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M. marinum M MMAR_4735 (-)

annotation: PE-PGRS family protein
coordinates: 5785047 - 5786729
length: 560

MSFVAVAPDLLATATMDLDRIGNAINAGSTAAAASTTEVAAAAADEISTAVAELFGAYARGYQIIGAQAA
MFHAEFVRALDIGAGAYWATEVANASPLQSLEQQLLAAINAPTQTLLGRPLIGNGADGAAGTGADGGAGG
LLYGNGGAGGSGGTAHPTGGRGGNAGLFGSGGIGGSGAAGAAGGTGGNGGLLYGAGGNGGAGGNAVIPGG
DGGMGGAGGAAGLIGQGGNGGVGGLGATGAAGVNPSPLPAGTPAAAGTPGGSDLGQPGAPGGPGDYGVST
ATVGQPGGEGGAGGDGNYVGGVGGTGGAGGVGAVGGDGGRGGDSTTGTVAKLGVGGTGGTGGAGGAGAAG
GNGGDGGSAIADSNEGGTGGTGGTGGTGGTGAVGGNGGTGGNGFVGGAGGSGGSGGVGAAGDGGGAGGVG
GAGGHGGLLFGDGGAGGSGGGGAMGGAGAAGGQGGTGGTGGDSSAIDDRLAGNGGNGGTGGDGGAGGDGG
NGGNGGAGGAGGLFGHTGASGAGGSAGTGGAGGNPGAGGDGGSAVIMPGISGADGRLGDAGADGVAGLSG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4735--100% (560)PE-PGRS family protein
M. marinum MMMAR_1161-e-16955.98% (602) PE-PGRS family protein
M. marinum MMMAR_3816-e-16154.66% (580) PE-PGRS family protein, PE_PGRS59

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3621cPE_PGRS581e-16554.41% (601) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-11046.63% (549) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3590cPE_PGRS581e-16554.41% (601) PE-PGRS family protein
M. leprae Br4923MLBr_01183-7e-1135.42% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-4734.40% (468) hypothetical protein MAB_4284c
M. avium 104MAV_4827-7e-2739.90% (208) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-8339.18% (559) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-6e-4339.87% (306) PUTATIVE -
M. ulcerans Agy99MUL_4367-1e-14247.83% (644) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-10846.19% (565) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3621c|M.bovis_AF2122/97           --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4735|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4735|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           ------------------------------------MSFVIVAPEALMSV
Rv3590c|M.tuberculosis_H37Rv        ------------------------------------MSFVIVAPEALMSV
MMAR_4735|M.marinum_M               ------------------------------------MSFVAVAPDLLATA
MUL_4367|M.ulcerans_Agy99           ------------------------------------MSFVSVGPGLLEAA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------MNIVLGVSMAPSSIQMV
                                                                                      

Mb3621c|M.bovis_AF2122/97           AS------------------------------------EVAGIGSALNAA
Rv3590c|M.tuberculosis_H37Rv        AS------------------------------------EVAGIGSALNAA
MMAR_4735|M.marinum_M               TM------------------------------------DLDRIGNAINAG
MUL_4367|M.ulcerans_Agy99           AR------------------------------------DLAGLGAGLREA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VEAAS---------------------------------YVADPEAALANA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VLEG-------------------------------EYADGATVEEDAIDV
                                                                                      

Mb3621c|M.bovis_AF2122/97           N--------------------AAAAAPTTG----------VLAAAADEVS
Rv3590c|M.tuberculosis_H37Rv        N--------------------AAAAAPTTG----------VLAAAADEVS
MMAR_4735|M.marinum_M               S--------------------TAAAASTTE----------VAAAAADEIS
MUL_4367|M.ulcerans_Agy99           N--------------------LAAAGATVG----------VLPAAGDEVS
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      G-------------------LSAVSAAQVG-----AVMPVVAESVASNYG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TG--------------------ADDAATAS---------APDRVISAILG
                                                                                      

Mb3621c|M.bovis_AF2122/97           AA-----MAALFGAHAQEYQRLSAQAAGFHAQFVQALN----AGVNSYAS
Rv3590c|M.tuberculosis_H37Rv        AA-----MAALFGAHAQEYQRLSAQAAGFHAQFVQALN----AGVNSYAS
MMAR_4735|M.marinum_M               TA-----VAELFGAYARGYQIIGAQAAMFHAEFVRALD----IGAGAYWA
MUL_4367|M.ulcerans_Agy99           AA-----IAELFGGFGREYQAMGARVALLHDDFVRALT----AGGSAYGQ
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      YQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHND
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAA
                                                                                      

