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EYLIAAQDVLVAAAADLEGIGSALAAANRAAEAPTTGLLAAGADEVSAAIASLFSGNAQAYQALSAQAAA FHQQFVRALSSAAGSYAAAEAANASPMQAVLDVVNGPTQLLLGRPLIGDGANGGPGQNGGDGGLLYGNGG NGGSSSTPGQPGGRGGAAGLIGNGGAGGAGGPGANGGAGGNGGWLYGNGGLGGNGGAATQIGGNGGNGGH GGNAGLWGNGGAGGAGAAGAAGANGQNPVSHQVTHATDGADGTTGPDGNGTDAGSGSNAVNPGVGGGAGG IGGDGTNLGQTDVSGGAGGDGGDGANFASGGAGGNGGAAQSGFGDAVGGNGGAGGNGGAGGGGGLGGAGG SANVANAGNSIGGNGGAGGNGGIGAPGGAGGAGGNANQDNPPGGNSTGGNGGAGGDGGVGASADVGGAGG FGGSGGRGGLLLGTGGAGGDGGVGGDGGIGAQGGSGGNGGNGGIGADGMANQDGDGGDGGNGGDGGAGGA GGVGGNGGTGGAGGLFGQSGSPGSGAAGGLGGAGGNGGAGGGGGTGFNPGAPGDPGTQGATGANGQHGLN G*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1243c | PE_PGRS23 | - | 100% (562) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | e-173 | 54.45% (641) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3590c | PE_PGRS58 | e-173 | 54.83% (600) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1275c | PE_PGRS23 | 0.0 | 100.00% (562) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-111 | 46.48% (525) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 1e-13 | 40.22% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-51 | 38.52% (405) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4149 | - | 1e-171 | 54.77% (608) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-21 | 41.45% (193) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-86 | 37.44% (601) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 38.96% (326) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-150 | 51.57% (605) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-108 | 44.70% (557) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4149|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------MEYLIAAQDVLVAAAADLEGIG--------
Mb1275c|M.bovis_AF2122/97 --------------------MEYLIAAQDVLVAAAADLEGIG--------
MMAR_4149|M.marinum_M --------------------MSFVVVSPEVLAVAGRDLASIG--------
MUL_3292|M.ulcerans_Agy99 --------------------MSYVIAAPEMLAGAATDLAGIG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG-
MAV_4827|M.avium_104 ----------------MNIVLGVSMAPSSIQMVVLEGEYADG--------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv -------------------------------------SALAAANRAAEAP
Mb1275c|M.bovis_AF2122/97 -------------------------------------SALAAANRAAEAP
MMAR_4149|M.marinum_M -------------------------------------SAISQANVAAAAP
MUL_3292|M.ulcerans_Agy99 -------------------------------------AALQSANGAAAAP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LSAVSAAQVGAVMP
MAV_4827|M.avium_104 -------------------------------------ATVEEDAIDVTGA
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------------------------TTGLLAAGADEV
Mb1275c|M.bovis_AF2122/97 --------------------------------------TTGLLAAGADEV
MMAR_4149|M.marinum_M --------------------------------------TMGALAAGADEV
MUL_3292|M.ulcerans_Agy99 --------------------------------------ITGVLAAGADEI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------VVAESVASNYGYQ
MAV_4827|M.avium_104 D--------------------------------------DAATASAPDRV
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv S--------------------------------------AAIASLFSGNA
Mb1275c|M.bovis_AF2122/97 S--------------------------------------AAIASLFSGNA
MMAR_4149|M.marinum_M S--------------------------------------AAVAAVFSGHA
MUL_3292|M.ulcerans_Agy99 S--------------------------------------AAVAALFSGHA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SQWVN---------------------------------TGNPIHDLSGNL
MAV_4827|M.avium_104 IS--------------------------------------AILGTREGAA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
Rv1243c|M.tuberculosis_H37Rv QAY------QALSAQAAAFHQQFVRALSSAAGSYAAAEAANASPMQAV--
Mb1275c|M.bovis_AF2122/97 QAY------QALSAQAAAFHQQFVRALSSAAGSYAAAEAANASPMQAV--
