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MSYVIVAPEMLEAAASDLANIGSAIGVANAAAALPTTSVLAAAADEVSAAIAAVFGEHGQAYQAFSAQAT AFHADFVEALTTGVGSYAAAEATNAGQALLGAVNAPAQALLGRPLIGNGIDGTATNPNGGDGGLLYGNGG NGYSQTDGGLAGGKGGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNGGVLYGNGGTGGAGGSGTTSYGAA GVGGNALLFGNGGTGGSGLGGGGNGGNAVFGNGGAGGAGVAGIGGNGGNTFIGTGGAGGAGGGTILGGGS HAGGDGGSVGLWGSGGVGGAGTTPDADSGYAGGDGGNGGNGGLLYGDGGAGGAGGLGSDYSSLFYNAGNG GNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYGGHGGNGGNGGTDGLLFGKGGAGGDGGAGGGTTSSGTG GSGGTGGTGGSSFIGSGGTGGAGGAGGTATGSGASGAGGAGGSGGYNGFIGAGGTGGAGGDGGGGNQGAA AGDGGSGGTAAGLFGAGGTGGTGGTGGTTTANGGTGGAAGVGGSGGDASSLIALGGTGGVGGVGGAATGG GATIGADGGTGGNGGNATGLLNFGGSGGAGGAGGAGATTGVQGAGGMGGTPGGQPGAAAVSALLPGGLAS STAAVGGAYQDLFTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFTLGLAGLPPT FQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNIKLLGPVGDLLPILRIPGDTAFNVANVIRTP TDTTVSVEFTSYVPPAITGTFGLPVALTLDAAGSAVTTANAVGTSVTALTNAVQAGDWPAAIGALVDAPA VVANGFLNGQGTMTVPLSVPIVDSAVINFPVNGILVPPHDYTATVVIAGFSYDVPIMGTPIGGIVPGLLT YAPQQFANAIGAAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3570 | - | - | 100% (924) | PE-PGRS family protein |
M. marinum M | MMAR_1199 | - | e-177 | 48.55% (791) | PE-PGRS family protein |
M. marinum M | MMAR_5321 | - | e-175 | 51.33% (713) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1679c | PE_PGRS30 | 0.0 | 52.08% (1035) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-122 | 47.64% (571) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1651c | PE_PGRS30 | 0.0 | 51.98% (1035) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 6e-13 | 40.23% (87) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 7e-48 | 30.85% (551) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 9e-24 | 47.37% (152) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-99 | 36.61% (743) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 7e-44 | 37.67% (361) | PUTATIVE - |
M. ulcerans Agy99 | MUL_1145 | - | 1e-161 | 47.36% (796) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-120 | 46.69% (574) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3570|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3570|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3570|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 -------------------------------------------------- Rv1651c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3570|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 ----------------------------------MS-FLLVEPDLVTAAA Rv1651c|M.tuberculosis_H37Rv ----------------------------------MS-FLLVEPDLVTAAA MMAR_3570|M.marinum_M ----------------------------------MS-YVIVAPEMLEAAA MLBr_01183|M.leprae_Br4923 ----------------------------------MPLFLNAEPQALTAAA MUL_1145|M.ulcerans_Agy99 ----------------------------------MS-YVVASPEYVAAAA Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------MSIIDFILNLF MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS Mb1679c|M.bovis_AF2122/97 ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL Rv1651c|M.tuberculosis_H37Rv ANLAGIRSALSEAAAAASTPTTALASAGADEVSAAVSRLFGAYGQQFQAL MMAR_3570|M.marinum_M SDLANIGSAIGVANAAAALPTTSVLAAAADEVSAAIAAVFGEHGQAYQAF MLBr_01183|M.leprae_Br4923 NTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAH MUL_1145|M.ulcerans_Agy99 SDLAGIGSALSTANAAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQAL Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 RDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQ MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT Mb1679c|M.bovis_AF2122/97 NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR Rv1651c|M.tuberculosis_H37Rv NARAATFHAEFVSLLNGGAAAYTGAEAASVSSMQALLDAVNAPTQTLLGR MMAR_3570|M.marinum_M SAQATAFHADFVEALTTGVGSYAAAEATNAG--QALLGAVNAPAQALLGR MLBr_01183|M.leprae_Br4923 ASQGATNHQDLIQSLLTSSSAYAGTETANHD---SL-------------- MUL_1145|M.ulcerans_Agy99 