Mb3621c|M.bovis_AF2122/97           AEAANASPLQAVEQQVLGLIN--GPAQTLLG--RPLIGNGADGAPGT-GQ
Rv3590c|M.tuberculosis_H37Rv        AEAANASPLQAVEQQVLGLIN--GPAQTLLG--RPLIGNGADGAPGT-GQ
MMAR_4735|M.marinum_M               TEVANASPLQSLEQQLLAAIN--APTQTLLG--RPLIGNGADGAAGT-GA
MUL_4367|M.ulcerans_Agy99           AEALNMWPLQELEQQALGVVN--APSMALFG--RPSIGNGVDGVAGT-GQ
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNG--GNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNG--GNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAG--GAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu      ----------------------------------------VDGDGGSGGR
MAB_4284c|M.abscessus_ATCC_199      TDFASHNPIASGNQVMSPSGN--VDSFNRGPLLDLSFGDLQFGNRDTTAI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESY
                                                                                      

Mb3621c|M.bovis_AF2122/97           PGGPGGLLWGNGG-------NGGSGVAGVGGPGGSGG-------------
Rv3590c|M.tuberculosis_H37Rv        PGGPGGLLWGNGG-------NGGSGVAGVGGPGGSGG-------------
MMAR_4735|M.marinum_M               DGGAGGLLYGNGG-------AGGSGGT-AHPTGGRGG-------------
MUL_4367|M.ulcerans_Agy99           AGGAGGILWGNGG-------NGGLGAA--GANGGAGG-------------
Mflv_5091|M.gilvum_PYR-GCK          TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155      TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu      TGLFSKLSRGGDG-----------------GDGGLGG-------------
MAB_4284c|M.abscessus_ATCC_199      GDGAVAVGGSNSGP-----IASGQGSTAVNGDVRDSN-------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSV
                                                                                      

Mb3621c|M.bovis_AF2122/97           ----AAGLFGHGGNGGAGGS-NAAGAGGVGGAGGA---------------
Rv3590c|M.tuberculosis_H37Rv        ----AAGLFGHGGNGGAGGS-NAAGAGGVGGAGGA---------------
MMAR_4735|M.marinum_M               ----NAGLFGSGGIGGSG---AAGAAGGTGGNG-----------------
MUL_4367|M.ulcerans_Agy99           ----SAGLIGTGGVGGAGGVGAAGMTGGSGGAGGGG--------------
Mflv_5091|M.gilvum_PYR-GCK          -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1       -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155      VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu      -------NGGHGGGTGIISLLSLAGNGGNGGNGYR---------------
MAB_4284c|M.abscessus_ATCC_199      --IINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AEEPETALARGAALAAANAPLFASSTAALAYAQDPG--------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           GWLVGNGGAGGFG-------------------------------------
Rv3590c|M.tuberculosis_H37Rv        GWLVGNGGAGGFG-------------------------------------
MMAR_4735|M.marinum_M               GLLYGAG-------------------------------------------
MUL_4367|M.ulcerans_Agy99           GWLWGAGGSGGAAGAGGSGGSGGWLWGNAGQTAGAGVGGAGGAGGAGDAG
Mflv_5091|M.gilvum_PYR-GCK          --AVGAAGAAG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --AIGTAGVAG---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GHAIGGNGGNGGN-------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VTVVDDHSQRNTTNIN----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---TGAVDQYSLP-------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           ------------------------------GVGTTVSGNGGAGGAAGAFG
Rv3590c|M.tuberculosis_H37Rv        ------------------------------GVGTTVSGNGGAGGAAGAFG
MMAR_4735|M.marinum_M               -------------------------------------GNGGAG-------
MUL_4367|M.ulcerans_Agy99           DQGVSGVAPGEAGAVGFAGGAGGAGGAGGNGVGGGVNGAGGAGGAGGVGG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------TVGTAGATGGTG----
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------AAGTAGATGGTG----
MSMEG_0868|M.smegmatis_MC2_155      ------------------------------GSTTAAGGNGGTGGTGRVIA
TH_3810|M.thermoresistible__bu      ----------------------------------TTDNNALDGGHG----
MAB_4284c|M.abscessus_ATCC_199      -----------------------------DSFNTDRSTNIGSGNTTNTEI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------DYLYVPVDPEPGDDELAYSAV
                                                                                      

