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M. thermoresistible (build 8) TH_4288 (-)

annotation: Acyl-CoA dehydrogenase, type 2, C-terminal domain
coordinates: 3110986 - 3111909
length: 308

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4288--100% (308)Acyl-CoA dehydrogenase, type 2, C-terminal domain
M. thermoresistible (build 8)TH_1742-2e-5739.60% (298) POSSIBLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_2929-7e-4432.99% (291) PUTATIVE acyl-CoA dehydrogenase, C- domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3601c-3e-5538.93% (298) oxidoreductase
M. gilvum PYR-GCKMflv_1463-6e-5137.04% (297) acyl-CoA dehydrogenase type 2
M. tuberculosis H37RvRv3570c-3e-5538.93% (298) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0584-6e-5036.67% (300) hypothetical protein MAB_0584
M. marinum MMMAR_5065-3e-5337.58% (298) acyl-CoA dehydrogenase
M. avium 104MAV_0591-2e-5638.93% (298) pigment production hydroxylase
M. smegmatis MC2 155MSMEG_6038-1e-5037.00% (300) pigment production hydroxylase
M. ulcerans Agy99MUL_4141-7e-5337.25% (298) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1Mvan_5308-2e-5037.37% (297) acyl-CoA dehydrogenase type 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1463|M.gilvum_PYR-GCK          MTSIEQR----DAQTVLAGVNDLLPRIAKRSAAAEELRRLPDETVAELDE
Mvan_5308|M.vanbaalenii_PYR-1       MTSIQQR----DAQSVLAGIDDLLPRIAKRSQAAEELRRLPDETVTELDE
MSMEG_6038|M.smegmatis_MC2_155      MTSIEQR----DVQAVLAGVDDLLPKLRERAQAAEELRQIPQESIDELDE
Mb3601c|M.bovis_AF2122/97           MTSIQQR----DAQSVLAAIDDLLPEIRDRAQATEDLRRLPDETVKALDD
Rv3570c|M.tuberculosis_H37Rv        MTSIQQR----DAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDD
MMAR_5065|M.marinum_M               MTTIQQR----DAQSVLAAIDDLLPQLRERAQATEDLRRLPDETVQALED
MUL_4141|M.ulcerans_Agy99           MTTIQQR----DAQSVLAAIDDLLPQLRERAQATEDLRRLPDETVQALED
MAV_0591|M.avium_104                MTSIQQR----DAQSVLAGIDDLLPRIRERAQATEDLRRLPDETVADLQD
MAB_0584|M.abscessus_ATCC_1997      MTTTEQREHSDEVLSVLSQIDDLLPTLRKRAQETEDLRRLPDATVAELQE
TH_4288|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_1463|M.gilvum_PYR-GCK          VGFFKLLQPEQWGGLQCDPTLFYEAVRRIASACGSTGWVSSIIGVHNWHL
Mvan_5308|M.vanbaalenii_PYR-1       VGFFKLLQPEQWGGLQCDPTIFYEAVRRIASACGSTGWVASIIGVHNWHL
MSMEG_6038|M.smegmatis_MC2_155      IGFFKLLQPEQWGGLQADPTVFYEAVRRLASACGSTGWVASIIGVHNWHL
Mb3601c|M.bovis_AF2122/97           VGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHL
Rv3570c|M.tuberculosis_H37Rv        VGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHL
MMAR_5065|M.marinum_M               VGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSIIGVHNWHL
MUL_4141|M.ulcerans_Agy99           VGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSIIGVHNWHL
MAV_0591|M.avium_104                VGFFTLLQPEQWGGLQCDPTLFYEAVRRLASACGSTGWVSSIIGVHNWHL
MAB_0584|M.abscessus_ATCC_1997      IGFFKLLQPSQWGGYETAPTTFYEAVRRLGSACGSTGWVASIIGVHNWHL
TH_4288|M.thermoresistible__bu      ---------------------------------------MQLLTVHAHTI
                                                                            .:: **   :

