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M. marinum M MMAR_2490 (-)

annotation: PE-PGRS family protein, PE_PGRS15_1
coordinates: 3029692 - 3031554
length: 620

SFVITAPELISAAATDLAGIGSTISAANAAASASTTAVAAAAADEVSTAVATLFGAHAQQYQSLGSQMAA
FHDDFVRILASGSNLYATAEATNASPLQPLLDLINAPTQAILGRPLIGNGSNGTYPGQDGRDGGLLIGNG
GNGAAGDFGQAGGGGGSAGLFGDGGNGGTGGAGSAGGNGGTGGLLFGNGGNGGMGGTATLGFNGGMAGAG
GNGGSALLFGSGGAGGQGGTGVAGTNGSNPLVFDTANPGAAGQDVTTTDDPAANPLTGGNGSEGAAGSTI
QNGGVGGQGGSATSTNQNSALGGEGGKGGDGANGGMGGNGGSGDTSGQTDAPQPSATGGNGGNGGDAQVA
GGAGGAGGWGGDGHANQGDAVGGVGGRGGAGFASSAAGGAGGTGGTGGQGGNGGLLFGNGGTGGVGGTGG
MGGAGAAGGTGGDGGNAGFAIGGSDGTATGQQGGDGGYGADSTAVGGTGGAGGTGGNGGNGGWLIGSGGA
GGVSGTGGVGGTGGAGGAGGIGGIGGNTSSSSTASVAGEGGHGGDGGDGGDGGNGGAAGAVAGAGGRGGL
IGAAGGTGSIGAGGAAGAGGAGGAGGAGGAGGTAQGSGASGGTGANGHTGLDGAPGQPG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2490--100% (620)PE-PGRS family protein, PE_PGRS15_1
M. marinum MMMAR_2492-0.058.92% (650) PE-PGRS family protein, PE_PGRS15_2
M. marinum MMMAR_2481-0.054.48% (681) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2878PE_PGRS480.059.46% (624) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-11644.37% (595) triple helix repeat-containing collagen
M. tuberculosis H37RvRv2853PE_PGRS480.059.13% (624) PE-PGRS family protein
M. leprae Br4923MLBr_01183-3e-1439.58% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-3e-4429.58% (622) hypothetical protein MAB_4284c
M. avium 104MAV_4827-4e-2137.37% (190) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-2e-9137.46% (702) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-3e-4640.24% (328) PUTATIVE -
M. ulcerans Agy99MUL_3318-1e-15547.65% (680) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-11447.50% (520) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb2878|M.bovis_AF2122/97            --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2490|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2490|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2490|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2490|M.marinum_M               --------------------------------------------------
MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            ------------------------------------MLYVVASPDLMTAA
Rv2853|M.tuberculosis_H37Rv         ------------------------------------MLYVVASPDLMTAA
MMAR_2490|M.marinum_M               ------------------------------------MSFVITAPELISAA
MUL_3318|M.ulcerans_Agy99           ------------------------------------MSYLAIAPEIVAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          -----------------------------------MPLFLNAEPQALTAA
MAV_4827|M.avium_104                --------------------------------MNIVLGVSMAPSSIQMVV
                                                                                      

Mb2878|M.bovis_AF2122/97            ATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQIAALFGAHARSYQT
Rv2853|M.tuberculosis_H37Rv         ATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQIAALFGAHARSYQT
MMAR_2490|M.marinum_M               ATDLAGIGSTISAANAAASASTTAVAAAAADEVSTAVATLFGAHAQQYQS
MUL_3318|M.ulcerans_Agy99           AADMDGIGSPITAANAAAAIPTSAIAAAAADEISAAIAELFGNHAQQYQA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199      VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MLBr_01183|M.leprae_Br4923          ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MAV_4827|M.avium_104                LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ
                                                                                      