Mb3621c|M.bovis_AF2122/97           NGGV----------------GGAGGAAVIGGLPGNGGAG-----------
Rv3590c|M.tuberculosis_H37Rv        NGGV----------------GGAGGAAVIGGLPGNGGAG-----------
MMAR_4735|M.marinum_M               -----------------------GNAVIPGGDGGMGGAG-----------
MUL_4367|M.ulcerans_Agy99           GGGAGASGVGAGVAGGDGGTGGAGGAAGVGGAAGTGGTG-----------
Mflv_5091|M.gilvum_PYR-GCK          -------------------TGANGGAGGVGGVGGTGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------VGGNGGAGQAGGIGGTGAAG-----------
MSMEG_0868|M.smegmatis_MC2_155      EGTGSTAEGTA--------TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAV
TH_3810|M.thermoresistible__bu      ---------------------GNGGNVGFFSLFNLGGAG-----------
MAB_4284c|M.abscessus_ATCC_199      G------------------SHNQANIGTSTSAGGSAAVG-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVG-----------
                                                                                      

Mb3621c|M.bovis_AF2122/97           -----GNAGLIGA-GGDGGVGGVG--------------------------
Rv3590c|M.tuberculosis_H37Rv        -----GNAGLIGA-GGDGGVGGVG--------------------------
MMAR_4735|M.marinum_M               -----GAAGLIGQ-GGNGGVGGLG--------------------------
MUL_4367|M.ulcerans_Agy99           -----GAAGVAGT-GGDGGDGGAGGAGSDASLAGQAGFAGGSGGAGGVGG
Mflv_5091|M.gilvum_PYR-GCK          ---AAGGAGGLGETGTTGGAGGVGGQ----------------------GT
Mvan_1264|M.vanbaalenii_PYR-1       ---AAGQAGTAGETGVTGGVGGIGGQ----------------------GT
MSMEG_0868|M.smegmatis_MC2_155      SGTATGGRGGDGIDGGTGGAGGMGEIYS--------------------GA
TH_3810|M.thermoresistible__bu      ---------------GWGGSGVDG--------------------------
MAB_4284c|M.abscessus_ATCC_199      -----GNAGLAGNAGLAGNAGLAG--------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----ISAVLALEIALAIGIRTTGTVALQP-----------------TPN
                                                                                      

Mb3621c|M.bovis_AF2122/97           APGTNGMNPPPNQT-SQAANGSPGANN----GAGSG--------------
Rv3590c|M.tuberculosis_H37Rv        APGTNGMNPPPNQT-SQAANGSPGANN----GAGSG--------------
MMAR_4735|M.marinum_M               ATGAAGVNPSPLPAGTPAAAGTPGGSD----LGQPG--------------
MUL_4367|M.ulcerans_Agy99           SAGAGGVNGSGGDGGAGAAGGAGGASAT---VAGSG--------------
Mflv_5091|M.gilvum_PYR-GCK          AGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-------------L
Mvan_1264|M.vanbaalenii_PYR-1       EGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-------------L
MSMEG_0868|M.smegmatis_MC2_155      DGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTAKAG
TH_3810|M.thermoresistible__bu      -VDVVGGNPDGGTPGAHGESHTPGVYTD----------------------
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG--------------
MLBr_01183|M.leprae_Br4923          MPLFLNAEPQALTAAANTLEGLSAAT------------------------
MAV_4827|M.avium_104                QHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKP-------------L
                                                                                      

Mb3621c|M.bovis_AF2122/97           --GAGLPGNPGAVPG-----------------------------RAGGAG
Rv3590c|M.tuberculosis_H37Rv        --GAGLPGNPGAVPG-----------------------------RAGGAG
MMAR_4735|M.marinum_M               --APGGPGDYGVSTA-----------------------------TVGQPG
MUL_4367|M.ulcerans_Agy99           --GVGGDGGAGGAAGGGVGAASLGGDGGHAGAGGAGGEGLSGGFNTGAAG
Mflv_5091|M.gilvum_PYR-GCK          QGGKGGDGGAGGKGGDADSMGS-----------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1       QGGQGGDGGTGGTGGDATSMGE-----------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155      HGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG-----AASANG
TH_3810|M.thermoresistible__bu      --RQGEDGEDGTGTG------------------------------IGGRG
MAB_4284c|M.abscessus_ATCC_199      --NAGLAGNAGLAGNAG----------------------------LAGNA
MLBr_01183|M.leprae_Br4923          ---VASNAAAAQLTT--------------------------------EIA
MAV_4827|M.avium_104                SPPVAAPLPAAPPPAAP---------------------------PLPEAP
                                        .     .                                       

