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MLYVVASPDLMTAAATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQIAALFGAHARSYQTLSTQAA AFHSRFVQALTTAAASYASVEAANASPLQVALDVINAPAQTLLGRPLIGNGADGSTPGQAGGPGGLLYGN GGNGAAGGPNQAGGAGGNAGLIGNGGAGGAGGVGAVGGNGGTGGLLFGNGGAGGQGGLGLAGINGGSGGQ GGHGGNAILFGQGGAGGPGGTGAMGVAGTNPTPIGTAAPGSDGVNQIGNGGNTDLTGGAGGDGNAGSTTV NGGNGGTGGAARNSSGGTGNSFGGAGGAGGDGANGGDGGAGGEALTEGGATAVSGAGGKGGNAEASGGAG GNGGKGGFAQATTSVTGGNGGNGGNGHDSNAPGGAGGSGGVGGDGGRGGLLAGNGGTGGAGGNGGTGGAG APGGAGGAGGKADIANSLGDNATVTGGNGGTGGDGGSALGTGGAGGAGGLGGHGGAGGLLIGNGGAGGAG GLGGAGGAGGAGGEGGAGGAGGEAIPGGASTNSAGGDGGAGGTGGNGGDGGAGGAPGLGGAGGAGGWLIG QSGSTGGGGAGGAGGAGGAGGAGGSGGAGGHGDTTSGKNGSSGTAGFDGNPGQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | - | 100% (615) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0896c | PE_PGRS15 | 0.0 | 65.11% (622) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | e-174 | 52.31% (694) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-122 | 47.12% (573) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2853 | PE_PGRS48 | 0.0 | 99.67% (615) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-14 | 39.18% (97) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-44 | 32.84% (539) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2490 | - | 0.0 | 59.46% (624) | PE-PGRS family protein, PE_PGRS15_1 |
| M. avium 104 | MAV_4827 | - | 8e-24 | 43.27% (171) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-99 | 38.11% (732) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-45 | 42.26% (310) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 1e-159 | 49.71% (700) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-117 | 46.02% (591) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2490|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2490|M.marinum_M --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 ------------------------------------MLYVVASPDLMTAA
Rv2853|M.tuberculosis_H37Rv ------------------------------------MLYVVASPDLMTAA
MMAR_2490|M.marinum_M ------------------------------------MSFVITAPELISAA
MUL_0572|M.ulcerans_Agy99 ------------------------------------MSYVVAIPDMLASA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
Mb2878|M.bovis_AF2122/97 ATNLAEIG-----------------SAISTANGAAALPTVEVVAAAADEV
Rv2853|M.tuberculosis_H37Rv ATNLAEIG-----------------SAISTANGAAALPTVEVVAAAADEV
MMAR_2490|M.marinum_M ATDLAGIG-----------------STISAANAAASASTTAVAAAAADEV
MUL_0572|M.ulcerans_Agy99 AADVAGIG-----------------SSVGAANTAAVGATTGVMAAADDEV
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VEAASYVADP---------------------EAALANAGLSAVSAAQVGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 IQMVVLEG--------------------EYADGATVEEDAIDVTGADDAA
Mb2878|M.bovis_AF2122/97 STQIAALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASP
Rv2853|M.tuberculosis_H37Rv STQIAALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASP
MMAR_2490|M.marinum_M STAVATLFGAHAQQYQSLGSQMAAFHDDFVRILASGSNLYATAEATNASP
MUL_0572|M.ulcerans_Agy99 SVAIAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAANASP
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR
Mb2878|M.bovis_AF2122/97 LQV----ALDVINAPAQTLLGRPLIGNGADGST-PGQAGGPGGLLYGNGG
Rv2853|M.tuberculosis_H37Rv LQV----ALDVINAPAQTLLGRPLIGNGADGST-PGQAGGPGGLLYGNGG
MMAR_2490|M.marinum_M LQP----LLDLINAPTQAILGRPLIGNGSNGTY-PGQDGRDGGLLIGNGG
MUL_0572|M.ulcerans_Agy99 LQAAEQEVLAVINAPTNALLGRPLIGNGTDGLAGTGAAGGAGGLLWGNGG
Mflv_5091|M.gilvum_PYR-GCK QN-------------GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-------------GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGG
