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M. marinum M MMAR_3570 (-)

annotation: PE-PGRS family protein
coordinates: 4388079 - 4390853
length: 924

MSYVIVAPEMLEAAASDLANIGSAIGVANAAAALPTTSVLAAAADEVSAAIAAVFGEHGQAYQAFSAQAT
AFHADFVEALTTGVGSYAAAEATNAGQALLGAVNAPAQALLGRPLIGNGIDGTATNPNGGDGGLLYGNGG
NGYSQTDGGLAGGKGGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNGGVLYGNGGTGGAGGSGTTSYGAA
GVGGNALLFGNGGTGGSGLGGGGNGGNAVFGNGGAGGAGVAGIGGNGGNTFIGTGGAGGAGGGTILGGGS
HAGGDGGSVGLWGSGGVGGAGTTPDADSGYAGGDGGNGGNGGLLYGDGGAGGAGGLGSDYSSLFYNAGNG
GNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYGGHGGNGGNGGTDGLLFGKGGAGGDGGAGGGTTSSGTG
GSGGTGGTGGSSFIGSGGTGGAGGAGGTATGSGASGAGGAGGSGGYNGFIGAGGTGGAGGDGGGGNQGAA
AGDGGSGGTAAGLFGAGGTGGTGGTGGTTTANGGTGGAAGVGGSGGDASSLIALGGTGGVGGVGGAATGG
GATIGADGGTGGNGGNATGLLNFGGSGGAGGAGGAGATTGVQGAGGMGGTPGGQPGAAAVSALLPGGLAS
STAAVGGAYQDLFTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFTLGLAGLPPT
FQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNIKLLGPVGDLLPILRIPGDTAFNVANVIRTP
TDTTVSVEFTSYVPPAITGTFGLPVALTLDAAGSAVTTANAVGTSVTALTNAVQAGDWPAAIGALVDAPA
VVANGFLNGQGTMTVPLSVPIVDSAVINFPVNGILVPPHDYTATVVIAGFSYDVPIMGTPIGGIVPGLLT
YAPQQFANAIGAAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3570--100% (924)PE-PGRS family protein
M. marinum MMMAR_1199-e-17748.55% (791) PE-PGRS family protein
M. marinum MMMAR_5321-e-17551.33% (713) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1679cPE_PGRS300.052.08% (1035) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-12247.64% (571) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1651cPE_PGRS300.051.98% (1035) PE-PGRS family protein
M. leprae Br4923MLBr_01183-6e-1340.23% (87) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-7e-4830.85% (551) hypothetical protein MAB_4284c
M. avium 104MAV_4827-9e-2447.37% (152) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-3e-9936.61% (743) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-7e-4437.67% (361) PUTATIVE -
M. ulcerans Agy99MUL_1145-1e-16147.36% (796) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-12046.69% (574) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb1679c|M.bovis_AF2122/97           --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3570|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3570|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3570|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           --------------------------------------------------
Rv1651c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3570|M.marinum_M               --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           ----------------------------------MS-FLLVEPDLVTAAA
Rv1651c|M.tuberculosis_H37Rv        ----------------------------------MS-FLLVEPDLVTAAA
MMAR_3570|M.marinum_M               ----------------------------------MS-YVIVAPEMLEAAA
MLBr_01183|M.leprae_Br4923          ----------------------------------MPLFLNAEPQALTAAA
MUL_1145|M.ulcerans_Agy99           ----------------------------------MS-YVVASPEYVAAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------MSIIDFILNLF
MAV_4827|M.avium_104                ------------------------------------------MNIVLGVS
                                                                                      

Mb1679c|M.bovis_AF2122/97           ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL
Rv1651c|M.tuberculosis_H37Rv        ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL
MMAR_3570|M.marinum_M               SDLANIGSAIGVANAAAALPTTSVLAAAADEVSAAIAAVFGEHGQAYQAF
MLBr_01183|M.leprae_Br4923          NTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAH
MUL_1145|M.ulcerans_Agy99           SDLAGIGSALSTANAAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQAL
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199      RDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQ
MAV_4827|M.avium_104                MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
                                                                                      