Mb3621c|M.bovis_AF2122/97           GLGGSGSDTSEGPVTG-----------------GNGGNGGD---------
Rv3590c|M.tuberculosis_H37Rv        GLGGSGSDTSEGPVTG-----------------GNGGNGGD---------
MMAR_4735|M.marinum_M               GEGGAGGD---GNYVG-----------------GVGGTGGA---------
MUL_4367|M.ulcerans_Agy99           GIGGAGGAGGTGGDSG-----------------GVGGVNGD---------
Mflv_5091|M.gilvum_PYR-GCK          GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1       GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155      AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu      GNGGSSSGTHPMAEDG------------------EHVKALD---------
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAGNAGLAG------------------NAGLAGN---------
MLBr_01183|M.leprae_Br4923          PPAADDVSILLAHFFS----------------------------------
MAV_4827|M.avium_104                PIPAAPPVVPVPVVVP------------------PVPVPVP---------
                                       .                                              

Mb3621c|M.bovis_AF2122/97           -------------GGPGAPGGNGAPGGIGVN-TGTGWA------------
Rv3590c|M.tuberculosis_H37Rv        -------------GGPGAPGGNGAPGGIGVN-TGTGWA------------
MMAR_4735|M.marinum_M               -------------GGVGAVGGDGGRGGDSTTGTVAKLG------------
MUL_4367|M.ulcerans_Agy99           -------------GGAGGGGGRGGDGGSSTSTSGVGGAGGA-GGNGGNAG
Mflv_5091|M.gilvum_PYR-GCK          -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu      -------------GRPGLDGGNGSHGG-----------------------
MAB_4284c|M.abscessus_ATCC_199      -------------AGLAGNAGLAGNAGLAGNAGLAGNAG-----------
MLBr_01183|M.leprae_Br4923          --------------GHGRQYQAHASQG-----------------------
MAV_4827|M.avium_104                -------------VRIPVPDPVSPPQLLAPPRLSVPQPVQP---------
                                                                                      

Mb3621c|M.bovis_AF2122/97           ----YGGNGGNGGDGGAG----------------ARGGDGGNGGNGLALN
Rv3590c|M.tuberculosis_H37Rv        ----YGGNGGNGGDGGAG----------------ARGGDGGNGGNGLALN
MMAR_4735|M.marinum_M               ----VGGTGGTGGAGGAG----------------AAGGNGGDGGSAIADS
MUL_4367|M.ulcerans_Agy99           FGVSAGGTGGSAGDGGAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGAG
Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGGIGGAGSTGGTGG----------TGGTGGTGGTGGTG-GTG
Mvan_1264|M.vanbaalenii_PYR-1       ----TGGTGGIGGAGSTGGTGG----------TGGTGGTGGTGGTG-GTG
MSMEG_0868|M.smegmatis_MC2_155      GQTDTGGNGGRGGDGGTFVNAG----------ANGNGGAGGAGGVSEGEG
TH_3810|M.thermoresistible__bu      ----NGGHGGRGGFLGIG----------------GSGGWGGHGGNGGDTD
MAB_4284c|M.abscessus_ATCC_199      ----LAGNAAVAGNAAVAG--------------NAAVAGNAAVGGVLNTG
MLBr_01183|M.leprae_Br4923          ----ATNHQDLIQSLLTS-----------------SSAYAGT-----ETA
MAV_4827|M.avium_104                ----PVRVPQPPSPPQVGG---------------TVPQSPPQHQTPPGEG
                                                                                      

Mb3621c|M.bovis_AF2122/97           GGNGIGGNGGAG---------------GRGGTG----AAGGNGGIGG-GA
Rv3590c|M.tuberculosis_H37Rv        GGNGIGGNGGAG---------------GRGGTG----AAGGNGGIGG-GA
MMAR_4735|M.marinum_M               NEGGTGGTGGTG---------------GTGGTG----AVGGNGGTGGNGF
MUL_4367|M.ulcerans_Agy99           IDGGAGGAGGTGGAAGFPGGGGTTGAWGTGGAG----GAGGAGGAGDHGG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGKGGTGGTG---------GAGGTG----GDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGKGGTGGTG---------GDGGTG----GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GTGGHGGDGGRGGDGALG---------GNGGTGGVGLGNGGKGGNGGNGG
TH_3810|M.thermoresistible__bu      ADGGNGGDGGNG---------------GSAGRG-------GTGGLRG---
MAB_4284c|M.abscessus_ATCC_199      VSGAIGGSSHVG---------------GAINES-----LGGSGSVGGSTA
MLBr_01183|M.leprae_Br4923          NHDSL---------------------------------------------
MAV_4827|M.avium_104                TPPKPDGPGNYGG--------------GHVPTP----GAGGSGGSGGGHV
                                                                                      

