For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4110 (-)

annotation: aldehyde dehydrogenase
coordinates: 5065092 - 5067761
length: 889

MTTTPTESASPVEAPAIDNLRTAEIDAIVDTAAEAARAFRKLDQQQVDAIVEAMVRAGVRAAGELAGVAI
EETGFGVFEDKVVKNYVATEFLHDYLRGKKSVGVIDEDVEHNIVYVAEPIGVVLGITPVTNPTSTVLFKA
IVAAKTRNAILFRPSPYAVRCCEQSIEILRTAAEAAGMPPGALQVIPDAAHEVTHYLFKHPKVDFIWVTG
GPKIVALANSAGKPGLSVGPGNAPIYIHKTADLKGAVVDILISKTFDSSVICPAEQTCIIDDEIYDEMIA
EFERMGAQLLTADQAKAVAEFAFGCGDKVSLDAVGQKAPELAARAGFSVPPTVKVLLAQLPSDLGELAAH
PLVQEKLMPVLGVVRARSVQHGIDAAVLVTEHGGLGHTSAIYANDDDVIEAYGLAVRTGRILVNAPTAVG
ALGGVYNNLTPTFSLGCGTWGGSSTTENVNYRQLLNIKTVSRRRTPPQWFRVPSNTYFNEGALDNLRELD
CETVVVVTDALTEERGVVEALRGKLRAQHVQVFSEVTPEPDETTIRRGVALMQRVQPDLLIAIGGGSVLD
AGKAMRLFYEHPEKSLDALTMPFLDPRKRVADYPTDRHRIQLVAVPTTSGTGSEVSPAAVLTVGGKKETL
VDYSLVPDLAIVDPVLTSSMPQKLTADTGIDALTHALEAIVSIFASPYTDALCAQAVRLIFDALPRAYDD
PDDLSARTSMSNAATLAGLAFSNAFVGTNHALAHAVGAKFSVPHGRANGIFLPHVLRYNASLPTKFMPAP
GYSAYIAPDKYAQLGQLVFGGHLPDDSRQRLFAGVDDLLDRLDMPRSLREFGVDEQEFLAALPTLAMTAF
EDLSNRTNPRMPLVSEITDLLRLGYYGDTGVGEPALAPIKPGDVDGRSV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4110--100% (889)aldehyde dehydrogenase
M. marinum MMMAR_4246aldA_11e-1425.70% (323) NAD-dependent aldehyde dehydrogenase, AldA_1
M. marinum MMMAR_3556-5e-1324.26% (408) aldehyde dehydrogenase NAD dependent

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2451cproA5e-1231.58% (190) gamma-glutamyl phosphate reductase
M. gilvum PYR-GCKMflv_1242-2e-7137.76% (429) aldehyde dehydrogenase
M. tuberculosis H37RvRv2427cproA5e-1231.58% (190) gamma-glutamyl phosphate reductase
M. leprae Br4923MLBr_01458proA8e-1527.48% (302) gamma-glutamyl phosphate reductase
M. abscessus ATCC 19977MAB_3328-4e-1625.84% (298) gamma-aminobutyraldehyde dehydrogenase
M. avium 104MAV_1747proA8e-1527.15% (302) gamma-glutamyl phosphate reductase
M. smegmatis MC2 155MSMEG_0276-2e-7136.85% (445) aldehyde-alcohol dehydrogenase
M. thermoresistible (build 8)TH_3419-3e-1626.28% (449) PUTATIVE putative aldehyde dehydrogenase
M. ulcerans Agy99MUL_3976-0.099.21% (889) bifunctional acetaldehyde-CoA/alcohol dehydrogenase
M. vanbaalenii PYR-1Mvan_0443-0.085.11% (853) bifunctional acetaldehyde-CoA/alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4110|M.marinum_M               --------------------------MTTTPTESASPVEAPAIDNLRTAE
MUL_3976|M.ulcerans_Agy99           --------------------------MTTTPTESASPVEAPAIDNLRTAE
Mvan_0443|M.vanbaalenii_PYR-1       --------------------------MSTT--------------QMRRGE
Mflv_1242|M.gilvum_PYR-GCK          --------------------------------------------MIAVPH
MSMEG_0276|M.smegmatis_MC2_155      ----------------------------------MSEVIQDRRSAVDTAR
Mb2451c|M.bovis_AF2122/97           --------------------------------MTVP----APSQLDLRQE
Rv2427c|M.tuberculosis_H37Rv        --------------------------------MTVP----APSQLDLRQE
MAV_1747|M.avium_104                --------------------MGLQAPFRSGGGTSRPQGRAAPRAVDLRRE
MLBr_01458|M.leprae_Br4923          ----------------------------------------------MRQE
MAB_3328|M.abscessus_ATCC_1997      --------MSVPSSWINGR-PVATHGDTHRVINPATGEAVADLKLATTAD
TH_3419|M.thermoresistible__bu      VQRTLPDKLPAPRLVIGGGDVISTSGGVYEHHYAATGGVQAEVPLAGPAE
                                                                                      

