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VMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRD PYVTGQVTIADLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAA AGQSWEDLSDEVLYRPLGMGSTSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDM THWLAMVLADGVYNGRRITSPEALLLVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFG LGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPLNELAGSLVGK QSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTHWDGDTFTFTLSTENALPGS ISKATFAGDTLNLEYYDADKLGTFTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0931 | - | - | 100% (516) | hypothetical protein Mb0931 |
| M. bovis AF2122 / 97 | Mb1759c | - | 8e-25 | 28.08% (349) | penicillin-binding protein |
| M. bovis AF2122 / 97 | Mb1957 | - | 1e-13 | 27.62% (239) | lipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1757 | - | 1e-176 | 59.50% (516) | beta-lactamase |
| M. tuberculosis H37Rv | Rv0907 | - | 0.0 | 99.41% (511) | hypothetical protein Rv0907 |
| M. leprae Br4923 | MLBr_01782 | - | 1e-05 | 24.00% (300) | hypothetical protein MLBr_01782 |
| M. abscessus ATCC 19977 | MAB_0330 | - | 1e-12 | 26.02% (342) | Beta-lactamase |
| M. marinum M | MMAR_4623 | - | 0.0 | 77.71% (516) | penicillin binding protein |
| M. avium 104 | MAV_1030 | - | 0.0 | 72.97% (518) | penicillin-binding protein 4 |
| M. smegmatis MC2 155 | MSMEG_5637 | - | 0.0 | 62.07% (522) | penicillin-binding protein 4 |
| M. thermoresistible (build 8) | TH_0096 | - | 0.0 | 61.07% (524) | penicillin-binding protein 4 |
| M. ulcerans Agy99 | MUL_1772 | - | 2e-11 | 22.35% (358) | beta-lactamase |
| M. vanbaalenii PYR-1 | Mvan_4990 | - | 1e-175 | 59.11% (516) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0931|M.bovis_AF2122/97 ---------MMLLT----------------LTGCGSTHQALGPPSGL---
Rv0907|M.tuberculosis_H37Rv ---------MATICGHDQTSGNGRHGDVADVNGCGSTHQALGPPSGL---
MMAR_4623|M.marinum_M ---------MTKRAAT-----TAVVMMFLALVGCAPKQSISNPPSTP---
MAV_1030|M.avium_104 ---------MSKRAAV-------LTAVLLGLTGCGSAQQPAGAPPRP---
Mflv_1757|M.gilvum_PYR-GCK ---MK----SRVGAVA-------LVMAVALLAGCAAESTEPAASSTPAPG
Mvan_4990|M.vanbaalenii_PYR-1 ---MK----PRARVAA-------LALTAALLAGCGTEGAEPAASSTPAPS
MSMEG_5637|M.smegmatis_MC2_155 MYSMRRSVFARAVGSA-------LVVGLAVSGCAGGDDTADAQRSAQPSQ
TH_0096|M.thermoresistible__bu ---------VLKRFAA-------VLTALVLLAGCRSGDDASTAHPS----
MLBr_01782|M.leprae_Br4923 --------------------------------------------------
MAB_0330|M.abscessus_ATCC_1997 --------------------------MPELSTRCFDESSLMRRILAVVLT
MUL_1772|M.ulcerans_Agy99 -------------------------MGVARPRWRGPRAAWFAGARKP---
Mb0931|M.bovis_AF2122/97 --PDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