MSMEG_0868|M.smegmatis_MC2_155 DNP--------NGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG
MLBr_01183|M.leprae_Br4923 ---------------MPLFLNAEPQALTAAANTLEGLS---AATVASNAA
MAV_4827|M.avium_104 IDN-------------VMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPD
Mb2878|M.bovis_AF2122/97 NGAAGGPNQAGGAGGNAG---LIGNGGAGGAGGVG-------------AV
Rv2853|M.tuberculosis_H37Rv NGAAGGPNQAGGAGGNAG---LIGNGGAGGAGGVG-------------AV
MMAR_2490|M.marinum_M NGAAGDFGQAGGGGGSAG---LFGDGGNGGTGGAG-------------SA
MUL_0572|M.ulcerans_Agy99 NGGSGAAGQAGGAGGAAG---LIGTGGAGGMGGAGG------------GA
Mflv_5091|M.gilvum_PYR-GCK NGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGV
Mvan_1264|M.vanbaalenii_PYR-1 NGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGV
MSMEG_0868|M.smegmatis_MC2_155 NGGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGT
TH_3810|M.thermoresistible__bu ------VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GN
MAB_4284c|M.abscessus_ATCC_199 DLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADH
MLBr_01183|M.leprae_Br4923 AAQLT-TEIAPPAADDVS---ILLAHFFSGHGRQY-------------QA
MAV_4827|M.avium_104 TATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLS------------AMV
.. *
Mb2878|M.bovis_AF2122/97 GGNGGTGGLLFG-----------------NGGAGGQGGLGLAG-------
Rv2853|M.tuberculosis_H37Rv GGKRGTGGLLFG-----------------NGGAGGQGGLGLAG-------
MMAR_2490|M.marinum_M GGNGGTGGLLFG-----------------NGGNGGMGGTATLG-------
MUL_0572|M.ulcerans_Agy99 GGMGGSGGWLLG-----------------NGGAGGAGGVGCAG-------
Mflv_5091|M.gilvum_PYR-GCK AGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYV
TH_3810|M.thermoresistible__bu GGHGGGTGIIS--------------------LLSLAGNGGNGG-------
MAB_4284c|M.abscessus_ATCC_199 GSNVGVDQSQTR----------------VGGDYTNVSGHGSAD-------
MLBr_01183|M.leprae_Br4923 HASQGAT-----------------------NHQDLIQSLLTSS-------
MAV_4827|M.avium_104 AGLEKLESLPGG-----------------LLLVGSGVDVAPLK-------
.
Mb2878|M.bovis_AF2122/97 ------------INGGSGGQGGHGG--NAILFGQGGAGGPGG--------
Rv2853|M.tuberculosis_H37Rv ------------INGGSGGQGGHGG--NAILFGQGGAGGPGG--------
MMAR_2490|M.marinum_M ------------FNGGMAGAGGNGG--SALLFGSGGAGGQGG--------
MUL_0572|M.ulcerans_Agy99 ------------VSGG---VGGTGG--NAMLFGNGGAGGMGG--------
Mflv_5091|M.gilvum_PYR-GCK -------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGA
Mvan_1264|M.vanbaalenii_PYR-1 -------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGT
MSMEG_0868|M.smegmatis_MC2_155 LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------IDKSVTVVDDHSQRNTTNINDSFNTDRSTN--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------QVLQTTTFLDVSVAEEPETALARGAALAAAN--------
Mb2878|M.bovis_AF2122/97 ----------TGAMGVAGTNPTPIGTAAPGSDG--------------VNQ
Rv2853|M.tuberculosis_H37Rv ----------TGAMGVAGTNPTPIGTAAPGSDG--------------VNQ
MMAR_2490|M.marinum_M ----------TGVAGTNGSNPLVFDTANPGAAGQD------------VTT
MUL_0572|M.ulcerans_Agy99 ----------AGADGAVGAAGTAGTSTSAGGVGGAGW---DATAAGVLAA
Mflv_5091|M.gilvum_PYR-GCK AG-------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGA
Mvan_1264|M.vanbaalenii_PYR-1 AG-------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGA
MSMEG_0868|M.smegmatis_MC2_155 NGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTA
TH_3810|M.thermoresistible__bu ----------------NGYRTTDNNALDGGHGGNG---------------
MAB_4284c|M.abscessus_ATCC_199 ----------IGSGNTTNTEIGSHNQANIGTSTSAGG----------SAA
MLBr_01183|M.leprae_Br4923 -------------SAYAGTETANHDSL-----------------------
MAV_4827|M.avium_104 ------------APLFASSTAALAYAQDPGTGAVDQYS---LPDYLYVPV
.
