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TKRAATTAVVMMFLALVGCAPKQSISNPPSTPSQLPPNEVSGIDIPPGRIDEAVAKVDGLVAELMKSTGI PGMAVAIVHGGKTLYAKGFGVRDVSKGDGQDNKVDTDTVFQLASMSKPIGATVVAHEVSTNVVSWDTPVV SKLPEFALSDPYVTDHATIADLYSHRSGLPDHAGDALEDLGYDTTQVLERLKYLPLDPFRISYAYTNFGV TAAADAVAAAAGKAWPDLSEEVLYRPLGMTSTSSRFADFLARPNHAVNHIKVGDRWEARFQRDPDAQTPA GGVSSSLNDMAHWLTMVLANGEYNGQQIVSPEALLPAITPQVISSAARSPKARAGFYGHGFTVSVSSAGR TQYGHSGAFGLGAATNFVVLPSEDIAIVALTNAAPYGIPEALTAQFMDLVQYGEVREDWTNLYRQQMSPI NTPEGSLVGKQPPVNPEPARPPSDYVGVYANDYWGPATVTERDGQLQLSMGPKNQTFDLTHWDGDTFTFA LSTENALPGSISKATFAGDTLNLEYFDSNKLGTFTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4623 | - | - | 100% (527) | penicillin binding protein |
| M. marinum M | MMAR_2827 | - | 3e-13 | 27.19% (228) | lipoprotein |
| M. marinum M | MMAR_3399 | - | 3e-12 | 25.51% (247) | hypothetical protein MMAR_3399 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0931 | - | 0.0 | 77.71% (516) | hypothetical protein Mb0931 |
| M. gilvum PYR-GCK | Mflv_1757 | - | 1e-175 | 56.39% (532) | beta-lactamase |
| M. tuberculosis H37Rv | Rv0907 | - | 0.0 | 78.39% (509) | hypothetical protein Rv0907 |
| M. leprae Br4923 | MLBr_01782 | - | 6e-06 | 27.17% (173) | hypothetical protein MLBr_01782 |
| M. abscessus ATCC 19977 | MAB_2833 | - | 7e-12 | 23.04% (369) | beta-lactamase |
| M. avium 104 | MAV_1030 | - | 0.0 | 71.51% (530) | penicillin-binding protein 4 |
| M. smegmatis MC2 155 | MSMEG_5637 | - | 0.0 | 62.50% (528) | penicillin-binding protein 4 |
| M. thermoresistible (build 8) | TH_0096 | - | 0.0 | 60.72% (527) | penicillin-binding protein 4 |
| M. ulcerans Agy99 | MUL_1772 | - | 2e-10 | 22.86% (315) | beta-lactamase |
| M. vanbaalenii PYR-1 | Mvan_4990 | - | 1e-178 | 58.08% (532) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0931|M.bovis_AF2122/97 ---------MMLLT----------------LTGCGSTHQALGPPSGL---
Rv0907|M.tuberculosis_H37Rv ---------MATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGL---
MMAR_4623|M.marinum_M ---------MTKRAAT-----TAVVMMFLALVGCAPKQSISNPPSTP---
MAV_1030|M.avium_104 ---------MSKRAAV-------LTAVLLGLTGCGSAQQPAGAPPRP---
Mflv_1757|M.gilvum_PYR-GCK ---MK----SRVGAVA-------LVMAVALLAGCAAESTEPAASSTPAPG
Mvan_4990|M.vanbaalenii_PYR-1 ---MK----PRARVAA-------LALTAALLAGCGTEGAEPAASSTPAPS
MSMEG_5637|M.smegmatis_MC2_155 MYSMRRSVFARAVGSA-------LVVGLAVSGCAGGDDTADAQRSAQPSQ
TH_0096|M.thermoresistible__bu ---------VLKRFAA-------VLTALVLLAGCRSGDDASTAHPS----