MMAR_4110|M.marinum_M               IDAIVDTAAEAARAFRKLDQQQVDAIVEAMVRAGVRAAGELAGVAIEETG
MUL_3976|M.ulcerans_Agy99           IDAIVDTAAEAARAFRKLDQQQVDAIVEAMVRAGVRAAGELAGVAIEETG
Mvan_0443|M.vanbaalenii_PYR-1       IDAVVDKAAAAAAEFRKLDQAQVDAIVEAMVRAGIRAAAALAQVAIEETG
Mflv_1242|M.gilvum_PYR-GCK          AGQLLERAHFAASAYADYDQASVARIVDAVAEAGHRNAERFAAAAVAETQ
MSMEG_0276|M.smegmatis_MC2_155      AGHMLERARWAAAAYGEYDAATVEGIVAAVAEAAHAHAERFAADAVAETG
Mb2451c|M.bovis_AF2122/97           VHDAARRARVAARRLASLPTTVKDRALHAAADELLAHRDQILAANAEDLN
Rv2427c|M.tuberculosis_H37Rv        VHDAARRARVAARRLASLPTTVKDRALHAAADELLAHRDQILAANAEDLN
MAV_1747|M.avium_104                VHDAARRARVASRVLALLPTVAKDQALRSAADAIAGHAELILSANAEDLE
MLBr_01458|M.leprae_Br4923          VHDAARRARVAARALAVMPTVAKDHALRAAATAVTAHTEEILAANAEDLQ
MAB_3328|M.abscessus_ATCC_1997      VDAAVAAARAAGPAWASSTPVDRSSVLAKLAAVLSANADTLVADEVAQTG
TH_3419|M.thermoresistible__bu      VDAAVAAARAAFPAWRDLDLNRRRDILQELARRLVADGERLGAIATLEVG
                                           *  *               :   .         :      :  

MMAR_4110|M.marinum_M               FG-------VFEDKVVKNYVATEFLHDYLRGKKSVGVIDEDVEH------
MUL_3976|M.ulcerans_Agy99           FG-------VFEDKVVKNYVATEFLHDYLRGKKSVGVIDEDVEH------
Mvan_0443|M.vanbaalenii_PYR-1       FG-------VFEDKVVKNYVATEFLHDYLRDKKSVGVVEEDIEN------
Mflv_1242|M.gilvum_PYR-GCK          MG-------VVEHKVTKNRACSRGIVEFYRDQ-DYVTPRIDTAR------
MSMEG_0276|M.smegmatis_MC2_155      MG-------VVADKVRKNRACSRGIVEYYRGH-DYISPRVDPDR------
Mb2451c|M.bovis_AF2122/97           AAREADTPAAMLDRLSLNPQRVDGIAAGLRQVAGLRDPVGEVLRGYTLPN
Rv2427c|M.tuberculosis_H37Rv        AAREADTPAAMLDRLSLNPQRVDGIAAGLRQVAGLRDPVGEVLRGYTLPN
MAV_1747|M.avium_104                TARAAGTPSAMLDRLALDTKRVEGIAAGLRQVAGLPDPVGEVLRGYTLPN
MLBr_01458|M.leprae_Br4923          AARATDTLAATLDRLALDRQRIDQIAGGLRQVAALPDPIGEVLRGYTLPN
MAB_3328|M.abscessus_ATCC_1997      KP----VRLASEFDVPGSIDNVEFFAGAARHLEGKATAEYSADH------
TH_3419|M.thermoresistible__bu      TP----NLLASS-SSAMAADWFTYYAGWIGRSAGEVVPVPAGGA------
                                             .                                        

