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M. marinum M MMAR_4953 (-)

annotation: PE-PGRS family protein
coordinates: 6015223 - 6016956
length: 577

SFVLVAPDMLATAAADVVQIGSAVSAGNLAAAIPTTEVMAAAADEVSGAIAALFGANAQEYQAAAAQAAT
FHEQFVRALSEAGASYASAEATIVTGLSSAVADGFQTAVYGPIRAAGQAWISSPAGEVVDPVINAPTEAL
FGRGLISNGAAGTAAHPNGGAGGILFGDGGPGYTPTGGIGAVAGGIGGDAGLIGNGGLGGNGFGGGTGGM
GGTGGWLMGNGGGGGVGGVGGVGGQALFFGNGGAGGGSALGGRAGLFIGEPGTGWVADPGNGQSIVIDFV
RHGQTASNVAELIDTNVPGPPLTAEGHLQADIIAGQLFAKGPYAGIFDSELLRTQQTAAPLAALYGITDV
PALSGLNEISAGIFDGLQQITPAGLLYLIGPMAWTLGYPIVPMLTPGSLDFNGVVFNQDFTHAMDTMYSA
ALANPVLAANGKITDVAYSSAFTIGVGTMMNVDNPDPLLLLTHPLPNTGVVEVQGSPANGWTMVSWDGIP
VAPATLPTQLFVDVRNLITAPQYAGWDIFYSLFTGNPTTILTAVRDGIEEVGSAVINFPIEVTEDVVNAI
CGATDGLTAGAPSLVG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4953--100% (577)PE-PGRS family protein
M. marinum MMMAR_3570-1e-6650.51% (295) PE-PGRS family protein
M. marinum MMMAR_3199-3e-6649.65% (284) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0776PE_PGRS110.066.95% (593) PE-PGRS family protein
M. gilvum PYR-GCKMflv_4577-4e-4942.16% (287) phosphoglycerate mutase
M. tuberculosis H37RvRv0754PE_PGRS110.066.95% (593) PE-PGRS family protein
M. leprae Br4923MLBr_01183-6e-1137.08% (89) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-1237.68% (138) hypothetical protein MAB_4284c
M. avium 104MAV_4778-2e-6855.51% (245) pe_pgrs family protein
M. smegmatis MC2 155MSMEG_0868-3e-3648.63% (183) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_4040-2e-4239.42% (274) PUTATIVE Phosphoglycerate mutase
M. ulcerans Agy99MUL_3507-5e-6648.01% (302) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_5262-6e-5442.33% (300) phosphoglycerate mutase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0776|M.bovis_AF2122/97            ------------MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTA
Rv0754|M.tuberculosis_H37Rv         ------------MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTA
MMAR_4953|M.marinum_M               ------------MSFVLVAPDMLATAAADVVQIGSAVSAGNLAAAIPTTE
Mflv_4577|M.gilvum_PYR-GCK          ----------------------------------------MPDPR--TCR
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       ----------------------------------------MRDVRRTARR
MAV_4778|M.avium_104                -------------------------------------------MLRTPLC
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MUL_3507|M.ulcerans_Agy99           ------------MSFVSVTQEALAAAASDVGVIGSSLQAANMSVAAPTAG
MAB_4284c|M.abscessus_ATCC_199      ---------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQV
                                                                                      

Mb0776|M.bovis_AF2122/97            VA---------------------------AAAADEVSAALAALFGAHARE
Rv0754|M.tuberculosis_H37Rv         VA---------------------------AAAADEVSAALAALFGAHARE
MMAR_4953|M.marinum_M               VM---------------------------AAAADEVSGAIAALFGANAQE
Mflv_4577|M.gilvum_PYR-GCK          VR---------------------------RILIAALSAVLLVLVSAIP--
TH_4040|M.thermoresistible__bu      ------------------------------VVVAAISAALLFIVSAIP--
Mvan_5262|M.vanbaalenii_PYR-1       LL---------------------------TILAATLAAAVLFAASAFA--
MAV_4778|M.avium_104                RA---------------------------GAVLASVVLLCSASATASA--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MUL_3507|M.ulcerans_Agy99           VL---------------------------AAGADEVSVAMAALFSGHGQA
MAB_4284c|M.abscessus_ATCC_199      GAVMP-----------------------VVAESVASNYGYQSQWVNTGNP
                                                                                      

