For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PGASGRKPASSTESSDAGFADSMAAYDALPRRVVHALDLVNFSLADVRDGLGPYLSVYLLVTNNWDQASI GFVMAVGGIAAIVAQTPMGAFVDRTKAKRALVITGALAVTASALAMPLFPELRSISLLQVLTGIASSVFA PALAAITLGIVGPQLFARRIGRNESFNHAGNATAAAITGGLAFFFGPVVVFWVLATMAAMSVVATLRIPH DAIDHDLARGMDHAPGEPHAQPSGFGVLLHNRTLMIFAAAVVAFHFANAAMLPLVGQVLALHNRDEGTAL MSWCIVAAQVVMVPVAYVTGSRADAWGRKPIFLVAFAVLTARGFLYTLSDNSYWLVGVQLLDGIGAGIFG ALFPLIVQDLTHGTGHFNISLGAITTAVGVGAALSNFASGWVVVTAGYNVAFMSLGAIAGAGFILYLLAM PETASARLAGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3804 | - | - | 100% (432) | integral membrane transport protein |
| M. marinum M | MMAR_3100 | ermB_1 | 3e-07 | 27.33% (150) | integral membrane drug efflux protein, ErmB_1 |
| M. marinum M | MMAR_1146 | - | 6e-06 | 26.58% (158) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2483c | - | 0.0 | 82.46% (399) | putative integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1475 | - | 7e-08 | 24.70% (166) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2456c | - | 0.0 | 82.46% (399) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3449c | - | 7e-13 | 25.36% (347) | putative transporter |
| M. avium 104 | MAV_1023 | - | 2e-67 | 37.82% (386) | MFS transporter |
| M. smegmatis MC2 155 | MSMEG_1455 | - | 3e-07 | 24.35% (382) | putative multidrug resistance protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3727 | - | 0.0 | 99.31% (432) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5855 | - | 6e-09 | 24.88% (410) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3804|M.marinum_M MPGASGRKPASSTESSDAGFADSMAAYDALPRRVVHALDLVNFSLADVRD
MUL_3727|M.ulcerans_Agy99 MPGASGRKPASSTESSDAGFADSMAAYDALPRRVVHALDLVNFSLADVRD
Mb2483c|M.bovis_AF2122/97 ---MSG-------------------TVVAVPPRVARALDLLNFSLADVRD
Rv2456c|M.tuberculosis_H37Rv ---MSG-------------------TVVAVPPRVARALDLLNFSLADVRD
MAV_1023|M.avium_104 -----------------------MTATPRACNRDRVALQAVHFFMADMEA
Mflv_1475|M.gilvum_PYR-GCK -------------------------MAPLSPTAQRAPLLAAGFTTAFGAH
MSMEG_1455|M.smegmatis_MC2_155 --------------MTDVRQTPTPDAAPPTGADTGTPLGLAALLAGTLVG
MAB_3449c|M.abscessus_ATCC_199 ------------------MSSCREGNADNATVKPRLPWEIWVLVVASLVI
Mvan_5855|M.vanbaalenii_PYR-1 --------------------------MNLVSGFRSFGWPSRMLMINQFGI
:
MMAR_3804|M.marinum_M GLG-PYLSVYLLVTNNWDQASIG--FVMAVGG-IAAIVAQTPMGAFVDRT
MUL_3727|M.ulcerans_Agy99 GLG-PYLSVYLLVTNNWDQASIG--FVMAVGG-IAAIVAQTPMGAFVDRT
Mb2483c|M.bovis_AF2122/97 GLG-PYLSIYLLLIHDWDQASIG--FVMAVGG-IAAIVAQTPIGALVDRT
Rv2456c|M.tuberculosis_H37Rv GLG-PYLSIYLLLIHDWDQASIG--FVMAVGG-IAAIVAQTPIGALVDRT
MAV_1023|M.avium_104 GMG-PFLGVLLQSR-GWTTGAIG--AAMTLGA-IVGMVTVAPAGALVDAT
Mflv_1475|M.gilvum_PYR-GCK AVA-GTLGTTTTGT-AASLLTLG--AMLAIYD-GAEVILKPLFGTLADRI
MSMEG_1455|M.smegmatis_MC2_155 TVSNNVVNVPLDAIIGEFDASLGNGVFVVVGF-LVCFAATIPLAGWFGDR
MAB_3449c|M.abscessus_ATCC_199 ALGFGVVAPALPQYARSFGVSVTAATAVVSSF-AAFRLVFAPVAGALVQR
Mvan_5855|M.vanbaalenii_PYR-1 NLGFYMLMPYLAGYLAGPLGLAAWAIGLVLGVRNFSQQGMFIIGGTLADR
:. : :. .