Mb2878|M.bovis_AF2122/97 IGNGGNTDLTGGAGGDGNAG--------------------STTVNGGNGG
Rv2853|M.tuberculosis_H37Rv IGNGGNTDLTGGAGGDGNAG--------------------STTVNGGNGG
MMAR_2490|M.marinum_M TDDPAANPLTGGNGSEGAAG--------------------STIQNGGVGG
MUL_0572|M.ulcerans_Agy99 TGGDGGDSGGGGAGGNGGAGGAGGHG-------SALFGADGANGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK AGGAGGLGETGTTGGAGGVG--------------------GQGTAGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGTAGETGVTGGVGGIG--------------------GQGTEGGTGG
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGG
TH_3810|M.thermoresistible__bu --GNVGFFSLFNLGGAGGWG--------------------GSGVDG----
MAB_4284c|M.abscessus_ATCC_199 VGGNAGLAGNAGLAGNAGLAG-------------------NAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DPEPGDDELAYSAVGEEDAESP------------------TVVIEKLFLP
Mb2878|M.bovis_AF2122/97 TGG----------------AARNS--------------------------
Rv2853|M.tuberculosis_H37Rv TGG----------------AARNS--------------------------
MMAR_2490|M.marinum_M QGG----------------SATST--------------------------
MUL_0572|M.ulcerans_Agy99 AGGNPGAPGNGGTGGVGPDAATSGGMG-----------------------
Mflv_5091|M.gilvum_PYR-GCK VGGIGGAG----------STGAVGG-------VGGKG----IQGGQG---
Mvan_1264|M.vanbaalenii_PYR-1 VGGVGGVG----------ATGGAGG-------VGGKG----IQGGQG---
MSMEG_0868|M.smegmatis_MC2_155 AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT
TH_3810|M.thermoresistible__bu -------------------VDVVGG-------------------------
MAB_4284c|M.abscessus_ATCC_199 AGN----------------AGLAGN-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EDS----------------EPRRRP-------------------------
Mb2878|M.bovis_AF2122/97 ----------SGGTGNSFGGAGGAGGDG----------------------
Rv2853|M.tuberculosis_H37Rv ----------SGGTGNSFGGAGGAGGDG----------------------
MMAR_2490|M.marinum_M ----------NQNS--ALGGEGGKGGDG----------------------
MUL_0572|M.ulcerans_Agy99 ---------GTGGDPGAVGGRGNSGAAGGAGAVAG--------ASGAAGT
Mflv_5091|M.gilvum_PYR-GCK ----------LQGGKGGDGGAGGKGGDADSMGS-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------LQGGQGGDGGTGGTGGDATSMGE-----------------
MSMEG_0868|M.smegmatis_MC2_155 GGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG
TH_3810|M.thermoresistible__bu ---------------NPDGGTPG---------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAG----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------VLLVGSGLAVVGISAVLALEIALAIG----------------
Mb2878|M.bovis_AF2122/97 ---ANGGDGGAGGEALTEGG------------------------------
Rv2853|M.tuberculosis_H37Rv ---ANGGDGGAGGEALTEGG------------------------------
MMAR_2490|M.marinum_M ---ANGGMGGNGGSGDTSGQTD----------------------------
MUL_0572|M.ulcerans_Agy99 IIAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHGG--------------
Mflv_5091|M.gilvum_PYR-GCK -AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD---
Mvan_1264|M.vanbaalenii_PYR-1 -AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN---
MSMEG_0868|M.smegmatis_MC2_155 AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV
TH_3810|M.thermoresistible__bu ---AHGESHTPGVYTDRQ--------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAG----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --IRTTGTVALQPTPNQHLIVP----------------------------