MMAR_4110|M.marinum_M               --NIVYVAEPIGVVLGITPVTNPTSTVLFKAIVAAKTRNAILFRPSPYAV
MUL_3976|M.ulcerans_Agy99           --NIVYVAEPIGVVLGITPVTNPTSTVLFKAIVAAKTRNAILFRPSPYAV
Mvan_0443|M.vanbaalenii_PYR-1       --NIVRVAEPIGVVLAITPVTNPTSTVLFKAIVAAKTRNAIVFRPSPYAV
Mflv_1242|M.gilvum_PYR-GCK          --KIVEIPRPAGVVLALTPTTNPVATVYFKVILALMTRNAVVVAPHPRAR
MSMEG_0276|M.smegmatis_MC2_155      --KIVELPRPAGVVLALTPTTNPVATVYFKTILALMTRNAVVVAPHPRAA
Mb2451c|M.bovis_AF2122/97           GLQLRQQRVPLGVVGMIYEGRPNVTVDAFG--LTLKSGNAALLRGSSSAA
Rv2427c|M.tuberculosis_H37Rv        GLQLRQQRVPLGVVGMIYEGRPNVTVDAFG--LTLKSGNAALLRGSSSAA
MAV_1747|M.avium_104                GLQLRQQRVPLGVVGMIYEGRPNVTVDAFG--LALKSGNAVLLRGSSSAT
MLBr_01458|M.leprae_Br4923          GLQLRQQRVPLGVVGMIYEGRPNITVDAFG--LAFKSGNAALLRGSSSAA
MAB_3328|M.abscessus_ATCC_1997      --TSSIRREAAGVVATITPWNYPLQMAVWKVLPALAAGCTVVIKPSELTP
TH_3419|M.thermoresistible__bu      --LDYVLDEPLGVIAAIIPWNGPLISIGMKVAPALAAGNCVVLKPPENAP
                                             . **:  :                :  :    :.     : 

MMAR_4110|M.marinum_M               RCCEQSIEILRTAAEAAGMPPGALQVIPDAAHEVTHYLFKHP-KVDFIWV
MUL_3976|M.ulcerans_Agy99           RCCEQSIEILRTAAEAAGMPPGALQVIPDAAHEVTHYLFKHP-KVDFIWV
Mvan_0443|M.vanbaalenii_PYR-1       RCCERSVEILREAAEAAGMPTGALQVIPDEAHEVTHYLFAHE-KIDFLWV
Mflv_1242|M.gilvum_PYR-GCK          QCSADAARVLAEAAEAAGAPDGIVQVIDEPSLPLVEALMSDE-RTDVIVA
MSMEG_0276|M.smegmatis_MC2_155      RCSAEAARVLAEAAVAAGAPDGVVQVIDEPSIPLVQALMADE-RTDVIVA
Mb2451c|M.bovis_AF2122/97           KSNEALVAVLRTALVGLELPADAVQLLSAADRATVTHLIQARGLVDVVIP
Rv2427c|M.tuberculosis_H37Rv        KSNEALVAVLRTALVGLELPADAVQLLSAADRATVTHLIQARGLVDVVIP
MAV_1747|M.avium_104                RSNQALVQVLRASLVSEDLPADAVQLLSADDRATVTHLIQARGLVDVVIP
MLBr_01458|M.leprae_Br4923          KSNQALVEVLHAALVSEDLPADAVQLLSAADRSTVTHLIQARGLVDVVIP
MAB_3328|M.abscessus_ATCC_1997      ----LTTLTLARLAAEAGLPEGVLNVVTGRGDDVGYALASHP-DVDLVTF
TH_3419|M.thermoresistible__bu      ----FSALRFAELAAEAGLPPGVLNVIPG-GAEAGSALCSHP-GVDKITF
                                             :         * . ::::          *       * :  