MMAR_3804|M.marinum_M KAKRALVITGALAVTASALAMPLFPELRSISLLQVLTGIASSVFAPALAA
MUL_3727|M.ulcerans_Agy99 KAKRALVITGALAITASALAMPLFPELRSISLLQVLTGIASSVFAPALAA
Mb2483c|M.bovis_AF2122/97 TAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAA
Rv2456c|M.tuberculosis_H37Rv TAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAA
MAV_1023|M.avium_104 RHKRGCVIVVGLAAVAASAVILTSRQFWTVATAQAVMCISGATIAPAMIG
Mflv_1475|M.gilvum_PYR-GCK GAR-TVLIAGLAVFAVASLSFAVADETAWLWAARLGQGIGAAAFSPAASA
MSMEG_1455|M.smegmatis_MC2_155 FGRRRVYCAALLATAVCAVGAATAPSLPLLIAWRSVGGVAAAAFAPAVMG
MAB_3449c|M.abscessus_ATCC_199 LGERWVYMSGLLIVAASTGICAFVHSYWQLLVFRSVGGVGSTMFTVSAAA
Mvan_5855|M.vanbaalenii_PYR-1 LGYKPLIVAGCVLRTVGFGLLVLADSLPAVLIASAATGFAGALFNPAVRA
.. : ...: : : .
MMAR_3804|M.marinum_M ITLGIVGPQLFARRIGRNESFNHAGNATAAAITGGLAFFFGPVVVFWVLA
MUL_3727|M.ulcerans_Agy99 ITLGIVGPQLFARRIGRNESFNHAGNATAAAITGGLAFFFGPVVVFWVLA
Mb2483c|M.bovis_AF2122/97 ITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLA
Rv2456c|M.tuberculosis_H37Rv ITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLA
MAV_1023|M.avium_104 ITLGVVGQAAFTRQNGRNQAYNHAGNMAGAALGGVAGWVFGYAGIFWLAA
Mflv_1475|M.gilvum_PYR-GCK LVARLAPASGQGRAFGTYGSYKSVGYTLGPLIGGAIVTFGGLQALFAVMA
MSMEG_1455|M.smegmatis_MC2_155 LLAWMFSGARRGRAMGAWASVNGIGQAVGPSLGGLVADHWGWRWIFVPLV
MAB_3449c|M.abscessus_ATCC_199 LLVRIAPEEIRGRAQGLYGSSFLLGMVAGPALGSAVVGLS-LSAPFIIYA
Mvan_5855|M.vanbaalenii_PYR-1 YLAVDAGPR-RLEAFALFNVFYQGGILAGPLVG-LALMFVDFRATAAAAA
. . * .. .
MMAR_3804|M.marinum_M TMAAMS-VVATLRIPHDAIDHDLARGMDHAPGEPHAQPSGFGVLLHNRTL
MUL_3727|M.ulcerans_Agy99 TMAAMS-VVATLRIPHDAIDHDLARGMDHAPGEPQAQPSGFGVLLHNRTL
Mb2483c|M.bovis_AF2122/97 GMALIS-VLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNREL
Rv2456c|M.tuberculosis_H37Rv GMALIS-VLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNREL
MAV_1023|M.avium_104 GFAVAT-IAAVLAIPGGDIDHHVARGEARAAG--EAPVKAMRVLARSRPL
Mflv_1475|M.gilvum_PYR-GCK ALAAAVAVWAAVAVPR-------LAVLPRTRQTLLDTVRRFSESSFVTPT
MSMEG_1455|M.smegmatis_MC2_155 PVALAGFVGTLRYVPKFPGARMRFDLAGAAALTFGSALLMLGLAIVPQPN
MAB_3449c|M.abscessus_ATCC_199 AALVIVVMLVYFGLRR--------STLLDVADEHHGTPVRLTSALRHRTF
Mvan_5855|M.vanbaalenii_PYR-1 MVFAVLTVAQLFALPQRTAAPAEAKTSVLDDWRVVAANRSFLLFAAAMIG
: : :
MMAR_3804|M.marinum_M MIFAAAVVAFHFANAAMLPLVGQVLALHNRDEGTALMSWCIVAAQVVMVP
MUL_3727|M.ulcerans_Agy99 MIFAAAVVAFHFANAAMLPLVGQVLALHNRDEGTALMSWCIVAAQVVMVP
Mb2483c|M.bovis_AF2122/97 VIFGAAVVAFHFANAAMLPLVGELLALHNRDEGTALMSSCIVAAQVVMVP
Rv2456c|M.tuberculosis_H37Rv VIFGAAVVAFHFANAAMLPLVGELLALHNRDEGTALMSSCIVAAQVVMVP
MAV_1023|M.avium_104 LVLAAAMVLFHLGNAAMLPLYGLAVVATHANPFTTVAS-TVVVAQAVMVP
Mflv_1475|M.gilvum_PYR-GCK LALAAATAALSAG-VGFLPVLGTDFGLS------PVVTGAVVSVLALTTA
MSMEG_1455|M.smegmatis_MC2_155 VSGWAAAGSVALGVVALVWFCFHCARVPNPFVNVRLVTESRFARSALAAF
MAB_3449c|M.abscessus_ATCC_199 LAALMSNFSAGWAIFGIRGALLPLLVVEALHQRPGAAGLVFAAFAAGDVS
Mvan_5855|M.vanbaalenii_PYR-1 SYVLSFQVYLALPLQARDLFPGSDSVVTAMIFVVSGLVAVMGQMRITRWF
.
