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SFVITAPELISAAATDLAGIGSTISAANAAASASTTAVAAAAADEVSTAVATLFGAHAQQYQSLGSQMAA FHDDFVRILASGSNLYATAEATNASPLQPLLDLINAPTQAILGRPLIGNGSNGTYPGQDGRDGGLLIGNG GNGAAGDFGQAGGGGGSAGLFGDGGNGGTGGAGSAGGNGGTGGLLFGNGGNGGMGGTATLGFNGGMAGAG GNGGSALLFGSGGAGGQGGTGVAGTNGSNPLVFDTANPGAAGQDVTTTDDPAANPLTGGNGSEGAAGSTI QNGGVGGQGGSATSTNQNSALGGEGGKGGDGANGGMGGNGGSGDTSGQTDAPQPSATGGNGGNGGDAQVA GGAGGAGGWGGDGHANQGDAVGGVGGRGGAGFASSAAGGAGGTGGTGGQGGNGGLLFGNGGTGGVGGTGG MGGAGAAGGTGGDGGNAGFAIGGSDGTATGQQGGDGGYGADSTAVGGTGGAGGTGGNGGNGGWLIGSGGA GGVSGTGGVGGTGGAGGAGGIGGIGGNTSSSSTASVAGEGGHGGDGGDGGDGGNGGAAGAVAGAGGRGGL IGAAGGTGSIGAGGAAGAGGAGGAGGAGGAGGTAQGSGASGGTGANGHTGLDGAPGQPG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2490 | - | - | 100% (620) | PE-PGRS family protein, PE_PGRS15_1 |
M. marinum M | MMAR_2492 | - | 0.0 | 58.92% (650) | PE-PGRS family protein, PE_PGRS15_2 |
M. marinum M | MMAR_2481 | - | 0.0 | 54.48% (681) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | 0.0 | 59.46% (624) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-116 | 44.37% (595) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv2853 | PE_PGRS48 | 0.0 | 59.13% (624) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 3e-14 | 39.58% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 3e-44 | 29.58% (622) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 4e-21 | 37.37% (190) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-91 | 37.46% (702) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 3e-46 | 40.24% (328) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3318 | - | 1e-155 | 47.65% (680) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-114 | 47.50% (520) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb2878|M.bovis_AF2122/97 -------------------------------------------------- Rv2853|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------------- Rv2853|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------------- Rv2853|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------------- Rv2853|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb2878|M.bovis_AF2122/97 ------------------------------------MLYVVASPDLMTAA Rv2853|M.tuberculosis_H37Rv ------------------------------------MLYVVASPDLMTAA MMAR_2490|M.marinum_M ------------------------------------MSFVITAPELISAA MUL_3318|M.ulcerans_Agy99 ------------------------------------MSYLAIAPEIVAAA Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MLBr_01183|M.leprae_Br4923 -----------------------------------MPLFLNAEPQALTAA MAV_4827|M.avium_104 --------------------------------MNIVLGVSMAPSSIQMVV Mb2878|M.bovis_AF2122/97 ATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQIAALFGAHARSYQT Rv2853|M.tuberculosis_H37Rv ATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQIAALFGAHARSYQT MMAR_2490|M.marinum_M ATDLAGIGSTISAANAAASASTTAVAAAAADEVSTAVATLFGAHAQQYQS MUL_3318|M.ulcerans_Agy99 AADMDGIGSPITAANAAAAIPTSAIAAAAADEISAAIAELFGNHAQQYQA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN MLBr_01183|M.leprae_Br4923 ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA MAV_4827|M.avium_104 LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ Mb2878|M.bovis_AF2122/97 LSTQAAAFHSRFVQALTTAAASYASVEAANASPLQVALDVINAPAQTLLG Rv2853|M.tuberculosis_H37Rv