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MSDDRVRYARNGDVHLAYRVFGQSGPTVIWVPGWMVSNVDTIDEPGSPYAPGIERASQQVRLVVWDRRGT GLSDPATHLLSLDERLEDLRAIVDSVGLDRAALWGTSEGGAVSILFAATYPDRVGLLSLFGTAARFSQDL PDFPWGFTPAEVQSQLCAIEDDWGRGALAELFYGQAAEVPGMRELFGRLQRSVSSPSMAKLWWQAFMATD VRAVLGSIRVPTLVLARPGDQLVPLESSAALAAAIPNAQFRLLPPGPHTPFDIIDDLAREVLDFFTGESG APADERVLKTVLFTDIVSSTEKLSTMGDTAWRHQLNGHDSVVDNLLLRYGGTRAKHTGDGVFALFDAPTK AARCALQLVPALAALNIAIRAGIHTGECERRGQEWSGMAVHIGARIGVLADAGEVFASRTVRDLTAGSGL TFESLGPQQLKGLPEQIEIYRVSAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3505 | - | - | 100% (445) | hydrolase |
| M. marinum M | MMAR_0286 | lipJ | 2e-64 | 36.82% (440) | lignin peroxidase LipJ |
| M. marinum M | MMAR_4340 | - | 1e-16 | 32.35% (170) | hypothetical protein MMAR_4340 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1935c | lipJ | 3e-60 | 36.43% (442) | lignin peroxidase LIPJ |
| M. gilvum PYR-GCK | Mflv_3121 | - | 5e-25 | 33.20% (259) | transcriptional regulator, CadC |
| M. tuberculosis H37Rv | Rv1900c | lipJ | 9e-60 | 36.20% (442) | lignin peroxidase LIPJ |
| M. leprae Br4923 | MLBr_01399 | - | 4e-14 | 30.18% (169) | hypothetical protein MLBr_01399 |
| M. abscessus ATCC 19977 | MAB_2330 | - | 9e-13 | 30.85% (188) | putative purine cyclase-like protein |
| M. avium 104 | MAV_5228 | - | 1e-62 | 35.90% (454) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_4477 | - | 5e-69 | 37.97% (453) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_1244 | - | 2e-17 | 33.74% (163) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4838 | lipJ | 3e-62 | 36.14% (440) | lignin peroxidase LipJ |
| M. vanbaalenii PYR-1 | Mvan_3415 | - | 5e-24 | 32.82% (259) | transcriptional regulator, CadC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1935c|M.bovis_AF2122/97 MAQAPHIHRTRYAKCGDMDIAYQVLGDGPTDLLVLPGPFVP-IDSIDDEP
Rv1900c|M.tuberculosis_H37Rv MAQAPHIHRTRYAKCGDMDIAYQVLGDGPTDLLVLPGPFVP-IDSIDDEP
MUL_4838|M.ulcerans_Agy99 MSQAPRTPRTRYARCGDLDIAYQVIGDHPIDLLVIPGASIP-VDTIDSEP
MAV_5228|M.avium_104 MPGFSGTPRTRYASCGDTDIAYQVLGDGPIDLVLLPGPSIP-IDSVDAEP
MSMEG_4477|M.smegmatis_MC2_155 ------MAETSYASCGDLSLAYQLFGDGPIPLVFVGPFVGH-VELFWTVP
