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MPATLSQIEAWSTEHLIDAAAYWTQTADRWEDAFLTMRNQAQSITWHGAGGDALRQRTGADLSVVSGKAD LLRQAAGIARNGASDISAAQRRVLYGVEDALNAGFTVGEDLSVTDTRSTSPAERAARQAQAEAFAADIRL RAEQLDGADTKVSGQLTAATAGLSGGGFAQNSTSNRGGRAQNSSGNGGQPQPGHNAGQPQPATTNHNGVR LVDFTQDNASGPNPPPFAPWDNPDGAPPAPAPVQPGVIPQLEQSMTAPPAPKPGPPASPLPSPSVTPLPN PAAVGPAAAAPAKPPCSPYDATKAILEPPIGMVGILTAVPESLTIAGIPAALTQIGVGTVAVADGLDAAD KCLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2254 | - | - | 100% (354) | hypothetical protein MAV_2254 |
| M. avium 104 | MAV_1479 | - | 1e-98 | 56.27% (375) | hypothetical protein MAV_1479 |
| M. avium 104 | MAV_1450 | - | 4e-94 | 66.20% (287) | hypothetical protein MAV_1450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 2e-63 | 45.13% (359) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 3e-24 | 37.00% (200) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 2e-63 | 45.13% (359) | transmembrane protein |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 2e-05 | 31.25% (96) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_0016 | - | 7e-13 | 27.95% (161) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0116 | - | 4e-85 | 65.75% (254) | hypothetical protein MMAR_0116 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 4e-24 | 39.16% (166) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 5e-20 | 37.21% (172) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 1e-51 | 46.84% (269) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 1e-18 | 37.04% (162) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2254|M.avium_104 -----------MPATLSQIEAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MMAR_0116|M.marinum_M -----------MPATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQMRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
MLBr_02395|M.leprae_Br4923 ------------MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAY
. . ..
MAV_2254|M.avium_104 ---QAQSITWHGAGGDALRQRTGADLSVVSGKADLLRQAAGIARNGASDI
MMAR_0116|M.marinum_M ---QSYALGWSGAGGDALRERTSADLPIVGAKADMLRQAAGIAGNGASDI
MUL_1136|M.ulcerans_Agy99 ---QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAGTI
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
MLBr_02395|M.leprae_Br4923 PPPTAPPVGGSYPPPPPPGGSYPPPPPPGGSYPPPPPSTGAYAPPPPGPA
*
MAV_2254|M.avium_104 SAAQRRVLYGVEDALNAGFTVGEDLSVTDT-RSTSPAERAARQAQAEAFA
MMAR_0116|M.marinum_M SAAQRRVLYAVEDAHNAGFTVGEDLSVTDTHRSGTPAEQAARQAQAQAFA
MUL_1136|M.ulcerans_Agy99 GIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRRSAEQAARQAQAQAQA
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYDLET-AAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVST-MAARYTAAREHA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTER-RSHSGLDRLKRAIRRRWLQ
MLBr_02395|M.leprae_Br4923 IRSLPKEAYTFWVTRVLAYVIDN---IPATVLLGIGMLIQTLTKQEACVT
: . . : : : :
MAV_2254|M.avium_104 ADIRLRAEQLDGADTKVSGQLTAATAGLSGGGFAQNSTSN----------
MMAR_0116|M.marinum_M GDIRLHARQLDGADAKVAGQLTAATADLSSVGFAQN--------------
MUL_1136|M.ulcerans_Agy99 QATDIRQRAVEPVPPPAPGRLPPLTPGEMATP------------------
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATTGDVGNVR------------------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATTGDVGNVR------------------
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFAR---------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGE---------------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGN-----------
MLBr_02395|M.leprae_Br4923 DITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWN-------------
. *
MAV_2254|M.avium_104 -------------------------RGGRAQNSSGNGGQPQPGHNAGQPQ
MMAR_0116|M.marinum_M ---------------------------------------PIP-----ATQ
MUL_1136|M.ulcerans_Agy99 ---------------------------------------RLP-----APP
Mb2102c|M.bovis_AF2122/97 -----------------------------------------------FAG
Rv2077c|M.tuberculosis_H37Rv -----------------------------------------------FAG
TH_3926|M.thermoresistible__bu -------------------------------------------------N
Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------------------G
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
MAB_0016|M.abscessus_ATCC_1997 ------------------------------------TDFSGDPNHPKIMG
MLBr_02395|M.leprae_Br4923 -----------------------------------------------YGY
MAV_2254|M.avium_104 PATTNHNGVRLVDFTQDNASGPNPPPFAPWDNPDGAPPAP----------
MMAR_0116|M.marinum_M APTTHRNGVQLVDFKQN---GGEPPPFAPWDTPDGTPP------------
MUL_1136|M.ulcerans_Agy99 PQPPIRGGADLAP--------AEPPPVVRTPMEP----------------
Mb2102c|M.bovis_AF2122/97 APVVAHSAVQLVDFFKQD--GPTPPPPGAPHPSGGADG------------
Rv2077c|M.tuberculosis_H37Rv APVVAHSAVQLVDFFKQD--GPTPPPPGAPHPSGGADG------------
