For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4040 | - | - | 100% (296) | Phosphoglycerate mutase |
| M. thermoresistible (build 8) | TH_2144 | - | 4e-42 | 45.97% (211) | phosphoglycerate mutase family protein |
| M. thermoresistible (build 8) | TH_1473 | - | 1e-12 | 28.36% (201) | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0776 | PE_PGRS11 | 2e-44 | 42.49% (273) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_4577 | - | 1e-84 | 57.71% (279) | phosphoglycerate mutase |
| M. tuberculosis H37Rv | Rv0754 | PE_PGRS11 | 2e-44 | 42.49% (273) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_00079 | - | 2e-10 | 26.98% (215) | putative phosphoglycerate mutase |
| M. abscessus ATCC 19977 | MAB_0133 | - | 1e-08 | 26.67% (210) | phosphoglycerate mutase |
| M. marinum M | MMAR_4953 | - | 2e-42 | 39.42% (274) | PE-PGRS family protein |
| M. avium 104 | MAV_4339 | - | 3e-35 | 39.62% (212) | phosphoglycerate mutase family protein |
| M. smegmatis MC2 155 | MSMEG_6545 | - | 3e-40 | 42.04% (226) | phosphoglycerate mutase family protein |
| M. ulcerans Agy99 | MUL_0919 | lpqD | 5e-32 | 37.68% (207) | lipoprotein, LpqD |
| M. vanbaalenii PYR-1 | Mvan_5262 | - | 7e-69 | 47.89% (284) | phosphoglycerate mutase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0776|M.bovis_AF2122/97 MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAA
Rv0754|M.tuberculosis_H37Rv MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAA
MMAR_4953|M.marinum_M MSFVLVAPDMLATAAADVVQIGSAVSAGNLAAAIPTTEVMAAAADEVSGA
TH_4040|M.thermoresistible__bu -------------------VVVAAISAALLFIVS----------------
Mflv_4577|M.gilvum_PYR-GCK ------MPDPR--TCRVRRILIAALSAVLLVLVS----------------
Mvan_5262|M.vanbaalenii_PYR-1 ------MRDVRRTARRLLTILAATLAAAVLFAAS----------------
MSMEG_6545|M.smegmatis_MC2_155 -------MTTHTRRTAAVAALVVALVAGMLTAPN----------------
MAV_4339|M.avium_104 ---------------MALAALIATVTVAACGG------------------
MUL_0919|M.ulcerans_Agy99 ----MAKRSMIWNTSKVLALLATAMLPGACGGG-----------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 LAALFGAHAREYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRG
Rv0754|M.tuberculosis_H37Rv LAALFGAHAREYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRG
MMAR_4953|M.marinum_M IAALFGANAQEYQAAAAQAATFHEQFVRALSEAGASYASAEATIVTGLS-
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 ALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLG
Rv0754|M.tuberculosis_H37Rv ALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLG
MMAR_4953|M.marinum_M ------SAVADGFQTAVYGPIRAAGQAWISSPAGEVVDPVINAPTEALFG
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 RDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGL
Rv0754|M.tuberculosis_H37Rv RDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYT---------GGNGGSAGL
MMAR_4953|M.marinum_M RGLISNGAAGTAAHPNGGAGGILFGDGGPGYTPTGGIGAVAGGIGGDAGL
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 IGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLF
Rv0754|M.tuberculosis_H37Rv IGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLF
MMAR_4953|M.marinum_M IGNGGLGGNGFGGGTGGMGGTGGWLMGNGGGGGVGGVGG---VGGQALFF
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5262|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 GNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHG
Rv0754|M.tuberculosis_H37Rv GNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHG
MMAR_4953|M.marinum_M GNGGAGGGSALG------GRAGLFIGEPGTGWVADPGNGQSIVIDFVRHG
TH_4040|M.thermoresistible__bu -----------------------------------AIPAWSMTVTFVRHG
Mflv_4577|M.gilvum_PYR-GCK -----------------------------------AIPSWAMTLTFVRHA
Mvan_5262|M.vanbaalenii_PYR-1 -----------------------------------AFAAADIVLTFVRHG
MSMEG_6545|M.smegmatis_MC2_155 -----------------------------------AVAQRIITLTLVRHA
MAV_4339|M.avium_104 -----------------------------------SPQARSITVTFVRHA
MUL_0919|M.ulcerans_Agy99 -----------------------------------SPQARSITLTFIRNA
MLBr_00079|M.leprae_Br4923 ---------------------------------------MSSRLVLLRHG
MAB_0133|M.abscessus_ATCC_1997 ----------------------------MARRDAGREAAMSGRLVLVRHG
: ::*:.
