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VRTDRDRWDLATSVGATATMVAAQRALAADPQYALIDDPYAAPLVRAVGIDVYTRLVNGQIPVDVESGFD PARMAEAMACRTRFYDQFFVEATRSGISQVVILASGLDARAYRLDWPAGTVVYEVDMPEVIEFKTLTLAD LGAEPTAERRTVAVDLRDDWAAALQAAGFDKDVPSAWSAEGLLVYLPDDAQDALFDNITALSATGSRLAF EFVPDTAVFNDERWRSHHARMSELGFEIDFNDLVYHGQRSHVIDHLARDGWQSASHTAKELHAANGFDYP DDDIAAVFADITYTSAVLGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4850 | - | - | 100% (301) | O-methyltransferase |
| M. marinum M | MMAR_1068 | - | 1e-88 | 55.41% (296) | O-methyltransferase |
| M. marinum M | MMAR_3534 | - | 1e-86 | 57.14% (308) | O-methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0853 | - | 1e-139 | 78.74% (301) | hypothetical protein Mb0853 |
| M. gilvum PYR-GCK | Mflv_5025 | - | 2e-83 | 54.46% (303) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0830 | - | 1e-139 | 78.74% (301) | hypothetical protein Rv0830 |
| M. leprae Br4923 | MLBr_02640 | - | 1e-61 | 47.54% (284) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 3e-83 | 53.44% (305) | hypothetical protein MAB_3787 |
| M. avium 104 | MAV_0778 | - | 1e-134 | 77.33% (300) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1481 | - | 8e-90 | 56.82% (308) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 4e-85 | 54.82% (301) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0450 | - | 1e-168 | 96.35% (301) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 8e-84 | 54.82% (301) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4850|M.marinum_M MVRTDRDRWDLATSVGATATMVAAQRALAADPQYALIDDPYAAPLVRAVG
MUL_0450|M.ulcerans_Agy99 MVRTDRDRWDLATSVGATATMVAAQRALAADPQYALIDDPYAAPLVRAVD
Mb0853|M.bovis_AF2122/97 MVRADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVG
Rv0830|M.tuberculosis_H37Rv MVRADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVG
MAV_0778|M.avium_104 MARTDHDRWDLATSVGATATMVAAQRALSSDAN--LIDDPYAAPLVRAVG
Mflv_5025|M.gilvum_PYR-GCK MARTPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAVG
Mvan_1344|M.vanbaalenii_PYR-1 MARTADDSWDPASSVGATATMVAAGRAAASADPDPLINDPYAEPLVRAVG
MAB_3787|M.abscessus_ATCC_1997 MARTDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPLVRAVG
MSMEG_1481|M.smegmatis_MC2_155 MARTDTDSWDLASSVGATATMVAAARAIASTEPNALIDDPYAADLVRKVG
TH_2706|M.thermoresistible__bu MARSESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPLVRAVG
MLBr_02640|M.leprae_Br4923 -MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTG
*: * ** :.**.**.**** ** : ** **:* ** ..
MMAR_4850|M.marinum_M I-DVYTRLVNGQIPVDVESGFDPA-----RMAEAMACRTRFYDQFFVEAT
MUL_0450|M.ulcerans_Agy99 I-DVYTRLVNGQIPVDVESGFDPA-----RMPEAMACRTRFYDQFFVDAT
Mb0853|M.bovis_AF2122/97 M-DVYTRLVDWQIPVEGDSEFDPQ-----RMATGMACRTRFFDQFFLDAT
Rv0830|M.tuberculosis_H37Rv M-DVYTRLVDWQIPVEGDSEFDPQ-----RMATGMACRTRFFDQFFLDAT
MAV_0778|M.avium_104 I-DVYVRLVDGEIQP-GTSEFDPH-----RMAKGMACRTRFYDDFFLDAA
Mflv_5025|M.gilvum_PYR-GCK L-DFFTRMLDGELDLSVFPDSSPE--RAQAMIDGMAVRTRFFDDCCLAAA
Mvan_1344|M.vanbaalenii_PYR-1 L-SFFTKMLDGELDLSQFADGSPE--RVQAMIDGMAVRTRFFDDCCGTST
MAB_3787|M.abscessus_ATCC_1997 I-EYFTKLASGAFDPEQMAGLVQLGITADGMANGMASRTWYYDTAFESST
MSMEG_1481|M.smegmatis_MC2_155 L-EFFTKLVDGDIALDGD---DAAAAG--LMVSMMAVRTRFFDDFFCDAA
TH_2706|M.thermoresistible__bu V-EFFTRLVDGDLELPADTAEERAAAQ--VLTEVMAVRTRFFDDFFTDAT
MLBr_02640|M.leprae_Br4923 AGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAV
: : . : : * ** ::* :.
MMAR_4850|M.marinum_M RSGISQVVILASGLDARAYRLDWPAGTVVYEVDMPEVIEFKTLTLADLGA
MUL_0450|M.ulcerans_Agy99 RSGISQVVILASGLDARAYRLGWPAGTVVHEVDMPQVIEFKTLTLADLGA
Mb0853|M.bovis_AF2122/97 HSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGA
Rv0830|M.tuberculosis_H37Rv HSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGA
MAV_0778|M.avium_104 RAGVGQAVILASGLDARAYRLPWPAGTVVYEVDMPDVIEFKTLTLADLGA
Mflv_5025|M.gilvum_PYR-GCK SAGVRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTLRNLGA
Mvan_1344|M.vanbaalenii_PYR-1 TAGITQVVILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTLAGLGA
MAB_3787|M.abscessus_ATCC_1997 AAGVRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTLAELGA
MSMEG_1481|M.smegmatis_MC2_155 GAGIRQSVILAAGLDSRAYRLGWPAGTVVYEIDQPRVIEAKTAAMAEIGA
TH_2706|M.thermoresistible__bu RVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTLAELGA
MLBr_02640|M.leprae_Br4923 IDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGV
* * ****:***:*:*** ** *: *:*:* * *: *: :: *.