Mb0776|M.bovis_AF2122/97            YQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSD
Rv0754|M.tuberculosis_H37Rv         YQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSD
MMAR_4953|M.marinum_M               YQAAAAQAATFHEQFVRALSEAGASYASAEATIVTGLS-------SAVAD
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MUL_3507|M.ulcerans_Agy99           YQTLSAQANAFHAQFLQALTNAGG-----------------------AYA
MAB_4284c|M.abscessus_ATCC_199      IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN------------DFLSHN
                                                                                      

Mb0776|M.bovis_AF2122/97            GFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGT
Rv0754|M.tuberculosis_H37Rv         GFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGT
MMAR_4953|M.marinum_M               GFQTAVYGPIRAAGQAWISSPAGEVVDPVINAPTEALFGRGLISNGAAGT
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MUL_3507|M.ulcerans_Agy99           AAEVANLS------------------------------PLQGVEQGVLG-
MAB_4284c|M.abscessus_ATCC_199      DTDFASHN------------------------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            AAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGLIGNGGTGGAGF
Rv0754|M.tuberculosis_H37Rv         AAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGLIGNGGTGGAGF
MMAR_4953|M.marinum_M               AAHPNGGAGGILFGDGGPGYTPTGGIGAVAGGIGGDAGLIGNGGLGGNGF
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MUL_3507|M.ulcerans_Agy99           -------------------VVNAPAQALLG--------RPLIGDGAAGTA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------PIASGNQVMSPS
                                                                                      

Mb0776|M.bovis_AF2122/97            AGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGA
Rv0754|M.tuberculosis_H37Rv         AGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGA
MMAR_4953|M.marinum_M               GGGTGGMGGTGGWLMGNGGGGGVGGVGG---VGGQALFFGNGGAGGGSAL
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHG--YDGSAAGLAGGNGGNAGLFGNGGNGGVGWA
MUL_3507|M.ulcerans_Agy99           ASPNGGAGGLLYGNGGAGYSYTSGATAEAGGNGGAAGLIGNGGAGGSGWA
MAB_4284c|M.abscessus_ATCC_199      GNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGS
                                                                                      

Mb0776|M.bovis_AF2122/97            GGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLID
Rv0754|M.tuberculosis_H37Rv         GGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLID
MMAR_4953|M.marinum_M               G------GRAGLFIGEPGTGWVADPGNGQSIVIDFVRHGQTASNVAELID
Mflv_4577|M.gilvum_PYR-GCK          ---------------------------SWAMTLTFVRHAESLANEAGIID
TH_4040|M.thermoresistible__bu      ---------------------------AWSMTVTFVRHGESQANAAHIIE
Mvan_5262|M.vanbaalenii_PYR-1       ---------------------------AADIVLTFVRHGQSQANADGIIN
MAV_4778|M.avium_104                ---------------------------DESIVIDLVRHGQSVANAAGLID
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGG
MUL_3507|M.ulcerans_Agy99           GGAGGAGGNGGWLYGNGGAGGLGGAAAG---DYTAGGVGGAGGNAG-LWG
MAB_4284c|M.abscessus_ATCC_199      TAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVT
                                                                                      

Mb0776|M.bovis_AF2122/97            T-AVPGPGLTALGQQQAQAIANALAAKGP----YAGIFDSQLIR------
Rv0754|M.tuberculosis_H37Rv         T-AVPGPGLTALGQQQAQAIANALAAKGP----YAGIFDSQLIR------
MMAR_4953|M.marinum_M               T-NVPGPPLTAEGHLQADIIAGQLFAKGP----YAGIFDSELLR------
Mflv_4577|M.gilvum_PYR-GCK          T-RVPGPGLSEAGELQARAIAPVLAGMG-----FDGIYVSSMLR------
TH_4040|M.thermoresistible__bu      T-DIPGRGLTERGHAEAAAVAEILARNG-----HDKAYSSPLLR------
Mvan_5262|M.vanbaalenii_PYR-1       T-EVPGPHITALGQQQAALVAGVLAAGG-----YQGIYASDMVR------
MAV_4778|M.avium_104                T-AVPGASLTQLGQQQAQTVAGVLAARGP----VAAIFASQLIR------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTV
MUL_3507|M.ulcerans_Agy99           DGGAGGNGSATYDYDQNFSRLGALEGAG-----GNGGHGGLLFG------
MAB_4284c|M.abscessus_ATCC_199      VVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG------
                                                                                      

