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ISTTSGQVVALARTMRDLVRAEAGESERRRTLTDKIVNEMWSTGLMSAFNPTAAGGTEPAFAEMIETWIE MAWQDGSFGWIGIANLPSTFAAATYLPDDGFAEVFSAADNRVTMGGQFFPNGQGSAVDGGYRLSGSWSFG SGTGHAQYIAAGFFPMDDGDMRWVREGVPDMQVAVVPREQITFNDGWFVQGLKGTGSYDYSAEDVFVPQG RTFGLFAREPRRGSSPATRMGLMPVTAAGHASWALGVAKSMLDDVTELAATKYRMSDMAALASRPTFQKG LAHHVAAWRAARLLVLDAFTTAEAAVGAGQELTPTLRSDMRAAAVFATDTARSCAEWAHLVAGTSSIREG SRLERAFRDMYTGTQHAFISEKVAIDCAQIWLGIVEDQFGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3457 | - | - | 100% (392) | hypothetical protein MMAR_3457 |
| M. marinum M | MMAR_1556 | - | 7e-41 | 32.96% (361) | dehydrogenase |
| M. marinum M | MMAR_5065 | - | 1e-22 | 25.25% (396) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 6e-38 | 30.73% (371) | hypothetical protein Mb3121c |
| M. gilvum PYR-GCK | Mflv_3440 | - | 0.0 | 80.94% (383) | acyl-CoA dehydrogenase type 2 |
| M. tuberculosis H37Rv | Rv3094c | - | 6e-38 | 30.73% (371) | hypothetical protein Rv3094c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0315 | - | 2e-34 | 29.17% (384) | hypothetical protein MAB_0315 |
| M. avium 104 | MAV_2767 | - | 0.0 | 82.10% (391) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0198 | - | 9e-28 | 27.59% (377) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_4288 | - | 1e-26 | 30.92% (262) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. ulcerans Agy99 | MUL_3474 | - | 7e-39 | 32.35% (371) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3194 | - | 0.0 | 84.11% (384) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3121c|M.bovis_AF2122/97 -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
Rv3094c|M.tuberculosis_H37Rv -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
MUL_3474|M.ulcerans_Agy99 MTEPPSLPGVLMNQPDLSAAPLRRADSEMEDLAEKIALTAREMSAEIDRD
MMAR_3457|M.marinum_M --------------------MISTTSGQVVALARTMRDLVRAEAGESERR
MAV_2767|M.avium_104 ------------------MTSIADTDDRVVALARGMRDLVQDQAAESERM
Mflv_3440|M.gilvum_PYR-GCK --------------------------MTAVEQAHALRDVVGAHAAESEQL
Mvan_3194|M.vanbaalenii_PYR-1 ----------------------------MVERARGMRDLVRAQAAESEQI
MSMEG_0198|M.smegmatis_MC2_155 -------------------MTTQVQTHDVLDLPGALRASIEASVEEADGL
MAB_0315|M.abscessus_ATCC_1997 ------------------MTSSTAVQPDAVQRARELAPAIAARALEAERL
TH_4288|M.thermoresistible__bu ---------------------------------------MQLLTVHAHTI
. .
Mb3121c|M.bovis_AF2122/97 RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
Rv3094c|M.tuberculosis_H37Rv RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
MUL_3474|M.ulcerans_Agy99 RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
MMAR_3457|M.marinum_M RTLTDKIVNEMWSTGLMSAFNPTAAGGTEPAFAEMIETWIEMAWQDGSFG
MAV_2767|M.avium_104 RTLTPAIVDAMWASGLMSAFNTIEAGGVEPSFTEMIETWIEMAWQDGSFG
Mflv_3440|M.gilvum_PYR-GCK RTLAPAVVDAMWSSGLMSAFNPSAAGGSEPTFAEMIETWIEMAWQDGSFG
Mvan_3194|M.vanbaalenii_PYR-1 RTMTPAIVEAMWSTGLMSAFNPAPAGGVEPSFAEMIETWIEMAWQDGSFG
MSMEG_0198|M.smegmatis_MC2_155 GDIPSRLHDELRDAGAFRLLTPRELGGWAAPLPTALSVYEKFGRIDGSVG
MAB_0315|M.abscessus_ATCC_1997 RRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGSTA
TH_4288|M.thermoresistible__bu ASYSPQLQDEIWGGGPD---------------------------------
. : *
Mb3121c|M.bovis_AF2122/97 WCVSIAITSALLVA-YLPARSREEMFGG----GRGVAAGVWAPRGTARSV
Rv3094c|M.tuberculosis_H37Rv WCVSIAITSALLVA-YLPARSREEMFGG----GRGVAAGVWAPRGTARSV
MUL_3474|M.ulcerans_Agy99 WCVSIAITSALLVA-YLPASSRDEMFGA----GRSVAAGVWAPRGKAKSV
MMAR_3457|M.marinum_M WIGIANLPSTFAAATYLPDDGFAEVFSAA--DNRVTMGGQFFPNGQGSAV
MAV_2767|M.avium_104 WVGIANLPSSFAAAAYLPDDGFAEVFTAH--DNHVTMGGQFFPNGQGAAV
Mflv_3440|M.gilvum_PYR-GCK WVGIANFPSSFAAASYLPDSGFAEVFTAN--DNRVTMGGQFFPNGQGVAV
Mvan_3194|M.vanbaalenii_PYR-1 WVGIANLPSSFAAATYLPDGGFAEVFTAN--HNRVTMGGQFFPNGQGHAV
MSMEG_0198|M.smegmatis_MC2_155 LLVWN--TNFGFIGAMLPETGNKRIWGTG--VEPVFANSGMP--GTATPT
MAB_0315|M.abscessus_ATCC_1997 WTFCIYGIHNWLAG-LFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPV
TH_4288|M.thermoresistible__bu ----------------------------------TLVCSSVAPIGKSEQV
. * . .