LSTQAAAFHSRFVQALTTAAASYASVEAANASPLQVALDVINAPAQTLLG MMAR_2490|M.marinum_M LGSQMAAFHDDFVRILASGSNLYATAEATNASPLQPLLDLINAPTQAILG MUL_3318|M.ulcerans_Agy99 LSAQMARFHDQFVRSLSGAAQTYARAEATGAAPLQPVLDLINGPTQALLG Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_4284c|M.abscessus_ATCC_199 TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETANHDSL---------------- MAV_4827|M.avium_104 LSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG Mb2878|M.bovis_AF2122/97 RPLIG-------------NGADGST-PGQAGGPGG-------------LL Rv2853|M.tuberculosis_H37Rv RPLIG-------------NGADGST-PGQAGGPGG-------------LL MMAR_2490|M.marinum_M RPLIG-------------NGSNGTY-PGQDGRDGG-------------LL MUL_3318|M.ulcerans_Agy99 RPLIG-------------NGTSGALGTGQAGGDGG-------------LL Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 PIASG-------------NQVMSPSGNVDSFNRGP--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 YERTA----------VLLVEPDTATLAVVETSDGS--------------- Mb2878|M.bovis_AF2122/97 YGN------------------------GGNGAAGG--------------- Rv2853|M.tuberculosis_H37Rv YGN------------------------GGNGAAGG--------------- MMAR_2490|M.marinum_M IGN------------------------GGNGAAGD--------------- MUL_3318|M.ulcerans_Agy99 IGNGTSGALGTGQAGGDGGLLIGNGGAGGSGAAGQ--------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------ Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------ MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------LLDLSFGDLQFGN--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------IPDVYKQQIRAESYGDAAG--------------- Mb2878|M.bovis_AF2122/97 -PNQAGGAGGNAGLIGNGGAGGAGGVG-------------AVGGNGGTGG Rv2853|M.tuberculosis_H37Rv -PNQAGGAGGNAGLIGNGGAGGAGGVG-------------AVGGKRGTGG MMAR_2490|M.marinum_M -FGQAGGGGGSAGLFGDGGNGGTGGAG-------------SAGGNGGTGG MUL_3318|M.ulcerans_Agy99 -AGGAGGAGGAAGLIGSGGAGGIGGTG-------------AAGGKGGN-A Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF MAB_4284c|M.abscessus_ATCC_199 -RDTTAIGDGAVAVGGSNSGPIASGQG------------STAVNGDVRDS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --QLSAMVAGLEKLESLPGGLLLVGSG-----------VDVAPLKQVLQT Mb2878|M.bovis_AF2122/97 LLFGNGGAGGQG--------------------GLGLAGINGGSGG----- Rv2853|M.tuberculosis_H37Rv LLFGNGGAGGQG--------------------GLGLAGINGGSGG----- MMAR_2490|M.marinum_M LLFGNGGNGGMG--------------------GTATLGFNGGMAG----- MUL_3318|M.ulcerans_Agy99 VLFGAGGNGGIG--------------------GTGAVGGTGAVGG----- Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------GSGVDG------------ MAB_4284c|M.abscessus_ATCC_199 NIINADHGSNVG-------------------VDQSQTRVGGDYTN----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TTFLDVSVAEEP--------------------ETALARGAALAAAN---- Mb2878|M.bovis_AF2122/97 -----------QGGHGGNA------------------------------- Rv2853|M.tuberculosis_H37Rv -----------QGGHGGNA------------------------------- MMAR_2490|M.marinum_M -----------AGGNGGSA------------------------------- MUL_3318|M.ulcerans_Agy99 -----------AGGNGG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG----------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA TH_3810|M.thermoresistible__bu -----------VDVVGG--------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------VSGHGSADIDKS--------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------APLFASST------------------------------- Mb2878|M.bovis_AF2122/97 --ILFGQGGAGGPGGTG----------------------------AMGVA Rv2853|M.tuberculosis_H37Rv --ILFGQGGAGGPGGTG----------------------------AMGVA MMAR_2490|M.marinum_M --LLFGSGGAGGQGGTG----------------------------VAGTN MUL_3318|M.ulcerans_Agy99 --FLFGHGGDGGTGGTG----------------------------ASAAA Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES MAB_4284c|M.abscessus_ATCC_199 -VTVVDDHSQRNTTNIN--------------------------DSFNTDR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --AALAYAQDPGTGAVDQYSLP---------------------DYLYVPV Mb2878|M.bovis_AF2122/97 GTNPTPIGTAAP---------------------GSDG------------- Rv2853|M.tuberculosis_H37Rv GTNPTPIGTAAP---------------------GSDG------------- MMAR_2490|M.marinum_M GSNPLVFDTANP---------------------GAAGQD----------- MUL_3318|M.ulcerans_Agy99 GANGGAGQTGLA---------------------GTDGGT----------- Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD----------- Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN----------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP TH_3810|M.thermoresistible__bu HTPGVYTDRQ---------------------------------------- MAB_4284c|M.abscessus_ATCC_199 STNIGSGNTTNTEIG----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 DPEPGDDELAYSAVG----------------------------------- Mb2878|M.bovis_AF2122/97 -----------VNQIGNGGN---TDLTGGAGGDGN--------------- Rv2853|M.tuberculosis_H37Rv -----------VNQIGNGGN---TDLTGGAGGDGN--------------- MMAR_2490|M.marinum_M -----------VTTTDDPAA---NPLTGGNGSEGA--------------- MUL_3318|M.ulcerans_Agy99 -----------GGASGEGGAGGKGGLLFGAGGEGG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 -----------SHNQANIGTSTSAGGSAAVGGNAG--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------EEDAESPTVVIEKLFLPEDSEPR--------------- Mb2878|M.bovis_AF2122/97 --AGSTTVNGGNGGTGGA----ARNSSGGTGNSFGGAGGAGGDGANGGDG Rv2853|M.tuberculosis_H37Rv --AGSTTVNGGNGGTGGA----ARNSSGGTGNSFGGAGGAGGDGANGGDG MMAR_2490|M.marinum_M --AGSTIQNGGVGGQGGS----ATSTNQNS--ALGGEGGKGGDGANGGMG MUL_3318|M.ulcerans_Agy99 --AGGTGGAGGTGGAGGDG--LAATTAGGTG-GNAGDGGEGGAGGNAGAG Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --RRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIV Mb2878|M.bovis_AF2122/97 GAGGEALTEGG-----ATAVSGAGGKGGNAEASG--------GAGGNGGK Rv2853|M.tuberculosis_H37Rv GAGGEALTEGG-----ATAVSGAGGKGGNAEASG--------GAGGNGGK MMAR_2490|M.marinum_M GNGGSGDTSGQTDAPQPSATGGNGGNGGDAQVAG--------GAGGAGGW MUL_3318|M.ulcerans_Agy99 GAGGQGGLFGNAG---TTGAGGDGGNGGNGGLAGN------GGAGGNGDA Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG------GDGGTGGTGGTGGTG---------GTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG------GTGGTGGTGGTGGTG---------GTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGV--GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN TH_3810|M.thermoresistible__bu GRGGFLGIGGSG---------GWGGHGGNGGD-----------TDADGGN MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAG----LAGNAGLAGNAGLAGNAG------LAGNAGLAGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSP--------PVAAPLPA Mb2878|M.bovis_AF2122/97 ----GGFAQATTS-------VTGGNGGNGGNGHDSNAPGGAGGS------ Rv2853|M.tuberculosis_H37Rv ----GGFAQATTS-------VTGGNGGNGGNGHDSNAPGGAGGS------ MMAR_2490|M.marinum_M ----GGDGHANQGD------AVGGVGGRGGAGFASSAAGGAGGT------ MUL_3318|M.ulcerans_Agy99 