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SYVLAAPDAMATAASSVTNIGGALSAANAMATAPTTGVLAAAADEISVAMASVFSDHALSYQQVAARMAA FHDQFVAALHSGAGAYLTAETANASPLGTLEQRLLQAINAPTQTLLGRPLIGDGAAGTATNPNGGAGGLL YGNGGAGFNNGATAGAAGGNGGNAGLFGSGGAGGSGGAGAAGGAGGSGGWLYGSGGNGGSGGNAVIAGGN GGAGGAGGAAGLWGAGGNGGQGGSGLAGSNGVNPAAVTDPALNGAAGDSNINGNTTWHGTNGDPGTPGGT GVNGGNGGAGGDANDDVANSSGGLAGSGGSGATGGDGGANGGTGGAGGQAASYGYSSGGNGGTGGAGGTG ADGGAGGDGGHGGAGGRGGWLLGDGGNGGAGGDGATGGSGATGGNGGAGGITTADQNGYSAVGTQAVGGD GGNGGNGGSGGSGGTGGAAGSGGAGGDGGWLVGNGGTGGTGGIGGQGGIGGQGGVGGNGAVGGNAHSPIL DAHGGDGGAGGDAGHGGTGGDGGDGGLSGAGGRGGLLAGLQGSTGSGGAGGTGGDGGSPGTVGSGKAGGT GTGDGNSTNGGPGANGLGGAAFDGARGADGNPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1161 | - | - | 100% (594) | PE-PGRS family protein |
| M. marinum M | MMAR_1162 | - | 0.0 | 67.67% (597) | PE-PGRS family protein |
| M. marinum M | MMAR_4270 | - | e-171 | 52.76% (633) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3402 | PE_PGRS51 | 0.0 | 67.46% (633) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-113 | 46.84% (538) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3367 | PE_PGRS51 | 0.0 | 70.90% (598) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-11 | 34.38% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-50 | 35.40% (452) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-21 | 44.24% (165) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-91 | 37.99% (687) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-44 | 41.05% (285) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2354 | - | 1e-154 | 47.34% (659) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-112 | 45.50% (556) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1161|M.marinum_M --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_2354|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLLAA
Rv3367|M.tuberculosis_H37Rv --------MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLLAA
MMAR_1161|M.marinum_M --------MSYVLAAPDAMATAASSVTNIGGALSAANAMATAPTTGVLAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTG-SEATEP-
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATS-TNTTDQP
MUL_2354|M.ulcerans_Agy99 --------MWYLSVAPDELAAAATELRGVGSIVSTVNAAAAVPTTALWPA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVG
MAV_4827|M.avium_104 --------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDA
Mb3402|M.bovis_AF2122/97 GADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTGAGGSYALTEA
Rv3367|M.tuberculosis_H37Rv GADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTGAGGSYALTEA
MMAR_1161|M.marinum_M AADEISVAMASVFSDHALSYQQVAARMAAFHDQFVAALHSGAGAYLTAET
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------MVTFGGGATPT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------WYVVSFGGSGAPT
MSMEG_0868|M.smegmatis_MC2_155 TSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPN
MUL_2354|M.ulcerans_Agy99 AADEVSAAIAALFSSHAQQYQSLSVQVAAYHDQFVRALAAGGASYSLAEA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP
MAV_4827|M.avium_104 ATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR
Mb3402|M.bovis_AF2122/97 AN-----------------------------------------VQQNLLN
Rv3367|M.tuberculosis_H37Rv AN-----------------------------------------VQQNLLN
MMAR_1161|M.marinum_M ANASP-----------------------------------LGTLEQRLLQ
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK P----------------------------------------TSLGAAAVD
Mvan_1264|M.vanbaalenii_PYR-1 P----------------------------------------NNLAASLVD