Mb1679c|M.bovis_AF2122/97           NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR
Rv1651c|M.tuberculosis_H37Rv        NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR
MMAR_3570|M.marinum_M               SAQATAFHADFVEALTTGVGSYAAAEATNAG--QALLGAVNAPAQALLGR
MLBr_01183|M.leprae_Br4923          ASQGATNHQDLIQSLLTSSSAYAGTETANHD---SL--------------
MUL_1145|M.ulcerans_Agy99           SEQASAFHLQFVQAMTAGAGAYAGAEAVNASPLQAALDVLNAPAQALFGR
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199      WVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFA
MAV_4827|M.avium_104                REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
                                                                                      

Mb1679c|M.bovis_AF2122/97           PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNGGAGGPDG----GAGGN
Rv1651c|M.tuberculosis_H37Rv        PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNG-----------GAGGN
MMAR_3570|M.marinum_M               PLIGN---GIDGTATNP--NGGDGGLLYGNGGNGYSQTDGG----LAGGK
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           PLIGDGAGGAPGQ------SGGDGGLLYGNGGNGGNGGVG-----QAGGA
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFG-------------
MAV_4827|M.avium_104                LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------D
                                                                                      

Mb1679c|M.bovis_AF2122/97           GGAAGLIGNGGAGGAGG--VGGAGGAGGAGGTGGLLYGNGGAGGNGGS--
Rv1651c|M.tuberculosis_H37Rv        GGAAGLIGNGGAGGAGG--AGGAGGAGGAGGTGGLLYGNGGAGGNGGS--
MMAR_3570|M.marinum_M               GGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNGGVLYGNGGTGGAGGSGT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GGAAGLIGNGGSGGIGG--PGTTGLAGGAGGSGGWLFGNGGTGGRGGIGT
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG----NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG----NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQ--STAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu      NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199      NRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG----
MAV_4827|M.avium_104                VYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVG-----------
                                                                                      

Mb1679c|M.bovis_AF2122/97           -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
Rv1651c|M.tuberculosis_H37Rv        -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG
MMAR_3570|M.marinum_M               TSYGAAG-VGGNAL-LFGNGGTGGSGLGG---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           TGIGGIGGTGGDAVGLFGHGGTGGTGGNGPDIFIAGG-------------
Mflv_5091|M.gilvum_PYR-GCK          --AVGAAGAAG------TVGTAGATGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1       --AIGTAGVAG------AAGTAGATGGTG---------------------
MSMEG_0868|M.smegmatis_MC2_155      GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG--------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA
Rv1651c|M.tuberculosis_H37Rv        LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA
MMAR_3570|M.marinum_M               ----------------------GGNGGNAVFGNGGAGG---AGVAGIGGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           -------------------AGGSGGTGGLLFGNGGAGGGAPWGGADGGAG
Mflv_5091|M.gilvum_PYR-GCK          --------------------TGANGGAGGVGGVGGTGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------VGGNGGAGQAGGIGGTGAAG----------
MSMEG_0868|M.smegmatis_MC2_155      ------------------TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGA
TH_3810|M.thermoresistible__bu      --------------------NGGNVGFFSLFNLGG---------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------SNVGVDQSQTRVGGDYTN-----------
MAV_4827|M.avium_104                ----------------------SGVDVAPLKQVLQTTT------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA
Rv1651c|M.tuberculosis_H37Rv        GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA
MMAR_3570|M.marinum_M               GGNTFIGTGGAGGAGGGTILGGGSHAG---GDGGSVGLWGSGGVGGAG--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GDARLIGNGGGGGYEGSLGVLSGGTAGPGGDGGNAVGLIGNGGAGGAG--
Mflv_5091|M.gilvum_PYR-GCK          ----AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAV
Mvan_1264|M.vanbaalenii_PYR-1       ----AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGA
MSMEG_0868|M.smegmatis_MC2_155      VSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGA
TH_3810|M.thermoresistible__bu      -----AGGWGGSGVDG---------------------VDVVGGNP-----
MAB_4284c|M.abscessus_ATCC_199      -----VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTT
MAV_4827|M.avium_104                ----FLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAV
                                                                                      