MAB_2833|M.abscessus_ATCC_1997 ------------------------------MAEP----------------
MUL_1772|M.ulcerans_Agy99 ----------------------------MGVARPRWRGPRAAWFAGARKP
MLBr_01782|M.leprae_Br4923 --------------------------------------------------
Mb0931|M.bovis_AF2122/97 --PDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
Rv0907|M.tuberculosis_H37Rv --PDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
MMAR_4623|M.marinum_M --SQLPPNEVSGIDIPPGRIDEAVAKVDGLVAELMKSTGIPGMAVAIVHG
MAV_1030|M.avium_104 --SDVSPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAVAIVHG
Mflv_1757|M.gilvum_PYR-GCK PLSDVPPPLVPAMPLPENAVANAVAKLDGLAEDLMSTSGVPGMAVAVVHQ
Mvan_4990|M.vanbaalenii_PYR-1 PASDVPPPLVPAMPLPENAVADAVAKLDGLAEDLMSKSGIPGMAVAVVHG
MSMEG_5637|M.smegmatis_MC2_155 TFADEPPPLVPAMALPENAVENAVAKLDGIAEDLMRSSGIPGMAVAVVHG
TH_0096|M.thermoresistible__bu --SDLPPPLVAAVDLPADAVANAVARLDGLAADLLEQSGIPGLAVAVVHG
MAB_2833|M.abscessus_ATCC_1997 ----------------DSTFDAALAPIR----AAIDDRILAGAVTLVWQG
MUL_1772|M.ulcerans_Agy99 SDGRRLTRRPPAANLNPVNLDANQADIR----EVCDAGLLSGAVTVVWQH
MLBr_01782|M.leprae_Br4923 ----------------------------MVALDALDDWPVPTTAAAVVGP
:. .. :
Mb0931|M.bovis_AF2122/97 GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTD
Rv0907|M.tuberculosis_H37Rv GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTD
MMAR_4623|M.marinum_M GKTLYAKGFGVRDVSKGDGQDNKVDTDTVFQLASMSKPIGATVVAHEVST
MAV_1030|M.avium_104 GKVLYAKGFGVKDVTSGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSD
Mflv_1757|M.gilvum_PYR-GCK GKTVYAKGFGVKNNTQSDSPENRVDADTVFQLASLSKPLSATVVAALVGQ
Mvan_4990|M.vanbaalenii_PYR-1 GKAVYAKGFGVRNNTMSDEPHNEVDADTVFQLASLSKPLSATAVAALVGQ
MSMEG_5637|M.smegmatis_MC2_155 GKTVYAKGFGVRDVRNGDVESNRVDPDTVFQLASLSKPIAATVVAHQVGT
TH_0096|M.thermoresistible__bu GKTVYAKGFGVKDIRTGDP----VGADTVFQLASLSKPIGATVVAHQVGT
MAB_2833|M.abscessus_ATCC_1997 GQLRHLGATGYRDIDAGLS----MAENTIFRIASMTKPIISAATMNLVDD
MUL_1772|M.ulcerans_Agy99 GEVLQVNEIGYRDVEAGLP----MQRDTLFRIASMTKPVTVAAAMSMVDE
MLBr_01782|M.leprae_Br4923 TGVLAARG----------------DTEQVFPLASVTKPLVARAVQIAIEE
: :* :**::*.: .. :
Mb0931|M.bovis_AF2122/97 NVVTWDTPVVSKLPWF----ALRDP--------YVTGQVTIADLYSHRSG
Rv0907|M.tuberculosis_H37Rv NVVTWDTPVVSKLPWF----ALRDP--------YVTGQVTIADLYSHRSG
MMAR_4623|M.marinum_M NVVSWDTPVVSKLPEF----ALSDP--------YVTDHATIADLYSHRSG
MAV_1030|M.avium_104 HVVGWDTPVVSTLPWF----ALGDP--------YVTGHVTVGDLYSHRSG
Mflv_1757|M.gilvum_PYR-GCK DQVGWDTPVVSRLPWF----ALSDP--------TTTQMVTVGDMFSHRSG