MMAR_3505|M.marinum_M ----MSDDRVRYARNGDVHLAYRVFGQSGPTVIWVPGWMVSNVDTIDEPG
MLBr_01399|M.leprae_Br4923 -----------------------------------------------MPP
MAB_2330|M.abscessus_ATCC_1997 ---------------------------------------------MDVEP
Mflv_3121|M.gilvum_PYR-GCK ------------------------MTSAD-ALSSSPRVWRWDDYVLDLGR
Mvan_3415|M.vanbaalenii_PYR-1 --MPPTAGADLAATRGCRHRYCCRVTSADSALSPHRRVWRWDDFVLDVGC
TH_1244|M.thermoresistible__bu --------------------------------------------------
Mb1935c|M.bovis_AF2122/97 SLYR-FHRRLASFSRVIRLDHRGVGLSSRLAAITTLGPKFWAQDAIAVMD
Rv1900c|M.tuberculosis_H37Rv SLYR-FHRRLASFSRVIRLDHRGVGLSSRLAAITTLGPKFWAQDAIAVMD
MUL_4838|M.ulcerans_Agy99 SMYR-FHRRLASFSRLIRFDHRGVGLSSRVSSPDALGPRFWAEDAIAVMD
MAV_5228|M.avium_104 SMYR-FHRRLAAFARVIRLDQRGIGLSSRVPSVDVIGPEFWARDVVSVMD
MSMEG_4477|M.smegmatis_MC2_155 EFKS-FFDQLASFCRVAIFDKAGTGLSDPVPKVRTLDDR--AAEIEAVMD
MMAR_3505|M.marinum_M SPYAPGIERASQQVRLVVWDRRGTGLSDPATHLLSLDER--LEDLRAIVD
MLBr_01399|M.leprae_Br4923 SAKS----TYP-------------GQVEGAPHDGTPSAPQEPDEDTVTVP
MAB_2330|M.abscessus_ATCC_1997 SGLD----AEPDGEFDSGIRKRRRGRTRGPVRHDSAQVTDGIDTTADEVP
Mflv_3121|M.gilvum_PYR-GCK YELRAGDSVIRVEPQVFDVLTQLVSHHDRCVSKEELFDTVWGGRFVGEAA
Mvan_3415|M.vanbaalenii_PYR-1 YELRRGDTMIRVEPQVFDVLAQLVSNHGRFVSKEELFDTVWGGRFVGEAA
TH_1244|M.thermoresistible__bu ------------------VAARPLPLAVAAAPGSPIPRRVGQDGAVTQIA
Mb1935c|M.bovis_AF2122/97 AVGCEQATIFAPSFHAMNGLVLAADYPERVRSLIVVN-----GSARPLWA
Rv1900c|M.tuberculosis_H37Rv AVGCEQATIFAPSFHAMNGLVLAADYPERVRSLIVVN-----GSARPLWA
MUL_4838|M.ulcerans_Agy99 AAGCQQATILASGFTATTALVLAADYPERVRSLVLIN-----ASARTLHA
MAV_5228|M.avium_104 AVGCERATVVAPSFTSMTGLVLAADYPDRVSSLVIIN-----GAARTVYA
MSMEG_4477|M.smegmatis_MC2_155 AVGFDDAVVLAMSEGGPASILFAANRPGRVRTLVAYGSFATMAGCRWEDL
MMAR_3505|M.marinum_M SVGLDRAALWGTSEGGAVSILFAATYPDRVGLLSLFG----TAARFSQDL
MLBr_01399|M.leprae_Br4923 APALIRRSSVSMP-NAAQWLHTTNRSPRLVAMVRRAR----------RLL
MAB_2330|M.abscessus_ATCC_1997 STESASRHFARASRTAGSWFRKMDRDPAVVAALRRAR----------RSL
Mflv_3121|M.gilvum_PYR-GCK LTSRIKAVRRALGDDGEAQRYIRTVRGRGYRFVGTLHG---EDSATPDEA
Mvan_3415|M.vanbaalenii_PYR-1 LTSRIKAVRRALGDDGEAQRYIRTVRGRGYQFVGRLLD---DGTAPAPTA
TH_1244|M.thermoresistible__bu IVVVALAGLALAEAVALAVLWGRLRRERRAADELRRR-------------
.