SEQASAFHLQFVQAMTAGAGAYAGAEAVNASPLQAALDVLNAPAQALFGR Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_4284c|M.abscessus_ATCC_199 WVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFA MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA Mb1679c|M.bovis_AF2122/97 PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNGGAGGPDG----GAGGN Rv1651c|M.tuberculosis_H37Rv PLIGNGADGVAGTGSNAGGNGGPGGILYGNGGNG-----------GAGGN MMAR_3570|M.marinum_M PLIGN---GIDGTATNP--NGGDGGLLYGNGGNGYSQTDGG----LAGGK MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 PLIGDGAGGAPGQ------SGGDGGLLYGNGGNGGNGGVG-----QAGGA Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFG------------- MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP------------D Mb1679c|M.bovis_AF2122/97 GGAAGLIGNGGAGGAGG--VGGAGGAGGAGGTGGLLYGNGGAGGNGGS-- Rv1651c|M.tuberculosis_H37Rv GGAAGLIGNGGAGGAGG--AGGAGGAGGAGGTGGLLYGNGGAGGNGGS-- MMAR_3570|M.marinum_M GGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNGGVLYGNGGTGGAGGSGT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GGAAGLIGNGGSGGIGG--PGTTGLAGGAGGSGGWLFGNGGTGGRGGIGT Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG----NAGLPGKAGDAGGAG-------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG----NAGLPGAAGAAGGAG-------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQ--STAAGPGKGGGGGGGGGGAILIGANGGTVD TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG--------------------------------- MAB_4284c|M.abscessus_ATCC_199 NRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG---- MAV_4827|M.avium_104 VYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVG----------- Mb1679c|M.bovis_AF2122/97 -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG Rv1651c|M.tuberculosis_H37Rv -AAAAGG-AGGNAL-LFGNGGNGGSGASGGAAGHAGTIFGNGGNAGAGSG MMAR_3570|M.marinum_M TSYGAAG-VGGNAL-LFGNGGTGGSGLGG--------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 TGIGGIGGTGGDAVGLFGHGGTGGTGGNGPDIFIAGG------------- Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG--------------------- Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG--------------------- MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG-------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA Rv1651c|M.tuberculosis_H37Rv LAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGGDGG---SSTVAAGGA MMAR_3570|M.marinum_M ----------------------GGNGGNAVFGNGGAGG---AGVAGIGGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------AGGSGGTGGLLFGNGGAGGGAPWGGADGGAG Mflv_5091|M.gilvum_PYR-GCK --------------------TGANGGAGGVGGVGGTGAAG---------- Mvan_1264|M.vanbaalenii_PYR-1 --------------------VGGNGGAGQAGGIGGTGAAG---------- MSMEG_0868|M.smegmatis_MC2_155 ------------------TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGA TH_3810|M.thermoresistible__bu --------------------NGGNVGFFSLFNLGG--------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------SNVGVDQSQTRVGGDYTN----------- MAV_4827|M.avium_104 ----------------------SGVDVAPLKQVLQTTT------------ Mb1679c|M.bovis_AF2122/97 GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA Rv1651c|M.tuberculosis_H37Rv GGNTLVGNGGAGGAGGTSGLTGSGVAG---GAGGSVGLWGSGGAGGDGGA MMAR_3570|M.marinum_M GGNTFIGTGGAGGAGGGTILGGGSHAG---GDGGSVGLWGSGGVGGAG-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GDARLIGNGGGGGYEGSLGVLSGGTAGPGGDGGNAVGLIGNGGAGGAG-- Mflv_5091|M.gilvum_PYR-GCK ----AAGGAGGLGETGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAV Mvan_1264|M.vanbaalenii_PYR-1 ----AAGQAGTAGETGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGA MSMEG_0868|M.smegmatis_MC2_155 VSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGA TH_3810|M.thermoresistible__bu -----AGGWGGSGVDG---------------------VDVVGGNP----- MAB_4284c|M.abscessus_ATCC_199 -----VSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTT MAV_4827|M.avium_104 ----FLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAV Mb1679c|M.bovis_AF2122/97 ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD Rv1651c|M.tuberculosis_H37Rv