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SKTAKRLGPQDMFFLYSESPSTMMHVGALMPFTPPDDAPADFLRQLVDESKANEVVEPWNLKLSHPDLLY SPTQSWVYDENFDLDYHVRRSALASPGDERELGILVSRLHSHALDLRRPPWEMHFIEGLEGGRFAIYIKM HHSLIDGYTGQKMLARSLSADPHDTTHPLFFNIPTPGPAPADTEESAGGGLIGGAGNVLSGLGDVVKGLG SMVSGVGSVLGSVASAGRSSLDLTRALVNSQLRTDNEYRDLVSSVQAPHCILNTRISRNRRFATQQYPLA RMKAIGAQYDATVNDVAMAIIGGGLRRFLDELGELPDKSLIAVLPVNVRPKDDEGGGNAVATILATLGTD IADPVERLRAVTASTRMAKAQLKNMDRDAILAYSAALMVPYGIQLASTLTGVKPPLPYTFNLCVSNVPGP QEVLYLRGSRMEASYPVSLVAHSQALNVTLQSYAGTLNFGFIGCRDTLPHLQRLAVYTGEALDELDEPAA ASAVN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4955 | - | - | 100% (496) | hypothetical protein MMAR_4955 |
| M. marinum M | MMAR_5271 | - | 1e-89 | 39.63% (482) | hypothetical protein MMAR_5271 |
| M. marinum M | MMAR_5278 | - | 9e-81 | 37.92% (480) | hypothetical protein MMAR_5278 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3509c | - | 1e-133 | 88.59% (263) | hypothetical protein Mb3509c |
| M. gilvum PYR-GCK | Mflv_1058 | - | 1e-172 | 61.19% (487) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3480c | - | 0.0 | 88.07% (486) | hypothetical protein Rv3480c |
| M. leprae Br4923 | MLBr_01244 | - | 1e-24 | 27.95% (365) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 2e-77 | 36.16% (484) | hypothetical protein MAB_4544c |
| M. avium 104 | MAV_0355 | - | 8e-83 | 38.80% (482) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 2e-86 | 38.98% (490) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 9e-80 | 38.43% (484) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1193 | - | 2e-80 | 36.96% (487) | hypothetical protein MUL_1193 |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 1e-165 | 60.55% (474) | hypothetical protein Mvan_5773 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3509c|M.bovis_AF2122/97 --------------------------------------------------
Rv3480c|M.tuberculosis_H37Rv MSQTARRLGPQDMF----FLYSESSTTMMHVGALMPFTPP-SGAPPDLLR
MMAR_4955|M.marinum_M MSKTAKRLGPQDMF----FLYSESPSTMMHVGALMPFTPP-DDAPADFLR
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
Mvan_5773|M.vanbaalenii_PYR-1 -------------M----FIYGETSSSKMHVAGLLPFTPP-ADAPRDYLR
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MUL_1193|M.ulcerans_Agy99 ----MELMMPTDAS----FLFTESREHPMHVAGLQLFDPP-DAAGPGFVD
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFR
Mb3509c|M.bovis_AF2122/97 --------------------------------------------------
Rv3480c|M.tuberculosis_H37Rv QLVDESKASEVVEPWSLRLSHPELLYHPTQSWVVDDNFDLDYHVRRSALA
MMAR_4955|M.marinum_M QLVDESKANEVVEPWNLKLSHPDLLYSPTQSWVYDENFDLDYHVRRSALA
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSALA
Mvan_5773|M.vanbaalenii_PYR-1 RMVDDARRQEVMPPWNRKLAYPRLQFSPLHTWVTDTEFDFDYHVRRSALA
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRHTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSALP
TH_2030|M.thermoresistible__bu GLHQRLAAGRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSALP
MAV_0355|M.avium_104 DFYKQLVAQPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSALP
MUL_1193|M.ulcerans_Agy99 EIYRCLAANREGQPAFRKHPATLLGGITNLGWQYDNEIDTDYHVRRSVLP
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSALP
MLBr_01244|M.leprae_Br4923 SRIEDVSQR---VLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVP
Mb3509c|M.bovis_AF2122/97 --------------------------------------------------
Rv3480c|M.tuberculosis_H37Rv SPGDERELGIPVSRLHSHALDLRRPPWEVHFIEGLEGGRFAIYIKMHHSL
MMAR_4955|M.marinum_M SPGDERELGILVSRLHSHALDLRRPPWEMHFIEGLEGGRFAIYIKMHHSL
Mflv_1058|M.gilvum_PYR-GCK SPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
Mvan_5773|M.vanbaalenii_PYR-1 SPGDERELGILVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHAL
MSMEG_6322|M.smegmatis_MC2_155 SPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHSL
TH_2030|M.thermoresistible__bu GPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHAL
MAV_0355|M.avium_104 SPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHAL
MUL_1193|M.ulcerans_Agy99 YPGRVRELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHAL
MAB_4544c|M.abscessus_ATCC_199 RPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHAV
MLBr_01244|M.leprae_Br4923 DPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAI
Mb3509c|M.bovis_AF2122/97 --------------------------------------------------
Rv3480c|M.tuberculosis_H37Rv IDGYTGQKMLARSLSTDPHDTTHPLFFNIPTPGRSPADTQDSVGGGLIAG
MMAR_4955|M.marinum_M IDGYTGQKMLARSLSADPHDTTHPLFFNIPTPGPAPADTEESAGGGLIGG
Mflv_1058|M.gilvum_PYR-GCK VDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRSRRD----------PG
Mvan_5773|M.vanbaalenii_PYR-1 VDGYTAMRMLGRSLSTDPETRDARMFFNVPIPKRSRPT----------GA
MSMEG_6322|M.smegmatis_MC2_155 IDGVSAMKLVERTLSEDPSDTTVRVPWNLPRRESSRR------------A
TH_2030|M.thermoresistible__bu IDGVAVMKLMQRTLSTDPGDD-ARVPWNLPPPRRNP-------------A
MAV_0355|M.avium_104 IDGVSAQKLMQRALSSDPDDPEIRAPWTLP--KRSRK------------A
MUL_1193|M.ulcerans_Agy99 LDGASALMLLQRALSDDPRDTEVRAPWNLP--PQPDH------------A
MAB_4544c|M.abscessus_ATCC_199 IDGVGALRMMMRSLSDDPDARDCQAVWAPAKRRAKSS------------I
MLBr_01244|M.leprae_Br4923 TDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRND----------LM
Mb3509c|M.bovis_AF2122/97 ----------------------------MAGAGRSTFELTKALVNAQLRS
Rv3480c|M.tuberculosis_H37Rv AGNVLDGLGDVVRGLGGLVSGVGSVLGSVAGAGRSTFELTKALVNAQLRS
MMAR_4955|M.marinum_M AGNVLSGLGDVVKGLGSMVSGVGSVLGSVASAGRSSLDLTRALVNSQLRT
Mflv_1058|M.gilvum_PYR-GCK AAESSNPLTATLRALGGVSS-------AVTGGVSSAVDLTNALVNTQIRR
Mvan_5773|M.vanbaalenii_PYR-1 GAQSSNPVTATLRALGAVGS-------TVSDGVGSAVDLASALVNTQIRR
MSMEG_6322|M.smegmatis_MC2_155 GSSS------LARTATGAAT-------SLAALAPSTIRLARAALLEQQ--
TH_2030|M.thermoresistible__bu GPVS------RLRSATGAVG-------SVAALAPSTLSLARAALLEQR--
MAV_0355|M.avium_104 GPSS------RLSSLVHAAG-------SVAALAPSTVSLARAALVEQQ--
MUL_1193|M.ulcerans_Agy99 VGSS------RLGSLANTAG-------SLMALGPSTVSLIRAALVEQQ--