MMAR_4850|M.marinum_M EPTAERRTVAVDLRDDWAAALQAAGFDKDVPSAWSAEGLLVYLPDDAQDA
MUL_0450|M.ulcerans_Agy99 KPTAERRTVAVDLRDDWAAVLQAAGFDKDVPSAWSAEGLLVYLPDDAQGA
Mb0853|M.bovis_AF2122/97 EPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDA
Rv0830|M.tuberculosis_H37Rv EPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDA
MAV_0778|M.avium_104 QPTAQRRTVAIDLRDDWAAALREEGFDTQAPAAWSAEGLLVYLPEQAQDA
Mflv_5025|M.gilvum_PYR-GCK EPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPPEAQDA
Mvan_1344|M.vanbaalenii_PYR-1 HPTATHRPVPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPPEAQDQ
MAB_3787|M.abscessus_ATCC_1997 SPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGLLIYLPPEAQDR
MSMEG_1481|M.smegmatis_MC2_155 SPTAERRTVAVDLRDDWPAALRAAGFDAATPTAWIAEGLLVYLPPEAQDR
TH_2706|M.thermoresistible__bu PPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEGLLRYLPPDAQDR
MLBr_02640|M.leprae_Br4923 TPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDG
*:: :* *.:***:**...* *** :.* ***** *** **.
MMAR_4850|M.marinum_M LFDNITALSATGSRLAFEFVPDTAVFNDERWRSHHARMSELG---FEIDF
MUL_0450|M.ulcerans_Agy99 LFDNVTALSATGSRLAFEFVPDTAVFNDERWRSHHARMSELG---FEIDF
Mb0853|M.bovis_AF2122/97 LFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELG---FDIDL
Rv0830|M.tuberculosis_H37Rv LFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELG---FDIDL
MAV_0778|M.avium_104 LFDNITALSAPGSRLAFDFVPDTAVFADPRWRAHHERMSELG---FEVDF
Mflv_5025|M.gilvum_PYR-GCK LFDTVTALSAPGSTLATEYVPGIVDFDGAKARALSEPLREHG---LDIDM
Mvan_1344|M.vanbaalenii_PYR-1 LFDRITALSAPGSTIATEYAPGIIDFDDEKARAMSAPMREMG---LDIDM
MAB_3787|M.abscessus_ATCC_1997 LFASITELSAPGSRLVCEQVPGLETADFSKARELTRQFAGET---LDLDL
MSMEG_1481|M.smegmatis_MC2_155 LFDNITALSARGSRLATEYHPDITSTLRGRGQAMSERWRDHG---FDVDL
TH_2706|M.thermoresistible__bu LFDHITDLSAPGSRLATEDHPGPGAGLGEKADELGRRWREHG---FEVQL
MLBr_02640|M.leprae_Br4923 LFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALGFEQAVDV
** : *** ** :. : * : ::.
MMAR_4850|M.marinum_M NDLVYHGQ-RSHVIDHLARDGWQSASHTAKELHAANGFDYPDD-DIAAVF
MUL_0450|M.ulcerans_Agy99 NDLVYHGQ-RSHVIDHLARDGWQSASHTAKELHAANGLDYPDD-DIAAVF
Mb0853|M.bovis_AF2122/97 NELVYHGQ-RGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDD-ELATAF
Rv0830|M.tuberculosis_H37Rv NELVYHGQ-RGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDD-ELATAF
MAV_0778|M.avium_104 NDLVYHGE-RSHIVDHLSGRGWRVTSRTIAELHAANGFAYAAD-DVAAAF
Mflv_5025|M.gilvum_PYR-GCK PSLVYTGA-RTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADGTDPL
Mvan_1344|M.vanbaalenii_PYR-1 PSLVYAGT-RSHVMDYLAGQGWEVTGVPRRELFTRYGRPLPPEAGDTDPL
MAB_3787|M.abscessus_ATCC_1997 ESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN-LDPPNPLLRSIF
MSMEG_1481|M.smegmatis_MC2_155 SDLWYGGD-RNAADEYLAGHGWQVSTRPRPEVFAAYGRTFPDLTLTGDDN
TH_2706|M.thermoresistible__bu SELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYGREFPDSAAL----
MLBr_02640|M.leprae_Br4923 QELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDKD
.* : * : * ** : .
MMAR_4850|M.marinum_M ADITYTSAVLGR---------
MUL_0450|M.ulcerans_Agy99 ADITYTSAVLGR---------
Mb0853|M.bovis_AF2122/97 ADLTYSSATLMR---------
Rv0830|M.tuberculosis_H37Rv ADLTYSSATLMR---------
MAV_0778|M.avium_104 ADVTYSSAVLGG---------
Mflv_5025|M.gilvum_PYR-GCK GEIVYVSATLAADA-------
Mvan_1344|M.vanbaalenii_PYR-1 GEIVYVSAHRPQ---------
MAB_3787|M.abscessus_ATCC_1997 PNIVYVDATLG----------
MSMEG_1481|M.smegmatis_MC2_155 AAMRQSVAITATRS-------
TH_2706|M.thermoresistible__bu AAMRDSSAVTAVRPVVRAGMR
MLBr_02640|M.leprae_Br4923 AFAEFVTAHRL----------
*