Mb1935c|M.bovis_AF2122/97 PDYPVGAQVRRADPF-LTVALEPDAVEQGFDVLSIVAPTVAGDDVFRAWW
Rv1900c|M.tuberculosis_H37Rv PDYPVGAQVRRADPF-LTVALEPDAVERGFDVLSIVAPTVAGDDVFRAWW
MUL_4838|M.ulcerans_Agy99 PDYELGIRSNTAEPF-LTLGTDPDAVEQGFDVLRIMAPSVAHDDAFRHWW
MAV_5228|M.avium_104 PDYPMGARIETLDPY-TTVAVDPDAVDQGFDMLGLIAPSVAGDAAFRSWW
MSMEG_4477|M.smegmatis_MC2_155 DGDPVDIRARSVAEMGDEYAPTVEQVIHFQEQARAVRGQWGSGAAVRCAM
MMAR_3505|M.marinum_M PDFPWGFTP-------AEVQSQLCAIEDDWGRGALAELFYGQAAEVPGMR
MLBr_01399|M.leprae_Br4923 PGDPD---------------------------------------------
MAB_2330|M.abscessus_ATCC_1997 PGDPY---------------------------------------------
Mflv_3121|M.gilvum_PYR-GCK SVEHV---VRETPRQHIAFARAADGVRLAYAESGDGPPLVKAANWMTHLG
Mvan_3415|M.vanbaalenii_PYR-1 APEPAPEPVPEPPRQHIAFTRAADGVRLAYAVSGEGRPLVRAANWMTHLG
TH_1244|M.thermoresistible__bu --------------------------------------------------
Mb1935c|M.bovis_AF2122/97 DLAGNR---------AGPPSMARAVSKVIAEADVRDVLGHIEAPTLILHR
Rv1900c|M.tuberculosis_H37Rv DLAGNR---------AGPPSIARAVSKVIAEADVRDVLGHIEAPTLILHR
MUL_4838|M.ulcerans_Agy99 DLAGNR---------AASPSTARAFINAVQASDARDSLPHITAPTLILHR
MAV_5228|M.avium_104 DAAGNR---------AASPSMARAMILSIRHADVRDRLARITTPTLILHR
MSMEG_4477|M.smegmatis_MC2_155 PSMGSMRQLGMFERLCASPGMARATFEAAFRIDVRPILPTIAAPTLVIHA
MMAR_3505|M.marinum_M ELFGRLQR------SVSSPSMAKLWWQAFMATDVRAVLGSIRVPTLVLAR
MLBr_01399|M.leprae_Br4923 --------------------------------------------------
MAB_2330|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3121|M.gilvum_PYR-GCK YDSESP----------------VWRHGVREMSLRYRFIRYDERGCGLSDW
Mvan_3415|M.vanbaalenii_PYR-1 YDIESP----------------VWRHWVRDMSLRHKFIRYDERGCGLSDW
TH_1244|M.thermoresistible__bu -----------------------------------------------LDT
Mb1935c|M.bovis_AF2122/97 VGSTYIPVGHGRYLAEHIAGSRLVELPGTDTLYWVGDTGPMLDEIEEFIT
Rv1900c|M.tuberculosis_H37Rv VGSTYIPVGHGRYLAEHIAGSRLVELPGTDTLYWVGDTGPMLDEIEEFIT
MUL_4838|M.ulcerans_Agy99 VGTKFVPVEHGRYLAEHIAGSRLVELPGSDSLYWVGDTAALLDEVEEFIT
MAV_5228|M.avium_104 TDCVFTSVDHGRYLAEHIAGSRFVSLPGEDTLYWVGDTGPMLDEIEEFIT
MSMEG_4477|M.smegmatis_MC2_155 RDDPAVPVQCSRYLADHISGARWLEVDGVDHAPWFTEADRVLTEIEEFVT
MMAR_3505|M.marinum_M PGDQLVPLESSAALAAAIPNAQFRLLP-PGPHTPFDIIDDLAREVLDFFT
MLBr_01399|M.leprae_Br4923 FGDPLSTAGEGGPRAAARAADRLLGDRGAASREVSLSVLQVWQALTEAIA
MAB_2330|M.abscessus_ATCC_1997 FGDPLSTSGFGGASAVARAADRLVTDRDTAVREFGFGALQIWQAFTEKVS
Mflv_3121|M.gilvum_PYR-GCK DVGDFTFDDWVADLETVVDAVGLDRFHLMGVSQGGAVAVAYAARHPDKVS
Mvan_3415|M.vanbaalenii_PYR-1 EVGAFTFDDWVTDLESVVEAVGLERFPLLGVSQGGAVAVAYAARHPDRVT
TH_1244|M.thermoresistible__bu RTTLMAGGREAVRTVWQTANILRTDGLGAAARSSIEDLADWAEVERPDLA
.:
Mb1935c|M.bovis_AF2122/97 GVRGG-ADAERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHE
Rv1900c|M.tuberculosis_H37Rv GVRGG-ADAERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHE
MUL_4838|M.ulcerans_Agy99 GVRGG-FVTERVLTAVMFTGIVGSTQRAATVGDLRWRDLLDNHDNLVRHE
MAV_5228|M.avium_104 GVRGG-SEAERLLTTIVFTDIVGSTERAAALGDYRWRDLLDNHDRIVRHE
MSMEG_4477|M.smegmatis_MC2_155 GNHAAPHNSHRALRTVLFTDIVASTQHAASNGDERWRAVLQRFGEVTEEL
MMAR_3505|M.marinum_M GESGA-PADERVLKTVLFTDIVSSTEKLSTMGDTAWRHQLNGHDSVVDNL
MLBr_01399|M.leprae_Br4923 RRPVN------PEVTLVFTDLVGFSGWSLQAGDEATLALLRQVARAVESP
MAB_2330|M.abscessus_ATCC_1997 KQPAN------REVTLVFTDLVGFSGWALEAGDEATLKLLRRVASVSEPP
Mflv_3121|M.gilvum_PYR-GCK RLVLCGAYARGRAVRALSDDEKRAAALDLELARVGWGRDDPAFRQVFAAQ
Mvan_3415|M.vanbaalenii_PYR-1 RLVLCGAYARGRVVRAMNDDEKRAAALDLDLARVGWGRDDPAFRQVFAAQ
TH_1244|M.thermoresistible__bu RLAAN------GKVVILFSDIEGSTALNNRIGDRAWVRLIDRHSRLVRRF
: . : .
Mb1935c|M.bovis_AF2122/97 IQRFGGREVNTAGDGFVATFTSPSAAIACADDIVDAVAALGIE-----VR
Rv1900c|M.tuberculosis_H37Rv IQRFGGREVNTAGDGFVATFTSPSAAIACADDIVDAVAALGIE-----VR
MUL_4838|M.ulcerans_Agy99 IQRFGGREVNTAGDGFVATFSSPSAAINCADAVVDAVAVLGIE-----VR
MAV_5228|M.avium_104 LQRFGGREVNTAGDGFVATFSSPSAAISCADALVDAVAALGIE-----VR
MSMEG_4477|M.smegmatis_MC2_155 SGRFGGVVVKSTGDGHLSTFEGPTHAIRYAEALRSDAETLGIQ-----IR
MMAR_3505|M.marinum_M LLRYGGTRAKHTGDGVFALFDAPTKAARCALQLVPALAALNIA-----IR
MLBr_01399|M.leprae_Br4923 LLDAGGHIVKRMGDGIMAVFRDPSVAVQAVLAATEAMKSVEVGGYTPRIR
MAB_2330|M.abscessus_ATCC_1997 LLSAGGQVVKRMGDGIMAVFDDPVTALRAIIPARDALKNVEIQGYTPVMR
Mflv_3121|M.gilvum_PYR-GCK FLPDG----TRADWAAFDQLQRRTTSPENAVHFLEEFARIDVR----DLC
Mvan_3415|M.vanbaalenii_PYR-1 FLPDG----TRADWAAFDQLQRRTTSPENAVRFLEEFAHIDVR----DQC
TH_1244|M.thermoresistible__bu VKKHDGYVIKSQGDGFMVAFARPEQAVRCSVELQRALRKRPDR---IRVR
. . . . . : :
Mb1935c|M.bovis_AF2122/97 IGIHAGEVEVRDASHGTDVAGVAVHIGARVCALAGPSEVLVSSTVRDIVA
Rv1900c|M.tuberculosis_H37Rv IGIHAGEVEVRDASHGTDVAGVAVHIGARVCALAGPSEVLVSSTVRDIVA
MUL_4838|M.ulcerans_Agy99 VGIHAGEVEVR----GADVADLAVHIGARVCALAGSSEVLVSSTVRDIVT
MAV_5228|M.avium_104 VGIHAGEVEVRGAR-KDDIAGMAVHIGARVAALAGPGEVLVSSTLRDIVT
MSMEG_4477|M.smegmatis_MC2_155 AAIHTGECELLG----DDIGGIAVHIAARILGQARAGEILVSRTVRDLVV
MMAR_3505|M.marinum_M AGIHTGECERRG----QEWSGMAVHIGARIGVLADAGEVFASRTVRDLTA
MLBr_01399|M.leprae_Br4923 VGIHTGRPQRLA----ADWLGVDVNIAARVMERATKGGIMISGPTLDLIP
MAB_2330|M.abscessus_ATCC_1997 IGIHAGTPQRIG----SDWLGVDVNIAARVMESAAKGGLAISQPALAKVP
Mflv_3121|M.gilvum_PYR-GCK ARVQCPTLVLHS----RDDHRVPMRYGEELASLIPDARLVALSSNNHLLT
Mvan_3415|M.vanbaalenii_PYR-1 GQVRCPTLILHS----RDDHRVPMRYGEELAALIPDARLVALSSNNHLLT
TH_1244|M.thermoresistible__bu IGIHLGRSVRRG----DDLFGRNVALAARVAGAAEGGEVLVSQAVRDALN
:: : : . .: . : .