Mb2878|M.bovis_AF2122/97            LSTQAAAFHSRFVQALTTAAASYASVEAANASPLQVALDVINAPAQTLLG
Rv2853|M.tuberculosis_H37Rv         LSTQAAAFHSRFVQALTTAAASYASVEAANASPLQVALDVINAPAQTLLG
MMAR_2490|M.marinum_M               LGSQMAAFHDDFVRILASGSNLYATAEATNASPLQPLLDLINAPTQAILG
MUL_3318|M.ulcerans_Agy99           LSAQMARFHDQFVRSLSGAAQTYARAEATGAAPLQPVLDLINGPTQALLG
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199      TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN
MLBr_01183|M.leprae_Br4923          HASQGATNHQDLIQSLLTSSSAYAGTETANHDSL----------------
MAV_4827|M.avium_104                LSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG
                                                                                      

Mb2878|M.bovis_AF2122/97            RPLIG-------------NGADGST-PGQAGGPGG-------------LL
Rv2853|M.tuberculosis_H37Rv         RPLIG-------------NGADGST-PGQAGGPGG-------------LL
MMAR_2490|M.marinum_M               RPLIG-------------NGSNGTY-PGQDGRDGG-------------LL
MUL_3318|M.ulcerans_Agy99           RPLIG-------------NGTSGALGTGQAGGDGG-------------LL
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      PIASG-------------NQVMSPSGNVDSFNRGP---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                YERTA----------VLLVEPDTATLAVVETSDGS---------------
                                                                                      

Mb2878|M.bovis_AF2122/97            YGN------------------------GGNGAAGG---------------
Rv2853|M.tuberculosis_H37Rv         YGN------------------------GGNGAAGG---------------
MMAR_2490|M.marinum_M               IGN------------------------GGNGAAGD---------------
MUL_3318|M.ulcerans_Agy99           IGNGTSGALGTGQAGGDGGLLIGNGGAGGSGAAGQ---------------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------LLDLSFGDLQFGN---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------IPDVYKQQIRAESYGDAAG---------------
                                                                                      

Mb2878|M.bovis_AF2122/97            -PNQAGGAGGNAGLIGNGGAGGAGGVG-------------AVGGNGGTGG
Rv2853|M.tuberculosis_H37Rv         -PNQAGGAGGNAGLIGNGGAGGAGGVG-------------AVGGKRGTGG
MMAR_2490|M.marinum_M               -FGQAGGGGGSAGLFGDGGNGGTGGAG-------------SAGGNGGTGG
MUL_3318|M.ulcerans_Agy99           -AGGAGGAGGAAGLIGSGGAGGIGGTG-------------AAGGKGGN-A
Mflv_5091|M.gilvum_PYR-GCK          -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1       -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MAB_4284c|M.abscessus_ATCC_199      -RDTTAIGDGAVAVGGSNSGPIASGQG------------STAVNGDVRDS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --QLSAMVAGLEKLESLPGGLLLVGSG-----------VDVAPLKQVLQT
                                                                                      

Mb2878|M.bovis_AF2122/97            LLFGNGGAGGQG--------------------GLGLAGINGGSGG-----
Rv2853|M.tuberculosis_H37Rv         LLFGNGGAGGQG--------------------GLGLAGINGGSGG-----
MMAR_2490|M.marinum_M               LLFGNGGNGGMG--------------------GTATLGFNGGMAG-----
MUL_3318|M.ulcerans_Agy99           VLFGAGGNGGIG--------------------GTGAVGGTGAVGG-----
Mflv_5091|M.gilvum_PYR-GCK          ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1       ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      SLFNLGGAGGWG--------------------GSGVDG------------
MAB_4284c|M.abscessus_ATCC_199      NIINADHGSNVG-------------------VDQSQTRVGGDYTN-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TTFLDVSVAEEP--------------------ETALARGAALAAAN----
                                                                                      