MMAR_4149|M.marinum_M QAY------QALGAQVAAFHDQLVTALDAAAGKYASAEVANASPLQAV--
MUL_3292|M.ulcerans_Agy99 LDY------QALSTQMAGFHQQFVTALNSAGASYAAAEAASANPLQAVEQ
MLBr_01183|M.leprae_Br4923 ---------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQ
MAB_4284c|M.abscessus_ATCC_199 QNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPS
MAV_4827|M.avium_104 DAG-----LQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGG--NAGAF--ALFGNGGNG--GNGGVGVVGATGAVG--APGV
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGG--DAGLF--SLFGRGGNG--GNGGVGIAGATGAVG--APGV
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGG--SGG----LLMGIGGAG--GAGGVGADGTSAHVDGGTGGT
TH_3810|M.thermoresistible__bu LGGNGGHGG--GTGII--SLLSLAGNG--GNGGNGYR-------------
Rv1243c|M.tuberculosis_H37Rv --LDVVNGP--TQLLLGRPLIGDGANG--GPGQNGGDGGLLYGN------
Mb1275c|M.bovis_AF2122/97 --LDVVNGP--TQLLLGRPLIGDGANG--GPGQNGGDGGLLYGN------
MMAR_4149|M.marinum_M --LDVVNAP--AQALLGRPLIGNGDDGVAGTGQSGGDGGILYGN------
MUL_3292|M.ulcerans_Agy99 QLLGVINAP--TQALLGRPLIGDGTAG--APGQNGGDGGLLWGN------
MLBr_01183|M.leprae_Br4923 LTTEIAPPA--ADDVS--ILLAHFFSG-----------------------
MAB_4284c|M.abscessus_ATCC_199 GNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGS
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIR----A
Mflv_5091|M.gilvum_PYR-GCK AGATGATGVTSGVVGGNGEDAVGYGATGAAGAA-GAAGAAGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGATGVTSNVTGGNGADAVGYGATGAAGAA-GAAGAAGKAG------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAA-GAAGNGGDGGNGGFGY
TH_3810|M.thermoresistible__bu ---TTDNNALDGGHGGNGGNVGFFSLFNLGGAG-GWGGSGVDG-------
Rv1243c|M.tuberculosis_H37Rv -GGNGGSSSTPGQPGGRGGAAGLIGNGGAGGAG-GPGANGGAGG------
Mb1275c|M.bovis_AF2122/97 -GGNGGSSSTPGQPGGRGGAAGLIGNGGAGGAG-GPGANGGAGG------
MMAR_4149|M.marinum_M -GGDGGSGAS-GQIGGTGGSAGLIGAGGTGGAG-GLGAAGGAGG------
MUL_3292|M.ulcerans_Agy99 -GGAGGVGTAAHPTGGSGGSAGLIGTGGAGGAGYGPAAQTGATG------
MLBr_01183|M.leprae_Br4923 ---HGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL------
MAB_4284c|M.abscessus_ATCC_199 TAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS--
MAV_4827|M.avium_104 ESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQ------
. ..
Mflv_5091|M.gilvum_PYR-GCK --------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1 --------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------
MSMEG_0868|M.smegmatis_MC2_155 VLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIG
TH_3810|M.thermoresistible__bu ---------VDVVGGNPDGGTPGAHG--ESHTPGVYTDR-----------
Rv1243c|M.tuberculosis_H37Rv ----------NGGWLYGNGGLGGNGG--AATQIGGNG-------------
Mb1275c|M.bovis_AF2122/97 ----------NGGWLYGNGGLGGNGG--AATQIGGNG-------------
MMAR_4149|M.marinum_M ----------NGGWLFGQGGAGGIGGSGAAGGAGGNGGWLYGD-------
MUL_3292|M.ulcerans_Agy99 ----------GSGGVGGTGGSGLDGP--DSGAAGGAG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------VTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN----------
MAV_4827|M.avium_104 ----------TTTFLDVSVAEEPETALARGAALAAANAPLFAS-------
Mflv_5091|M.gilvum_PYR-GCK ---------AVGAAGAAG------TVGTAGATGGTG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------AIGTAGVAG------AAGTAGATGGTG--------------
MSMEG_0868|M.smegmatis_MC2_155 ANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4149|M.marinum_M -----------GGAGGQG------GAAAESINDGSP--------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------TEI
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTG
Mvan_1264|M.vanbaalenii_PYR-1 -VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTG
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTG
TH_3810|M.thermoresistible__bu -QGEDGEDGTGTGIGGRGGNG-----------------------------
Rv1243c|M.tuberculosis_H37Rv GNGGHGGNAGLWGNGGAGGAG-----------------------------
Mb1275c|M.bovis_AF2122/97 GNGGHGGNAGLWGNGGAGGAG-----------------------------