Mb1679c|M.bovis_AF2122/97           ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD
Rv1651c|M.tuberculosis_H37Rv        ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD
MMAR_3570|M.marinum_M               TTPDADSGYAGGDGGNG------------GNGGLLYGDGGAGGAGGLGSD
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --AAGLSGVTGGIGGNG------------GNGAQLFGNGGAGGAGGQS--
Mflv_5091|M.gilvum_PYR-GCK          GGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDADS
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDATS
MSMEG_0868|M.smegmatis_MC2_155      DSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALV
TH_3810|M.thermoresistible__bu      -------------------------------------DGGTPG-------
MAB_4284c|M.abscessus_ATCC_199      NTEIGSHNQANIGTSTS--------------AGGSAAVGGNAGLAGNAG-
MAV_4827|M.avium_104                DQYSLPDYLYVPVDPEP--------------GDDELAYSAVGEEDAESPT
                                                                                      

Mb1679c|M.bovis_AF2122/97           TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG
Rv1651c|M.tuberculosis_H37Rv        TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG
MMAR_3570|M.marinum_M               YSSLFYNAGNGGNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYG--GHGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           ------QLASGGTGGSGGMAALFGNGGAGGAAGVSLSGAPGTGGNGGSAQ
Mflv_5091|M.gilvum_PYR-GCK          MGS------------------AGATGGKGGNGGNGGRGGLFG--------
Mvan_1264|M.vanbaalenii_PYR-1       MGE------------------AGATGGKGGNGGNGGRGSLFG--------
MSMEG_0868|M.smegmatis_MC2_155      MAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSAT
TH_3810|M.thermoresistible__bu      -----------------------AHGESHTPGVYTDRQ------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------LAGNAGLAGNAGLAGNAGLAG--------
MAV_4827|M.avium_104                VVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIG------
                                                                                      

Mb1679c|M.bovis_AF2122/97           AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG
Rv1651c|M.tuberculosis_H37Rv        AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG
MMAR_3570|M.marinum_M               NGGNGGTDGLLFGKGGAG------GDGGAGGGTT-SSGTGGSGGTGGTGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           FMGDGDSGGLGDSGGSAG------AAG--AGGLIGNPLDVVNAPTEALLG
Mflv_5091|M.gilvum_PYR-GCK          -------KGGNAGNGAD----------------------GGTGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1       -------RGGNAGNGGN----------------------GGTGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155      SGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNG
TH_3810|M.thermoresistible__bu      -------------------------------------------GEDGEDG
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------NAGLAGNAGLAG
MAV_4827|M.avium_104                ------------------------------------IRTTGTVALQPTPN
                                                                                      

Mb1679c|M.bovis_AF2122/97           SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL
Rv1651c|M.tuberculosis_H37Rv        SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL
MMAR_3570|M.marinum_M               SSFIGSGGTGGAG-----------GAG----------GTATGSG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           RPLIGDGADGAPG-----------ESGQDGG----LLYGNGGNGGNGLSG
Mflv_5091|M.gilvum_PYR-GCK          TGG-TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       TGG-TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      TGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGAN
TH_3810|M.thermoresistible__bu      TGTGIGGRGGNGG----------------SSSGTHPMAEDG--------E
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGN---------------------AGLAGNAGLAGNAGLA
MAV_4827|M.avium_104                QHLIVPTEQAPAP---------------------PPVQASAPQPKISVPE
                                                                                      

Mb1679c|M.bovis_AF2122/97           GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG
Rv1651c|M.tuberculosis_H37Rv        GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG
MMAR_3570|M.marinum_M               -ASGAGGAGGSG----GYNG---FIGAGGTGGAGGDGGGG----NQGAAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           QAGGAGGAAGLI----GNGGNGGIGGPGTTGMSGGAGGAGGWLIGNGGHG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKG
TH_3810|M.thermoresistible__bu      HVKALDGRPGLD---GGNGSHGGNGGHGGRGGFLGIGGSG-------GWG
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLA----GNAGLAGNAGLAGNAGLAGNAGLAG----NAGLA
MAV_4827|M.avium_104                PVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP
                                                                                      