Mvan_4990|M.vanbaalenii_PYR-1 NQVSWDTPIVSRLPWF----ALSDP--------AVTQMVTVGDMFSHRSG
MSMEG_5637|M.smegmatis_MC2_155 GAIGWDTPVVEHLPWF----ALSDP--------VTTRMVTVGDLFAHRSG
TH_0096|M.thermoresistible__bu GAISWDTPVISRLPWF----RLSDP--------VVTERVTIGDMYAHRSG
MAB_2833|M.abscessus_ATCC_1997 GTIRLSDPITTWLPEFSDMRVLKNPEGPLDDTFRAPRLITVEDLLTHRSG
MUL_1772|M.ulcerans_Agy99 GKIALRDPITRWAPELRDIRVLDDPHGPLDRTHPTRRPILIEDLLTHTSG
MLBr_01782|M.leprae_Br4923 GVVDLDTVAGP-------------------------PGSTIRHLLAHASG
: : .: :* **
Mb0931|M.bovis_AF2122/97 LP---DHAGDLLEDLG-------YDRRQVLQRLKYLPLAPFRISYAYTNF
Rv0907|M.tuberculosis_H37Rv LP---DHAGDLLEDLG-------YDRRQVLQRLKYLPLAPFRISYAYTNF
MMAR_4623|M.marinum_M LP---DHAGDALEDLG-------YDTTQVLERLKYLPLDPFRISYAYTNF
MAV_1030|M.avium_104 LP---DHAGDKLEDLG-------YGRRQICERLRLLPLRPFRNSYAYTNY
Mflv_1757|M.gilvum_PYR-GCK LP---DHAGDQLEDLG-------YDRRQVLDRLRQLPLAQFRTSYAYTNF
Mvan_4990|M.vanbaalenii_PYR-1 LP---DHAGDQLEDLG-------YDRRQVLERLRQLPLDQFRTSYAYTNF
MSMEG_5637|M.smegmatis_MC2_155 LP---DHAGDQLEDLG-------YDRRYILEHLRALPLDPFRNSYAYTNF
TH_0096|M.thermoresistible__bu LP---DHAGDLLEDLG-------YDRRQVLEKLAQLPLAPFRISYAYTNF
MAB_2833|M.abscessus_ATCC_1997 LTYDFISTGPIAKAYHPLHTAAFREPDEWLAAIAALPLVYPPGERFHYSH
MUL_1772|M.ulcerans_Agy99 LAYSFSVSGDISRAYMRLPFG--HGSDAWLAELAALPLVHQPGERVTYSH
MLBr_01782|M.leprae_Br4923 LA-----------------------------MHSKYVMAPPGTRRIYSNY
*. : ..
Mb0931|M.bovis_AF2122/97 GVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVN
Rv0907|M.tuberculosis_H37Rv GVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVN
MMAR_4623|M.marinum_M GVTAAADAVAAAAGKAWPDLSEEVLYRPLGMTSTSSRFADFLARPNHAVN
MAV_1030|M.avium_104 GITAAAEAVAAAAGKTWEELSDEVLYRPLGMTSTSSRFADFLARPNRAVN
Mflv_1757|M.gilvum_PYR-GCK GLTAGAEAVATGAGKSWEDLAADTLLRPLGMGVTSYRFEDYASRRDRAVG
Mvan_4990|M.vanbaalenii_PYR-1 GLTAGAEAVATGAGKSWEDLAADTLLRPLGMGATSYRFSDYESRRDRAVG
MSMEG_5637|M.smegmatis_MC2_155 GLTAAAEAVAAAAGRSWEDLARDVLYRPLGMDSTSSRFADYEATQNRAVG
TH_0096|M.thermoresistible__bu GXTAAAEAVAADAGMPWEELSGRVLYEPLGMASTSSRFADYQARADRAVG
MAB_2833|M.abscessus_ATCC_1997 STDVLGLLIARAAGLPLNTLLRQRILDPLGMNDTDFFVPEHKAARLARLY
MUL_1772|M.ulcerans_Agy99 AIDLLGVIMSRIDDKPFYQVLDERILGPAGMTDTGFFVSTQAQRRAATMY
MLBr_01782|M.leprae_Br4923 GFRVLAETVQREAGIGFSRYLTEAVLEPLAMTATKLEDGTWAAG------
. . : . : * .* *
Mb0931|M.bovis_AF2122/97 HVKVADRWEARYQRDPDAQS--------PAGGVSSSLNDMTHWLAMVLAD
Rv0907|M.tuberculosis_H37Rv HVKVADRWEARYQRDPDAQS--------PAGGVSSSLNDMTHWLAMVLAD
MMAR_4623|M.marinum_M HIKVGDRWEARFQRDPDAQT--------PAGGVSSSLNDMAHWLTMVLAN