Mb0776|M.bovis_AF2122/97 QTPGNAAMLIDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIR
Rv0754|M.tuberculosis_H37Rv QTPGNAAMLIDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIR
MMAR_4953|M.marinum_M QTASNVAELIDTNVPGPPLTAEGHLQADIIAGQLFAKGPYAGIFDSELLR
TH_4040|M.thermoresistible__bu ESQANAAHIIETDIPGRGLTERGHAEAAAVAEILARNG-HDKAYSSPLLR
Mflv_4577|M.gilvum_PYR-GCK ESLANEAGIIDTRVPGPGLSEAGELQARAIAPVLAGMG-FDGIYVSSMLR
Mvan_5262|M.vanbaalenii_PYR-1 QSQANADGIINTEVPGPHITALGQQQAALVAGVLAAGG-YQGIYASDMVR
MSMEG_6545|M.smegmatis_MC2_155 QSEGNASGLIDTSTPGPPLTALGREQAETAAQKLAAGHTFDGIYASTMIR
MAV_4339|M.avium_104 QSEANASGTIDTEVPGPGLSPEGKGQAEQVAHQLGRKD-YDSVYASTMTR
MUL_0919|M.ulcerans_Agy99 QSQADAEGIIATELPGTGLSSDGKDQAQQLTHQFGRSE-FDSIYTSPMEA
MLBr_00079|M.leprae_Br4923 QSYGNVEGRLDTRPPGASLTPFGRDQARVFAQ---AAGRPVLLVHSVAIR
MAB_0133|M.abscessus_ATCC_1997 QSYGNVERRLDTKPPGAALTELGLQQARLFAKRY-EEHAPAVLVHSVAVR
:: .: : * ** :: * :* : *
Mb0776|M.bovis_AF2122/97 TQQTAAPLANLLGMAPQ-VLPGLNEIHAGIFEDLPQ-ISPAGLLYLVGPI
Rv0754|M.tuberculosis_H37Rv TQQTAAPLANLLGMAPQ-VLPGLNEIHAGIFEDLPQ-ISPAGLLYLVGPI
MMAR_4953|M.marinum_M TQQTAAPLAALYGITDVPALSGLNEISAGIFDGLQQ-ITPAGLLYLIGPM
TH_4040|M.thermoresistible__bu TLETARHFAD--DDSEITRLEGMREIPGGWFEGARDDSGLERLLYGLPGI
Mflv_4577|M.gilvum_PYR-GCK TQLTAQPMLDLLPGSSYQVLPGLREISAGIFEGSSENEGLGRLGYALAPV
Mvan_5262|M.vanbaalenii_PYR-1 TQETAAPLAD-ILGESVTVLPGLREIDAGIYEGSSETDGLGRLGYGLTPA
MSMEG_6545|M.smegmatis_MC2_155 TQQTAQPLAD-LSREPVTVLPGLREIEAGIYEGQPE--ALAGFTYYEAPT
MAV_4339|M.avium_104 AQQTAAPLAA-ELGKQVEVLPGIQEINAGWYNGKPE--SMAKSTYLVAPA
MUL_0919|M.ulcerans_Agy99 AQQTAAPLAR-QLSKQAEIVPGLQSIDAGWYNGKPD--SMADRTYMVAPV
MLBr_00079|M.leprae_Br4923 ALETAAVLGA-EFDVPIREIAGIHEVQVGELENRND--DDAIAEFNAIYD
MAB_0133|M.abscessus_ATCC_1997 AVQTAAGIAE-HLGVQAEQIEGLHEVQAGELEDRTD--LEAFAVFDRTYE
: ** : : *:..: * :. : :