Mb1679c|M.bovis_AF2122/97           GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG
Rv1651c|M.tuberculosis_H37Rv        GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG
MMAR_3570|M.marinum_M               GDGGSGGTAAG------------------LFGAGGTGGTGGTGG--TTTA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GIGGLG------------------------IGIGDSGGAGGAGG--AAIG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTG----------------------GTGGTGGTGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTG----------------------GTGGTGGTGGAG-------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGTYV-------------DPSHTGAGGNGGNGGAGRIRVNNG
TH_3810|M.thermoresistible__bu      GHGGNGGD------------------------TDADGGNGGDG-------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAG-------------------LAGNAAVAGNAAVAG------
MAV_4827|M.avium_104                VPVPVRIPVPDP------------------VSPPQLLAPPRLSVPQPVQP
                                                                                      

Mb1679c|M.bovis_AF2122/97           GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG
Rv1651c|M.tuberculosis_H37Rv        GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG
MMAR_3570|M.marinum_M               NGGTGGAAGVGGSGGDASSLIALGGTGGVGGVGGAATGGGATIGADGGTG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           LFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSWG-GAAA
Mflv_5091|M.gilvum_PYR-GCK          ----DGTGGTGGTGG----TGGQGGQGGQGG-----------------TG
Mvan_1264|M.vanbaalenii_PYR-1       ----DGLGGTGGTGG----TGGFGGQGGQGG-----------------TG
MSMEG_0868|M.smegmatis_MC2_155      TATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATG
TH_3810|M.thermoresistible__bu      --------GNGGSAG---------------------------------RG
MAB_4284c|M.abscessus_ATCC_199      ---NAAVAGNAAVGG----VLNTGVSGAIGG----------------SSH
MAV_4827|M.avium_104                PVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP-------------PKPD
                                                                                      

Mb1679c|M.bovis_AF2122/97           GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP
Rv1651c|M.tuberculosis_H37Rv        GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP
MMAR_3570|M.marinum_M               GNGGNATGLLNFGGSG-----------------------GAGGAGGAGAT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GAGGDAG-LIDNGGDG-----------------------DSAGVLRQ---
Mflv_5091|M.gilvum_PYR-GCK          GTGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQ
Mvan_1264|M.vanbaalenii_PYR-1       GTGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQ
MSMEG_0868|M.smegmatis_MC2_155      GDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGH
TH_3810|M.thermoresistible__bu      GTGGLRGVFGINGGNG------------------------RAGLGGRGXX
MAB_4284c|M.abscessus_ATCC_199      VGGAINESLGGSGSVG-----------------------GSTAVGGGAHT
MAV_4827|M.avium_104                GPGNYGGGHVPTPGAG-------------------------GSGGSGGGH
                                                                                      

Mb1679c|M.bovis_AF2122/97           AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL
Rv1651c|M.tuberculosis_H37Rv        AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL
MMAR_3570|M.marinum_M               TGVQGAGGMGGTP------GGQPGAAAVSALLPGGLASSTAAVGGAYQDL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           ---NGIGGHGGAGGSLFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWA
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGL
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQ
MSMEG_0868|M.smegmatis_MC2_155      GGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANA
TH_3810|M.thermoresistible__bu      XXGGGVGAAVRSG---------------NGVFSGGGGTPSAGFGVPTTIQ
MAB_4284c|M.abscessus_ATCC_199      GVGGGVSTGVGVG-----------SHVGGGISESLGGSGSVGGSTAVGGG
MAV_4827|M.avium_104                VPTPGAGGSGGSG----------------GGHVPTPGTGGPGGTGGSGGG
                                                                                      

Mb1679c|M.bovis_AF2122/97           IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI
Rv1651c|M.tuberculosis_H37Rv        IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI
MMAR_3570|M.marinum_M               FTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFTL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           IYNSFAGDDGSGGTAIGNGGDGGANIVS-----SGFILGAGGGGNGGNAV
Mflv_5091|M.gilvum_PYR-GCK          GGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGAS
Mvan_1264|M.vanbaalenii_PYR-1       GGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGAS
MSMEG_0868|M.smegmatis_MC2_155      ANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTAT
TH_3810|M.thermoresistible__bu      FPAGSCTSRAVSREG------------------------IMPSSRAASAR
MAB_4284c|M.abscessus_ATCC_199      AHTGVGGGVSTGVGVGSHVGGGISESLGG--------SGSVGGSTAVGGG
MAV_4827|M.avium_104                HVPTPGAGTPGGSGG-----------------------GHLPFPGAGSTP
                                                                                      