MSMEG_0868|M.smegmatis_MC2_155 APTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLD
MUL_2354|M.ulcerans_Agy99 AS---------------------------------------ASPLEQLLD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLLSPRD---------------------------------NDFLSHNDTD
MAV_4827|M.avium_104 RIDN-------------------------------------VMLVSAFLA
Mb3402|M.bovis_AF2122/97 AIN--------------------APTQALLG--------RPLIGDGAVGT
Rv3367|M.tuberculosis_H37Rv AIN--------------------APTQALLG--------RPLIGDGAVGT
MMAR_1161|M.marinum_M AIN--------------------APTQTLLG--------RPLIGDGAAGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK LS------------------------GTSCG----------LICNGQDGT
Mvan_1264|M.vanbaalenii_PYR-1 LS------------------------GTSCG----------LICNGQDGT
MSMEG_0868|M.smegmatis_MC2_155 PTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGT
MUL_2354|M.ulcerans_Agy99 LIN--------------------LPSQTLLG--------RPLIGDGADGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FASHN----------------PIASGNQVMS---------PSGNVDSFNR
MAV_4827|M.avium_104 AAALAQN------------------VGGAMG---------YERTAVLLVE
Mb3402|M.bovis_AF2122/97 ASSPDGQDGGLLFGNGGAGYNSAATPGMAGGNGG----NAGLIG-NGGTG
Rv3367|M.tuberculosis_H37Rv ASSPDGQDGGLLFGNGGAGYNSAATPGMAGGNGG----NAGLIG-NGGTG
MMAR_1161|M.marinum_M ATNPNGGAGGLLYGNGGAGFNNGATAGAAGGNGG----NAGLFG-SGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GQN-----GGILFGNGGSGWN-SDVVGMDGGNGG----NGGLFGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1 GQN-----GGILFGNGGSGWN-SEIAGVSGGNGG----NAGLFGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYD-GSAAGLAGGNGG----NAGLFG-NGGNG
MUL_2354|M.ulcerans_Agy99 ASAPNGGAGGLLYGNGGNGYDNSASAGVAGGAGG----SAGLVG-NGGIG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR
MAV_4827|M.avium_104 PDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG---QLSAMVAGLEKLE
Mb3402|M.bovis_AF2122/97 GSGGAGAAGGAGGSGG--WLYGNGGNGGIGGNAIVAG---------GAGG
Rv3367|M.tuberculosis_H37Rv GSGGAGAAGGAGGSGG--WLYGNGGNGGIGGNAIVAG---------GAGG
MMAR_1161|M.marinum_M GSGGAGAAGGAGGSGG--WLYGSGGNGGSGGNAVIAG---------GNGG
TH_3810|M.thermoresistible__bu ----VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGG
Mflv_5091|M.gilvum_PYR-GCK GNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAG
Mvan_1264|M.vanbaalenii_PYR-1 GNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAG
MSMEG_0868|M.smegmatis_MC2_155 GVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGG
MUL_2354|M.ulcerans_Agy99 GAGGALAAGGAGGTGG--LLFGNGGSSGAGGLG-------------AVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQR
MAV_4827|M.avium_104 SLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALAR----GAAL
Mb3402|M.bovis_AF2122/97 NGGAGGAAG--------------------LWGSGGSGGQGG---------
Rv3367|M.tuberculosis_H37Rv NGGAGGAAG--------------------LWGSGGSGGQGG---------
MMAR_1161|M.marinum_M AGGAGGAAG--------------------LWGAGGNGGQGG---------
TH_3810|M.thermoresistible__bu HGGGTGIIS--------------------LLSLAGNGGNGG---------
Mflv_5091|M.gilvum_PYR-GCK ATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1 ATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG---------
MSMEG_0868|M.smegmatis_MC2_155 TGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLI
MUL_2354|M.ulcerans_Agy99 QGGGAGTLS--------------------LVGSGGDGGHGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NTTNINDSFN-----------------TDRSTNIGSGNTTN---------
MAV_4827|M.avium_104 AAANAPLFAS----------------STAALAYAQDPGTGAVDQYS----