Mb0776|M.bovis_AF2122/97 AWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGN
Rv0754|M.tuberculosis_H37Rv AWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGN
MMAR_4953|M.marinum_M AWTLGYPIVPMLTPGSLDFNGVVFNQDFTHAMDTMYSAALANPVLAANGK
TH_4040|M.thermoresistible__bu AWALGLR--FIPVLGSEDGN--AFDARVDAALRQIHADYLA------GET
Mflv_4577|M.gilvum_PYR-GCK TWMLGAR--FVPVPGGEDGN--AFDARVDGAIAEIADN----------GD
Mvan_5262|M.vanbaalenii_PYR-1 LWTLGLRSAWIPDSTDTNGN--VFSDRMSEAVQIIYED----------GW
MSMEG_6545|M.smegmatis_MC2_155 RWLQGDR--TARIPGSIDGD--EFDARFDEAVREIYDS----------ED
MAV_4339|M.avium_104 NWLKGDV--SDSIPGSISGK--EFNDQFTAAVNKIYNS----------GH
MUL_0919|M.ulcerans_Agy99 SWIDGNV--EASIPGSTSGS--DFNSRFTGAIRKIYDG----------GH
MLBr_00079|M.leprae_Br4923 RWHHGELDVPLPGGETANDVLDRYLPVLVDLRMRYLDD---------GDW
MAB_0133|M.abscessus_ATCC_1997 RWHFGDLDARMPGGESAQDVFDRYLPAVADLRLRHLEN---------DAS
* * . : .
Mb0776|M.bovis_AF2122/97 ITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGNPEGGWT
Rv0754|M.tuberculosis_H37Rv ITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGNPEGGWT
MMAR_4953|M.marinum_M ITDVAYSSAFTIGVGTMMNVDNPDPLLLLTHPLPNTGVVEVQGSPANGWT
TH_4040|M.thermoresistible__bu QNPVVFGHGGTIMFWTMMNVDNPDLLLMLTHTLGNTETVVIEGSPDEGWT
Mflv_4577|M.gilvum_PYR-GCK ENAVAFAHGATIMFWVMMNVDNPDLLLMLRHQLDNVESVVVEGSPEEGWT
Mvan_5262|M.vanbaalenii_PYR-1 ARPVAFSHGATIMFWTMMNVDNPDLGLLLSHQLPNTGVVVLEGNPEDGWT
MSMEG_6545|M.smegmatis_MC2_155 TDPVAFSHAGAIMTWVAMNVDNPDLGLLSRHPLGNTGHAVVKGNPTGGWT
MAV_4339|M.avium_104 RNPVVFSHANSIMVWTLMNTRNAKDSLMNTHPLPNTGRVVINGNPITGWT
MUL_0919|M.ulcerans_Agy99 NRPVVFSQGTAIMVWTLMNVKNPKTNLLNTHPLPNIGRVVISGNPATGWK
MLBr_00079|M.leprae_Br4923 TGDVVVVSHGAAIRLVSAVLAEVDGRFALENRVNNAESVVLVPVTDGRWS
MAB_0133|M.abscessus_ATCC_1997 TGDVVIVSHGAAIRLVAAALAGVDPGFAVNRHLRNAEAVVLAPVTDGRWS
*. : . . : . : * . : . *.