Mb0776|M.bovis_AF2122/97            --TQQTAAPLANLLGMAPQ-VLPGLN------------------------
Rv0754|M.tuberculosis_H37Rv         --TQQTAAPLANLLGMAPQ-VLPGLN------------------------
MMAR_4953|M.marinum_M               --TQQTAAPLAALYGITDVPALSGLN------------------------
Mflv_4577|M.gilvum_PYR-GCK          --TQLTAQPMLDLLPGSSYQVLPGLR------------------------
TH_4040|M.thermoresistible__bu      --TLETARHFAD--DDSEITRLEGMR------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --TQETAAPLAD-ILGESVTVLPGLR------------------------
MAV_4778|M.avium_104                --TQQTAAPLAS-ALGMNVQVLPGLN------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHA
MUL_3507|M.ulcerans_Agy99           ---NGGGGGDAGANNKFVTAQATPNGAAGG--------------------
MAB_4284c|M.abscessus_ATCC_199      --TSTSAGGSAAVGGNAGLAGNAGLAG-----------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            ------EIHAGIFEDLPQIS-PAGLLYLVGPIAWT---------------
Rv0754|M.tuberculosis_H37Rv         ------EIHAGIFEDLPQIS-PAGLLYLVGPIAWT---------------
MMAR_4953|M.marinum_M               ------EISAGIFDGLQQIT-PAGLLYLIGPMAWT---------------
Mflv_4577|M.gilvum_PYR-GCK          ------EISAGIFEGSSENEGLGRLGYALAPVTWM---------------
TH_4040|M.thermoresistible__bu      ------EIPGGWFEGARDDSGLERLLYGLPGIAWA---------------
Mvan_5262|M.vanbaalenii_PYR-1       ------EIDAGIYEGSSETDGLGRLGYGLTPALWT---------------
MAV_4778|M.avium_104                ------EIDAGIFNGQPQFS-LGGLAYLLAPIAWM---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      IGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHST
MUL_3507|M.ulcerans_Agy99           YGGNAGLWGNG---GAGGDGGFGGTATVIGDG------------------
MAB_4284c|M.abscessus_ATCC_199      ------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAG--------------
                                                                                      

Mb0776|M.bovis_AF2122/97            -LGFPIVPMLAPGST---------------DVNGIVFNRAFTGAVQTIYD
Rv0754|M.tuberculosis_H37Rv         -LGFPIVPMLAPGST---------------DVNGIVFNRAFTGAVQTIYD
MMAR_4953|M.marinum_M               -LGYPIVPMLTPGSL---------------DFNGVVFNQDFTHAMDTMYS
Mflv_4577|M.gilvum_PYR-GCK          -LGAR----FVPVPG---------------GEDGNAFDARVDGAIAEIAD
TH_4040|M.thermoresistible__bu      -LGLR----FIPVLG---------------SEDGNAFDARVDAALRQIHA
Mvan_5262|M.vanbaalenii_PYR-1       -LGLRSA--WIPDST---------------DTNGNVFSDRMSEAVQIIYE
MAV_4778|M.avium_104                -LGLRIVPMLAPGSA---------------DANGYEFRRRFDGALQTVYG
MLBr_01183|M.leprae_Br4923          ----------MPLFL---------------NAEPQALTAAAN-TLEGLSA
MSMEG_0868|M.smegmatis_MC2_155      GTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYS
MUL_3507|M.ulcerans_Agy99           --GTGGNGGLLS-------------------GDGGAGGVGGTGGI-QIYS
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGNAG-------------LAGNAGLAGNAGLAGNAGLAGN
                                                                                      