MAB_4544c|M.abscessus_ATCC_199 VSTTNTSAIDLVKGAAGAVR-------QVVSIPPGLLKYGRHALSDPQ--
MLBr_01244|M.leprae_Br4923 LQGINHLPVALAGGVVGGLS-------GVASVAGRAILRPASTVSGVVGY
: . :
Mb3509c|M.bovis_AF2122/97 DHEYRNLVGSVQAPHCILNTRISRNRRFATQQYPLDRLKAIGAQYDATIN
Rv3480c|M.tuberculosis_H37Rv DHEYRNLVGSVQAPHCILNTRISRNRRFATQQYPLDRLKAIGAQYDATIN
MMAR_4955|M.marinum_M DNEYRDLVSSVQAPHCILNTRISRNRRFATQQYPLARMKAIGAQYDATVN
Mflv_1058|M.gilvum_PYR-GCK DGENAHIAGSVSAPHSILNARISRNRRFATQQYEFDRLKKLSSQHGATLN
Mvan_5773|M.vanbaalenii_PYR-1 DGDFGRISGSASAPHSILNARISRNRRFATQQYEFDRLKKLSSQHGATIN
MSMEG_6322|M.smegmatis_MC2_155 ------LTLPFGAPRTMFNVKIGGARRVAAQSWPLERLRRIKAVTGATIN
TH_2030|M.thermoresistible__bu ------LTLPFGAPRTMFNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLN
MAV_0355|M.avium_104 ------LTLPFGAPRTMLNVKIGGARRCAAQSWPLERIKNVKNAAGVTVN
MUL_1193|M.ulcerans_Agy99 ------LTLPFGAPRTLFNVKVGGARRCAAQSWSLDRFRAVAKCAGVTIN
MAB_4544c|M.abscessus_ATCC_199 ------LVKPLSAPHTMLNVSIGGARRFAAQTWSMARIKEAGKALGGTVN
MLBr_01244|M.leprae_Br4923 VRSGIRVLSQAAEPSPLLRQRS-LATRTEAIEIQLSDLHKAAKAGDGSIN
: * ::. * : : :: . ::*
Mb3509c|M.bovis_AF2122/97 DVALAIIGGGLRRFLDELGELPNKSLIVVLPVNVRPKDD-EGGGNAVATI
Rv3480c|M.tuberculosis_H37Rv DVALAIIGGGLRRFLDELGELPNKSLIVVLPVNVRPKDD-EGGGNAVATI
MMAR_4955|M.marinum_M DVAMAIIGGGLRRFLDELGELPDKSLIAVLPVNVRPKDD-EGGGNAVATI
Mflv_1058|M.gilvum_PYR-GCK DVALAIIGGGLRKFLSDFDKLPDRSLIAFLPVNVRPKGD-EGGGNAVGAI
Mvan_5773|M.vanbaalenii_PYR-1 DVALAIIGGGLRKFLADLGELPDRSLIAFLPVNVRPKGD-EGGGNAVGAI
MSMEG_6322|M.smegmatis_MC2_155 DIVLAMCAGALRAYLAEQDALPDRPLIAMVPVSMRSEHEADAGGNMVGSI
TH_2030|M.thermoresistible__bu DVALAMCAGALRQYLLEHDALPATPLVAMVPVSLRSADESAGGGNRTGLV
MAV_0355|M.avium_104 DVVLAMCSGALRYYLLEQNALPDTPLIAMVPVSLRTEEEADAGGNLVGAI
MUL_1193|M.ulcerans_Agy99 DVVLAMCAGALRQYLLEQNALPDAPLVALVPVSLRSQTD-DSGDTMVGTV
MAB_4544c|M.abscessus_ATCC_199 DVVLAMCGGALRTYLEEQNALPDKPLVAMCPVSIRAEGDQNAGNSIT-AL
MLBr_01244|M.leprae_Br4923 DAYLAGLVGALRRYHEALGVSIS-TLPMAVPVNVRTEADVVGSNRFVGVT
* :* *.** : . .* **.:*. : ... .
Mb3509c|M.bovis_AF2122/97 LATLGTDVADPVQRLAAVTASTRAAKAQLRSMDKDAILAYSAALMAPYGV
Rv3480c|M.tuberculosis_H37Rv LATLGTDVADPVQRLAAVTASTRAAKAQLRSMDKDAILAYSAALMAPYGV
MMAR_4955|M.marinum_M LATLGTDIADPVERLRAVTASTRMAKAQLKNMDRDAILAYSAALMVPYGI
Mflv_1058|M.gilvum_PYR-GCK LAPMGTDIEDPVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGS
Mvan_5773|M.vanbaalenii_PYR-1 LAPMGTDIEDPVERLAVITAATRASKAQLQSMSPAAIIAYSAALLAPAGG
MSMEG_6322|M.smegmatis_MC2_155 LCSLGTDVEDPADRLAVIRRSITDNKRVFSELPRLQALALSALLIAP--L
TH_2030|M.thermoresistible__bu LCNLATDSDDPAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAP--L
MAV_0355|M.avium_104 LCNLATDSDDPAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSS--L
MUL_1193|M.ulcerans_Agy99 LCGLATDTTDPAKRLEMISQSMRRNKKAFSELSPLQAKALWAFNMAP--L
MAB_4544c|M.abscessus_ATCC_199 LANLATDKPDPLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAP--V
MLBr_01244|M.leprae_Br4923 LAAPLG-TNDPAARMQKIRSQMTQRR----DEPAMNIIGS----LAPLMT
*. ** *: : : . .