Mb3121c|M.bovis_AF2122/97 DGGVVVSGRWPFCSGINHADIMFAGCFVDDR----------QVPSVVALN
Rv3094c|M.tuberculosis_H37Rv DGGVVVSGRWPFCSGINHADIMFAGCFVDDR----------QVPSVVALN
MUL_3474|M.ulcerans_Agy99 DGGVVVSGRWPFCSGINHADMMFAGCFVEGQ----------PVPSVVALP
MMAR_3457|M.marinum_M DGGYRLSGSWSFGSGTGHAQYIAAGFFPMDDGDMRWVREGVPDMQVAVVP
MAV_2767|M.avium_104 DGGYLVSGAWNFGSGIGHSQYVAAGFLPMDDGEMRWISEGFPEMRVAVIP
Mflv_3440|M.gilvum_PYR-GCK DGGYRLTGAWSFGSGTGHAEYVAAGFFPMVDGEMRWAGEGIPDMQVAVVP
Mvan_3194|M.vanbaalenii_PYR-1 DGGYRLTGSWSFGSGTGHAEYVAAGFLPMVDGEIRWAGDGVPDMQVAVVP
MSMEG_0198|M.smegmatis_MC2_155 NGGFQLSGHWKIVTGIRSATWIVVVGIVTGDTN------GAPDVRLFAVP
MAB_0315|M.abscessus_ATCC_1997 EGGYKITGRWQFGSGVWHSSWASVAAVVQHEEP-----PKYPDLRTFMIP
TH_4288|M.thermoresistible__bu AGGIRLSGRYAWSSGCEHAHWAMLGLLLPGIDG-------VPEPHLAVVP
** ::* : :* : . :
Mb3121c|M.bovis_AF2122/97 KDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSV------FDG--P
Rv3094c|M.tuberculosis_H37Rv KDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSV------FDG--P
MUL_3474|M.ulcerans_Agy99 KDDLRALDTWHTLGLCGTGSHDCVAEEVFVPADRVFSV------FDG--P
MMAR_3457|M.marinum_M REQITFNDGWFVQGLKGTGSYDYSAEDVFVPQGRTFGL------FAREPR
MAV_2767|M.avium_104 REQISFDDGWYVQGLKGTGSYDYSARDVFVPAARTFEL------FTRAPF
Mflv_3440|M.gilvum_PYR-GCK RDQVSFKDGWHVQGLRGTGSYDYAIDDVFVPHDRTFAL------FTREPK
Mvan_3194|M.vanbaalenii_PYR-1 RAEVSFKDGWHVQGLKGTGSYDYSIDDVFVPHDRTFAL------FTREPR
MSMEG_0198|M.smegmatis_MC2_155 TDQIDIQDTWNVTGLRATGSRDVVIDDVFVPEDLATRL------DAP--V
MAB_0315|M.abscessus_ATCC_1997 RSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAE
TH_4288|M.thermoresistible__bu RSDYTIQDTWYSMGLKGTGSHDLVVEDAFVPSYRIESFSALNHGTARGFG
: * * ** .*** * :.*** .