Mb3402|M.bovis_AF2122/97 ------NGLTGNDGVNPAPVTNP---------------------------
Rv3367|M.tuberculosis_H37Rv ------NGLTGNDGVNPAPVTNP---------------------------
MMAR_1161|M.marinum_M ------SGLAGSNGVNPAAVTDP---------------------------
TH_3810|M.thermoresistible__bu ------NGYRTTDNNALDGGHGG---------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------
Mvan_1264|M.vanbaalenii_PYR-1 -----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------
MSMEG_0868|M.smegmatis_MC2_155 AGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANG
MUL_2354|M.ulcerans_Agy99 -----------EGTPGGSGGTGG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----TEIGSHNQANIGTSTSAGG---------------------------
MAV_4827|M.avium_104 ------LPDYLYVPVDPEPGDDE---------------------------
Mb3402|M.bovis_AF2122/97 -----------------------------------------------ALN
Rv3367|M.tuberculosis_H37Rv -----------------------------------------------ALN
MMAR_1161|M.marinum_M -----------------------------------------------ALN
TH_3810|M.thermoresistible__bu ------------------------------------------------NG
Mflv_5091|M.gilvum_PYR-GCK ------AVGAAGAAG------TVGTAGATGGTG---------------TG
Mvan_1264|M.vanbaalenii_PYR-1 ------AIGTAGVAG------AAGTAGATGGTG---------------VG
MSMEG_0868|M.smegmatis_MC2_155 GTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG
MUL_2354|M.ulcerans_Agy99 -------------------------------------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------SAAVG
MAV_4827|M.avium_104 -------------------------------------------LAYSAVG
Mb3402|M.bovis_AF2122/97 GAAGDSNIEPQTSVL------------------IGTQGGDGTPGGAGVNG
Rv3367|M.tuberculosis_H37Rv GAAGDSNIEPQTSVL------------------IGTQGGDGTPGGAGVNG
MMAR_1161|M.marinum_M GAAGDSNIN-GNTTW------------------HGTNGDPGTPGGTGVNG
TH_3810|M.thermoresistible__bu GNVGFFSLFNLGG--------------------AGGWGGSGVDG------
Mflv_5091|M.gilvum_PYR-GCK ANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVG
MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAG
MUL_2354|M.ulcerans_Agy99 GSAGLFGRGGFGG--------------------SGGTGGDGVVGSPAALD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGN-------------------AGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104 EEDAESPTVVIEKLFLPED-------------SEPRRRPVLLVGSGLAVV
Mb3402|M.bovis_AF2122/97 G--------------NGGAGGDANGNPANTSIANAG--------------
Rv3367|M.tuberculosis_H37Rv G--------------NGGAGGDANGNPANTSIANAG--------------
MMAR_1161|M.marinum_M G--------------NGGAGGDANDDVANSSGGLAG--------------
TH_3810|M.thermoresistible__bu ---------------VDVVGGNP---------------------------
Mflv_5091|M.gilvum_PYR-GCK GVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----
Mvan_1264|M.vanbaalenii_PYR-1 GIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----
MSMEG_0868|M.smegmatis_MC2_155 GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
MUL_2354|M.ulcerans_Agy99 G-------------GAGGTGGSGGRGGLFAVGG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 N--------------AGLAGNAGLAGNAGLAGNAG---------------
MAV_4827|M.avium_104 GISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPT--------------
Mb3402|M.bovis_AF2122/97 ---------------AGGNGAAGGDG------------------------
Rv3367|M.tuberculosis_H37Rv ---------------AGGNGAAGGDG------------------------
MMAR_1161|M.marinum_M ---------------SGGSGATGGDG------------------------
TH_3810|M.thermoresistible__bu ---------------DGGTPG-----------------------------
Mflv_5091|M.gilvum_PYR-GCK --------LQGGKGGDGGAGGKGGDADSMGS------------------A