SNPNGGTGGNAANP------GAGGAGGAGGNGSRTGAPGTTGNTP----- Mflv_5091|M.gilvum_PYR-GCK ----GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---- Mvan_1264|M.vanbaalenii_PYR-1 ----GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---- MSMEG_0868|M.smegmatis_MC2_155 ----GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI TH_3810|M.thermoresistible__bu ----GGDG---------------GNGGSAG-------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAG-------LAGNAGLAGNAGLAGNAGLAGNAAVAG-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 APPPAAPPLPEAPP------IPAAPPVVPVPVVVPPVPVPVPVRIP---- Mb2878|M.bovis_AF2122/97 -----------GGVGGDGGRGGLLAGNGGTG------------------- Rv2853|M.tuberculosis_H37Rv -----------GGVGGDGGRGGLLAGNGGTG------------------- MMAR_2490|M.marinum_M -----------GGTGGQGGNGGLLFGNGGTG------------------- MUL_3318|M.ulcerans_Agy99 -----------TTAAGHGGKGGDGFNPATSG------------------- Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG------------------- MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG TH_3810|M.thermoresistible__bu -------------RGGTGGLRGVFGINGGNG------------------- MAB_4284c|M.abscessus_ATCC_199 -------------NAAVAGNAAVAGNAAVGG------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------VPDPVSPPQLLAPPRLSVP------------------ Mb2878|M.bovis_AF2122/97 ----GAGGNGGTGGAGAPGGAGGAGGKADIANSLGDNATVTGGNGGTGGD Rv2853|M.tuberculosis_H37Rv ----GAGGNGGTGGAGAPGGAGGAGGKADIANSLGDNATVTGGNGGTGGD MMAR_2490|M.marinum_M ----GVGGTGGMGGAGAAGGTGGDGGNAGFAIG-GSDGTATGQQGGDGGY MUL_3318|M.ulcerans_Agy99 ----QDGGSGGKGGDAGQFGNGGNGGNG--AAGDAAGSGHTGGNGGAGGG Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL TH_3810|M.thermoresistible__bu -----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGG MAB_4284c|M.abscessus_ATCC_199 --VLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---QPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNY Mb2878|M.bovis_AF2122/97 GGSALGTG--GAGGAGGLGGHGGAGGLLIGNGG--AGGAGGLGGAGG--- Rv2853|M.tuberculosis_H37Rv GGSALGTG--GAGGAGGLGGHGGAGGLLIGNGG--AGGAGGLGGAGG--- MMAR_2490|M.marinum_M GADSTAVG--GTGGAGGTGGNGGNGGWLIGSGG--AGGVSGTGGVGG--- MUL_3318|M.ulcerans_Agy99 GGNAGQFGEPGTGGSGGNGGKGGDG-AAGGNGG--TGGIGGTGGIGGDGR Mflv_5091|M.gilvum_PYR-GCK GGFGGSGG---TGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG--- Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGG---TGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG--- MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGV---VNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSW TH_3810|M.thermoresistible__bu GGTPSAGF---GVPTTIQFPAGSCTSRAVSREG----------------- MAB_4284c|M.abscessus_ATCC_199 STGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGG--------HVPTPGAGGSGGSGGGHVPTPG--AGGSGGSGGGHVP-- Mb2878|M.bovis_AF2122/97 ---------AGGAGGEGGAGGAGGEAIPGGASTNS-------------AG Rv2853|M.tuberculosis_H37Rv ---------AGGAGGEGGAGGAGGEAIPGGASTNS-------------AG MMAR_2490|M.marinum_M ---------TGGAGGAGGIGGIGGNTSS--SSTAS-------------VA MUL_3318|M.ulcerans_Agy99 NGSTGAIGGNGGTGGTGGTGGTGGKSLGNLPSGDGG------------VG Mflv_5091|M.gilvum_PYR-GCK --GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-AT Mvan_1264|M.vanbaalenii_PYR-1 --GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-AT MSMEG_0868|M.smegmatis_MC2_155 