Mb3121c|M.bovis_AF2122/97 IVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTL
Rv3094c|M.tuberculosis_H37Rv IVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTL
MUL_3474|M.ulcerans_Agy99 TIDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKRTL
MMAR_3457|M.marinum_M RGSSPATRMGLMPVTAAGHASWALGVAKSMLDDVTELAATKYRMSDMAAL
MAV_2767|M.avium_104 RGASPATRMGLMPVTAAGHASWALGVAKSMLDDVQELAATKFRMSDMASL
Mflv_3440|M.gilvum_PYR-GCK RGSSPAGRMGMMPVTAAGHAAWALGVAKSMLDDVAELAATKFRMSDMASL
Mvan_3194|M.vanbaalenii_PYR-1 RGSSPATRMGMMPVTAAGHAAWALGVAKSMLDDVSELAATKFRMSDMAAL
MSMEG_0198|M.smegmatis_MC2_155 NTDSPVYRGFIGNLVFGGCAAVTLGIAAHMIEETVTLVRSKASVVGG-VV
MAB_0315|M.abscessus_ATCC_1997 LHGSAIYRIPLFCALSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQ
TH_4288|M.thermoresistible__bu THAAPIYRLPFAPVFAIGFSAIALGAAEAMRDLYKERLASRVRAYTGAKV
. * . .: ::* * : :
Mb3121c|M.bovis_AF2122/97 AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPV-------
Rv3094c|M.tuberculosis_H37Rv AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPV-------
MUL_3474|M.ulcerans_Agy99 AERSATQTAVATAEAALGAARALFYEAIDSAWQASHNPDPVPVPVPVPVP
MMAR_3457|M.marinum_M ASRPTFQKGLAHHVAAWRAARLLVLDAFTTAEAAVGAGQELTP-------
MAV_2767|M.avium_104 ASRPTFQKGLAHHRAAWRAARLLVLDAFTTAEAAVAAGQELTP-------
Mflv_3440|M.gilvum_PYR-GCK ASRPTFQKDLAHHVAAWRAARLLVLDAFTGAEGAVAAGAELTP-------
Mvan_3194|M.vanbaalenii_PYR-1 ASRPTFQKGLAHHVAAWRAARLLVLDAFGTAEAAVAGGDDLTP-------
MSMEG_0198|M.smegmatis_MC2_155 ADATRTQYLVAKAQASVDAARLLLLS---TASELADAGDQLTL-------
MAB_0315|M.abscessus_ATCC_1997 SKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTT-------
TH_4288|M.thermoresistible__bu AESAPALMRLAESEHELRSAYRMLRQDWNDLDALANSGRLATA-------
:. . . :* :. . .
Mb3121c|M.bovis_AF2122/97 ---TMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
Rv3094c|M.tuberculosis_H37Rv ---TMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
MUL_3474|M.ulcerans_Agy99 VPVALRNRLRLAATHAARTSADVVRTMYDLAGSSAIYDGSPLQRRFRDAF
MMAR_3457|M.marinum_M ---TLRSDMRAAAVFATDTARSCAEWAHLVAGTSSIREGSRLERAFRDMY
MAV_2767|M.avium_104 ---ALRADMRVAAVYATDTARGCAEWAHLVAGTSSIREGSRLERAFRDIY
Mflv_3440|M.gilvum_PYR-GCK ---TMRADMRVAAVFATDTARGCAEWAHLAAGTTSIREGSRLERAFRDIY
Mvan_3194|M.vanbaalenii_PYR-1 ---TLRADMRVAAVFATDTARACAEWAHLVAGTSSIREGSRLERAFRDVY
MSMEG_0198|M.smegmatis_MC2_155 ---DQRAAHRAAITHAAEVSRIALVDMYNLAGSSALYRTNTIERIFRDGM
MAB_0315|M.abscessus_ATCC_1997 ---GDRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVN
TH_4288|M.thermoresistible__bu ---DELVNWRTNQSYVTNVCVRAADRLFEASGGAAVRDENPMQRFWRDIH
* . . .. .* :: ::* **
Mb3121c|M.bovis_AF2122/97 TATAHFQVN-EASRELPGRVLLDQPADVSML
Rv3094c|M.tuberculosis_H37Rv TATAHFQVN-EASRELPGRVLLDQPADVSML
MUL_3474|M.ulcerans_Agy99 TATAHFQVN-EASRELPGRVLLGQHCDTSML
MMAR_3457|M.marinum_M TGTQHAFIS-EKVAIDCAQIWLGIVEDQFGL
MAV_2767|M.avium_104 TGTQHAFIS-EKVAIDVAQIWLGIIEDQPGL
Mflv_3440|M.gilvum_PYR-GCK TGTQHAFIS-EKVAIDAAQVWLGVVEDQFGL
Mvan_3194|M.vanbaalenii_PYR-1 TGTQHAFIS-EKVAIDAAQVWLGVVEDQFGL
MSMEG_0198|M.smegmatis_MC2_155 AATQHANQS-ALFMEGAGRVRLGMDHGLPLF
MAB_0315|M.abscessus_ATCC_1997 TLSTHVVYDTDSAYELYGRVELGLPPGSVAF
TH_4288|M.thermoresistible__bu AGAAHAYSDYDVAAQVLGSHMAQVAVDGIF-
: : * . . .