Mflv_1463|M.gilvum_PYR-GCK          ALFDQKAQEDVWGDDPTVRVSSSYAPMGAGTVVDG--GYLVSGAWQWSSG
Mvan_5308|M.vanbaalenii_PYR-1       ALFDQQAQEEVWGSDPTVRVSSSYAPMGAGTVVDG--GYLVSGAWQWSSG
MSMEG_6038|M.smegmatis_MC2_155      ALFDQKAQDEVWGDDPTVRVSSSYAPMGAGVVTETGDGYIVNGAWQWSSG
Mb3601c|M.bovis_AF2122/97           ALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDG--GYLVNGSWNWSSG
Rv3570c|M.tuberculosis_H37Rv        ALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDG--GYLVNGSWNWSSG
MMAR_5065|M.marinum_M               ALFDQLAQEEVWGSDPKTRISSSYAPMGAGVVVDG--GYLVNGSWNWSSG
MUL_4141|M.ulcerans_Agy99           ALFDQLAQEEVWGSDPKTRISSSYAPMGAGVVVDG--GYLVNGSWNWSSG
MAV_0591|M.avium_104                ALFDQQAQEEVWGEDPNVRISSSYAPMGAGVVTDG--GYLVNGSWNWSSG
MAB_0584|M.abscessus_ATCC_1997      ALFDQQAQEEVWGDDTDVRVSSSYAPMGAGVVTDAGDGYLVNGSWNWSSG
TH_4288|M.thermoresistible__bu      ASYSPQLQDEIWGGGPDTLVCSSVAPIGKSEQVAG--GIRLSGRYAWSSG
                                    * :.   *:::** .. . :.** **:* .  .    *  :.* : ****

Mflv_1463|M.gilvum_PYR-GCK          CDHATWAFLGGPVIKDGKPVDFGSFLIPRTDYRIDDVWNVVGLKATGSNT
Mvan_5308|M.vanbaalenii_PYR-1       CDHATWAFLGGPVIKDGKPVDFGSFLIPRTEYRIDDVWNVVGLKATGSNN
MSMEG_6038|M.smegmatis_MC2_155      SEHATWAFLGGPVIKDGRPVDFGSFLIPRTEYTIDDVWHVVGLRGTGSNT
Mb3601c|M.bovis_AF2122/97           CDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNT
Rv3570c|M.tuberculosis_H37Rv        CDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNT
MMAR_5065|M.marinum_M               CDHATWCFAGGPVIKDGRPVDFGSFLIPRTEYRIDDVWHVVGLRGTGSNT
MUL_4141|M.ulcerans_Agy99           CDHGTWCFAGGPVIKDGRPVDFGSFLIPRTEYRIDDVWHVVGLRGTGSNT
MAV_0591|M.avium_104                CDHATWAFLGGPVIKDGRPVDFGSFLIPRSEYRIDDVWHVVGLRGTGSNT
MAB_0584|M.abscessus_ATCC_1997      CDHATWAFLGGPVIKDGRPVDFGSFLIPRTEYRIDDVWNVVGLRGTGSNT
TH_4288|M.thermoresistible__bu      CEHAHWAMLGLLLPGIDGVPEPHLAVVPRSDYTIQDTWYSMGLKGTGSHD
                                    .:*. * : *  :   .   :    ::**::* *.*.*  :**:.***: 

Mflv_1463|M.gilvum_PYR-GCK          VVVKDVFVPRHRFLSYKAMNDGTAGGYENNTAPVYKMPWGTMHPTTISAP
Mvan_5308|M.vanbaalenii_PYR-1       VVVKDVFVPRHRFLSYKAMNDGTAGGYQNNTAPVYKMPWGTMHPTTISAP
MSMEG_6038|M.smegmatis_MC2_155      IVVKDVFVPRHRFLSYKAMNDGTAGGYATNTAPVYKMPWGTVHPTTISAP
Mb3601c|M.bovis_AF2122/97           LVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAP
Rv3570c|M.tuberculosis_H37Rv        LVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAP
MMAR_5065|M.marinum_M               VVVKDVFVPRHRFLSYKAMNDHTAGGLQTNTAPVYKMPWGTMHPTTITAP
MUL_4141|M.ulcerans_Agy99           VVVKDVFVPRHRFLSYKAMNDHTAGGLQTNTAPVYKMPWGTMHPTTITAP
MAV_0591|M.avium_104                VVVKDVFVPRHRFLSYKAMNDGTAGGYETNTAPVYKMPWGTMHPTTISAP
MAB_0584|M.abscessus_ATCC_1997      VVVKDVFVPKHRFLSYKKMNDQTAGGYQTNTAPVYKMPWGTMHPTTITAP
TH_4288|M.thermoresistible__bu      LVVEDAFVPSYRIESFSALNHGTARGFGTHAAPIYRLPFAPVFAIGFSAI
                                    :**:*.*** :*: *:. :*. ** *  .::**:*::*:..:..  ::* 