MMAR_3804|M.marinum_M VAYVTGSRADAWGRKPIFLVAFA----------VLTARGFLYTLSDNSYW
MUL_3727|M.ulcerans_Agy99 VAYVTGSRADAWGRKPIFLVAFA----------VLTACGFLYTLSDNSYW
Mb2483c|M.bovis_AF2122/97 VAYVVGTRADAWGRKPIFLVGFA----------VLTARGFLYTLSDNSYW
Rv2456c|M.tuberculosis_H37Rv VAYVVGTRADAWGRKPIFLVGFA----------VLTARGFLYTLSDNSYW
MAV_1023|M.avium_104 ASLLAMRIAATRGYWPAILIALT----------ALPVRGVLAASVITSWG
Mflv_1475|M.gilvum_PYR-GCK VVQPLAGRAADSGRISLTSGLFTG--------VVVTAAGVAAAALPGLVG
MSMEG_1455|M.smegmatis_MC2_155 AQMFCLGATLLAVPLYLVAHAVSISTAGLVLFTVPVAMAVLGPVVGRRQD
MAB_3449c|M.abscessus_ATCC_199 TAFLAGSWSDDIGRKPLVVAGLV----------VCGSTVVAMGFVSSLPV
Mvan_5855|M.vanbaalenii_PYR-1 AKRWGAGRSLMIGMLILAVSFVP---------LMALPDDTRAGRVAAATA
. : .
MMAR_3804|M.marinum_M LVGVQLLDGIGAGIFGALFPLIVQDLTHGTGHFNISLGAITTA-VGVGAA
MUL_3727|M.ulcerans_Agy99 LVGVQLLDGIGAGIFGALFPLIVQDLTHGTGHFNISLGAITTA-VGVGAA
Mb2483c|M.bovis_AF2122/97 LVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTA-TGIGAA
Rv2456c|M.tuberculosis_H37Rv LVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTA-TGIGAA
MAV_1023|M.avium_104 VIPVQVLDGIGAGMLSVAVPGLVARILDGTGHINVGQGAVMAA-QGLGGA
Mflv_1475|M.gilvum_PYR-GCK LLGGAVVIGVGCGLITPLAFTMLARSTP-EERLGQTMGAAEIG-RECGDA
MSMEG_1455|M.smegmatis_MC2_155 RLGPRLVLRVGLVVLLAVQIALAVTVAQDRLLLGVLIAALVTAGVGIALV
MAB_3449c|M.abscessus_ATCC_199 LVVLSLIGGIGAGLYASPQQAAVADVVGSRGRAGTALATFQMT-SDIGLV
Mvan_5855|M.vanbaalenii_PYR-1 LLGATAVLAVGSAAVFPFEMDTVVSLAGNRLVG--THYGFYNTIVGVGIL
: : :* .
MMAR_3804|M.marinum_M LSNFASGWVVVTAGYN---VAFMSLGAIAGAGFILYLLAMPETASARLAG
MUL_3727|M.ulcerans_Agy99 LSNFASGWVVVTAGYN---VAFMSLGAIAGAGFILYLLAMPETASARLAG
Mb2483c|M.bovis_AF2122/97 LSNLVAGWIVVVAGYD---AAFMSLGALAGAGFLLYLVAMPETVDSDVRV
Rv2456c|M.tuberculosis_H37Rv LSNLVAGWIVVVAGYD---AAFMSLGALAGAGFLLYLVAMPETVDSDVRV
MAV_1023|M.avium_104 LSPVLGGAVAQHLGFR---AAFLLLAGLSLGALIIWVTFAPMLRRAARLP
Mflv_1475|M.gilvum_PYR-GCK AGPLVVAAIAAASTVP---FGFLGLAAVVAASGVGVRRGRGRVGGVG---
MSMEG_1455|M.smegmatis_MC2_155 QTPAATGATRSPAGAEGTGLGLFNLVRFAGSACGAAWVAVALSGPASFPG
MAB_3449c|M.abscessus_ATCC_199 VGPVVAGAIAEHTSYG---WAFVVGGAMPLIAAVAWVFAPETLGRLASPQ
Mvan_5855|M.vanbaalenii_PYR-1 VGNLATGYLMQAAKRVGAPELLWVLLCAIGAVSALALYRLDRRGLLQPAK
. :
MMAR_3804|M.marinum_M R----------------------
MUL_3727|M.ulcerans_Agy99 R----------------------
Mb2483c|M.bovis_AF2122/97 RSRPTLGGK--------------
Rv2456c|M.tuberculosis_H37Rv RSRPTLGGK--------------
MAV_1023|M.avium_104 AAPSDRAGAPPTATADNQAK---
Mflv_1475|M.gilvum_PYR-GCK -----------------------
MSMEG_1455|M.smegmatis_MC2_155 VFIASAVIVALGLAGTFFGPDPA
MAB_3449c|M.abscessus_ATCC_199 VRSMQEVAEDVGGPER-------
Mvan_5855|M.vanbaalenii_PYR-1 STPDRAVAR--------------