MMAR_4149|M.marinum_M GQGGNGGSAYLFGNGGSGGQG-----------------------------
MUL_3292|M.ulcerans_Agy99 GSGGSGGAARLFGNGGAGGSG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHNQANIGTSTSAGGSAAVG-----------------------------
MAV_4827|M.avium_104 -STAALAYAQDPGTGAVDQYS-----------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--
Mvan_1264|M.vanbaalenii_PYR-1 GVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--
MSMEG_0868|M.smegmatis_MC2_155 GAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPT
TH_3810|M.thermoresistible__bu -------------------------GSSSGTHPMAEDG------------
Rv1243c|M.tuberculosis_H37Rv -----------------------AAGAAGANGQNPVSH------------
Mb1275c|M.bovis_AF2122/97 -----------------------AAGAAGANGQNPVSH------------
MMAR_4149|M.marinum_M -----------------------GTGLAGADGVNYSNG------------
MUL_3292|M.ulcerans_Agy99 -----------------------GKGGNGGSAIETGND------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------GNAGLAGNAGLAGNAGLAGNAG------------
MAV_4827|M.avium_104 ----------------------LPDYLYVPVDPEPGDD------------
Mflv_5091|M.gilvum_PYR-GCK -----------LQGGKGGDGGAGGKGGDADSMGS----------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------LQGGQGGDGGTGGTGGDATSMGE----------------
MSMEG_0868|M.smegmatis_MC2_155 TGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNG
TH_3810|M.thermoresistible__bu ------------EHVKALDGRPGLDGG-----------------------
Rv1243c|M.tuberculosis_H37Rv ------------QVTHATDGADGTTGP-----------------------
Mb1275c|M.bovis_AF2122/97 ------------QVTHATDGADGTTGP-----------------------
MMAR_4149|M.marinum_M ------------TAGPGAWGNNVTTSIG----------------------
MUL_3292|M.ulcerans_Agy99 ------------GAAGAGGHGGWLVGN-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAGLAGNAG---------------------
MAV_4827|M.avium_104 ------------ELAYSAVGEEDAESPTVVIEKLFLP-------------
Mflv_5091|M.gilvum_PYR-GCK --AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--
Mvan_1264|M.vanbaalenii_PYR-1 --AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--
MSMEG_0868|M.smegmatis_MC2_155 GAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGW
TH_3810|M.thermoresistible__bu -----NGSHGGNGGHGGRGGFLG---------------------------
Rv1243c|M.tuberculosis_H37Rv ---DGNGTDAGSGSNAVNPGVGG---------------------------
Mb1275c|M.bovis_AF2122/97 ---DGNGTDAGSGSNAVNPGVGG---------------------------
MMAR_4149|M.marinum_M ---DANGGNGGSGADGG-AGVTG---------------------------
MUL_3292|M.ulcerans_Agy99 ---GGIGGDGGSGGVGGDAGAYGP------------------PANGGA--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGN--------------------------
MAV_4827|M.avium_104 --EDSEPRRRPVLLVGSGLAVVG---------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------GGTGGAGGAGGTGG-TGGAGGTGG------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------GGTGGNGGNGGTGG-TGGNGGTGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWK
TH_3810|M.thermoresistible__bu -------------------IGGSGGWGGHGGNGGDTDADGGNGG------
Rv1243c|M.tuberculosis_H37Rv ---------------------GAGGIGGDGTNLGQTDVSGGAGG------
Mb1275c|M.bovis_AF2122/97 ---------------------GAGGIGGDGTNLGQTDVSGGAGG------
MMAR_4149|M.marinum_M ---------------------GTGGVGGFANNEGSGDANGGFGG------
MUL_3292|M.ulcerans_Agy99 --------------------GGHGGMGGVGGDAGLLFGSGGAGG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------AGLAGNAGLAGNAGLAGNAGLAGN------
MAV_4827|M.avium_104 ----------------------ISAVLALEIALAIGIRTTGTVALQP---
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 ANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTG
TH_3810|M.thermoresistible__bu ------------------------------------------------DG
Rv1243c|M.tuberculosis_H37Rv -----------------------------DGGDG-------------ANF
Mb1275c|M.bovis_AF2122/97 -----------------------------DGGDG-------------ANF
MMAR_4149|M.marinum_M -----------------------------TGGNGG------------APG