Mvan_1264|M.vanbaalenii_PYR-1 --------LQGGQGGDGGTGGTGGDATSMGE------------------A
MSMEG_0868|M.smegmatis_MC2_155 KASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAA
MUL_2354|M.ulcerans_Agy99 ---------------DGGHGGIGGN-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------LAGNAGLAGNAG----------------------L
MAV_4827|M.avium_104 ---------------EQAPAPPPVQAS-----------------------
Mb3402|M.bovis_AF2122/97 GANGGAGGAGGQAASAGSSV------------------------------
Rv3367|M.tuberculosis_H37Rv GANGGAGGAGGQAASAGSSV------------------------------
MMAR_1161|M.marinum_M GANGGTGGAGGQAASYGYSS------------------------------
TH_3810|M.thermoresistible__bu -AHGESHTPGVYTDRQ----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-----
Mvan_1264|M.vanbaalenii_PYR-1 GATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-----
MSMEG_0868|M.smegmatis_MC2_155 SANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQA
MUL_2354|M.ulcerans_Agy99 GARGADGVGDGESGTAGGNG------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAG------------------------------
MAV_4827|M.avium_104 APQPKISVPEPVAAPKPLSP------------------------------
Mb3402|M.bovis_AF2122/97 -----------------GGDGGNGGAGGTGT-NGHAGGAGGAGGQAASAG
Rv3367|M.tuberculosis_H37Rv -----------------GGDGGNGGAGGTGT-NGHAGGAG----------
MMAR_1161|M.marinum_M -----------------GGNGGTGGAGGTGA-DGGAGGDG----------
TH_3810|M.thermoresistible__bu ---------------------GEDGEDGTGTGIGGRGGNGG---------
Mflv_5091|M.gilvum_PYR-GCK -----------------GGTGGAGGAGGTGG-TGGAGGTGG---------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GGTGGNGGNGGTGG-TGGNGGTGG---------
MSMEG_0868|M.smegmatis_MC2_155 YDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANG
MUL_2354|M.ulcerans_Agy99 ------------------GAGGAGGVGGTGISSGSDGVGGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAGLAGNAGLAGN---------
MAV_4827|M.avium_104 --------------------PVAAPLPAAPPPAAPPLPEAP---------
Mb3402|M.bovis_AF2122/97 ---SSVGGDGGNGGAGGTGTNGHAGGAGGAGGAGGRGGWLV--GSGGNGG
Rv3367|M.tuberculosis_H37Rv ----------------------------GAGGAGGRGGWLV--G---NGG
MMAR_1161|M.marinum_M ----------------------------GHGGAGGRGGWLL--GDGGNGG
TH_3810|M.thermoresistible__bu -------SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGS
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 QHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGG
MUL_2354|M.ulcerans_Agy99 ---------GGNGGRGGDGIR------GADGVLDCESGYL-----GGSGG
MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFL---------N
MAB_4284c|M.abscessus_ATCC_199 ------------------------AGLAGNAGLAGNAGLAGNAAVAGNAA
MAV_4827|M.avium_104 -------------PIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQL
Mb3402|M.bovis_AF2122/97 NGGNGAAGGNGAIGGTGGAG-----GVP-ANQGGNSALG----------T
Rv3367|M.tuberculosis_H37Rv NGGNGAAGGNGAIGGTGGAG-----GVP-ANQGGNSALG----------T
MMAR_1161|M.marinum_M AGGDGATGGSGATGGNGGAG-----GITTADQNGYSAVG----------T
TH_3810|M.thermoresistible__bu HGGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------T
Mflv_5091|M.gilvum_PYR-GCK TGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GT
MSMEG_0868|M.smegmatis_MC2_155 HGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGA
MUL_2354|M.ulcerans_Agy99 AGGAGGAGGGGSQVGSDGVG-------GAGGAGGTGGAG-----------
MLBr_01183|M.leprae_Br4923 AEPQALTAAANTLEGLSAAT--------VASNAAAAQLT-----------
MAB_4284c|M.abscessus_ATCC_199 VAGNAAVAGNAAVGGVLNTG-------VSGAIGGSSHVGG-------AIN
MAV_4827|M.avium_104 LAPPRLSVPQPVQPPVRVPQ-----PPSPPQVGGTVPQS----------P
.