MMAR_4110|M.marinum_M               TGGP----KIVALAN-SAGKPGLSVGPGNAPIYIHKTADLKGAVVDILIS
MUL_3976|M.ulcerans_Agy99           TGGP----KIVALAN-SAGKPGLSVGPGNAPIYIHKTADLKGAVVDILIS
Mvan_0443|M.vanbaalenii_PYR-1       TGGP----KIVALAN-AAGKPGLCVGPGNAPIYIHKTADVRGAVVDILIS
Mflv_1242|M.gilvum_PYR-GCK          TGGT----GVVRAAY-SSGNPALGVGPGNVPVFVDATADIDAAARRIVDS
MSMEG_0276|M.smegmatis_MC2_155      TGGT----AVVRAAY-SSGNPALGVGPGNVPVLVDASADVAAAAQRIVDS
Mb2451c|M.bovis_AF2122/97           RGGA----GLIEAVVRDAQVPTIETGVGNCHVYVHQAADLDVAERILLNS
Rv2427c|M.tuberculosis_H37Rv        RGGA----GLIEAVVRDAQVPTIETGVGNCHVYVHQAADLDVAERILLNS
MAV_1747|M.avium_104                RGGA----NLINAVVRDAQVPTIETGVGNCHVYVHEGADLEVAERVLLNS
MLBr_01458|M.leprae_Br4923          RGGA----NLIDAVVRDAQVPIIETGVGNCHVYVHQAADLEVAERILLNS
MAB_3328|M.abscessus_ATCC_1997      TGSTAVGRKVMAAAAVHGHRTQLELG-GKAPFVVFDDADMDAAIAGAV-A
TH_3419|M.thermoresistible__bu      TGGGETARKVFAAAAQALTPVVLELG-GKSANIVFPDADLDAAATMAVSA
                                     *.      :.  .        :  * *:    :   **:  *    : :

MMAR_4110|M.marinum_M               KTFDS-SVICPAEQTCIIDDEIYDEMIAEFERMGAQLLTADQAKAVAEFA
MUL_3976|M.ulcerans_Agy99           KTFDS-SVICPAKQTCIIDDEIYDEMIAEFERMGAQLLTADQAKAVAEFA
Mvan_0443|M.vanbaalenii_PYR-1       KTFDS-SVICPAEQTCVIDDEIYDAMIAEFERMGARLLTEEETSAIARFA
Mflv_1242|M.gilvum_PYR-GCK          KAFDN-SVLCTNESVLIAEESIAAKLRTSLTRHGAHILDADAADRLREYM
MSMEG_0276|M.smegmatis_MC2_155      KAFDN-SVLCTNESVLIAEDAVADKLRAALTRAGAHILDEDGARRLRAYM
Mb2451c|M.bovis_AF2122/97           KTRR--PSVCNAAETLLVDAAIAETALPRLLAA-----------------
Rv2427c|M.tuberculosis_H37Rv        KTRR--PSVCNAAETLLVDAAIAETALPRLLAA-----------------
MAV_1747|M.avium_104                KTRR--PSVCNAAETLLVDAAIAEEALPRLVTA-----------------
MLBr_01458|M.leprae_Br4923          KTRR--PSVCNAAETLLIDAAIADHTMPRLVAA-----------------
MAB_3328|M.abscessus_ATCC_1997      GAIINSGQDCTAATRALVARDLYDDFVAGVGEVMSKVVVGDPLDPDTDIG
TH_3419|M.thermoresistible__bu      GLMMLSGQGCILPTRLLVHDDVYDEMVTRVVAGADALTVGDPWQPTTMMG
                                             *      :    :     . .                    