Mb3509c|M.bovis_AF2122/97 QLASTLSGVKPPWPYTFNLCVSNVPGPEDVLYLRGSRMEASYPVS-----
Rv3480c|M.tuberculosis_H37Rv QLASTLSGVKPPWPYTFNLCVSNVPGPEDVLYLRGSRMEASYPVS-----
MMAR_4955|M.marinum_M QLASTLTGVKPPLPYTFNLCVSNVPGPQEVLYLRGSRMEASYPVS-----
Mflv_1058|M.gilvum_PYR-GCK QIAGALTGVQPPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVS-----
Mvan_5773|M.vanbaalenii_PYR-1 QIAGALTGVNPPWPHTFNLCVSNVPGPREPLYFNGSRLEATFPVS-----
MSMEG_6322|M.smegmatis_MC2_155 GLTTAFPGFVDATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLS-----
TH_2030|M.thermoresistible__bu GLG-AVPGVVSSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLS-----
MAV_0355|M.avium_104 ALA-AVPGWVSATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLS-----
MUL_1193|M.ulcerans_Agy99 TLT-AVPGFVPWTKPSFNVIVSNLPGPTKPMYWHGARLDSIYPLS-----
MAB_4544c|M.abscessus_ATCC_199 LTG-AVPGLVDRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPAS-----
MLBr_01244|M.leprae_Br4923 VLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGV
:. . . :: **:*. : * .: : .
Mb3509c|M.bovis_AF2122/97 -----LVAHSQALNVTLQSYAGTLNFGFIGCRDTLPHLQRLAVYTGEALD
Rv3480c|M.tuberculosis_H37Rv -----LVAHSQALNVTLQSYAGTLNFGFIGCRDTLPHLQRLAVYTGEALD
MMAR_4955|M.marinum_M -----LVAHSQALNVTLQSYAGTLNFGFIGCRDTLPHLQRLAVYTGEALD
Mflv_1058|M.gilvum_PYR-GCK -----IPIHGMALNITLQSYADTMNLGFVGCRDRLPHLQRLAVYTGDALA
Mvan_5773|M.vanbaalenii_PYR-1 -----IPIHGMALNITLQSYADTMNLGFVGCRDRLPRLQRLAVYTGDALG
MSMEG_6322|M.smegmatis_MC2_155 -----IALDGQALNMTVVSNAHNLDFGLVGCRRSVPHLQRLLGHLETSLK
TH_2030|M.thermoresistible__bu -----IVLDGQALNITLVTNADNLDFGLVGARGSVPHLQRLLGHLEDSLQ
MAV_0355|M.avium_104 -----IVLDGQALNITLASNAGNLDFGLVGCRRSVPHLQRLLMHLESSLK
MUL_1193|M.ulcerans_Agy99 -----IAHDGQALSITLLSNAGTLEFGLVGCRRSVPHLQRLLLHLETSLY
MAB_4544c|M.abscessus_ATCC_199 -----IPIDGVALNITCTSSGSSMHFGLTGCRTSVPHLQRILAHLEDALT
MLBr_01244|M.leprae_Br4923 AMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTP
: . .:* .:. .* : ::.: .
Mb3509c|M.bovis_AF2122/97 QLAAADGAAGLGS---------
Rv3480c|M.tuberculosis_H37Rv QLAAADGAAGLGS---------
MMAR_4955|M.marinum_M ELDEPAAASAVN----------
Mflv_1058|M.gilvum_PYR-GCK ELEAASQI--------------
Mvan_5773|M.vanbaalenii_PYR-1 ELEAASS---------------
MSMEG_6322|M.smegmatis_MC2_155 DLETATGA--------------
TH_2030|M.thermoresistible__bu QLERAVGG--------------
MAV_0355|M.avium_104 DLERAVGE--------------
MUL_1193|M.ulcerans_Agy99 GLEQAVGL--------------
MAB_4544c|M.abscessus_ATCC_199 QLEESVA---------------
MLBr_01244|M.leprae_Br4923 HAVPASFAARSSGSPAGWLSSS
.