Rv0907|M.tuberculosis_H37Rv --PDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
MMAR_4623|M.marinum_M --SQLPPNEVSGIDIPPGRIDEAVAKVDGLVAELMKSTGIPGMAVAIVHG
MAV_1030|M.avium_104 --SDVSPNQVSALAIPAGRIDEAVAKVDGLVADLMRSSGIPGMAVAIVHG
Mflv_1757|M.gilvum_PYR-GCK PLSDVPPPLVPAMPLPENAVANAVAKLDGLAEDLMSTSGVPGMAVAVVHQ
Mvan_4990|M.vanbaalenii_PYR-1 PASDVPPPLVPAMPLPENAVADAVAKLDGLAEDLMSKSGIPGMAVAVVHG
MSMEG_5637|M.smegmatis_MC2_155 TFADEPPPLVPAMALPENAVENAVAKLDGIAEDLMRSSGIPGMAVAVVHG
TH_0096|M.thermoresistible__bu --SDLPPPLVAAVDLPADAVANAVARLDGLAADLLEQSGIPGLAVAVVHG
MLBr_01782|M.leprae_Br4923 ----------------------------MVALDALDDWPVPTTAAAVVGP
MAB_0330|M.abscessus_ATCC_1997 IALLVSACGKHSAIVVAELDPQTTAKLDSAINEILTSAAVPGAIVGVWGP
MUL_1772|M.ulcerans_Agy99 ----SDGRRLTRRPPAANLNPVNLDANQADIREVCDAGLLSGAVTVVWQH
: :. . :
Mb0931|M.bovis_AF2122/97 GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTD
Rv0907|M.tuberculosis_H37Rv GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTD
MMAR_4623|M.marinum_M GKTLYAKGFGVRDVSKGDGQDNKVDTDTVFQLASMSKPIGATVVAHEVST
MAV_1030|M.avium_104 GKVLYAKGFGVKDVTSGQGRDNAVDTDTVFQLASVSKSVGATVVAHEVSD
Mflv_1757|M.gilvum_PYR-GCK GKTVYAKGFGVKNNTQSDSPENRVDADTVFQLASLSKPLSATVVAALVGQ
Mvan_4990|M.vanbaalenii_PYR-1 GKAVYAKGFGVRNNTMSDEPHNEVDADTVFQLASLSKPLSATAVAALVGQ
MSMEG_5637|M.smegmatis_MC2_155 GKTVYAKGFGVRDVRNGDVESNRVDPDTVFQLASLSKPIAATVVAHQVGT
TH_0096|M.thermoresistible__bu GKTVYAKGFGVKDIRTGDP----VGADTVFQLASLSKPIGATVVAHQVGT
MLBr_01782|M.leprae_Br4923 TGVLAARG----------------DTEQVFPLASVTKPLVARAVQIAIEE
MAB_0330|M.abscessus_ATCC_1997 -KGQYVRTFGVANTATRAP----LRPDFYHRIGSVTKTFTVTAVLQLVDE
MUL_1772|M.ulcerans_Agy99 GEVLQVNEIGYRDVEAGLP----MQRDTLFRIASMTKPVTVAAAMSMVDE
.. : . :.*::*.. . .. :
Mb0931|M.bovis_AF2122/97 NVVTWDTPVVSKLPWF------------ALRDPYVTGQVTIADLYSHRSG
Rv0907|M.tuberculosis_H37Rv NVVTWDTPVVSKLPWF------------ALRDPYVTGQVTIADLYSHRSG
MMAR_4623|M.marinum_M NVVSWDTPVVSKLPEF------------ALSDPYVTDHATIADLYSHRSG
MAV_1030|M.avium_104 HVVGWDTPVVSTLPWF------------ALGDPYVTGHVTVGDLYSHRSG
Mflv_1757|M.gilvum_PYR-GCK DQVGWDTPVVSRLPWF------------ALSDPTTTQMVTVGDMFSHRSG
Mvan_4990|M.vanbaalenii_PYR-1 NQVSWDTPIVSRLPWF------------ALSDPAVTQMVTVGDMFSHRSG
MSMEG_5637|M.smegmatis_MC2_155 GAIGWDTPVVEHLPWF------------ALSDPVTTRMVTVGDLFAHRSG
TH_0096|M.thermoresistible__bu GAISWDTPVISRLPWF------------RLSDPVVTERVTIGDMYAHRSG
MLBr_01782|M.leprae_Br4923 GVVDLDT----------------------VAGPPGS---TIRHLLAHASG
MAB_0330|M.abscessus_ATCC_1997 GKVELDDPIAKYVDKV------------PNGNKITLRELARMQSGLFNYS
MUL_1772|M.ulcerans_Agy99 GKIALRDPITRWAPELRDIRVLDDPHGPLDRTHPTRRPILIEDLLTHTSG
: . . .