Mb3402|M.bovis_AF2122/97 QPVSGDGGDG---------------GNGGTGG------------------
Rv3367|M.tuberculosis_H37Rv QPVGGDGGDG---------------GNGGTGG------------------
MMAR_1161|M.marinum_M QAVGGDGGNG---------------GNGGSGG------------------
TH_3810|M.thermoresistible__bu DADGGNGGDG---------------GNGGSAG------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEA
MUL_2354|M.ulcerans_Agy99 -GHGARGADG------------LLDGEAGSKG------------------
MLBr_01183|M.leprae_Br4923 TEIAPPAADD----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVG---------------GSTAVGG------------------
MAV_4827|M.avium_104 PQHQTPPGEG---------------TPPKPDG------------------
. .
Mb3402|M.bovis_AF2122/97 ---------------TGGRGGDGG-SGGAGGAS-----------------
Rv3367|M.tuberculosis_H37Rv ---------------TGGRGGDGG-SGGAGGAS-----------------
MMAR_1161|M.marinum_M ---------------SGGTGGAAG-SGGAGGDG-----------------
TH_3810|M.thermoresistible__bu ---------------RGGTGGLRGVFGINGGNG-----------------
Mflv_5091|M.gilvum_PYR-GCK ---------------TGGTGGQGG-LGGGGGTG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------TGGTGGQGG-LGGVGGTG-----------------
MSMEG_0868|M.smegmatis_MC2_155 LIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQA
MUL_2354|M.ulcerans_Agy99 -----------------GAGGGGG-AGGAGGAG-----------------
MLBr_01183|M.leprae_Br4923 --------------------VSILLAHFFSGHG-----------------
MAB_4284c|M.abscessus_ATCC_199 ----------------GAHTGVGGGVSTGVGVG-----------------
MAV_4827|M.avium_104 ---------------PGNYGGGHVPTPGAGGSG-----------------
* .
Mb3402|M.bovis_AF2122/97 --------GWLMGNGGNGGNGGTGGSGGVG--------------GNGGIG
Rv3367|M.tuberculosis_H37Rv --------GWLMGNGGNGGNGGTGGSGGVG--------------GNGGIG
MMAR_1161|M.marinum_M --------GWLVGNGGTGGTGGIGGQGGIG--------------GQGGVG
TH_3810|M.thermoresistible__bu -------RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFS
Mflv_5091|M.gilvum_PYR-GCK ------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
Mvan_1264|M.vanbaalenii_PYR-1 ------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLG
MSMEG_0868|M.smegmatis_MC2_155 SGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDG
MUL_2354|M.ulcerans_Agy99 ------SQAGSDGVGGAGGDGGDGGHGAYG---------DGKAGGGGGAG
MLBr_01183|M.leprae_Br4923 -----------RQYQAHASQGATNHQDLIQ----------------SLLT
MAB_4284c|M.abscessus_ATCC_199 ------SHVGGGISESLGGSGSVGGSTAVG---------------GGAHT
MAV_4827|M.avium_104 -----------GSGGGHVPTPGAGGSGGSG-------------------G
. .
Mb3402|M.bovis_AF2122/97 GDGAGGGNATSTSSIPFDAHGG-NGGAGGDAG------------------
Rv3367|M.tuberculosis_H37Rv GDGAGGGNATSTSSIPFDAHGG-NGGAGGDAG------------------
MMAR_1161|M.marinum_M GNGAVGGNAHSP---ILDAHGG-DGGAGGDAG------------------
TH_3810|M.thermoresistible__bu GGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------------------
Mflv_5091|M.gilvum_PYR-GCK GLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----
Mvan_1264|M.vanbaalenii_PYR-1 GLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----
MSMEG_0868|M.smegmatis_MC2_155 GLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWV
MUL_2354|M.ulcerans_Agy99 GRGGDGGDGDTGGAAGNGGDGGEGGNAVANSG------------------
MLBr_01183|M.leprae_Br4923 SSSAYAGTETANHDSL----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGGGVSTGVGVGSHVGGGISESLGGSGSVGG------------------
MAV_4827|M.avium_104 GHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGG------------------
. .