Mb2878|M.bovis_AF2122/97 ------------------ATAVSGAGGKGGNAEASGGAGGNGG-------
Rv2853|M.tuberculosis_H37Rv ------------------ATAVSGAGGKGGNAEASGGAGGNGG-------
MMAR_2490|M.marinum_M ---------------APQPSATGGNGGNGGDAQVAGGAGGAGG-------
MUL_0572|M.ulcerans_Agy99 ---------------AGGFYGNGGAGGAGGNSAPGGGTGGNGG-------
Mflv_5091|M.gilvum_PYR-GCK -------------------GGTGGAGGAGGTGG-TGGAGGTGG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGTGGNGGNGGTGG-TGGNGGTGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKA
TH_3810|M.thermoresistible__bu -----------------------GEDGEDGTGTGIGGRGGNGG-------
MAB_4284c|M.abscessus_ATCC_199 ------------------NAGLAGNAGLAGNAGLAGNAGLAGN-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------TEQAPAPPPVQASAPQPKISVPEP-------
Mb2878|M.bovis_AF2122/97 ---------KGGFAQATTS-----------VTGGNGGNGGNGHDS---NA
Rv2853|M.tuberculosis_H37Rv ---------KGGFAQATTS-----------VTGGNGGNGGNGHDS---NA
MMAR_2490|M.marinum_M ---------WGGDGHANQGD----------AVGGVGGRGGAGFAS---SA
MUL_0572|M.ulcerans_Agy99 ---------TGGDSGAMGSSGGRGGDGGVGTNGGAGGGGGNATSYGTANA
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 NGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGG
TH_3810|M.thermoresistible__bu ---------SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGS
MAB_4284c|M.abscessus_ATCC_199 --------AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVP
Mb2878|M.bovis_AF2122/97 PGGAGGSGGVG--------GDGGRG-----------------------GL
Rv2853|M.tuberculosis_H37Rv PGGAGGSGGVG--------GDGGRG-----------------------GL
MMAR_2490|M.marinum_M AGGAGGTGGTG--------GQGGNG-----------------------GL
MUL_0572|M.ulcerans_Agy99 TGGAGGDGGTGSTGNGGSGGDGGNGGTGHGGGGGPGGTAINYGAGDAFGG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGKGGTG-----GTGGAGGTG------------------GDGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGKGGTG-----GTGGDGGTG------------------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 HGGDGGRGGDG-----ALGGNGGTGGVGL--------------GNGGKGG
TH_3810|M.thermoresistible__bu HGGNGGHGGRG-----GFLGIGGSG---------------------GWGG
MAB_4284c|M.abscessus_ATCC_199 AAVAGNAAVGG------VLNTGVSG---------------------AIGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPVVVPPVPVPVPVRIPVPDPVSPP-----------------------QL
Mb2878|M.bovis_AF2122/97 LAGNGGTG---------GAGGNGGTGGAG------------APGGAGGAG
Rv2853|M.tuberculosis_H37Rv LAGNGGTG---------GAGGNGGTGGAG------------APGGAGGAG
MMAR_2490|M.marinum_M LFGNGGTG---------GVGGTGGMGGAG------------AAGGTGGDG
MUL_0572|M.ulcerans_Agy99 AAGKGGTG---------VVGGNGGSGGAAY---NYGTGNATGAGGSSGSG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG---------GTGGTGGTGGAG-----------DGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG---------GTGGTGGTGGAG-----------DGLGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNG
TH_3810|M.thermoresistible__bu HGGNGGD-----------TDADGGNGGDG---------------GNGGSA
MAB_4284c|M.abscessus_ATCC_199 SSHVGGAIN-------ESLGGSGSVGGST------------AVGGGAHTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LAPPRLSVP-------QPVQPPVRVPQPP------------SPPQVGGTV
Mb2878|M.bovis_AF2122/97 GKADIANSLGDNATVTG----------------GNGGTGGDGGS------
Rv2853|M.tuberculosis_H37Rv GKADIANSLGDNATVTG----------------GNGGTGGDGGS------
MMAR_2490|M.marinum_M GNAGFAIG-GSDGTATG----------------QQGGDGGYGAD------