Mb0931|M.bovis_AF2122/97 LPDHAGDLLEDL--------GYDRRQVLQRLKYLPLAPF----RISYAYT
Rv0907|M.tuberculosis_H37Rv LPDHAGDLLEDL--------GYDRRQVLQRLKYLPLAPF----RISYAYT
MMAR_4623|M.marinum_M LPDHAGDALEDL--------GYDTTQVLERLKYLPLDPF----RISYAYT
MAV_1030|M.avium_104 LPDHAGDKLEDL--------GYGRRQICERLRLLPLRPF----RNSYAYT
Mflv_1757|M.gilvum_PYR-GCK LPDHAGDQLEDL--------GYDRRQVLDRLRQLPLAQF----RTSYAYT
Mvan_4990|M.vanbaalenii_PYR-1 LPDHAGDQLEDL--------GYDRRQVLERLRQLPLDQF----RTSYAYT
MSMEG_5637|M.smegmatis_MC2_155 LPDHAGDQLEDL--------GYDRRYILEHLRALPLDPF----RNSYAYT
TH_0096|M.thermoresistible__bu LPDHAGDLLEDL--------GYDRRQVLEKLAQLPLAPF----RISYAYT
MLBr_01782|M.leprae_Br4923 LAMHSKYVMAPP--------GTRR-----------------------IYS
MAB_0330|M.abscessus_ATCC_1997 MSLAFSRDLEAD--------PRRQYSTHELLDYAFAQPSNFVPGQGYEYS
MUL_1772|M.ulcerans_Agy99 LAYSFSVSGDISRAYMRLPFGHGSDAWLAELAALPLVHQ----PGERVTY
:.
Mb0931|M.bovis_AF2122/97 NFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSS-RFTDFLARPNH
Rv0907|M.tuberculosis_H37Rv NFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGSTSS-RFTDFLARPNH
MMAR_4623|M.marinum_M NFGVTAAADAVAAAAGKAWPDLSEEVLYRPLGMTSTSS-RFADFLARPNH
MAV_1030|M.avium_104 NYGITAAAEAVAAAAGKTWEELSDEVLYRPLGMTSTSS-RFADFLARPNR
Mflv_1757|M.gilvum_PYR-GCK NFGLTAGAEAVATGAGKSWEDLAADTLLRPLGMGVTSY-RFEDYASRRDR
Mvan_4990|M.vanbaalenii_PYR-1 NFGLTAGAEAVATGAGKSWEDLAADTLLRPLGMGATSY-RFSDYESRRDR
MSMEG_5637|M.smegmatis_MC2_155 NFGLTAAAEAVAAAAGRSWEDLARDVLYRPLGMDSTSS-RFADYEATQNR
TH_0096|M.thermoresistible__bu NFGXTAAAEAVAADAGMPWEELSGRVLYEPLGMASTSS-RFADYQARADR
MLBr_01782|M.leprae_Br4923 NYGFRVLAETVQREAGIGFSRYLTEAVLEPLAMTATKL-EDGTWAAG---
MAB_0330|M.abscessus_ATCC_1997 NTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPETSAIADPHAR
MUL_1772|M.ulcerans_Agy99 SHAIDLLGVIMSRIDDKPFYQVLDERILGPAGMTDTGFFVSTQAQRRAAT
. . : . : * .* *
Mb0931|M.bovis_AF2122/97 AVNHVKVADR----WEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADG
Rv0907|M.tuberculosis_H37Rv AVNHVKVADR----WEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADG
MMAR_4623|M.marinum_M AVNHIKVGDR----WEARFQRDPDAQTPAGGVSSSLNDMAHWLTMVLANG
MAV_1030|M.avium_104 AVNHIKIGDS----WQARFQRNPDAQSPAGGVSSSVRDMARWLMMLLDNG
Mflv_1757|M.gilvum_PYR-GCK AVGHIRIDDG----YQPRYVRDAQAQSPAGGASSSVNDMTRWMAMVLAEG
Mvan_4990|M.vanbaalenii_PYR-1 AVGHIRIDGG----YQPRFVRDAQAQSPAGGASSSVNDMTRWMAMVLADG