Mb1935c|M.bovis_AF2122/97 GSRHRFAERGEQELK---------GVPGRWRLCVL---------------
Rv1900c|M.tuberculosis_H37Rv GSRHRFAERGEQELK---------GVPGRWRLCVL---------------
MUL_4838|M.ulcerans_Agy99 GSSHRFAERGEHELK---------GVPGRWRLCAL---------------
MAV_5228|M.avium_104 GSRHRFGDRGETALK---------GVPGQWRLYRL---------------
MSMEG_4477|M.smegmatis_MC2_155 GSGTSFADRGNVELR---------GVPGTWQLLAVGDGAGGGSPAGSVEA
MMAR_3505|M.marinum_M GSGLTFESLGPQQLK---------GLPEQIEIYRVSAA------------
MLBr_01399|M.leprae_Br4923 QSDLKELGIITRRVRKPMFTSKFTGIPPDMVIYRIKAR------------
MAB_2330|M.abscessus_ATCC_1997 LAFLDHMGLTPTPVRRPLFSSRPAGVPENMKMYLLETR------------
Mflv_3121|M.gilvum_PYR-GCK ATEPAWQVFCAEVAA----------------FLV----------------
Mvan_3415|M.vanbaalenii_PYR-1 GAEPAWRVFCDEVET----------------FLAV---------------
TH_1244|M.thermoresistible__bu SAGDAGSDEVAGFDVDDGREVSLKGFPGRHRLFAVRG-------------
: :
Mb1935c|M.bovis_AF2122/97 -----------------------------------MRDDATRTR------
Rv1900c|M.tuberculosis_H37Rv -----------------------------------MRDDATRTR------
MUL_4838|M.ulcerans_Agy99 -----------------------------------VREHLTGQR------
MAV_5228|M.avium_104 -----------------------------------LREHAAAER------
MSMEG_4477|M.smegmatis_MC2_155 LLAAEPTPAARTATRRADRAVAAVAKRTPWALRGVARLTMSATRR-----
MMAR_3505|M.marinum_M --------------------------------------------------
MLBr_01399|M.leprae_Br4923 -----------------------------------RELTASDETAQTNSL
MAB_2330|M.abscessus_ATCC_1997 -----------------------------------RQLPAPGDDGRV---
Mflv_3121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3415|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1244|M.thermoresistible__bu -----------------------------------QAGFRPRPRPE----
Mb1935c|M.bovis_AF2122/97 -
Rv1900c|M.tuberculosis_H37Rv -
MUL_4838|M.ulcerans_Agy99 -
MAV_5228|M.avium_104 -
MSMEG_4477|M.smegmatis_MC2_155 -
MMAR_3505|M.marinum_M -
MLBr_01399|M.leprae_Br4923 T
MAB_2330|M.abscessus_ATCC_1997 -
Mflv_3121|M.gilvum_PYR-GCK -
Mvan_3415|M.vanbaalenii_PYR-1 -
TH_1244|M.thermoresistible__bu -