MUL_0572|M.ulcerans_Agy99 GAASVPNS-ASTATATS----------------GSGGAGGDGTDGGNGGS
Mflv_5091|M.gilvum_PYR-GCK G----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGG
Mvan_1264|M.vanbaalenii_PYR-1 G----TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGG
MSMEG_0868|M.smegmatis_MC2_155 GNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNG
TH_3810|M.thermoresistible__bu G---------------------------------RGGTGGLRGVFGINGG
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVGVGSHVGGG---------------ISESLGGSGS-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PQSPPQHQTPPGEGTPP----------------KPDGPGNYGGGHVP---
Mb2878|M.bovis_AF2122/97 -----------------------ALGTGGAGGAGG-------------LG
Rv2853|M.tuberculosis_H37Rv -----------------------ALGTGGAGGAGG-------------LG
MMAR_2490|M.marinum_M -----------------------STAVGGTGGAGG-------------TG
MUL_0572|M.ulcerans_Agy99 GGFAFTFGTGNIIAGVGGGGGTGSTGVGGIGGSGGGADINNGAFTVVPQG
Mflv_5091|M.gilvum_PYR-GCK TG-----------------------GQGGTGGTGG-------------QG
Mvan_1264|M.vanbaalenii_PYR-1 TG-----------------------GTGGTGGTGG-------------QG
MSMEG_0868|M.smegmatis_MC2_155 TGGAATIVAYNVVQANPQASGTATDGHGGSGINGG-------------HG
TH_3810|M.thermoresistible__bu NG------------------------RAGLGGRGX-------------XX
MAB_4284c|M.abscessus_ATCC_199 --------------------------VGGSTAVGG--------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------TPGAGGSGGSGGG------------HV
Mb2878|M.bovis_AF2122/97 GHGGAGGLLIGN-------------GGAGGAGG-------------LGGA
Rv2853|M.tuberculosis_H37Rv GHGGAGGLLIGN-------------GGAGGAGG-------------LGGA
MMAR_2490|M.marinum_M GNGGNGGWLIGS-------------GGAGGVSG-------------TGGV
MUL_0572|M.ulcerans_Agy99 GAGGHGGDGATD-------------GGAGGAGGFTEIDSSASVIAATGGA
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG--------GTGGAGGDGGLGG-------------LGGF
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG--------GTGGAGGDGGLGG-------------LGGF
MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAVASGIGAGGNGGDGIDGG-------------LGGN
TH_3810|M.thermoresistible__bu XGGGVGAAVRSG---------------NGVFSG-------------GGGT
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTG-------------VGVGSHVG-------------GGIS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PTPGAGGSGGSG-------------GGHVPTPG-------------TGGP
Mb2878|M.bovis_AF2122/97 GGAGGAGGEG----GAGGAGGEAIPGG-----------------------
Rv2853|M.tuberculosis_H37Rv GGAGGAGGEG----GAGGAGGEAIPGG-----------------------
MMAR_2490|M.marinum_M GGTGGAGGAG----GIGGIGGNTSS-------------------------
MUL_0572|M.ulcerans_Agy99 GGDGGSGGTGRGGTGGGGTGGGGTGGGG-------------------GVG
Mflv_5091|M.gilvum_PYR-GCK GGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSA
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSA
MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG
TH_3810|M.thermoresistible__bu PSAGFGVPTTIQFPAGSCTSRAVSREG-----------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAHTGVGGG------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGTGGSGGGHVPTPGAGTPGGSGGGHLP----------------------
Mb2878|M.bovis_AF2122/97 ---ASTNSAGGDGGAGGTGGNGGDGGAGG------------APGLGGAGG
Rv2853|M.tuberculosis_H37Rv ---ASTNSAGGDGGAGGTGGNGGDGGAGG------------APGLGGAGG