MUL_3292|M.ulcerans_Agy99 -----------------------------VGGNGAIGGTGVMS----GAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------AGLAGNAGLAGNAG--LAGNA
MAV_4827|M.avium_104 ------------------------------TPNQHLIVPTEQAPAPPPVQ
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------G
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------G
MSMEG_0868|M.smegmatis_MC2_155 GHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTG
TH_3810|M.thermoresistible__bu GNGGSAGRGGTGGLRGVFGIN-----------------------------
Rv1243c|M.tuberculosis_H37Rv ASGGAGGNGGAAQSGFGDAVG----------------------------G
Mb1275c|M.bovis_AF2122/97 ASGGAGGNGGAAQSGFGDAVG----------------------------G
MMAR_4149|M.marinum_M ASGGEGGTGGVAIASGGNAYG----------------------------G
MUL_3292|M.ulcerans_Agy99 GAGGDGGNGGYAQLIGDGGGG----------------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAG---------------------------N
MAV_4827|M.avium_104 ASAPQPKISVPEPVAAPKPLS-----------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGE
TH_3810|M.thermoresistible__bu ----GGNGRAG-----------------------------LGGRGXXXX-
Rv1243c|M.tuberculosis_H37Rv NGGAGGNGGAG----------------------------GGGGLGGAGG-
Mb1275c|M.bovis_AF2122/97 NGGAGGNGGAG----------------------------GGGGLGGAGG-
MMAR_4149|M.marinum_M SGGTGGNGATG----------------------------ASGGTGGTGG-
MUL_3292|M.ulcerans_Agy99 AGGAGYSASGL----------------------------PPAGIGAPGG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAVAGNAAVAG--------------------------NAAVAGNAAVGG-
MAV_4827|M.avium_104 PPVAAPLPAAP----------------------------PPAAPPLPEAP
Mflv_5091|M.gilvum_PYR-GCK ----------------TGGTGGQGG-LGGGGGTG----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------TGGTGGQGG-LGGVGGTG----------------
MSMEG_0868|M.smegmatis_MC2_155 ALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQ
TH_3810|M.thermoresistible__bu ----------------GGGVG-----------------------------
Rv1243c|M.tuberculosis_H37Rv ----------------SANVANAG------NSIGG---------------
Mb1275c|M.bovis_AF2122/97 ----------------SANVANAG------NSIGG---------------
MMAR_4149|M.marinum_M ----------------TGGDGGHGGLLIGNGGIGG---------------
MUL_3292|M.ulcerans_Agy99 ----------------AGGAGGSGGWLVGNGGAGG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------VLNTGVSGAIGGSSHVGGAINES--------------
MAV_4827|M.avium_104 -------------PIPAAPPVVPVPVVVPPVPVPVPVR------------
Mflv_5091|M.gilvum_PYR-GCK -------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGL
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGL
MSMEG_0868|M.smegmatis_MC2_155 ASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGID
TH_3810|M.thermoresistible__bu ----------------------------------------AAVRSGNGVF
Rv1243c|M.tuberculosis_H37Rv ----------------------------------------NGGAGGNGGI
Mb1275c|M.bovis_AF2122/97 ----------------------------------------NGGAGGNGGI
MMAR_4149|M.marinum_M ----------------------------------------IGGTGGVGGI
MUL_3292|M.ulcerans_Agy99 ----------------------------------------IGGIGASGSF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------LGGSGSVGGS
MAV_4827|M.avium_104 --------------------------------------IPVPDPVSPPQL
Mflv_5091|M.gilvum_PYR-GCK GGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG---
Mvan_1264|M.vanbaalenii_PYR-1 GGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG---
MSMEG_0868|M.smegmatis_MC2_155 GGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSW
TH_3810|M.thermoresistible__bu SGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS--------
Rv1243c|M.tuberculosis_H37Rv GAPGGAGGAGGN-ANQDNPPGGNSTGGNGGAGGDGGVGASADVGGAG---
Mb1275c|M.bovis_AF2122/97 GAPGGAGGAGGN-ANQDNPPGGNSTGGNGGAGGDGGVGASADVGGAG---
MMAR_4149|M.marinum_M GGTGGDGGTGGVGGSALNTGSGVADANIGGDGGDAGTGGDGGTGGVG---
MUL_3292|M.ulcerans_Agy99 GAPSGQGGNGGIGGAAGLFGQG----GAGGNGGQGGGDDFALSGGAG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG---