ATSLLGVGMNAGAGGAG------------GNAGLLYGNGGAGGAGGNGGD MMAR_3570|M.marinum_M TTPDADSGYAGGDGGNG------------GNGGLLYGDGGAGGAGGLGSD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 --AAGLSGVTGGIGGNG------------GNGAQLFGNGGAGGAGGQS-- Mflv_5091|M.gilvum_PYR-GCK GGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDADS Mvan_1264|M.vanbaalenii_PYR-1 GGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDATS MSMEG_0868|M.smegmatis_MC2_155 DSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALV TH_3810|M.thermoresistible__bu -------------------------------------DGGTPG------- MAB_4284c|M.abscessus_ATCC_199 NTEIGSHNQANIGTSTS--------------AGGSAAVGGNAGLAGNAG- MAV_4827|M.avium_104 DQYSLPDYLYVPVDPEP--------------GDDELAYSAVGEEDAESPT Mb1679c|M.bovis_AF2122/97 TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG Rv1651c|M.tuberculosis_H37Rv TTVPLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGG MMAR_3570|M.marinum_M YSSLFYNAGNGGNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYG--GHGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 ------QLASGGTGGSGGMAALFGNGGAGGAAGVSLSGAPGTGGNGGSAQ Mflv_5091|M.gilvum_PYR-GCK MGS------------------AGATGGKGGNGGNGGRGGLFG-------- Mvan_1264|M.vanbaalenii_PYR-1 MGE------------------AGATGGKGGNGGNGGRGSLFG-------- MSMEG_0868|M.smegmatis_MC2_155 MAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSAT TH_3810|M.thermoresistible__bu -----------------------AHGESHTPGVYTDRQ------------ MAB_4284c|M.abscessus_ATCC_199 ---------------------LAGNAGLAGNAGLAGNAGLAG-------- MAV_4827|M.avium_104 VVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIG------ Mb1679c|M.bovis_AF2122/97 AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG Rv1651c|M.tuberculosis_H37Rv AGGAGGVGGLLYGNGGNG------GAGGIGGAAINILANAGAGGAGGAAG MMAR_3570|M.marinum_M NGGNGGTDGLLFGKGGAG------GDGGAGGGTT-SSGTGGSGGTGGTGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 FMGDGDSGGLGDSGGSAG------AAG--AGGLIGNPLDVVNAPTEALLG Mflv_5091|M.gilvum_PYR-GCK -------KGGNAGNGAD----------------------GGTGGAGGAGG Mvan_1264|M.vanbaalenii_PYR-1 -------RGGNAGNGGN----------------------GGTGGNGGNGG MSMEG_0868|M.smegmatis_MC2_155 SGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNG TH_3810|M.thermoresistible__bu -------------------------------------------GEDGEDG MAB_4284c|M.abscessus_ATCC_199 --------------------------------------NAGLAGNAGLAG MAV_4827|M.avium_104 ------------------------------------IRTTGTVALQPTPN Mb1679c|M.bovis_AF2122/97 SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL Rv1651c|M.tuberculosis_H37Rv SSFIGNGGNGGAG-----------GAGGAAALFSSGVGGAGGSGGTALLL MMAR_3570|M.marinum_M SSFIGSGGTGGAG-----------GAG----------GTATGSG------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 RPLIGDGADGAPG-----------ESGQDGG----LLYGNGGNGGNGLSG Mflv_5091|M.gilvum_PYR-GCK TGG-TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 TGG-TGGNGGTGG-----------------TGGTGGIGGAGSTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 TGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGAN TH_3810|M.thermoresistible__bu TGTGIGGRGGNGG----------------SSSGTHPMAEDG--------E MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN---------------------AGLAGNAGLAGNAGLA MAV_4827|M.avium_104 QHLIVPTEQAPAP---------------------PPVQASAPQPKISVPE Mb1679c|M.bovis_AF2122/97 GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG Rv1651c|M.tuberculosis_H37Rv GSGGAGGNGGTG----GANSGSLFASPGGTGGAGGHGGAGGLIWGNGGAG MMAR_3570|M.marinum_M -ASGAGGAGGSG----GYNG---FIGAGGTGGAGGDGGGG----NQGAAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 QAGGAGGAAGLI----GNGGNGGIGGPGTTGMSGGAGGAGGWLIGNGGHG Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTG MSMEG_0868|M.smegmatis_MC2_155 GNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKG TH_3810|M.thermoresistible__bu HVKALDGRPGLD---GGNGSHGGNGGHGGRGGFLGIGGSG-------GWG MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLA----GNAGLAGNAGLAGNAGLAGNAGLAG----NAGLA MAV_4827|M.avium_104 PVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP Mb1679c|M.bovis_AF2122/97 GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG Rv1651c|M.tuberculosis_H37Rv GNGGNGGTTADGALEGGTGGIGGTGGSAIAFGNGGQGGAGGTGG--DHSG MMAR_3570|M.marinum_M GDGGSGGTAAG------------------LFGAGGTGGTGGTGG--TTTA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GIGGLG------------------------IGIGDSGGAGGAGG--AAIG Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTG----------------------GTGGTGGTGGAG------- Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG----------------------GTGGTGGTGGAG------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGTYV-------------DPSHTGAGGNGGNGGAGRIRVNNG TH_3810|M.thermoresistible__bu GHGGNGGD------------------------TDADGGNGGDG------- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG-------------------LAGNAAVAGNAAVAG------ MAV_4827|M.avium_104 VPVPVRIPVPDP------------------VSPPQLLAPPRLSVPQPVQP Mb1679c|M.bovis_AF2122/97 GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG Rv1651c|M.tuberculosis_H37Rv GNGIGGKGGASGNGGNAGQVFGDGGTGGTGGAGGAGSG--TKAGGTGSDG MMAR_3570|M.marinum_M NGGTGGAAGVGGSGGDASSLIALGGTGGVGGVGGAATGGGATIGADGGTG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 LFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSWG-GAAA Mflv_5091|M.gilvum_PYR-GCK ----DGTGGTGGTGG----TGGQGGQGGQGG-----------------TG Mvan_1264|M.vanbaalenii_PYR-1 ----DGLGGTGGTGG----TGGFGGQGGQGG-----------------TG MSMEG_0868|M.smegmatis_MC2_155 TATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATG TH_3810|M.thermoresistible__bu --------GNGGSAG---------------------------------RG MAB_4284c|M.abscessus_ATCC_199 ---NAAVAGNAAVGG----VLNTGVSGAIGG----------------SSH MAV_4827|M.avium_104 PVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP-------------PKPD Mb1679c|M.bovis_AF2122/97 GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP Rv1651c|M.tuberculosis_H37Rv GHGGNAT-LIGNGGDG-----------------------GAGGAGGAGSP MMAR_3570|M.marinum_M GNGGNATGLLNFGGSG-----------------------GAGGAGGAGAT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GAGGDAG-LIDNGGDG-----------------------DSAGVLRQ--- Mflv_5091|M.gilvum_PYR-GCK GTGGQGG-LGGGGGTG-----------------------GQGGTGGTGGQ Mvan_1264|M.vanbaalenii_PYR-1 GTGGQGG-LGGVGGTG-----------------------GTGGTGGTGGQ MSMEG_0868|M.smegmatis_MC2_155 GDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGH TH_3810|M.thermoresistible__bu GTGGLRGVFGINGGNG------------------------RAGLGGRGXX MAB_4284c|M.abscessus_ATCC_199 VGGAINESLGGSGSVG-----------------------GSTAVGGGAHT MAV_4827|M.avium_104 GPGNYGGGHVPTPGAG-------------------------GSGGSGGGH Mb1679c|M.bovis_AF2122/97 AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL Rv1651c|M.tuberculosis_H37Rv AGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYEDL MMAR_3570|M.marinum_M TGVQGAGGMGGTP------GGQPGAAAVSALLPGGLASSTAAVGGAYQDL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 ---NGIGGHGGAGGSLFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWA Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGL Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQ MSMEG_0868|M.smegmatis_MC2_155 GGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANA TH_3810|M.thermoresistible__bu XXGGGVGAAVRSG---------------NGVFSGGGGTPSAGFGVPTTIQ MAB_4284c|M.abscessus_ATCC_199 GVGGGVSTGVGVG-----------SHVGGGISESLGGSGSVGGSTAVGGG MAV_4827|M.avium_104 VPTPGAGGSGGSG----------------GGHVPTPGTGGPGGTGGSGGG Mb1679c|M.bovis_AF2122/97 IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI Rv1651c|M.tuberculosis_H37Rv IANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFAI MMAR_3570|M.marinum_M FTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFTL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 IYNSFAGDDGSGGTAIGNGGDGGANIVS-----SGFILGAGGGGNGGNAV Mflv_5091|M.gilvum_PYR-GCK GGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGAS Mvan_1264|M.vanbaalenii_PYR-1 GGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGAS MSMEG_0868|M.smegmatis_MC2_155 ANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTAT TH_3810|M.thermoresistible__bu FPAGSCTSRAVSREG------------------------IMPSSRAASAR MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTGVGVGSHVGGGISESLGG--------SGSVGGSTAVGGG MAV_4827|M.avium_104 HVPTPGAGTPGGSGG-----------------------GHLPFPGAGSTP Mb1679c|M.bovis_AF2122/97 GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL Rv1651c|M.tuberculosis_H37Rv GLAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNILL MMAR_3570|M.marinum_M GLAGLPPTFQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNIKL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GLIGN----------------GGAGGTGADGFSTALGS------------ Mflv_5091|M.gilvum_PYR-GCK GGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAG Mvan_1264|M.vanbaalenii_PYR-1 GGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAG MSMEG_0868|M.smegmatis_MC2_155 AGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATG TH_3810|M.thermoresistible__bu AG---------------------------AACASSTSRSRRSFCCSRA-- MAB_4284c|M.abscessus_ATCC_199 AHTGVG----------------GGVNTGVGVGSHVGGGISESLGGSGSVG MAV_4827|M.avium_104 GGSG---------------------------------------------- Mb1679c|M.bovis_AF2122/97 LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG Rv1651c|M.tuberculosis_H37Rv LGPVGDLFPILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGVM-TFG MMAR_3570|M.marinum_M LGPVGDLLPILRIPGDTAFNVANVIRTPTDTTVSVEFTSYVPPAITGTFG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT Mvan_1264|M.vanbaalenii_PYR-1 SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT MSMEG_0868|M.smegmatis_MC2_155 GAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 G------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV Rv1651c|M.tuberculosis_H37Rv LPLAMTLNAVGSPITTAIAFAESTTAFVSAVQAGNLQAAAAALVGAPANV MMAR_3570|M.marinum_M LPVALTLDAAGSAVTTANAVGTSVTALTNAVQAGDWPAAIGALVDAPAVV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 --------DGGNGGTGAWLLGNGGAGGSGGSTAGVHPAGDGGNSGMSALI Mflv_5091|M.gilvum_PYR-GCK G--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEG Mvan_1264|M.vanbaalenii_PYR-1 G--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEG MSMEG_0868|M.smegmatis_MC2_155 GSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------STAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINES MAV_4827|M.avium_104 -------------GGHLPTPGAGTPGGGLGGFGG-----------GHAPA Mb1679c|M.bovis_AF2122/97 ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI Rv1651c|M.tuberculosis_H37Rv ANGFLNGEARLPLALPTSATGGIPVTVEVPVGGILAPLQPFQATAVIPVI MMAR_3570|M.marinum_M ANGFLNGQGTMTVPLSVPIVD--SAVINFPVNGILVPPHDYTATVVIAGF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MUL_1145|M.ulcerans_Agy99 GNGGAGGSAGVSPTGVFPSNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGT Mflv_5091|M.gilvum_PYR-GCK GEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGS Mvan_1264|M.vanbaalenii_PYR-1 GEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGS MSMEG_0868|M.smegmatis_MC2_155 NTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 MNSSINASHSSSMN----------ESFGSSMGSHGAAGTGFEAQGHAQGH MAV_4827|M.avium_104 PGGGLGGGGG----------------HAPAPGGGLGGFGGGHSGGGLGGL Mb1679c|M.bovis_AF2122/97 GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP-- Rv1651c|M.tuberculosis_H37Rv GPVTVTLEGTPAGGIVPALVNYAPTQLAQAIAP-- MMAR_3570|M.marinum_M S-YDVPIMGTPIGGIVPGLLTYAPQQFANAIGAAG MLBr_01183|M.leprae_Br4923 ----------------------------------- MUL_1145|M.ulcerans_Agy99 GGSLAGHDGSDGD---------------------- Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGAAGDSDD----------------- Mvan_1264|M.vanbaalenii_PYR-1 GGSGGAGGSGGAAGDSD------------------ MSMEG_0868|M.smegmatis_MC2_155 GGADGTPGTAGTTGANNP----------------- TH_3810|M.thermoresistible__bu ----------------------------------- MAB_4284c|M.abscessus_ATCC_199 ASETAHTTLPGAEHH-------------------- MAV_4827|M.avium_104 GGGHK------------------------------