TH_3926|M.thermoresistible__bu PIIQPLSTDSDEHHFGTCFAESFKEDVG----------------------
Mvan_5711|M.vanbaalenii_PYR-1 PVIAPIAAGDDGQSFGQCFADRFKDDIG----------------------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----------
MAB_0016|M.abscessus_ATCC_1997 PAKPLGPIEQEDYDLGYTFLDENGNPLPMLDENGNVVIDPKTG-------
MLBr_02395|M.leprae_Br4923 RQGATGSSIGKTVMKFKVISEATGQPIG----------------------
MAV_2254|M.avium_104 --------------------------------------APVQPGVIPQLE
MMAR_0116|M.marinum_M ---------------------------------------PGAPGLSPELQ
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 ---------------------------------------PYSDPITSMML
Rv2077c|M.tuberculosis_H37Rv ---------------------------------------PYSDPITSMML
TH_3926|M.thermoresistible__bu ----------------------------------------------KNMV
Mvan_5711|M.vanbaalenii_PYR-1 ----------------------------------------------ENMV
Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA
MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------RPVPDSVWGDPA
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_2254|M.avium_104 QSMTAP-PAPKPG--------------------PPASPLPSPSVTPLP--
MMAR_0116|M.marinum_M QMILGGDPANLTG--------------------QGLLDNLQQLVQSLPEN
MUL_1136|M.ulcerans_Agy99 -------PARLGG--------------------PIAGGPVPPGSIPHP--
Mb2102c|M.bovis_AF2122/97 PPAGTEAPVSDAT--------------------KRWVDNMVNELAARPPD
Rv2077c|M.tuberculosis_H37Rv PPAGTEAPVSDAT--------------------KRWVDNMVNELAARPPD
TH_3926|M.thermoresistible__bu QGVFVGGAIGAAR--------------------GALMGILGGPIGVFG--
Mvan_5711|M.vanbaalenii_PYR-1 QGVFVGGALGALR--------------------GAVLGVLGGPLGMLG--
Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG
MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG--
MAB_0016|M.abscessus_ATCC_1997 DNNADGSPRVPHP----------------PRDHHFADMDANDPYRTLPTG
MLBr_02395|M.leprae_Br4923 ------FGMSVVR---------------------QLAHFVDAVICCIG--
MAV_2254|M.avium_104 NP-AAVGPAAAAPAKPPCSPYDATKAILEPPIGMVGILTAVPESLTIAGI
MMAR_0116|M.marinum_M DPRTAWLRGQVADLQAHMSDIDYARTHCTT-SDWFDRTTLFASGLVSTGI
MUL_1136|M.ulcerans_Agy99 -------------VQPPHSHHGPP--------------------VLGKDE
Mb2102c|M.bovis_AF2122/97 DP--IAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAG
Rv2077c|M.tuberculosis_H37Rv DP--IAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAG
TH_3926|M.thermoresistible__bu ----------GGVLGFVGGAAGGALIS-------------GPARTAVTSA
Mvan_5711|M.vanbaalenii_PYR-1 ----------GSVAGFVGGAAGGAMIS-------------GPARTAVTSA
Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN
MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI
MAB_0016|M.abscessus_ATCC_1997 TTVGPNGERIALVSRPPDDPAWAENQTKNGKSVYVTQTEAYDVTRQPPQS
MLBr_02395|M.leprae_Br4923 ---------------FLFPLWDSKRQT-------------LADKIMTTVC
MAV_2254|M.avium_104 PAALTQIGVG-TVAVADGLD--AADK----CLP-----------------
MMAR_0116|M.marinum_M LTLTAETGVGGVAAVASGFGTLVAGKNLLGCLVGSK--------------
MUL_1136|M.ulcerans_Agy99 LPDLGEFNPG----------------------------------------
Mb2102c|M.bovis_AF2122/97 PADWALLGAALLGVGGSGAAVVNCATK-----------------------
Rv2077c|M.tuberculosis_H37Rv PADWALLGAALLGVGGSGAAVVNCATK-----------------------
TH_3926|M.thermoresistible__bu WDCL----------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 WDCL----------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDAL
MSMEG_5600|M.smegmatis_MC2_155 WGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVTV
MAB_0016|M.abscessus_ATCC_1997 LGKLQGVDGSKVYQGSIVYDKASGRMYVVGNHGDGSGDTARGMWRSDPVD
MLBr_02395|M.leprae_Br4923 LPI-----------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANAL
MSMEG_5600|M.smegmatis_MC2_155 LRGVDVTQYLPR--------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PNHPNDWVKTLRYQGDVPSLPGSRESSLVALPHGGVALFGADDYAPAEGR
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVST
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 NMAVGAISAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPA
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVL
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 LRADVVDTRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS-----------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_2254|M.avium_104 -----------------
MMAR_0116|M.marinum_M -----------------
MUL_1136|M.ulcerans_Agy99 -----------------
Mb2102c|M.bovis_AF2122/97 -----------------
Rv2077c|M.tuberculosis_H37Rv -----------------
TH_3926|M.thermoresistible__bu -----------------
Mvan_5711|M.vanbaalenii_PYR-1 -----------------
Mflv_1972|M.gilvum_PYR-GCK KGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 -----------------
MAB_0016|M.abscessus_ATCC_1997 -----------------
MLBr_02395|M.leprae_Br4923 -----------------