Mb2878|M.bovis_AF2122/97            -----------QGGHGGNA-------------------------------
Rv2853|M.tuberculosis_H37Rv         -----------QGGHGGNA-------------------------------
MMAR_2490|M.marinum_M               -----------AGGNGGSA-------------------------------
MUL_3318|M.ulcerans_Agy99           -----------AGGNGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      -----------VDVVGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------VSGHGSADIDKS---------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------APLFASST-------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            --ILFGQGGAGGPGGTG----------------------------AMGVA
Rv2853|M.tuberculosis_H37Rv         --ILFGQGGAGGPGGTG----------------------------AMGVA
MMAR_2490|M.marinum_M               --LLFGSGGAGGQGGTG----------------------------VAGTN
MUL_3318|M.ulcerans_Agy99           --FLFGHGGDGGTGGTG----------------------------ASAAA
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      -------NPDGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199      -VTVVDDHSQRNTTNIN--------------------------DSFNTDR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --AALAYAQDPGTGAVDQYSLP---------------------DYLYVPV
                                                                                      

Mb2878|M.bovis_AF2122/97            GTNPTPIGTAAP---------------------GSDG-------------
Rv2853|M.tuberculosis_H37Rv         GTNPTPIGTAAP---------------------GSDG-------------
MMAR_2490|M.marinum_M               GSNPLVFDTANP---------------------GAAGQD-----------
MUL_3318|M.ulcerans_Agy99           GANGGAGQTGLA---------------------GTDGGT-----------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STNIGSGNTTNTEIG-----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DPEPGDDELAYSAVG-----------------------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            -----------VNQIGNGGN---TDLTGGAGGDGN---------------
Rv2853|M.tuberculosis_H37Rv         -----------VNQIGNGGN---TDLTGGAGGDGN---------------
MMAR_2490|M.marinum_M               -----------VTTTDDPAA---NPLTGGNGSEGA---------------
MUL_3318|M.ulcerans_Agy99           -----------GGASGEGGAGGKGGLLFGAGGEGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      -----------SHNQANIGTSTSAGGSAAVGGNAG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------EEDAESPTVVIEKLFLPEDSEPR---------------
                                                                                      

Mb2878|M.bovis_AF2122/97            --AGSTTVNGGNGGTGGA----ARNSSGGTGNSFGGAGGAGGDGANGGDG
Rv2853|M.tuberculosis_H37Rv         --AGSTTVNGGNGGTGGA----ARNSSGGTGNSFGGAGGAGGDGANGGDG
MMAR_2490|M.marinum_M               --AGSTIQNGGVGGQGGS----ATSTNQNS--ALGGEGGKGGDGANGGMG
MUL_3318|M.ulcerans_Agy99           --AGGTGGAGGTGGAGGDG--LAATTAGGTG-GNAGDGGEGGAGGNAGAG
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu      -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_4284c|M.abscessus_ATCC_199      --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --RRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIV
                                                                                      

Mb2878|M.bovis_AF2122/97            GAGGEALTEGG-----ATAVSGAGGKGGNAEASG--------GAGGNGGK
Rv2853|M.tuberculosis_H37Rv         GAGGEALTEGG-----ATAVSGAGGKGGNAEASG--------GAGGNGGK
MMAR_2490|M.marinum_M               GNGGSGDTSGQTDAPQPSATGGNGGNGGDAQVAG--------GAGGAGGW
MUL_3318|M.ulcerans_Agy99           GAGGQGGLFGNAG---TTGAGGDGGNGGNGGLAGN------GGAGGNGDA
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGAGGTG------GDGGTGGTGGTGGTG---------GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGDGGTG------GTGGTGGTGGTGGTG---------GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GDGALGGNGGTGGV--GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN
TH_3810|M.thermoresistible__bu      GRGGFLGIGGSG---------GWGGHGGNGGD-----------TDADGGN
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAG----LAGNAGLAGNAGLAGNAG------LAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSP--------PVAAPLPA
                                                                                      

Mb2878|M.bovis_AF2122/97            ----GGFAQATTS-------VTGGNGGNGGNGHDSNAPGGAGGS------
Rv2853|M.tuberculosis_H37Rv         ----GGFAQATTS-------VTGGNGGNGGNGHDSNAPGGAGGS------
MMAR_2490|M.marinum_M               ----GGDGHANQGD------AVGGVGGRGGAGFASSAAGGAGGT------
MUL_3318|M.ulcerans_Agy99           SNPNGGTGGNAANP------GAGGAGGAGGNGSRTGAPGTTGNTP-----
Mflv_5091|M.gilvum_PYR-GCK          ----GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1       ----GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155      ----GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu      ----GGDG---------------GNGGSAG--------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAG-------LAGNAGLAGNAGLAGNAGLAGNAAVAG--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                APPPAAPPLPEAPP------IPAAPPVVPVPVVVPPVPVPVPVRIP----
                                                                                      