Mb1679c|M.bovis_AF2122/97           GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL
Rv1651c|M.tuberculosis_H37Rv        GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL
MMAR_3570|M.marinum_M               GLAGLPPTFQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNIKL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GLIGN----------------GGAGGTGADGFSTALGS------------
Mflv_5091|M.gilvum_PYR-GCK          GGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1       GGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAG
MSMEG_0868|M.smegmatis_MC2_155      AGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATG
TH_3810|M.thermoresistible__bu      AG---------------------------AACASSTSRSRRSFCCSRA--
MAB_4284c|M.abscessus_ATCC_199      AHTGVG----------------GGVNTGVGVGSHVGGGISESLGGSGSVG
MAV_4827|M.avium_104                GGSG----------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG
Rv1651c|M.tuberculosis_H37Rv        LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG
MMAR_3570|M.marinum_M               LGPVGDLLPILRIPGDTAFNVANVIRTPTDTTVSVEFTSYVPPAITGTFG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
Mvan_1264|M.vanbaalenii_PYR-1       SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
MSMEG_0868|M.smegmatis_MC2_155      GAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G-------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb1679c|M.bovis_AF2122/97           LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV
Rv1651c|M.tuberculosis_H37Rv        LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV
MMAR_3570|M.marinum_M               LPVALTLDAAGSAVTTANAVGTSVTALTNAVQAGDWPAAIGALVDAPAVV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           --------DGGNGGTGAWLLGNGGAGGSGGSTAGVHPAGDGGNSGMSALI
Mflv_5091|M.gilvum_PYR-GCK          G--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEG
Mvan_1264|M.vanbaalenii_PYR-1       G--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEG
MSMEG_0868|M.smegmatis_MC2_155      GSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------STAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINES
MAV_4827|M.avium_104                -------------GGHLPTPGAGTPGGGLGGFGG-----------GHAPA
                                                                                      

Mb1679c|M.bovis_AF2122/97           ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI
Rv1651c|M.tuberculosis_H37Rv        ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI
MMAR_3570|M.marinum_M               ANGFLNGQGTMTVPLSVPIVD--SAVINFPVNGILVPPHDYTATVVIAGF
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MUL_1145|M.ulcerans_Agy99           GNGGAGGSAGVSPTGVFPSNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGT
Mflv_5091|M.gilvum_PYR-GCK          GEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1       GEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGS
MSMEG_0868|M.smegmatis_MC2_155      NTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      MNSSINASHSSSMN----------ESFGSSMGSHGAAGTGFEAQGHAQGH
MAV_4827|M.avium_104                PGGGLGGGGG----------------HAPAPGGGLGGFGGGHSGGGLGGL
                                                                                      

Mb1679c|M.bovis_AF2122/97           GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--
Rv1651c|M.tuberculosis_H37Rv        GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--
MMAR_3570|M.marinum_M               S-YDVPIMGTPIGGIVPGLLTYAPQQFANAIGAAG
MLBr_01183|M.leprae_Br4923          -----------------------------------
MUL_1145|M.ulcerans_Agy99           GGSLAGHDGSDGD----------------------
Mflv_5091|M.gilvum_PYR-GCK          GGSGGSGGSGGAAGDSDD-----------------
Mvan_1264|M.vanbaalenii_PYR-1       GGSGGAGGSGGAAGDSD------------------
MSMEG_0868|M.smegmatis_MC2_155      GGADGTPGTAGTTGANNP-----------------
TH_3810|M.thermoresistible__bu      -----------------------------------
MAB_4284c|M.abscessus_ATCC_199      ASETAHTTLPGAEHH--------------------
MAV_4827|M.avium_104                GGGHK------------------------------