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SFVLVAPDMLATAAADVVQIGSAVSAGNLAAAIPTTEVMAAAADEVSGAIAALFGANAQEYQAAAAQAAT FHEQFVRALSEAGASYASAEATIVTGLSSAVADGFQTAVYGPIRAAGQAWISSPAGEVVDPVINAPTEAL FGRGLISNGAAGTAAHPNGGAGGILFGDGGPGYTPTGGIGAVAGGIGGDAGLIGNGGLGGNGFGGGTGGM GGTGGWLMGNGGGGGVGGVGGVGGQALFFGNGGAGGGSALGGRAGLFIGEPGTGWVADPGNGQSIVIDFV RHGQTASNVAELIDTNVPGPPLTAEGHLQADIIAGQLFAKGPYAGIFDSELLRTQQTAAPLAALYGITDV PALSGLNEISAGIFDGLQQITPAGLLYLIGPMAWTLGYPIVPMLTPGSLDFNGVVFNQDFTHAMDTMYSA ALANPVLAANGKITDVAYSSAFTIGVGTMMNVDNPDPLLLLTHPLPNTGVVEVQGSPANGWTMVSWDGIP VAPATLPTQLFVDVRNLITAPQYAGWDIFYSLFTGNPTTILTAVRDGIEEVGSAVINFPIEVTEDVVNAI CGATDGLTAGAPSLVG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4953 | - | - | 100% (577) | PE-PGRS family protein |
M. marinum M | MMAR_3570 | - | 1e-66 | 50.51% (295) | PE-PGRS family protein |
M. marinum M | MMAR_3199 | - | 3e-66 | 49.65% (284) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0776 | PE_PGRS11 | 0.0 | 66.95% (593) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_4577 | - | 4e-49 | 42.16% (287) | phosphoglycerate mutase |
M. tuberculosis H37Rv | Rv0754 | PE_PGRS11 | 0.0 | 66.95% (593) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 6e-11 | 37.08% (89) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-12 | 37.68% (138) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4778 | - | 2e-68 | 55.51% (245) | pe_pgrs family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-36 | 48.63% (183) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4040 | - | 2e-42 | 39.42% (274) | PUTATIVE Phosphoglycerate mutase |
M. ulcerans Agy99 | MUL_3507 | - | 5e-66 | 48.01% (302) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_5262 | - | 6e-54 | 42.33% (300) | phosphoglycerate mutase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0776|M.bovis_AF2122/97 ------------MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTA Rv0754|M.tuberculosis_H37Rv ------------MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTA MMAR_4953|M.marinum_M ------------MSFVLVAPDMLATAAADVVQIGSAVSAGNLAAAIPTTE Mflv_4577|M.gilvum_PYR-GCK ----------------------------------------MPDPR--TCR TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 ----------------------------------------MRDVRRTARR MAV_4778|M.avium_104 -------------------------------------------MLRTPLC MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES MUL_3507|M.ulcerans_Agy99 ------------MSFVSVTQEALAAAASDVGVIGSSLQAANMSVAAPTAG MAB_4284c|M.abscessus_ATCC_199 ---------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQV Mb0776|M.bovis_AF2122/97 VA---------------------------AAAADEVSAALAALFGAHARE Rv0754|M.tuberculosis_H37Rv VA---------------------------AAAADEVSAALAALFGAHARE MMAR_4953|M.marinum_M VM---------------------------AAAADEVSGAIAALFGANAQE Mflv_4577|M.gilvum_PYR-GCK VR---------------------------RILIAALSAVLLVLVSAIP-- TH_4040|M.thermoresistible__bu ------------------------------VVVAAISAALLFIVSAIP-- Mvan_5262|M.vanbaalenii_PYR-1 LL---------------------------TILAATLAAAVLFAASAFA-- MAV_4778|M.avium_104 RA---------------------------GAVLASVVLLCSASATASA-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT MUL_3507|M.ulcerans_Agy99 VL---------------------------AAGADEVSVAMAALFSGHGQA MAB_4284c|M.abscessus_ATCC_199 GAVMP-----------------------VVAESVASNYGYQSQWVNTGNP Mb0776|M.bovis_AF2122/97 YQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSD Rv0754|M.tuberculosis_H37Rv YQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSD MMAR_4953|M.marinum_M YQAAAAQAATFHEQFVRALSEAGASYASAEATIVTGLS-------SAVAD Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA MUL_3507|M.ulcerans_Agy99 YQTLSAQANAFHAQFLQALTNAGG-----------------------AYA MAB_4284c|M.abscessus_ATCC_199 IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN------------DFLSHN Mb0776|M.bovis_AF2122/97 GFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGT Rv0754|M.tuberculosis_H37Rv GFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGT MMAR_4953|M.marinum_M GFQTAVYGPIRAAGQAWISSPAGEVVDPVINAPTEALFGRGLISNGAAGT Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP MUL_3507|M.ulcerans_Agy99 AAEVANLS------------------------------PLQGVEQGVLG- MAB_4284c|M.abscessus_ATCC_199 DTDFASHN------------------------------------------ Mb0776|M.bovis_AF2122/97 AAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGLIGNGGTGGAGF Rv0754|M.tuberculosis_H37Rv AAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGLIGNGGTGGAGF MMAR_4953|M.marinum_M AAHPNGGAGGILFGDGGPGYTPTGGIGAVAGGIGGDAGLIGNGGLGGNGF Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA MUL_3507|M.ulcerans_Agy99 -------------------VVNAPAQALLG--------RPLIGDGAAGTA MAB_4284c|M.abscessus_ATCC_199 --------------------------------------PIASGNQVMSPS Mb0776|M.bovis_AF2122/97 AGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGA Rv0754|M.tuberculosis_H37Rv AGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGA MMAR_4953|M.marinum_M GGGTGGMGGTGGWLMGNGGGGGVGGVGG---VGGQALFFGNGGAGGGSAL Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHG--YDGSAAGLAGGNGGNAGLFGNGGNGGVGWA MUL_3507|M.ulcerans_Agy99 ASPNGGAGGLLYGNGGAGYSYTSGATAEAGGNGGAAGLIGNGGAGGSGWA MAB_4284c|M.abscessus_ATCC_199 GNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGS Mb0776|M.bovis_AF2122/97 GGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLID Rv0754|M.tuberculosis_H37Rv GGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLID MMAR_4953|M.marinum_M G------GRAGLFIGEPGTGWVADPGNGQSIVIDFVRHGQTASNVAELID Mflv_4577|M.gilvum_PYR-GCK ---------------------------SWAMTLTFVRHAESLANEAGIID TH_4040|M.thermoresistible__bu ---------------------------AWSMTVTFVRHGESQANAAHIIE Mvan_5262|M.vanbaalenii_PYR-1 ---------------------------AADIVLTFVRHGQSQANADGIIN MAV_4778|M.avium_104 ---------------------------DESIVIDLVRHGQSVANAAGLID MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGG MUL_3507|M.ulcerans_Agy99 GGAGGAGGNGGWLYGNGGAGGLGGAAAG---DYTAGGVGGAGGNAG-LWG MAB_4284c|M.abscessus_ATCC_199 TAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVT Mb0776|M.bovis_AF2122/97 T-AVPGPGLTALGQQQAQAIANALAAKGP----YAGIFDSQLIR------ Rv0754|M.tuberculosis_H37Rv T-AVPGPGLTALGQQQAQAIANALAAKGP----YAGIFDSQLIR------ MMAR_4953|M.marinum_M T-NVPGPPLTAEGHLQADIIAGQLFAKGP----YAGIFDSELLR------ Mflv_4577|M.gilvum_PYR-GCK T-RVPGPGLSEAGELQARAIAPVLAGMG-----FDGIYVSSMLR------ TH_4040|M.thermoresistible__bu T-DIPGRGLTERGHAEAAAVAEILARNG-----HDKAYSSPLLR------ Mvan_5262|M.vanbaalenii_PYR-1 T-EVPGPHITALGQQQAALVAGVLAAGG-----YQGIYASDMVR------ MAV_4778|M.avium_104 T-AVPGASLTQLGQQQAQTVAGVLAARGP----VAAIFASQLIR------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTV MUL_3507|M.ulcerans_Agy99 DGGAGGNGSATYDYDQNFSRLGALEGAG-----GNGGHGGLLFG------ MAB_4284c|M.abscessus_ATCC_199 VVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG------ Mb0776|M.bovis_AF2122/97 --TQQTAAPLANLLGMAPQ-VLPGLN------------------------ Rv0754|M.tuberculosis_H37Rv --TQQTAAPLANLLGMAPQ-VLPGLN------------------------ MMAR_4953|M.marinum_M --TQQTAAPLAALYGITDVPALSGLN------------------------ Mflv_4577|M.gilvum_PYR-GCK --TQLTAQPMLDLLPGSSYQVLPGLR------------------------ TH_4040|M.thermoresistible__bu --TLETARHFAD--DDSEITRLEGMR------------------------ Mvan_5262|M.vanbaalenii_PYR-1 --TQETAAPLAD-ILGESVTVLPGLR------------------------ MAV_4778|M.avium_104 --TQQTAAPLAS-ALGMNVQVLPGLN------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHA MUL_3507|M.ulcerans_Agy99 ---NGGGGGDAGANNKFVTAQATPNGAAGG-------------------- MAB_4284c|M.abscessus_ATCC_199 --TSTSAGGSAAVGGNAGLAGNAGLAG----------------------- Mb0776|M.bovis_AF2122/97 ------EIHAGIFEDLPQIS-PAGLLYLVGPIAWT--------------- Rv0754|M.tuberculosis_H37Rv ------EIHAGIFEDLPQIS-PAGLLYLVGPIAWT--------------- MMAR_4953|M.marinum_M ------EISAGIFDGLQQIT-PAGLLYLIGPMAWT--------------- Mflv_4577|M.gilvum_PYR-GCK ------EISAGIFEGSSENEGLGRLGYALAPVTWM--------------- TH_4040|M.thermoresistible__bu ------EIPGGWFEGARDDSGLERLLYGLPGIAWA--------------- Mvan_5262|M.vanbaalenii_PYR-1 ------EIDAGIYEGSSETDGLGRLGYGLTPALWT--------------- MAV_4778|M.avium_104 ------EIDAGIFNGQPQFS-LGGLAYLLAPIAWM--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 IGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHST MUL_3507|M.ulcerans_Agy99 YGGNAGLWGNG---GAGGDGGFGGTATVIGDG------------------ MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAG-------------- Mb0776|M.bovis_AF2122/97 -LGFPIVPMLAPGST---------------DVNGIVFNRAFTGAVQTIYD Rv0754|M.tuberculosis_H37Rv -LGFPIVPMLAPGST---------------DVNGIVFNRAFTGAVQTIYD MMAR_4953|M.marinum_M -LGYPIVPMLTPGSL---------------DFNGVVFNQDFTHAMDTMYS Mflv_4577|M.gilvum_PYR-GCK -LGAR----FVPVPG---------------GEDGNAFDARVDGAIAEIAD TH_4040|M.thermoresistible__bu -LGLR----FIPVLG---------------SEDGNAFDARVDAALRQIHA Mvan_5262|M.vanbaalenii_PYR-1 -LGLRSA--WIPDST---------------DTNGNVFSDRMSEAVQIIYE MAV_4778|M.avium_104 -LGLRIVPMLAPGSA---------------DANGYEFRRRFDGALQTVYG MLBr_01183|M.leprae_Br4923 ----------MPLFL---------------NAEPQALTAAAN-TLEGLSA MSMEG_0868|M.smegmatis_MC2_155 GTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYS MUL_3507|M.ulcerans_Agy99 --GTGGNGGLLS-------------------GDGGAGGVGGTGGI-QIYS MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAG-------------LAGNAGLAGNAGLAGNAGLAGN Mb0776|M.bovis_AF2122/97 ASLAN--------------------------------------------- Rv0754|M.tuberculosis_H37Rv ASLAN--------------------------------------------- MMAR_4953|M.marinum_M AALAN--------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK N------------------------------------------------- TH_4040|M.thermoresistible__bu DYLA---------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 D------------------------------------------------- MAV_4778|M.avium_104 SAAASA-------------------------------------------- MLBr_01183|M.leprae_Br4923 A------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAK MUL_3507|M.ulcerans_Agy99 G------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAG--------------------------------------------- Mb0776|M.bovis_AF2122/97 -------------------------------PVVAADGNITSVAYS---- Rv0754|M.tuberculosis_H37Rv -------------------------------PVVAADGNITSVAYS---- MMAR_4953|M.marinum_M -------------------------------PVLAANGKITDVAYS---- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------GDENAVAFA---- TH_4040|M.thermoresistible__bu ------------------------------------GETQNPVVFG---- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------GWARPVAFS---- MAV_4778|M.avium_104 --------------GGFGDVLQAVYAGAVTNPVRAANGRITGVAFS---- MLBr_01183|M.leprae_Br4923 -----------------------------------------TVASN---- MSMEG_0868|M.smegmatis_MC2_155 AGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVG MUL_3507|M.ulcerans_Agy99 ---------GGIGGVGG------------------IGGNGGAGGTSGLIG MAB_4284c|M.abscessus_ATCC_199 -----------------------------------NAGLAGNAGLAG--- Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPA MUL_3507|M.ulcerans_Agy99 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0776|M.bovis_AF2122/97 ------------------SAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAV Rv0754|M.tuberculosis_H37Rv ------------------SAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAV MMAR_4953|M.marinum_M ------------------SAFTIGVGTMMNVDNPDPLLLLTHPLPNTGVV Mflv_4577|M.gilvum_PYR-GCK ------------------HGATIMFWVMMNVDNPDLLLMLRHQLDNVESV TH_4040|M.thermoresistible__bu ------------------HGGTIMFWTMMNVDNPDLLLMLTHTLGNTETV Mvan_5262|M.vanbaalenii_PYR-1 ------------------HGATIMFWTMMNVDNPDLGLLLSHQLPNTGVV MAV_4778|M.avium_104 ------------------SEFAIGVGTMMTVKNPDPLVLLFDPLPNTGIV MLBr_01183|M.leprae_Br4923 ------------------AAAAQLTTEIAPPAADDVSILLAHFFS----- MSMEG_0868|M.smegmatis_MC2_155 GTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQT MUL_3507|M.ulcerans_Agy99 ------------DGGAGGAGGTGGGNAGVGG------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA Mb0776|M.bovis_AF2122/97 VVQGNPEGGWTLVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWE Rv0754|M.tuberculosis_H37Rv VVQGNPEGGWTLVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWE MMAR_4953|M.marinum_M EVQGSPANGWTMVSWDGIPVAP-ATLPTQLFVDVRNLITAPQYAGWDIFY Mflv_4577|M.gilvum_PYR-GCK VVEGSPEEGWTLVSWAGQAVSADPSLATKLLVNVRDLVVAPQTALYNVGT TH_4040|M.thermoresistible__bu VIEGSPDEGWTLVSWAGVEVSRTPSLPTTLFVRTRDLLVAPQTALYNLGQ Mvan_5262|M.vanbaalenii_PYR-1 VLEGNPEDGWTLVSWDGVAVDPDPSFLTKTFVNVRELITTPQTAVYNVKK MAV_4778|M.avium_104 VIQGSPRDGWTLISWNGKPVHPGWSATRNGRGANGLCLMLDPSTRTGVCA MLBr_01183|M.leprae_Br4923 ---G---HGRQYQAHASQGATNHQDLIQSLLTSS---------SAY---- MSMEG_0868|M.smegmatis_MC2_155 DTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGG MUL_3507|M.ulcerans_Agy99 -VGGVGGTGGAARLFGSGGSGGIGGTGGHSLINSG-GGIGGKGGGGGAAG MAB_4284c|M.abscessus_ATCC_199 AVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSG * . . Mb0776|M.bovis_AF2122/97 -------------SLFTGDPAAVINAVRDGADEVGAAVVQ---------- Rv0754|M.tuberculosis_H37Rv -------------SLFTGDPAAVINAVRDGADEVGAAVVQ---------- MMAR_4953|M.marinum_M -------------SLFTGNPTTILTAVRDGIEEVGSAVIN---------- Mflv_4577|M.gilvum_PYR-GCK -------------AFSSGDFETLVNAVRDGLIEVTRAVVRFIPDTVRDIV TH_4040|M.thermoresistible__bu -------------ALRTGDVVTVVEALRDGILDVVX-------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------AFATGDLAAITDSFAQAVIDVVLAPVR---------- MAV_4778|M.avium_104 -------------AKPPGPASAPVAARPGLS------------------- MLBr_01183|M.leprae_Br4923 ----------------AGTETANHDSL----------------------- MSMEG_0868|M.smegmatis_MC2_155 DGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGA MUL_3507|M.ulcerans_Agy99 -------------LIGDGGAGGAGGNGGDG--------TGAGGLGGNG-- MAB_4284c|M.abscessus_ATCC_199 ---------------SVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGIS * Mb0776|M.bovis_AF2122/97 --FPHAVADDVIDATGHPYLSGLPIGLPSLIP------------------ Rv0754|M.tuberculosis_H37Rv --FPHAVADDVIDATGHPYLSGLPIGLPSLIP------------------ MMAR_4953|M.marinum_M --FPIEVTEDVVNAICG-ATDGLTAGAPSLVG------------------ Mflv_4577|M.gilvum_PYR-GCK DEFRPSVTEDSLDVTELHRAVVTAAPQDDDEAEPQSVAVAEAETRNGSGV TH_4040|M.thermoresistible__bu ---XPGTSPTMMRAATHRR------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 --FVGAVATDVLELVFPPAPSVQVEAPMSAESTTDESDVPADVPDDVVAV MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGS MUL_3507|M.ulcerans_Agy99 -------ASADWIGNGGSGGAGGSGGLGAHAG------------------ MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG------------------ Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK APAGSTPPSGDEVTGSTDDDEATASDVVLEDTVDVDTIDVDTVEEDTGAS TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 APS--------EDVESRTPEPASDEAETREESAAPESEATEPEISASQSE MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHG MUL_3507|M.ulcerans_Agy99 ---------AGGNGGSLYGNDGSGGAG--------------------GTG MAB_4284c|M.abscessus_ATCC_199 ----VGSHVGGGISESLGGSGSVGGSTAVG-----------------GGA Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK DHAVGN--------HPDAEADDAAPANGSAKSSDDDGDSDDDASERAAA- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 ESEVET--------ETTEETTTAG-----TTGDDDTDETDDGAAVKEAA- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDG MUL_3507|M.ulcerans_Agy99 ASG---------------------------AGGNGGGGGAAGMMGDGG-- MAB_4284c|M.abscessus_ATCC_199 HTGVGGG-----------------VNTGVGVGSHVGGGISESLGGSGSVG Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 VVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLG MUL_3507|M.ulcerans_Agy99 ------------------AGGDGG-------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGA MUL_3507|M.ulcerans_Agy99 ---DGSAAGGLGGDGGNADWLGNGG-------------------GGTGGF MAB_4284c|M.abscessus_ATCC_199 ---GSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSI Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQ MUL_3507|M.ulcerans_Agy99 GLPP-ATGGFG-------------------GRGGRLFGSPGAQGRR---- MAB_4284c|M.abscessus_ATCC_199 NASHSSS---------------------MNESFGSSMGSHGAAGTGFEAQ Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSG MUL_3507|M.ulcerans_Agy99 ---------ALMCLSAACRC------------------------------ MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH----------------------------- Mb0776|M.bovis_AF2122/97 -------------------------------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4953|M.marinum_M -------------------------------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------------------------------- TH_4040|M.thermoresistible__bu -------------------------------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_4778|M.avium_104 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNG MUL_3507|M.ulcerans_Agy99 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0776|M.bovis_AF2122/97 -------------------------- Rv0754|M.tuberculosis_H37Rv -------------------------- MMAR_4953|M.marinum_M -------------------------- Mflv_4577|M.gilvum_PYR-GCK -------------------------- TH_4040|M.thermoresistible__bu -------------------------- Mvan_5262|M.vanbaalenii_PYR-1 -------------------------- MAV_4778|M.avium_104 -------------------------- MLBr_01183|M.leprae_Br4923 -------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGADGTPGTAGTTGANNP MUL_3507|M.ulcerans_Agy99 -------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------