Mflv_1463|M.gilvum_PYR-GCK          IMGMAYGAYEAHVEHQGKRVRAAFAGEKSKDDPFAKIRIAEAASDIDAGW
Mvan_5308|M.vanbaalenii_PYR-1       IMGMAYGAYDAHVEHQGKRVRAAFAGEKSKDDPFAKIRIAEAASDIDAGW
MSMEG_6038|M.smegmatis_MC2_155      IVGMAYGAYAAHVEHQGKRVRAAFAGEKSKDDPFAKVRIAEAASDIDAAW
Mb3601c|M.bovis_AF2122/97           IVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAW
Rv3570c|M.tuberculosis_H37Rv        IVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAW
MMAR_5065|M.marinum_M               IVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAW
MUL_4141|M.ulcerans_Agy99           IVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAW
MAV_0591|M.avium_104                IVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAW
MAB_0584|M.abscessus_ATCC_1997      IMGMAYGAYDAHVEAQGKRVRAAYAGEKAKDDPFTKVRVAEAASDIDAGW
TH_4288|M.thermoresistible__bu      ALGAAEAMRDLYKERLASRVR-AYTGAKVAESAPALMRLAESEHELRSAY
                                     :* * .    : *  ..*** *::* *  :.. : :*:**:  :: :.:

Mflv_1463|M.gilvum_PYR-GCK          RQLIGNVRDEYELLQAGKEIPFSLRASARRDQVRATARAIASIDLLFEAS
Mvan_5308|M.vanbaalenii_PYR-1       RQLIGNVGAEYRLLEAGEEIPFSLRAAARRDQVRATARAIASIDLLFEAS
MSMEG_6038|M.smegmatis_MC2_155      RQLIGNVGEEYELLKAGKEIPFDLRARARRDQVRATGRAIASIDLLFESA
Mb3601c|M.bovis_AF2122/97           RQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEAS
Rv3570c|M.tuberculosis_H37Rv        RQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEAS
MMAR_5065|M.marinum_M               RQLMGNVGDEYALLSAGKEIPFDLRTRARRDQVRATGRSIASIDRLFEAS
MUL_4141|M.ulcerans_Agy99           RQLMGNVGDEYALLSAGKEIPFDLRTRARRDQVRATGRSIASIDRLFEAS
MAV_0591|M.avium_104                RQLSGNVADEYALLSAGKEIPFELRARARRDQVRATGRAIASIDRLFEAS
MAB_0584|M.abscessus_ATCC_1997      RQLIGNVGDEYALIAAGQEVPFELRAAARRDQVRATGRAIASIDLLFENS
TH_4288|M.thermoresistible__bu      RMLRQDWNDLDALANSGRLATADELVNWRTNQSYVTNVCVRAADRLFEAS
                                    * *  :      *  :*.  . .  .  * :*  .*  .: : * *** :

Mflv_1463|M.gilvum_PYR-GCK          GATALQLDQPVQRFWRDAHAGRVHAANEPERAYLIFGNDAFGLPPQDTMV
Mvan_5308|M.vanbaalenii_PYR-1       GATALQLDQPVQRFWRDAHAGRVHAANEPERAYLIFGNDAFGLPPQDTMV
MSMEG_6038|M.smegmatis_MC2_155      GATALINTAPLQRFWRDAHAGRVHAANEPERAYLIFGNHEFGLPPADTMV
Mb3601c|M.bovis_AF2122/97           GATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
Rv3570c|M.tuberculosis_H37Rv        GATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
MMAR_5065|M.marinum_M               GATALANDAPIQRFWRDAHAGRVHAANDPERAYVIFGNNEFGLPAGDTMV
MUL_4141|M.ulcerans_Agy99           GATALANDAPIQRFWRDAHAGRVHAANDPERAYVIFGNNEFGLPAGDTMV
MAV_0591|M.avium_104                GATALANDQPVQRFWRDAHAGRVHAANDPERAYQIFGNHEFGLPPGDTMV
MAB_0584|M.abscessus_ATCC_1997      GATALSNDAPVQRFWRDAHAGRVHAANDAERAYQIWGNHAFELPATDTMV
TH_4288|M.thermoresistible__bu      GGAAVRDENPMQRFWRDIHAGAAHAYSDYDVAAQVLGSHMAQVAVDGIF-
                                    *.:*:    *:****** *** .** .: : *  : *..   :.  . :