Mb2878|M.bovis_AF2122/97            -----------GGVGGDGGRGGLLAGNGGTG-------------------
Rv2853|M.tuberculosis_H37Rv         -----------GGVGGDGGRGGLLAGNGGTG-------------------
MMAR_2490|M.marinum_M               -----------GGTGGQGGNGGLLFGNGGTG-------------------
MUL_3318|M.ulcerans_Agy99           -----------TTAAGHGGKGGDGFNPATSG-------------------
Mflv_5091|M.gilvum_PYR-GCK          -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155      RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu      -------------RGGTGGLRGVFGINGGNG-------------------
MAB_4284c|M.abscessus_ATCC_199      -------------NAAVAGNAAVAGNAAVGG-------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------VPDPVSPPQLLAPPRLSVP------------------
                                                                                      

Mb2878|M.bovis_AF2122/97            ----GAGGNGGTGGAGAPGGAGGAGGKADIANSLGDNATVTGGNGGTGGD
Rv2853|M.tuberculosis_H37Rv         ----GAGGNGGTGGAGAPGGAGGAGGKADIANSLGDNATVTGGNGGTGGD
MMAR_2490|M.marinum_M               ----GVGGTGGMGGAGAAGGTGGDGGNAGFAIG-GSDGTATGQQGGDGGY
MUL_3318|M.ulcerans_Agy99           ----QDGGSGGKGGDAGQFGNGGNGGNG--AAGDAAGSGHTGGNGGAGGG
Mflv_5091|M.gilvum_PYR-GCK          ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155      TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu      -----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGG
MAB_4284c|M.abscessus_ATCC_199      --VLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---QPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNY
                                                                                      

Mb2878|M.bovis_AF2122/97            GGSALGTG--GAGGAGGLGGHGGAGGLLIGNGG--AGGAGGLGGAGG---
Rv2853|M.tuberculosis_H37Rv         GGSALGTG--GAGGAGGLGGHGGAGGLLIGNGG--AGGAGGLGGAGG---
MMAR_2490|M.marinum_M               GADSTAVG--GTGGAGGTGGNGGNGGWLIGSGG--AGGVSGTGGVGG---
MUL_3318|M.ulcerans_Agy99           GGNAGQFGEPGTGGSGGNGGKGGDG-AAGGNGG--TGGIGGTGGIGGDGR
Mflv_5091|M.gilvum_PYR-GCK          GGFGGSGG---TGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG---
Mvan_1264|M.vanbaalenii_PYR-1       GGFGGVGG---TGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG---
MSMEG_0868|M.smegmatis_MC2_155      GGNGGDGV---VNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSW
TH_3810|M.thermoresistible__bu      GGTPSAGF---GVPTTIQFPAGSCTSRAVSREG-----------------
MAB_4284c|M.abscessus_ATCC_199      STGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGG--------HVPTPGAGGSGGSGGGHVPTPG--AGGSGGSGGGHVP--
                                                                                      

Mb2878|M.bovis_AF2122/97            ---------AGGAGGEGGAGGAGGEAIPGGASTNS-------------AG
Rv2853|M.tuberculosis_H37Rv         ---------AGGAGGEGGAGGAGGEAIPGGASTNS-------------AG
MMAR_2490|M.marinum_M               ---------TGGAGGAGGIGGIGGNTSS--SSTAS-------------VA
MUL_3318|M.ulcerans_Agy99           NGSTGAIGGNGGTGGTGGTGGTGGKSLGNLPSGDGG------------VG
Mflv_5091|M.gilvum_PYR-GCK          --GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-AT
Mvan_1264|M.vanbaalenii_PYR-1       --GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-AT
MSMEG_0868|M.smegmatis_MC2_155      V-QSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVAT
TH_3810|M.thermoresistible__bu      --------IMPSSRAASARAG---------------------------AA
MAB_4284c|M.abscessus_ATCC_199      HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVN-------------TG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------TPGTGGPGGTGGSGGGHVPTPGAGTP-------------GG
                                                                                      