MAV_1030|M.avium_104 HIKIGDSWQARFQRNPDAQS--------PAGGVSSSVRDMARWLMMLLDN
Mflv_1757|M.gilvum_PYR-GCK HIRIDDGYQPRYVRDAQAQS--------PAGGASSSVNDMTRWMAMVLAE
Mvan_4990|M.vanbaalenii_PYR-1 HIRIDGGYQPRFVRDAQAQS--------PAGGASSSVNDMTRWMAMVLAD
MSMEG_5637|M.smegmatis_MC2_155 HIRVDGRYEPQYVRNADAQT--------PAGGVSASVDDMTRWLAMVLGD
TH_0096|M.thermoresistible__bu HIHVDGGYQPFYLRDPDAES--------PAGGVSSSVNDVARWLAMVLGD
MAB_2833|M.abscessus_ATCC_1997 GLGDDDTIVAADSGYLTAMPTSAPALCRGGGALASTAHDYLTFARALLGG
MUL_1772|M.ulcerans_Agy99 RLDELDQLRHDVMGPPHVRP---PSFCNAGGGLWSTADDYLRFVRLLLGD
MLBr_01782|M.leprae_Br4923 ------------------------------FGATSTVADLAAFANDLLRP
. :: * : :*
Mb0931|M.bovis_AF2122/97 GVYNGRRITSPEALLLVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGR
Rv0907|M.tuberculosis_H37Rv GVYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGR
MMAR_4623|M.marinum_M GEYNGQQIVSPEALLPAITPQVISSAARSPKARAGFYGHGFTVSVSSAGR
MAV_1030|M.avium_104 GTHDGQHIASPEALLPALSPQVVSAPATTPKARTGFYGYGFNTSVDASGR
Mflv_1757|M.gilvum_PYR-GCK GRHDGNALIDPQALLPAISPQVTSAPPTEPAMRPGFYGYGFNVGTTSAAR
Mvan_4990|M.vanbaalenii_PYR-1 GRHDGNQLIDPTALLPAITPQVTSSRGSEPAMRSGFYGYGFNVGTTSAAR
MSMEG_5637|M.smegmatis_MC2_155 GVFEGERIVEESTLLPAITPQVVSDRASQPAMRSGFYGYGFNVGTTSAAR
TH_0096|M.thermoresistible__bu GSFEGRRIVDPDALLPALTPQIVSSPATEPAMRSGFYGYGFNVGITSAAR
MAB_2833|M.abscessus_ATCC_1997 GQADGVRILSPESTQALRTNRLTPAQR-----RLPSFGIPYWTGRG----
MUL_1772|M.ulcerans_Agy99 GTIDGVRVLSPESVRLMRTDRLSDEHK-----RHNFLGAPFWVGRG----
MLBr_01782|M.leprae_Br4923 ATVSAQIHAEATSVQFPDLDGVLPGHGVQ---RPNDWGLGYEIKNS----
. .. . : : * * :
Mb0931|M.bovis_AF2122/97 TEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLV
Rv0907|M.tuberculosis_H37Rv TEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLV
MMAR_4623|M.marinum_M TQYGHSGAFGLGAATNFVVLPSEDIAIVALTNAAPYGIPEALTAQFMDLV
MAV_1030|M.avium_104 TEYSHSGAFDLGAATNFVVLPSEDLAIIALTNAAPYGIPETLTAEFMDLV
Mflv_1757|M.gilvum_PYR-GCK TQLSHSGAFELGAATNVLFLPSADVAIIALTNATPTGVPETLTAQFADLV
Mvan_4990|M.vanbaalenii_PYR-1 TQLSHSGAFELGAATNVLFLPSADVAIVALTNATPTGIPETLTAQFADLV
MSMEG_5637|M.smegmatis_MC2_155 TQLSHSGAFELGAATNFVILPSADVGIVALTNGTPAGIPETLTAEFADLV
TH_0096|M.thermoresistible__bu TELSHSGAFELGTGTNFVILPSADAGIVALTNATPSGVAEALTAQFADLV
MAB_2833|M.abscessus_ATCC_1997 ----------FGLGLSVVMDPNE-AALFGPGGTGTFGWPGAFGTWWH---
MUL_1772|M.ulcerans_Agy99 ----------FGLNLSVVTDPVQSTPLFGPGGLGTFSWPGAYGTWWQ---
MLBr_01782|M.leprae_Br4923 ------------------KLPHWTGTLNSARTYGHFGQSGGF--------
* : . . .