Mb3621c|M.bovis_AF2122/97           TGTLT--------------------------FFGSGGDGGPGGAG-----
Rv3590c|M.tuberculosis_H37Rv        TGTLT--------------------------FFGSGGDGGPGGAG-----
MMAR_4735|M.marinum_M               VG-------------------------------GAGGSGGSGGVG-----
MUL_4367|M.ulcerans_Agy99           VGVNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGA
Mflv_5091|M.gilvum_PYR-GCK          TG-------------------------------GTGGTGGTGGAG-----
Mvan_1264|M.vanbaalenii_PYR-1       TG-------------------------------GTGGTGGTGGAG-----
MSMEG_0868|M.smegmatis_MC2_155      NGGTYVDPS----------------------HTGAGGNGGNGGAGR----
TH_3810|M.thermoresistible__bu      ---------------------------------VFGINGGNGRAG-----
MAB_4284c|M.abscessus_ATCC_199      VG-------------------------------GGAHTGVGGGVS-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PTP------------------------------GAGGSGGSGGGHVP---
                                                                                      

Mb3621c|M.bovis_AF2122/97           ----------------------------------------ANTAGTGGVG
Rv3590c|M.tuberculosis_H37Rv        ----------------------------------------ANTAGTGGVG
MMAR_4735|M.marinum_M               ----------------------------------------AAGDG-GGAG
MUL_4367|M.ulcerans_Agy99           GASGIGAGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGAAGSAGDGGAG
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------------DGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------------DGLGGTG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------IRVNNGTATGTATGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------TGVGVGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           GVGGAG---GQGGLLFGD--------------------GGNGGAGG-AGG
Rv3590c|M.tuberculosis_H37Rv        GVGGAG---GQGGLLFGD--------------------GGNGGAGG-AGG
MMAR_4735|M.marinum_M               GVGGAG---GHGGLLFGD--------------------GGAGGSGG-GGA
MUL_4367|M.ulcerans_Agy99           GAGGAGD-DGSAGVVSGDPG----------------TAGKAGGAGG-AGG
Mflv_5091|M.gilvum_PYR-GCK          GTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-LGG
Mvan_1264|M.vanbaalenii_PYR-1       GTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-LGG
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGA
TH_3810|M.thermoresistible__bu      ----------------------------------------LGGRGX----
MAB_4284c|M.abscessus_ATCC_199      HVGG-----GISESLGGSGS-----------------VGGSTAVGG--GA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------TPGTGGPGG----
                                                                                      

Mb3621c|M.bovis_AF2122/97           IGGTG-----------------------ASGGAGGKGGSG---------L
Rv3590c|M.tuberculosis_H37Rv        IGGTG-----------------------ASGGAGGKGGSG---------L
MMAR_4735|M.marinum_M               MGGAG-----------------------AAGGQGGTGGTGGDSSAIDDRL
MUL_4367|M.ulcerans_Agy99           VGGNG-----------------------VAGGVNGSGGAGGAGGAGGTGG
Mflv_5091|M.gilvum_PYR-GCK          GGGTG-----------------------GQGGTGGTGGQGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       VGGTG-----------------------GTGGTGGTGGQGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      TNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEA
TH_3810|M.thermoresistible__bu      -XXXG-------------------------GGVG----------------
MAB_4284c|M.abscessus_ATCC_199      HTGVG-------------------------GGVSTGVGVGSHVGGGISES
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TGGSG-------------------------GGHVPTPGAGTP--------
                                                                                      