MMAR_2490|M.marinum_M ---SSTASVAGEGGHGGDGGDGGDGGNGG------------AAGAVAGAG
MUL_0572|M.ulcerans_Agy99 INNGSGEAIGGAPGAGGTGAVGGDGGQGG------------AAYSYGTGD
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAG
Mvan_1264|M.vanbaalenii_PYR-1 GTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQG
MSMEG_0868|M.smegmatis_MC2_155 STLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGG
TH_3810|M.thermoresistible__bu -IMPSSRAASARAG---------------------------AACASSTSR
MAB_4284c|M.abscessus_ATCC_199 --VNTGVGVGSHVGGGISESLGGSGSVGG------------STAVGGGAH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---FPGAGSTPGGSGGGHLPTPGAGTPGG--------------GLGGFGG
Mb2878|M.bovis_AF2122/97 AGG--WLIGQSGSTG--------------GGGAGGAGGAG----------
Rv2853|M.tuberculosis_H37Rv AGG--WLIGQSGSTG--------------GGGAGGAGGAG----------
MMAR_2490|M.marinum_M GRG--GLIGAAGGTG--------------SIGAGGAAGAG----------
MUL_0572|M.ulcerans_Agy99 ATGSAGAAGTAGTTG--------------VGGTGGAGGAAYTLNGASTAT
Mflv_5091|M.gilvum_PYR-GCK ATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAA
MSMEG_0868|M.smegmatis_MC2_155 DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGAD
TH_3810|M.thermoresistible__bu SRRSFCCSRA----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINDALGGSGSVG----------------GSTAVG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GHAPAPGGGLGGGGG-----------------------------------
Mb2878|M.bovis_AF2122/97 --------------------GAGGAG-------------GSGGAGG----
Rv2853|M.tuberculosis_H37Rv --------------------GAGGAG-------------GSGGAGG----
MMAR_2490|M.marinum_M --------------------GAGGAG-------------GAGGAGGT---
MUL_0572|M.ulcerans_Agy99 ATGGIGGNGGDGGTANGSNGGNGGAGGYASTTGTGTASVGNGGRGGD---
Mflv_5091|M.gilvum_PYR-GCK GKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----
Mvan_1264|M.vanbaalenii_PYR-1 GKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----
MSMEG_0868|M.smegmatis_MC2_155 GWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------GGAHTSAINESMNSSINASHSSSMN---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------HGDTTSGKNGSSG-----------------------------
Rv2853|M.tuberculosis_H37Rv --------HGDTTSGKNGSSG-----------------------------
MMAR_2490|M.marinum_M -------AQGSGASGGTGANG-----------------------------
MUL_0572|M.ulcerans_Agy99 -------GTATVATGGTGGVGGNAHA---------------------PAG
Mflv_5091|M.gilvum_PYR-GCK -------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGG
Mvan_1264|M.vanbaalenii_PYR-1 -------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGG
MSMEG_0868|M.smegmatis_MC2_155 WKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------ESFGSSMGSHGAAG-----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------HAPAPGGGLGGFG-----------------------------
Mb2878|M.bovis_AF2122/97 --TAGFDGNPGQPG----------------
Rv2853|M.tuberculosis_H37Rv --TAGFDGNPGQPG----------------
MMAR_2490|M.marinum_M --HTGLDGAPGQPG----------------
MUL_0572|M.ulcerans_Agy99 SPVPGVGGKGGNPGPGGKPGPNGADGIVV-
Mflv_5091|M.gilvum_PYR-GCK AG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 AG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 SGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---TGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 ------------------------------
MAV_4827|M.avium_104 ----GGHSGGGLGGLGGGHK----------