Mb2878|M.bovis_AF2122/97            GDGGAGGTGGNGGDGGAGGAPG--------------LGGAGGAGGWLIGQ
Rv2853|M.tuberculosis_H37Rv         GDGGAGGTGGNGGDGGAGGAPG--------------LGGAGGAGGWLIGQ
MMAR_2490|M.marinum_M               GEGGHGGDGGDGGDGGNGGAAG--------------AVAGAGGRGGLIGA
MUL_3318|M.ulcerans_Agy99           GNAGTGGNGGNATDGGAGGKGG--------------DGAAGGTGG-NAGE
Mflv_5091|M.gilvum_PYR-GCK          GAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGA
Mvan_1264|M.vanbaalenii_PYR-1       GASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGA
MSMEG_0868|M.smegmatis_MC2_155      GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGG
TH_3810|M.thermoresistible__bu      CASSTSRSRRSFCCSRA---------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGVGSHVGGGISESLGGSGSVG--------------GSTAVGGGAHTSAI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SGGGHLPFPGAGSTPGGSGGGH-------------LPTPGAGTPGGGLGG
                                                                                      

Mb2878|M.bovis_AF2122/97            SGSTGGGG------------------------------------AGGAGG
Rv2853|M.tuberculosis_H37Rv         SGSTGGGG------------------------------------AGGAGG
MMAR_2490|M.marinum_M               AGGTGSIG------------------------------------AGGAAG
MUL_3318|M.ulcerans_Agy99           FQSLLGIS------------------------------------KGGDGG
Mflv_5091|M.gilvum_PYR-GCK          NGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGG
Mvan_1264|M.vanbaalenii_PYR-1       NGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGG
MSMEG_0868|M.smegmatis_MC2_155      NGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NDALGGSG-----------------------------------SVGGSTA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                FG-------------------------------------------GGHAP
                                                                                      

Mb2878|M.bovis_AF2122/97            AGG-------------------------------------AGGAGGSGGA
Rv2853|M.tuberculosis_H37Rv         AGG-------------------------------------AGGAGGSGGA
MMAR_2490|M.marinum_M               AGG-------------------------------------AGGAGGAGGA
MUL_3318|M.ulcerans_Agy99           TGG-------------------------------------DGGTGTPVGA
Mflv_5091|M.gilvum_PYR-GCK          AGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGA
Mvan_1264|M.vanbaalenii_PYR-1       AGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGA
MSMEG_0868|M.smegmatis_MC2_155      NGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGG---------------------GAHTSAINESMNSSINASHSSSMNES
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                APG--------------------------------------GGLGGGGGH
                                                                                      

Mb2878|M.bovis_AF2122/97            GG--HGDTTSGKNGSS--GTAGFDGNPGQPG--------
Rv2853|M.tuberculosis_H37Rv         GG--HGDTTSGKNGSS--GTAGFDGNPGQPG--------
MMAR_2490|M.marinum_M               GGTAQGSGASGGTGAN--GHTGLDGAPGQPG--------
MUL_3318|M.ulcerans_Agy99           DG-LAGTGGAGGFGIFPGGQTGQNGTDSKAG--------
Mflv_5091|M.gilvum_PYR-GCK          GGSGAGGAG--GAGGS-GGSGGSGGSGGSGGAAGDSDD-
Mvan_1264|M.vanbaalenii_PYR-1       GGSGTGGAG--GAGGS-GGSGGSGGAGGSGGAAGDSD--
MSMEG_0868|M.smegmatis_MC2_155      GGTTAGGSGNGGNGGN-GGNGGADGTPGTAGTTGANNP-
TH_3810|M.thermoresistible__bu      ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      FGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923          ---------------------------------------
MAV_4827|M.avium_104                APAPGGGLGGFGGGHSGGGLGGLGGGHK-----------