Mb3621c|M.bovis_AF2122/97           VG----------GDGGNGGAGGAGGNGGKGG---------AGGAGGGAGM
Rv3590c|M.tuberculosis_H37Rv        VG----------GDGGNGGAGGAGGNGGKGG---------AGGAGGGAGM
MMAR_4735|M.marinum_M               AGNG--------GNGGTGGDGGAGGDGGNGG---------NGGAGGAGGL
MUL_4367|M.ulcerans_Agy99           AGASGVPASVDGGDGGAGGAGGAAGTGGSGGSAGNTGAGGAGGAGGAGGS
Mflv_5091|M.gilvum_PYR-GCK          TG----------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       TG----------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG
MSMEG_0868|M.smegmatis_MC2_155      NGPSAVASGI--GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGT
TH_3810|M.thermoresistible__bu      -------------AAVRSGNGVFSGGGGTPS----------AGFGVPTTI
MAB_4284c|M.abscessus_ATCC_199      LG----------GSGSVGGSTAVGGGAHTGVG---------GGVNTGVGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------GGSGGGHLPFPGAGSTPG------------GSGGGHL
                                                                                      

Mb3621c|M.bovis_AF2122/97           FSQPGVHGAGGTGGQG--------------------GAGGAGGAGGAAGA
Rv3590c|M.tuberculosis_H37Rv        FSQPGVHGAGGTGGQG--------------------GAGGAGGAGGAAGA
MMAR_4735|M.marinum_M               FGHTGASGAGGSAGTG--------------------GAGGNPGAGGDGGS
MUL_4367|M.ulcerans_Agy99           AASTGVNGDGGAGGAGGVGG----LGGDSAATAGGGGAGGDGGKGGAGGA
Mflv_5091|M.gilvum_PYR-GCK          AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN
TH_3810|M.thermoresistible__bu      QFPAGSCTSRAVSREG----------------------IMPSSRAASARA
MAB_4284c|M.abscessus_ATCC_199      GSHVGGGISESLGGSG--------------------SVGGSTAVGGGAHT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PTPGAGTPGGGLGGFGG-----------------GHAPAPGGGLGGGGGH
                                                                                      

Mb3621c|M.bovis_AF2122/97           GTVVAGN-------PGDPG-GFGAAGADGLPG------------------
Rv3590c|M.tuberculosis_H37Rv        GTVVAGN-------PGDPG-GFGAAGADGLPG------------------
MMAR_4735|M.marinum_M               AVIMPGI-------SGADG-RLGDAGADGVAGLSG---------------
MUL_4367|M.ulcerans_Agy99           GVNGVGGGDGGKGGTGGAG-GAGGAGSDGIIPSNGGLGGNGGNGGNGGQA
Mflv_5091|M.gilvum_PYR-GCK          GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155      GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA
TH_3810|M.thermoresistible__bu      GAACASS-------TSRSRRSFCCSRA-----------------------
MAB_4284c|M.abscessus_ATCC_199      SAINDALG-----GSGSVGGSTAVGGGAHTSAINESMNSS----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                APAPGGG-------LGGFGGGHSGGGLGGLGGGHK---------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4735|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           FGDGVGGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGATEDGVGGVG
Mflv_5091|M.gilvum_PYR-GCK          ------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------
Mvan_1264|M.vanbaalenii_PYR-1       ------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------
MSMEG_0868|M.smegmatis_MC2_155      AIHGA-ITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------INASHSSSMNESFGSSMGSHGAAGTGFEAQG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4735|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           CAGGAGGNGGRGDMLFTVGGSGGTGGDGGGGGSASGSGTGGSGGTGGVGG
Mflv_5091|M.gilvum_PYR-GCK          -AAGEDGDAGSGGSG-INGGAGGAGG------------AGGEGGEGGDGG
Mvan_1264|M.vanbaalenii_PYR-1       -AAGDAGDPGSEAVD-INGGAGGAGG------------AGGEGGEGGAGG
MSMEG_0868|M.smegmatis_MC2_155      AVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS-GGQTADGEHNTGGNGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---HAQGHASETAHTTLPGAEHH---------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           --------------------------------------------------
Rv3590c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4735|M.marinum_M               --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           IGGDGKLGGFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTG-AGGAPSDK
Mflv_5091|M.gilvum_PYR-GCK          KGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1       AGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAG
MSMEG_0868|M.smegmatis_MC2_155      NGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3621c|M.bovis_AF2122/97           -----------
Rv3590c|M.tuberculosis_H37Rv        -----------
MMAR_4735|M.marinum_M               -----------
MUL_4367|M.ulcerans_Agy99           GINGEPGNPG-
Mflv_5091|M.gilvum_PYR-GCK          GSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       GSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      GTAGTTGANNP
TH_3810|M.thermoresistible__bu      -----------
MAB_4284c|M.abscessus_ATCC_199      -----------
MLBr_01183|M.leprae_Br4923          -----------
MAV_4827|M.avium_104                -----------