MAV_4827|M.avium_104 LAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP---
Mflv_5091|M.gilvum_PYR-GCK -GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATG
Mvan_1264|M.vanbaalenii_PYR-1 -GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATG
MSMEG_0868|M.smegmatis_MC2_155 VQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATG
TH_3810|M.thermoresistible__bu ------ARAGAACASSTSRSRRSFCCSRA---------------------
Rv1243c|M.tuberculosis_H37Rv ------GFGGSGGRGGLLLGTGGAGGDGGVGGDG------GIGAQGGSGG
Mb1275c|M.bovis_AF2122/97 ------GFGGSGGRGGLLLGTGGAGGDGGVGGDG------GIGAQGGSGG
MMAR_4149|M.marinum_M ------GVGGSGGAGGLLFGN---GGDGGAGGDG------GVGGTGGIGG
MUL_3292|M.ulcerans_Agy99 ------GAGGAGGHGGQLYGDGGGGGAGGMGGSV------DIAESGVTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GAHTGVGGGVSTGVGVGSHVGGGISESLGGSG------SVGGSTAVGG
MAV_4827|M.avium_104 -----PKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP----TPGAGGSGGS
Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGAN
Mvan_1264|M.vanbaalenii_PYR-1 ASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGAN
MSMEG_0868|M.smegmatis_MC2_155 NTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv NGGNGGIGA-DGMANQDGDGG-------------------------DGGN
Mb1275c|M.bovis_AF2122/97 NGGNGGIGA-DGMANQDGDGG-------------------------DGGN
MMAR_4149|M.marinum_M AGGNGGVGG-DGSSSGTGAGG-------------------------SGGD
MUL_3292|M.ulcerans_Agy99 RGGSGSVGGGAGLWGAGGQGG-------------------------DGAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTGVGGGVNTGVGVGSHVG-------------------------GGIS
MAV_4827|M.avium_104 GGGHVPTPGTGGPGGTGGSGG---------------------GHVPTPGA
Mflv_5091|M.gilvum_PYR-GCK GSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1 GSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGA
MSMEG_0868|M.smegmatis_MC2_155 GGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv GGDGGAGGAG----------------GVGGNGGTGGAGG----LFGQSGS
Mb1275c|M.bovis_AF2122/97 GGDGGAGGAG----------------GVGGNGGTGGAGG----LFGQSGS
MMAR_4149|M.marinum_M ATDGGTGGDG----------------GSGGGFGTGGAGGTGGWLIGHSGT
MUL_3292|M.ulcerans_Agy99 GGDGGAGVDTTT--------------GAGGDGGAGAGGGTSGFLYGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVG----------------GSTAVGGGAHTSAINDALGGSGSV
MAV_4827|M.avium_104 GTPGGSGGGHLP---------------FPGAGSTPGGSGGGHLPTPGAGT
Mflv_5091|M.gilvum_PYR-GCK GG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAG
MSMEG_0868|M.smegmatis_MC2_155 GGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv P--------------------GSGAAG-----------GLGGAGGNGGAG
Mb1275c|M.bovis_AF2122/97 P--------------------GSGAAG-----------GLGGAGGNGGAG
MMAR_4149|M.marinum_M NG-----------------IGGTGGAG-----------GAGAVGGDGGVG
MUL_3292|M.ulcerans_Agy99 GG-----------------AGGHGGGGP----------GMGGDGGDGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GG---------------STAVGGGAHTSAINESMNSSINASHSSSMNESF
MAV_4827|M.avium_104 PG------------------GGLGGFGG----------GHAPAPGGGLGG
Mflv_5091|M.gilvum_PYR-GCK GSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD---------
Mvan_1264|M.vanbaalenii_PYR-1 GSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD----------
MSMEG_0868|M.smegmatis_MC2_155 GTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP---------
TH_3810|M.thermoresistible__bu ---------------------------------------------
Rv1243c|M.tuberculosis_H37Rv G----GGGTGFNPGAPGDPGTQGATGANGQHGLNG----------
Mb1275c|M.bovis_AF2122/97 G----GGGTGFNPGAPGDPGTQGATGANGQHGLNG----------
MMAR_4149|M.marinum_M GDP--GVGTTYN-GISGHNGVQGGTGADGAAG-------------
MUL_3292|M.ulcerans_Agy99 GRAQ-LIGTGGNGGAGGTAAPGGTDGTAGAAGKGGVLFGTDGATG
MLBr_01183|M.leprae_Br4923 ---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-------
MAV_4827|M.avium_104 GGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------------