3402|M.bovis_AF2122/97 --------------------------------QAAS-AGSSVGGDGGNGG
Rv3367|M.tuberculosis_H37Rv --------------------------------QAAS-AGSSVGGDGGNGG
MMAR_1162|M.marinum_M --------------------------------VAASYNGVAIGGNGGNGG
TH_3810|M.thermoresistible__bu -----------------------------------------DGGNGGSAG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG
MUL_3507|M.ulcerans_Agy99 -------------------------------------NGGLLSGDGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------AGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 -----------------------------PPVQASAPQPKISVPEPVAAP
Mb3402|M.bovis_AF2122/97 AGGTGTNGHAGGAGGAGGQAASAGSSVGGDGGNGGAGGTGTNGHAGGAGG
Rv3367|M.tuberculosis_H37Rv AGGTGTNGHAGGAG-----------------------------------G
MMAR_1162|M.marinum_M TGGTGTDGLAGSGG-----------------------------------G
TH_3810|M.thermoresistible__bu RGGTGGLRGVFGIN------------------------------------
Mflv_5091|M.gilvum_PYR-GCK KGGTGGTGGAGGTG--------GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 KGGTGGTGGDGGTG--------GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 RGGDGALGGNGGTGGVG----LGNGGKGGNGGNGGNGGTYVDPSHTGAGG
MUL_3507|M.ulcerans_Agy99 VGGTGGIQIYSGGGIG------------------------------GVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG-----------------------------NAAV
MAV_4827|M.avium_104 KPLSPPVAAPLPAAPPP--------------------------------A
Mb3402|M.bovis_AF2122/97 AGGAGGRG---------------------------GWLVGSGGNGG----
Rv3367|M.tuberculosis_H37Rv AGGAGGRG---------------------------GWLVG---NGG----
MMAR_1162|M.marinum_M SGGAGGRG---------------------------GWLIGNGGAGG----
TH_3810|M.thermoresistible__bu -GGNGRAG-----------------------------LGGRGXXXX----
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
MUL_3507|M.ulcerans_Agy99 IGGNGGAG---------------GTSG----------LIGDGGAGG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAAVAG--------------------------NAAVAGNAAVGG----
MAV_4827|M.avium_104 APPLPEAP---------------------------PIPAAPPVVPVPVVV
Mb3402|M.bovis_AF2122/97 -------------NGGNG--------------------------------
Rv3367|M.tuberculosis_H37Rv -------------NGGNG--------------------------------
MMAR_1162|M.marinum_M -------------AGGAG--------------------------------
TH_3810|M.thermoresistible__bu -------------GGGVG--------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
MUL_3507|M.ulcerans_Agy99 -------------AGGTGGGNAGVGGVGG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------VLNTGVSGAIGGSSHVGGAIN----------------------
MAV_4827|M.avium_104 PPVPVPVPVRIPVPDPVSPPQLLAPPRLSVP-------------------
Mb3402|M.bovis_AF2122/97 ------------------------------------AAGGNGAIGGTGGA
Rv3367|M.tuberculosis_H37Rv ------------------------------------AAGGNGAIGGTGGA
MMAR_1162|M.marinum_M ------------------------------------GAGGNGAIGGDGGA
TH_3810|M.thermoresistible__bu -------------------------------------AAVRSGNGVFSGG
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
MUL_3507|M.ulcerans_Agy99 -------------------------------------VGGTGGAARLFGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------ESLGGSGSVGGSTAV
MAV_4827|M.avium_104 -----------------------------------QPVQPPVRVPQPPSP
Mb3402|M.bovis_AF2122/97 GGVP-ANQGGNSALGTQPVSGDGGDGGNGG--TGGTGGRGGDGG------
Rv3367|M.tuberculosis_H37Rv GGVP-ANQGGNSALGTQPVGGDGGDGGNGG--TGGTGGRGGDGG------