Mb0776|M.bovis_AF2122/97 LVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVI
Rv0754|M.tuberculosis_H37Rv LVSWDGIPVGP-ASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVI
MMAR_4953|M.marinum_M MVSWDGIPVAP-ATLPTQLFVDVRNLITAPQYAGWDIFYSLFTGNPTTIL
TH_4040|M.thermoresistible__bu LVSWAGVEVSRTPSLPTTLFVRTRDLLVAPQTALYNLGQALRTGDVVTVV
Mflv_4577|M.gilvum_PYR-GCK LVSWAGQAVSADPSLATKLLVNVRDLVVAPQTALYNVGTAFSSGDFETLV
Mvan_5262|M.vanbaalenii_PYR-1 LVSWDGVAVDPDPSFLTKTFVNVRELITTPQTAVYNVKKAFATGDLAAIT
MSMEG_6545|M.smegmatis_MC2_155 LVDWGGINTE----------------------------------------
MAV_4339|M.avium_104 LVDWDGIRDFRS--------------------------------------
MUL_0919|M.ulcerans_Agy99 LVDWDGIRNFG---------------------------------------
MLBr_00079|M.leprae_Br4923 CVRWGALTPPFYPHLHRPDSTLVTDVVMSGRDSLG---------------
MAB_0133|M.abscessus_ATCC_1997 CVHWGDAVAPF-PHQEAAS----AEELAQSADPMG---------------
* *
Mb0776|M.bovis_AF2122/97 NAVRDGADEVGAAVVQ------------FPHAVADDVIDATGHPYLSGLP
Rv0754|M.tuberculosis_H37Rv NAVRDGADEVGAAVVQ------------FPHAVADDVIDATGHPYLSGLP
MMAR_4953|M.marinum_M TAVRDGIEEVGSAVIN------------FPIEVTEDVVNAICG-ATDGLT
TH_4040|M.thermoresistible__bu EALRDGILDVVX-----------------XPGTSPTMMRAATHRR-----
Mflv_4577|M.gilvum_PYR-GCK NAVRDGLIEVTRAVVRFIPDTVRDIVDEFRPSVTEDSLDVTELHRAVVTA
Mvan_5262|M.vanbaalenii_PYR-1 DSFAQAVIDVVLAPVR------------FVGAVATDVLELVFPPAPSVQV
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 IGLPSLIP------------------------------------------
Rv0754|M.tuberculosis_H37Rv IGLPSLIP------------------------------------------
MMAR_4953|M.marinum_M AGAPSLVG------------------------------------------
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK APQDDDEAEPQSVAVAEAETRNGSGVAPAGSTPPSGDEVTGSTDDDEATA
Mvan_5262|M.vanbaalenii_PYR-1 EAPMSAESTTDESDVPADVPDDVVAVAPS--------EDVESRTPEPASD
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 --------------------------------------------------
Rv0754|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4953|M.marinum_M --------------------------------------------------
TH_4040|M.thermoresistible__bu --------------------------------------------------
Mflv_4577|M.gilvum_PYR-GCK SDVVLEDTVDVDTIDVDTVEEDTGASDHAVGNHPDAEADDAAPANGSAKS
Mvan_5262|M.vanbaalenii_PYR-1 EAETREESAAPESEATEPEISASQSEESEVETETTEETTTAG-----TTG
MSMEG_6545|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4339|M.avium_104 --------------------------------------------------
MUL_0919|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00079|M.leprae_Br4923 --------------------------------------------------
MAB_0133|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0776|M.bovis_AF2122/97 -----------------
Rv0754|M.tuberculosis_H37Rv -----------------
MMAR_4953|M.marinum_M -----------------
TH_4040|M.thermoresistible__bu -----------------
Mflv_4577|M.gilvum_PYR-GCK SDDDGDSDDDASERAAA
Mvan_5262|M.vanbaalenii_PYR-1 DDDTDETDDGAAVKEAA
MSMEG_6545|M.smegmatis_MC2_155 -----------------
MAV_4339|M.avium_104 -----------------
MUL_0919|M.ulcerans_Agy99 -----------------
MLBr_00079|M.leprae_Br4923 -----------------
MAB_0133|M.abscessus_ATCC_1997 -----------------