V-QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVAT TH_3810|M.thermoresistible__bu --------IMPSSRAASARAG---------------------------AA MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVN-------------TG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------TPGTGGPGGTGGSGGGHVPTPGAGTP-------------GG Mb2878|M.bovis_AF2122/97 GDGGAGGTGGNGGDGGAGGAPG--------------LGGAGGAGGWLIGQ Rv2853|M.tuberculosis_H37Rv GDGGAGGTGGNGGDGGAGGAPG--------------LGGAGGAGGWLIGQ MMAR_2490|M.marinum_M GEGGHGGDGGDGGDGGNGGAAG--------------AVAGAGGRGGLIGA MUL_3318|M.ulcerans_Agy99 GNAGTGGNGGNATDGGAGGKGG--------------DGAAGGTGG-NAGE Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGA Mvan_1264|M.vanbaalenii_PYR-1 GASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGA MSMEG_0868|M.smegmatis_MC2_155 GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGG TH_3810|M.thermoresistible__bu CASSTSRSRRSFCCSRA--------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVG--------------GSTAVGGGAHTSAI MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SGGGHLPFPGAGSTPGGSGGGH-------------LPTPGAGTPGGGLGG Mb2878|M.bovis_AF2122/97 SGSTGGGG------------------------------------AGGAGG Rv2853|M.tuberculosis_H37Rv SGSTGGGG------------------------------------AGGAGG MMAR_2490|M.marinum_M AGGTGSIG------------------------------------AGGAAG MUL_3318|M.ulcerans_Agy99 FQSLLGIS------------------------------------KGGDGG Mflv_5091|M.gilvum_PYR-GCK NGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGG Mvan_1264|M.vanbaalenii_PYR-1 NGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGG MSMEG_0868|M.smegmatis_MC2_155 NGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NDALGGSG-----------------------------------SVGGSTA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 FG-------------------------------------------GGHAP Mb2878|M.bovis_AF2122/97 AGG-------------------------------------AGGAGGSGGA Rv2853|M.tuberculosis_H37Rv AGG-------------------------------------AGGAGGSGGA MMAR_2490|M.marinum_M AGG-------------------------------------AGGAGGAGGA MUL_3318|M.ulcerans_Agy99 TGG-------------------------------------DGGTGTPVGA Mflv_5091|M.gilvum_PYR-GCK AGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGA Mvan_1264|M.vanbaalenii_PYR-1 AGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGA MSMEG_0868|M.smegmatis_MC2_155 NGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGG---------------------GAHTSAINESMNSSINASHSSSMNES MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 APG--------------------------------------GGLGGGGGH Mb2878|M.bovis_AF2122/97 GG--HGDTTSGKNGSS--GTAGFDGNPGQPG-------- Rv2853|M.tuberculosis_H37Rv GG--HGDTTSGKNGSS--GTAGFDGNPGQPG-------- MMAR_2490|M.marinum_M GGTAQGSGASGGTGAN--GHTGLDGAPGQPG-------- MUL_3318|M.ulcerans_Agy99 DG-LAGTGGAGGFGIFPGGQTGQNGTDSKAG-------- Mflv_5091|M.gilvum_PYR-GCK GGSGAGGAG--GAGGS-GGSGGSGGSGGSGGAAGDSDD- Mvan_1264|M.vanbaalenii_PYR-1 GGSGTGGAG--GAGGS-GGSGGSGGAGGSGGAAGDSD-- MSMEG_0868|M.smegmatis_MC2_155 GGTTAGGSGNGGNGGN-GGNGGADGTPGTAGTTGANNP- TH_3810|M.thermoresistible__bu --------------------------------------- MAB_4284c|M.abscessus_ATCC_199 FGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH MLBr_01183|M.leprae_Br4923 --------------------------------------- MAV_4827|M.avium_104 APAPGGGLGGFGGGHSGGGLGGLGGGHK-----------