MMAR_4110|M.marinum_M               FGCGDKVSLDAVGQKAPELAARAGFSVPPTVKVL---LAQLPSDLGELAA
MUL_3976|M.ulcerans_Agy99           FGCGDKVSLDAVGQKAPELAARAGFSVPPTVKVP---LAQLPSDLDELAA
Mvan_0443|M.vanbaalenii_PYR-1       FGCGDKIALEALGQKAPELAARAGFSVPPTVKVL---LAALPADLEELAA
Mflv_1242|M.gilvum_PYR-GCK          FPDG-ALNTEVVGRDAAWIAERIGLRVTPKTRVL---IAPFT---DVIGE
MSMEG_0276|M.smegmatis_MC2_155      FADG-HLNTDVVGRDAAWIAGQAGLRVTPKTRVL---IAPFD---HVIAE
Mb2451c|M.bovis_AF2122/97           -------------LQHAGVTVH----LDPDE-------------------
Rv2427c|M.tuberculosis_H37Rv        -------------LQHAGVTVH----LDPDE-------------------
MAV_1747|M.avium_104                -------------LQDAGVTVHGGFARDATE-------------------
MLBr_01458|M.leprae_Br4923          -------------LQGAGVTVHGGLSGDPDK-------------------
MAB_3328|M.abscessus_ATCC_1997      PLISAAHRAKVSSIVDRAP-AQGGRIVTGATAPD--LPGSFYRPTLIADV
TH_3419|M.thermoresistible__bu      PLATAAQLERVTRAVDSALSDKAGKLLAGGRRPDGLDAGYFYRPTVFGDV
                                                         :                            

MMAR_4110|M.marinum_M               HPLVQEKLMPVLGVVRARSVQHGIDAAVLVTEHGGLGHTSAIYANDDDVI
MUL_3976|M.ulcerans_Agy99           HPLVQEKLMPVLGVVRARSVQHGIDAAVLVTEHGGLGHTSAIYANDDDVI
Mvan_0443|M.vanbaalenii_PYR-1       HPLVQEKLMPVLGVVRARSVDHAIDVAVLVTEHGGLGHTSAVYANDQAVV
Mflv_1242|M.gilvum_PYR-GCK          EVLTHEKLCPVLGMTTVADAPRGIRAARAVVRIAGAGHSAAIHSEDASVI
MSMEG_0276|M.smegmatis_MC2_155      EMLAHEKLSPVLGMTTVADAARGIRAARAVVRIGGAGHSAAIHSENPAVI
Mb2451c|M.bovis_AF2122/97           ----ADLRREYLSLDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNLDAA
Rv2427c|M.tuberculosis_H37Rv        ----ADLRREYLSLDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNLDAA
MAV_1747|M.avium_104                ----DDLRREYLSMDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNMAAA
MLBr_01458|M.leprae_Br4923          ----ADLCREYLSMDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNMAAA
MAB_3328|M.abscessus_ATCC_1997      AETSEVYRDEIFGPVLTVRPFTDDDDALRQANDTAYGLAASAWTRDVYRA
TH_3419|M.thermoresistible__bu      DPASDLAQTEIFGPVLAILRFRSEEEAVELANNTQYGLAAYIHTRDLRRA
                                               :.   .         *    .    * :    : :    