MMAR_1162|M.marinum_M AGFTGSNNDSAASTLYGAHGGTGGDGGAGG--TGGHGGAGGAGG------
TH_3810|M.thermoresistible__bu GGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS-----------
Mflv_5091|M.gilvum_PYR-GCK GGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GS
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQS
MUL_3507|M.ulcerans_Agy99 GGSGGIGGTGGHS-LINSGGGIGGKGGGGG--AAGLIGDGGAGG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG------
MAV_4827|M.avium_104 PQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGG------
Mb3402|M.bovis_AF2122/97 ----SGGAGGASGWLMGNGGNGGNGGTGGSG---------------GVGG
Rv3367|M.tuberculosis_H37Rv ----SGGAGGASGWLMGNGGNGGNGGTGGSG---------------GVGG
MMAR_1162|M.marinum_M ----AGGVGGDGGWLIGDGGAGGQGGIGGMG---------------GTGG
TH_3810|M.thermoresistible__bu ---ARAGAACASSTSRSRRSFCCSRA------------------------
Mflv_5091|M.gilvum_PYR-GCK GSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG
MSMEG_0868|M.smegmatis_MC2_155 GYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA
MUL_3507|M.ulcerans_Agy99 ----AGGNGGDGTGAGGLGGNGASADWIGNG---------------GSGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GAHTGVGGGVSTGVGVGSHVGGGISESLG---------------GSGS
MAV_4827|M.avium_104 ----SGGSGGGHVPTPGAGGSGGSGGGHVPTP--------------GTGG
Mb3402|M.bovis_AF2122/97 NGGIGGDGAGGGNATSTS-----------SIPFDAHGGNGGA--GGDAGH
Rv3367|M.tuberculosis_H37Rv NGGIGGDGAGGGNATSTS-----------SIPFDAHGGNGGA--GGDAGH
MMAR_1162|M.marinum_M AGGSGVAGAHGGNATSS---------------IAAFGGDGGA--GGDAGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
MUL_3507|M.ulcerans_Agy99 AGGSGGLGAHAGAGGNGG----------------SLYGNDGS--GGAGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGGGAHTGVGGG----------------VNTGVGVGSHVGGGIS
MAV_4827|M.avium_104 PGGTGGSGGGHVPTPGAG-------------------------TPGGSGG
Mb3402|M.bovis_AF2122/97 GGTGGDGGDGGHAGTG----------GRGGLLAGQHANSGNGGGGGTGG-
Rv3367|M.tuberculosis_H37Rv GGTGGDGGDGGHAGTG----------GRGGLLAGQHANSGNGGGGGTGG-
MMAR_1162|M.marinum_M GGMGGDGGNGGQGASG----------GRGGLLSGAQGVTGTAGDGGTGG-
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
MUL_3507|M.ulcerans_Agy99 GASGAGGNGGGGGAAG--------MMGDGGAGGDGGDGSAAGGLGGDGG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVG-------------GGAHTSAINDALGGSGSVGG-
MAV_4827|M.avium_104 GHLPFPGAGSTPGGSG------------GGHLPTPGAGTPGGGLGGFGG-
Mb3402|M.bovis_AF2122/97 ----------AGGTHGTPGSGNAGGTGTG--------NADSTNGGPGSDG
Rv3367|M.tuberculosis_H37Rv ----------AGGTHGTPGSGNAGGTGTG--------NADSTNGGPGSDG
MMAR_1162|M.marinum_M ----------AGGLHGAFGAG--GDPGTG--------GGQGSDGKLGADG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT
MUL_3507|M.ulcerans_Agy99 -----------NADWLGNGGGGTGGFGLP--------PATGGFGGRGGRL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHG
MAV_4827|M.avium_104 ------------GHAPAPGGGLGGGGGHAP----------APGGGLGGFG
Mb3402|M.bovis_AF2122/97 LGGDAFNGSRGTDGNPG----------------
Rv3367|M.tuberculosis_H37Rv LGGDAFNGSRGTDGNPG----------------
MMAR_1162|M.marinum_M LGGAAFDGARGADGNPG----------------
TH_3810|M.thermoresistible__bu ---------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MUL_3507|M.ulcerans_Agy99 FGSPGAQGRRALMCLSAACRC------------
MLBr_01183|M.leprae_Br4923 ---------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 GGHSGGGLGGLGGGHK-----------------