Mb3402|M.bovis_AF2122/97 -------HGGTGGDGGDGG------------------------------H
Rv3367|M.tuberculosis_H37Rv -------HGGTGGDGGDGG------------------------------H
MMAR_1161|M.marinum_M -------HGGTGGDGGDGG------------------------------L
TH_3810|M.thermoresistible__bu ------IMPSSRAASARAG---------------------------AACA
Mflv_5091|M.gilvum_PYR-GCK GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGA
MSMEG_0868|M.smegmatis_MC2_155 QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGN
MUL_2354|M.ulcerans_Agy99 ------RGGGTGGAGGVGG----------------------------DGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----STAVGGGAHTGVGGGVN-------------------------TGVG
MAV_4827|M.avium_104 -------SGGGHLPFPGAG-------------------------------
Mb3402|M.bovis_AF2122/97 AGTGGRGG--LLAGQHANSG------------------------------
Rv3367|M.tuberculosis_H37Rv AGTGGRGG--LLAGQHANSG------------------------------
MMAR_1161|M.marinum_M SGAGGRGG--LLAGLQGSTG------------------------------
TH_3810|M.thermoresistible__bu SSTSRSRRSFCCSRA-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANG
Mvan_1264|M.vanbaalenii_PYR-1 SGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANG
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
MUL_2354|M.ulcerans_Agy99 NGTNGVGGAGGHGGMGGNAG--------------------SSDAANGAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGG-----------------------------
MAV_4827|M.avium_104 STPGGSGGGHLPTPGAGTPG------------------------------
Mb3402|M.bovis_AF2122/97 ------------------------------------------NGGGGGTG
Rv3367|M.tuberculosis_H37Rv ------------------------------------------NGGGGGTG
MMAR_1161|M.marinum_M ------------------------------------------SGGAGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 SQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNG
MUL_2354|M.ulcerans_Agy99 SRGGDGGDGGKGGQGTTG----------GDGGNGG-------SAGKGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------STAVGGGAHTSAINDALGGSGSVG
MAV_4827|M.avium_104 -------------------------------------------GGLGGFG
Mb3402|M.bovis_AF2122/97 G-----------AGGTHGTPGSGNAGGTGTG--------NADSTNGGPGS
Rv3367|M.tuberculosis_H37Rv G-----------AGGTHGTPGSGNAGGTGTG--------NADSTNGGPGS
MMAR_1161|M.marinum_M G-----------DGGSPGTVGSGKAGGTGTG--------DGNSTNGGPGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK G-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 G-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG
MSMEG_0868|M.smegmatis_MC2_155 GNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG
MUL_2354|M.ulcerans_Agy99 G-----------AAAQTNDAGDGGDGGASST--------STGGAPGGVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G----------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGS
MAV_4827|M.avium_104 G-------------GHAPAPGGGLGGGGGHAP----------APGGGLGG
Mb3402|M.bovis_AF2122/97 DGLGGDAFNGSRGTDGNPG----------------
Rv3367|M.tuberculosis_H37Rv DGLGGDAFNGSRGTDGNPG----------------
MMAR_1161|M.marinum_M NGLGGAAFDGARGADGNPG----------------
TH_3810|M.thermoresistible__bu -----------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 SGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MUL_2354|M.ulcerans_Agy99 DGDDGDPPTGQTGGGGTGGGGGAPGVV--------
MLBr_01183|M.leprae_Br4923 -----------------------------------
MAB_4284c|M.abscessus_ATCC_199 HGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 FGGGHSGGGLGGLGGGHK-----------------