MSMEG_5637|M.smegmatis_MC2_155 AVGHIRVDGR----YEPQYVRNADAQTPAGGVSASVDDMTRWLAMVLGDG
TH_0096|M.thermoresistible__bu AVGHIHVDGG----YQPFYLRDPDAESPAGGVSSSVNDVARWLAMVLGDG
MLBr_01782|M.leprae_Br4923 -----------------------------FGATSTVADLAAFANDLLRPA
MAB_0330|M.abscessus_ATCC_1997 GYTQLTPTGS----LVDSTDWNPSWASWAGAMISTLDDLRIWVPALATG-
MUL_1772|M.ulcerans_Agy99 MYRLDELDQLRHDVMGPPHVRPPSFCNAGGGLWSTADDYLRFVRLLLGDG
. :: * : :
Mb0931|M.bovis_AF2122/97 VYNGRRITSPEALLLVYTPQVISRHPVSPRARASFYG---YGFNVGVTSS
Rv0907|M.tuberculosis_H37Rv VYNGRRITSPEALLPVYTPQVISRHPVSPRARASFYG---YGFNVGVTSS
MMAR_4623|M.marinum_M EYNGQQIVSPEALLPAITPQVISSAARSPKARAGFYG---HGFTVSVSSA
MAV_1030|M.avium_104 THDGQHIASPEALLPALSPQVVSAPATTPKARTGFYG---YGFNTSVDAS
Mflv_1757|M.gilvum_PYR-GCK RHDGNALIDPQALLPAISPQVTSAPPTEPAMRPGFYG---YGFNVGTTSA
Mvan_4990|M.vanbaalenii_PYR-1 RHDGNQLIDPTALLPAITPQVTSSRGSEPAMRSGFYG---YGFNVGTTSA
MSMEG_5637|M.smegmatis_MC2_155 VFEGERIVEESTLLPAITPQVVSDRASQPAMRSGFYG---YGFNVGTTSA
TH_0096|M.thermoresistible__bu SFEGRRIVDPDALLPALTPQIVSSPATEPAMRSGFYG---YGFNVGITSA
MLBr_01782|M.leprae_Br4923 TVSAQIHAEATSVQFPDLDGVLPGHGVQ---RPNDWG---LGYEIKNSK-
MAB_0330|M.abscessus_ATCC_1997 -----VLLKPDSQQQRLQTVAMPPVPDDIRYGLGIFD---ARGWIGHSGS
MUL_1772|M.ulcerans_Agy99 TIDGVRVLSPESVRLMRTDRLSDEHKRHNFLGAPFWVGRGFGLNLSVVTD
. : :
Mb0931|M.bovis_AF2122/97 GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMD
Rv0907|M.tuberculosis_H37Rv GRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMD
MMAR_4623|M.marinum_M GRTQYGHSGAFGLGAATNFVVLPSEDIAIVALTNAAPYGIPEALTAQFMD
MAV_1030|M.avium_104 GRTEYSHSGAFDLGAATNFVVLPSEDLAIIALTNAAPYGIPETLTAEFMD
Mflv_1757|M.gilvum_PYR-GCK ARTQLSHSGAFELGAATNVLFLPSADVAIIALTNATPTGVPETLTAQFAD
Mvan_4990|M.vanbaalenii_PYR-1 ARTQLSHSGAFELGAATNVLFLPSADVAIVALTNATPTGIPETLTAQFAD
MSMEG_5637|M.smegmatis_MC2_155 ARTQLSHSGAFELGAATNFVILPSADVGIVALTNGTPAGIPETLTAEFAD
TH_0096|M.thermoresistible__bu ARTELSHSGAFELGTGTNFVILPSADAGIVALTNATPSGVAEALTAQFAD
MLBr_01782|M.leprae_Br4923 ---------------------LP-------------------HWTGTLNS
MAB_0330|M.abscessus_ATCC_1997 --------------------------------------------IPGYQT
MUL_1772|M.ulcerans_Agy99 PVQSTPLFGP--------------------------------GGLGTFSW
Mb0931|M.bovis_AF2122/97 LVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGV
Rv0907|M.tuberculosis_H37Rv LVQYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGV
MMAR_4623|M.marinum_M LVQYGEVREDWTNLYRQQMSPINTPEGSLVGKQPPVNPEPARPPSDYVGV
MAV_1030|M.avium_104 LVQYGQIREDWAALYRKAIGWLNNPLGSLVGKQPPSAPAPARPLRDYTGV
Mflv_1757|M.gilvum_PYR-GCK LVQFGEIRQDWAALYGKAFADMDKPVGSLVGQQRHVNAQTHGPLDSYTGV
Mvan_4990|M.vanbaalenii_PYR-1 LVQFGEIRQDWYALYAKAFEDMDKPVGSLVGQQRPANAQAHGPLAAYTGV
MSMEG_5637|M.smegmatis_MC2_155 LVQFGEVRQDWRKLYADAFASMDGPEGELVGKKPPAVPAPARPLPDYVGV
TH_0096|M.thermoresistible__bu LVQFGEIREDWYRLYRELMAPLEQPQGSLVGRPRPADPAPPAPLSTYVGT
MLBr_01782|M.leprae_Br4923 ARTYGHFGQ----------------SGGFIWADPEAELALVVLTDRDFGE
MAB_0330|M.abscessus_ATCC_1997 LAIYSPAEQT-----------------TVVALLNTDVAKQPAQPSTLFGT
MUL_1772|M.ulcerans_Agy99 PGAYGTWWQADPG--------ADLILLYLIQHCPDLSVNAAAAVAGNPGL
:. : .: *
Mb0931|M.bovis_AF2122/97 YANDYWGPATVTYHDGQLRLSLGPKN--------QTFDLTHWDGDTFTFT
Rv0907|M.tuberculosis_H37Rv YANDYWGPATVTYHDGQLRLSLGPKN--------QTFDLTHWDGDTFTFT
MMAR_4623|M.marinum_M YANDYWGPATVTERDGQLQLSMGPKN--------QTFDLTHWDGDTFTFA
MAV_1030|M.avium_104 YANDYWGPAVITEHDGALQLTMGPQH--------RTATLTHWDGDTFTFP
Mflv_1757|M.gilvum_PYR-GCK YGNDYWGPATVTERDGRLQLALGPR---------GVFELDAWDGNVFVFP
Mvan_4990|M.vanbaalenii_PYR-1 YRNDYWGPATVTERDGHLELALGPR---------GVFKLQPWDGNVFTFP
MSMEG_5637|M.smegmatis_MC2_155 YRNDYWGPATVTEQDGALQLALGPK---------FKARLTHWDGDVFTFR
TH_0096|M.thermoresistible__bu YHNDYWGPARVTERDGKLVLDMGPPDARPQPGAPDEFPLTHWDGNVFTFT
MLBr_01782|M.leprae_Br4923 WALQLWPAISDAVISEYAR-------------------------------
MAB_0330|M.abscessus_ATCC_1997 AITKVISPDHVFLLENAIPQPR----------------------------
MUL_1772|M.ulcerans_Agy99 AKLRTAQPRFVRRTYRALGL------------------------------
.
Mb0931|M.bovis_AF2122/97 LSTENALPGSISKATFAG---DTLNLEYYDADKLGTFTR
Rv0907|M.tuberculosis_H37Rv LSTENALPGSISKATFAG---DTLNLEYYDADKLGTFTR
MMAR_4623|M.marinum_M LSTENALPGSISKATFAG---DTLNLEYFDSNKLGTFTR
MAV_1030|M.avium_104 LTGENAPPGTVSTATFTGSPAARLNLEYYDTDQLGTFTR
Mflv_1757|M.gilvum_PYR-GCK VSSENAPPGTVSAATFDG---GALTLEYFDQEGNGVFVR
Mvan_4990|M.vanbaalenii_PYR-1 VSSENAPPGTVSAATFDA---GSLTLEYFDDEGKGVFTR
MSMEG_5637|M.smegmatis_MC2_155 FVSENAPPGTISKATFAG---DKLTLEYFDEDGTGTFTR
TH_0096|M.thermoresistible__bu LVTENAPPGTISKATFDG---DRLTLEYYDDVHDGVFVK
MLBr_01782|M.leprae_Br4923 ---------------------------------------
MAB_0330|M.abscessus_ATCC_1997 ---------------------------------------
MUL_1772|M.ulcerans_Agy99 ---------------------------------------