Mb0931|M.bovis_AF2122/97 QYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYA
Rv0907|M.tuberculosis_H37Rv QYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYA
MMAR_4623|M.marinum_M QYGEVREDWTNLYRQQMSPINTPEGSLVGKQPPVNPEPARPPSDYVGVYA
MAV_1030|M.avium_104 QYGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSAPAPARPLRDYTGVYA
Mflv_1757|M.gilvum_PYR-GCK QFGEIRQDWAALYGKAFADMDKPVGSLVGQQRHVNAQTHGPLDSYTGVYG
Mvan_4990|M.vanbaalenii_PYR-1 QFGEIRQDWYALYAKAFEDMDKPVGSLVGQQRPANAQAHGPLAAYTGVYR
MSMEG_5637|M.smegmatis_MC2_155 QFGEVRQDWRKLYADAFASMDGPEGELVGKKPPAVPAPARPLPDYVGVYR
TH_0096|M.thermoresistible__bu QFGEIREDWYRLYRELMAPLEQPQGSLVGRPRPADPAPPAPLSTYVGTYH
MAB_2833|M.abscessus_ATCC_1997 --ADPKADAILMFLPQWR------------MPELDPKAALARTST---IR
MUL_1772|M.ulcerans_Agy99 --ADPGADLILLYLIQH-------------CPDLSVNAAAAVAGNPGLAK
MLBr_01782|M.leprae_Br4923 ---------------------------IWADPEAELALVVLTDRDFGEWA
Mb0931|M.bovis_AF2122/97 NDYWGPATVTYHDGQLRLSLGPKN--------QTFDLTHWDGDTFTFTLS
Rv0907|M.tuberculosis_H37Rv NDYWGPATVTYHDGQLRLSLGPKN--------QTFDLTHWDGDTFTFTLS
MMAR_4623|M.marinum_M NDYWGPATVTERDGQLQLSMGPKN--------QTFDLTHWDGDTFTFALS
MAV_1030|M.avium_104 NDYWGPAVITEHDGALQLTMGPQH--------RTATLTHWDGDTFTFPLT
Mflv_1757|M.gilvum_PYR-GCK NDYWGPATVTERDGRLQLALGPR---------GVFELDAWDGNVFVFPVS
Mvan_4990|M.vanbaalenii_PYR-1 NDYWGPATVTERDGHLELALGPR---------GVFKLQPWDGNVFTFPVS
MSMEG_5637|M.smegmatis_MC2_155 NDYWGPATVTEQDGALQLALGPK---------FKARLTHWDGDVFTFRFV
TH_0096|M.thermoresistible__bu NDYWGPARVTERDGKLVLDMGPPDARPQPGAPDEFPLTHWDGNVFTFTLV
MAB_2833|M.abscessus_ATCC_1997 LQLLHVQFGQAVYAAL----------------------------------
MUL_1772|M.ulcerans_Agy99 LRTAQPRFVRRTYRALGL--------------------------------
MLBr_01782|M.leprae_Br4923 LQLWPAISDAVISEYAR---------------------------------
Mb0931|M.bovis_AF2122/97 TENALPGSISKATFAG---DTLNLEYYDADKLGTFTR
Rv0907|M.tuberculosis_H37Rv TENALPGSISKATFAG---DTLNLEYYDADKLGTFTR
MMAR_4623|M.marinum_M TENALPGSISKATFAG---DTLNLEYFDSNKLGTFTR
MAV_1030|M.avium_104 GENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR
Mflv_1757|M.gilvum_PYR-GCK SENAPPGTVSAATFDG---GALTLEYFDQEGNGVFVR
Mvan_4990|M.vanbaalenii_PYR-1 SENAPPGTVSAATFDA---GSLTLEYFDDEGKGVFTR
MSMEG_5637|M.smegmatis_MC2_155 SENAPPGTISKATFAG---DKLTLEYFDEDGTGTFTR
TH_0096|M.thermoresistible__bu TENAPPGTISKATFDG---DRLTLEYYDDVHDGVFVK
MAB_2833|M.abscessus_ATCC_1997 -------------------------------------
MUL_1772|M.ulcerans_Agy99 -------------------------------------
MLBr_01782|M.leprae_Br4923 -------------------------------------