MMAR_4110|M.marinum_M               EAYGLAVRTGRILVNAPTAVGALGGVYNNLTPTFSLGCGTWGGSSTTENV
MUL_3976|M.ulcerans_Agy99           EAYGLAVRTGRILVNAPTAVGALGGVYNNLTPTFSLGCGTWGGSSTTENV
Mvan_0443|M.vanbaalenii_PYR-1       DAYSAAVRTGRILVNAPTAVGALGGVYNNLTPTFSLGCGTWGGSRTTENV
Mflv_1242|M.gilvum_PYR-GCK          TEFAAKVPVLRVSVNVGNSTGSSG-LDTNLAPSMTIGTGFVGRSSIGENL
MSMEG_0276|M.smegmatis_MC2_155      TDFAAQVPVLRVSVNVGNSTGSAG-LDTNLAPSMTIGTGFVGRSSIGENL
Mb2451c|M.bovis_AF2122/97           QRFTEQIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPEL
Rv2427c|M.tuberculosis_H37Rv        QRFTEQIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPEL
MAV_1747|M.avium_104                QRFTDGVDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPEL
MLBr_01458|M.leprae_Br4923          QRFADGVDSATVMVNASTAFTDGGQFGFGAEIGISTQKLHARGPMGLSEM
MAB_3328|M.abscessus_ATCC_1997      QRASREIRAGCVWINDHIPIISEMPHGGFGASGFGKDMSDYSLEEYLTVK
TH_3419|M.thermoresistible__bu      HVMAAALDAGGVAVNGFPIVPSAAPFGGVKQSGFGREGGIWGLREFQRTK
                                          :    : :*                  :                

MMAR_4110|M.marinum_M               NYRQLLNIKTVSRRRTPPQWFRVPSNTYFNEGALDNLRELDCETVVVVTD
MUL_3976|M.ulcerans_Agy99           NYRQLLNIKTVSRRRTPPQWFRVPSNTYFNEGALDNLRELDCETVVVVTD
Mvan_0443|M.vanbaalenii_PYR-1       NYRQLLNIKTVAQRRTPPQWFRVPSNTYFNAGALENLRDLDCETVVIVTD
Mflv_1242|M.gilvum_PYR-GCK          QPENLLNWARIAYNADTAVTMPNFAG------------------------
MSMEG_0276|M.smegmatis_MC2_155      QPHNLVNWTRIAYNSDPGVVMGNFTG------------------------
Mb2451c|M.bovis_AF2122/97           TSTKWIAWGAGHTRPA----------------------------------
Rv2427c|M.tuberculosis_H37Rv        TSTKWIAWGAGHTRPA----------------------------------
MAV_1747|M.avium_104                TSTKWIAWGDGQTRPA----------------------------------
MLBr_01458|M.leprae_Br4923          TSTKWIVWGDGQIRPA----------------------------------
MAB_3328|M.abscessus_ATCC_1997      HVMSDITGTADKDWHRTIFAKR----------------------------
TH_3419|M.thermoresistible__bu      NVYIGLQ-------------------------------------------
                                         :                                            