Mb0776|M.bovis_AF2122/97            ASLAN---------------------------------------------
Rv0754|M.tuberculosis_H37Rv         ASLAN---------------------------------------------
MMAR_4953|M.marinum_M               AALAN---------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          N-------------------------------------------------
TH_4040|M.thermoresistible__bu      DYLA----------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       D-------------------------------------------------
MAV_4778|M.avium_104                SAAASA--------------------------------------------
MLBr_01183|M.leprae_Br4923          A-------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAK
MUL_3507|M.ulcerans_Agy99           G-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAG---------------------------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            -------------------------------PVVAADGNITSVAYS----
Rv0754|M.tuberculosis_H37Rv         -------------------------------PVVAADGNITSVAYS----
MMAR_4953|M.marinum_M               -------------------------------PVLAANGKITDVAYS----
Mflv_4577|M.gilvum_PYR-GCK          -------------------------------------GDENAVAFA----
TH_4040|M.thermoresistible__bu      ------------------------------------GETQNPVVFG----
Mvan_5262|M.vanbaalenii_PYR-1       -------------------------------------GWARPVAFS----
MAV_4778|M.avium_104                --------------GGFGDVLQAVYAGAVTNPVRAANGRITGVAFS----
MLBr_01183|M.leprae_Br4923          -----------------------------------------TVASN----
MSMEG_0868|M.smegmatis_MC2_155      AGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVG
MUL_3507|M.ulcerans_Agy99           ---------GGIGGVGG------------------IGGNGGAGGTSGLIG
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------NAGLAGNAGLAG---
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPA
MUL_3507|M.ulcerans_Agy99           --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            ------------------SAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAV
Rv0754|M.tuberculosis_H37Rv         ------------------SAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAV
MMAR_4953|M.marinum_M               ------------------SAFTIGVGTMMNVDNPDPLLLLTHPLPNTGVV
Mflv_4577|M.gilvum_PYR-GCK          ------------------HGATIMFWVMMNVDNPDLLLMLRHQLDNVESV
TH_4040|M.thermoresistible__bu      ------------------HGGTIMFWTMMNVDNPDLLLMLTHTLGNTETV
Mvan_5262|M.vanbaalenii_PYR-1       ------------------HGATIMFWTMMNVDNPDLGLLLSHQLPNTGVV
MAV_4778|M.avium_104                ------------------SEFAIGVGTMMTVKNPDPLVLLFDPLPNTGIV
MLBr_01183|M.leprae_Br4923          ------------------AAAAQLTTEIAPPAADDVSILLAHFFS-----
MSMEG_0868|M.smegmatis_MC2_155      GTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQT
MUL_3507|M.ulcerans_Agy99           ------------DGGAGGAGGTGGGNAGVGG-------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA
                                                                                      

Mb0776|M.bovis_AF2122/97            VVQGNPEGGWTLVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWE
Rv0754|M.tuberculosis_H37Rv         VVQGNPEGGWTLVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWE
MMAR_4953|M.marinum_M               EVQGSPANGWTMVSWDGIPVAP-ATLPTQLFVDVRNLITAPQYAGWDIFY
Mflv_4577|M.gilvum_PYR-GCK          VVEGSPEEGWTLVSWAGQAVSADPSLATKLLVNVRDLVVAPQTALYNVGT
TH_4040|M.thermoresistible__bu      VIEGSPDEGWTLVSWAGVEVSRTPSLPTTLFVRTRDLLVAPQTALYNLGQ
Mvan_5262|M.vanbaalenii_PYR-1       VLEGNPEDGWTLVSWDGVAVDPDPSFLTKTFVNVRELITTPQTAVYNVKK
MAV_4778|M.avium_104                VIQGSPRDGWTLISWNGKPVHPGWSATRNGRGANGLCLMLDPSTRTGVCA
MLBr_01183|M.leprae_Br4923          ---G---HGRQYQAHASQGATNHQDLIQSLLTSS---------SAY----
MSMEG_0868|M.smegmatis_MC2_155      DTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGG
MUL_3507|M.ulcerans_Agy99           -VGGVGGTGGAARLFGSGGSGGIGGTGGHSLINSG-GGIGGKGGGGGAAG
MAB_4284c|M.abscessus_ATCC_199      AVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSG
                                       *    .       .                                 