MMAR_4110|M.marinum_M               ALTEERGVVEALRGKLRAQHVQVFSEVTPEPDETTIRRGVALMQRVQPDL
MUL_3976|M.ulcerans_Agy99           ALTEERGVVEALRGKLRAQHVQVFSEVTPEPDETTIRRGVALMQRVQPDL
Mvan_0443|M.vanbaalenii_PYR-1       AASDERGVVDLLRGKLRTRHVQVFSEVPPEPDESMIRRGVQLLERVQPEV
Mflv_1242|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0276|M.smegmatis_MC2_155      --------------------------------------------------
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               LIAIGGGSVLDAGKAMRLFYEHPEKSLDALTMPFLDPRKRVADYPTDRHR
MUL_3976|M.ulcerans_Agy99           LIAIGGGSVLDAGKAMRLFYEHPEKSLDALTMPFLDPRKRVADYPTDRHR
Mvan_0443|M.vanbaalenii_PYR-1       LIAVGGGSVLDAGKAMRLFFEHPEKTLDELTMPFLDPRKRVADYPTDRHR
Mflv_1242|M.gilvum_PYR-GCK          ------------------------------LSPWHAPTGPVPAYPRASND
MSMEG_0276|M.smegmatis_MC2_155      ------------------------------IDPWRAPAGPVPAYPRASND
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               IQLVAVPTTSGTGSEVSPAAVLTVGGKKETLVDYSLVPDLAIVDPVLTSS
MUL_3976|M.ulcerans_Agy99           IQLVAVPTTSGTGSEVSPAAVLTVGGKKETLVDYSLVPDLAIVDPVLTSS
Mvan_0443|M.vanbaalenii_PYR-1       LQLVAVPTTSGTGSEVSPAAVLTVRGRKQTLVDYSLVPDLAIVDPVLTSS
Mflv_1242|M.gilvum_PYR-GCK          QS-ATPAPAPAAS----------------------------------VSR
MSMEG_0276|M.smegmatis_MC2_155      RDGAVIQAAPQRS----------------------------------YQS
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               MPQKLTADTGIDALTHALEAIVSIFASPYTDALCAQAVRLIFDALPRAYD
MUL_3976|M.ulcerans_Agy99           MPQKLTADIGIDALTHALEAIVSIFASPYTDALCAQAVRLIFDALPRAYD
Mvan_0443|M.vanbaalenii_PYR-1       MPPVLTADTGIDALTHALEAVVSIFASPYTDALCAQAARLIFDALPRAYR
Mflv_1242|M.gilvum_PYR-GCK          PTAPRSADPGIEALRAELRALVAEELAQLIKR------------------
MSMEG_0276|M.smegmatis_MC2_155      P--SRTTDVNLDALRAELRALVVEELAQLIKR------------------
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               DPDDLSARTSMSNAATLAGLAFSNAFVGTNHALAHAVGAKFSVPHGRANG
MUL_3976|M.ulcerans_Agy99           DPDDLSARTSMSNAATLAGLAFSNAFVGTNHTLAHAVGAKFSVPHGRANG
Mvan_0443|M.vanbaalenii_PYR-1       DPEDLAARTDMSNAATLAGLAFSNAFVGTNHALAHAVGAKFGIAHGRANA
Mflv_1242|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0276|M.smegmatis_MC2_155      --------------------------------------------------
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               IFLPHVLRYNASLPTKFMPAPGYSAYIAPDKYAQLGQLVFGGHLPDDSRQ
MUL_3976|M.ulcerans_Agy99           IFLPHVLRYNASLPTKFMPAPGYSAYIAPDKYAQLGQLVFGGHLPDDSRQ
Mvan_0443|M.vanbaalenii_PYR-1       IFLPHVLRYNASLPSKFMPAPGYSAYIAPDKYAQIGQLIFGGHEPEDSRG
Mflv_1242|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0276|M.smegmatis_MC2_155      --------------------------------------------------
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               RLFAGVDDLLDRLDMPRSLREFGVDEQEFLAALPTLAMTAFEDLSNRTNP
MUL_3976|M.ulcerans_Agy99           RLFAGVDDLLDRLDMPRSLREFGVDEQGFLVALPTLAMTAFEDLSNRTNP
Mvan_0443|M.vanbaalenii_PYR-1       RLFLGVQDLLEQLDMPGSLKAIGVSEDAFTAALPELAMTAFEDLSNRTNP
Mflv_1242|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0276|M.smegmatis_MC2_155      --------------------------------------------------
Mb2451c|M.bovis_AF2122/97           --------------------------------------------------
Rv2427c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1747|M.avium_104                --------------------------------------------------
MLBr_01458|M.leprae_Br4923          --------------------------------------------------
MAB_3328|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3419|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_4110|M.marinum_M               RMPLVSEITDLLRLGYYGDTGVGEPALAPIKPGDVDGRSV
MUL_3976|M.ulcerans_Agy99           RMPLVSEITDLLRLGYYGDTGVGEPALAPIKPGDVDGRSV
Mvan_0443|M.vanbaalenii_PYR-1       RMPLVSEISDLLRLGYYGSEAPG-----------------
Mflv_1242|M.gilvum_PYR-GCK          ----------------------------------------
MSMEG_0276|M.smegmatis_MC2_155      ----------------------------------------
Mb2451c|M.bovis_AF2122/97           ----------------------------------------
Rv2427c|M.tuberculosis_H37Rv        ----------------------------------------
MAV_1747|M.avium_104                ----------------------------------------
MLBr_01458|M.leprae_Br4923          ----------------------------------------
MAB_3328|M.abscessus_ATCC_1997      ----------------------------------------
TH_3419|M.thermoresistible__bu      ----------------------------------------