Mb0776|M.bovis_AF2122/97            -------------SLFTGDPAAVINAVRDGADEVGAAVVQ----------
Rv0754|M.tuberculosis_H37Rv         -------------SLFTGDPAAVINAVRDGADEVGAAVVQ----------
MMAR_4953|M.marinum_M               -------------SLFTGNPTTILTAVRDGIEEVGSAVIN----------
Mflv_4577|M.gilvum_PYR-GCK          -------------AFSSGDFETLVNAVRDGLIEVTRAVVRFIPDTVRDIV
TH_4040|M.thermoresistible__bu      -------------ALRTGDVVTVVEALRDGILDVVX--------------
Mvan_5262|M.vanbaalenii_PYR-1       -------------AFATGDLAAITDSFAQAVIDVVLAPVR----------
MAV_4778|M.avium_104                -------------AKPPGPASAPVAARPGLS-------------------
MLBr_01183|M.leprae_Br4923          ----------------AGTETANHDSL-----------------------
MSMEG_0868|M.smegmatis_MC2_155      DGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGA
MUL_3507|M.ulcerans_Agy99           -------------LIGDGGAGGAGGNGGDG--------TGAGGLGGNG--
MAB_4284c|M.abscessus_ATCC_199      ---------------SVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGIS
                                                     *                                

Mb0776|M.bovis_AF2122/97            --FPHAVADDVIDATGHPYLSGLPIGLPSLIP------------------
Rv0754|M.tuberculosis_H37Rv         --FPHAVADDVIDATGHPYLSGLPIGLPSLIP------------------
MMAR_4953|M.marinum_M               --FPIEVTEDVVNAICG-ATDGLTAGAPSLVG------------------
Mflv_4577|M.gilvum_PYR-GCK          DEFRPSVTEDSLDVTELHRAVVTAAPQDDDEAEPQSVAVAEAETRNGSGV
TH_4040|M.thermoresistible__bu      ---XPGTSPTMMRAATHRR-------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --FVGAVATDVLELVFPPAPSVQVEAPMSAESTTDESDVPADVPDDVVAV
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGS
MUL_3507|M.ulcerans_Agy99           -------ASADWIGNGGSGGAGGSGGLGAHAG------------------
MAB_4284c|M.abscessus_ATCC_199      ESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          APAGSTPPSGDEVTGSTDDDEATASDVVLEDTVDVDTIDVDTVEEDTGAS
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       APS--------EDVESRTPEPASDEAETREESAAPESEATEPEISASQSE
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHG
MUL_3507|M.ulcerans_Agy99           ---------AGGNGGSLYGNDGSGGAG--------------------GTG
MAB_4284c|M.abscessus_ATCC_199      ----VGSHVGGGISESLGGSGSVGGSTAVG-----------------GGA
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          DHAVGN--------HPDAEADDAAPANGSAKSSDDDGDSDDDASERAAA-
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       ESEVET--------ETTEETTTAG-----TTGDDDTDETDDGAAVKEAA-
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDG
MUL_3507|M.ulcerans_Agy99           ASG---------------------------AGGNGGGGGAAGMMGDGG--
MAB_4284c|M.abscessus_ATCC_199      HTGVGGG-----------------VNTGVGVGSHVGGGISESLGGSGSVG
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLG
MUL_3507|M.ulcerans_Agy99           ------------------AGGDGG--------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGA
MUL_3507|M.ulcerans_Agy99           ---DGSAAGGLGGDGGNADWLGNGG-------------------GGTGGF
MAB_4284c|M.abscessus_ATCC_199      ---GSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSI
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQ
MUL_3507|M.ulcerans_Agy99           GLPP-ATGGFG-------------------GRGGRLFGSPGAQGRR----
MAB_4284c|M.abscessus_ATCC_199      NASHSSS---------------------MNESFGSSMGSHGAAGTGFEAQ
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSG
MUL_3507|M.ulcerans_Agy99           ---------ALMCLSAACRC------------------------------
MAB_4284c|M.abscessus_ATCC_199      GHAQGHASETAHTTLPGAEHH-----------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4953|M.marinum_M               --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4040|M.thermoresistible__bu      --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4778|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNG
MUL_3507|M.ulcerans_Agy99           --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0776|M.bovis_AF2122/97            --------------------------
Rv0754|M.tuberculosis_H37Rv         --------------------------
MMAR_4953|M.marinum_M               --------------------------
Mflv_4577|M.gilvum_PYR-GCK          --------------------------
TH_4040|M.thermoresistible__bu      --------------------------
Mvan_5262|M.vanbaalenii_PYR-1       --------------------------
MAV_4778|M.avium_104                --------------------------
MLBr_01183|M.leprae_Br4923          --------------------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGADGTPGTAGTTGANNP
MUL_3507|M.ulcerans_Agy99           --------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------