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TAVEQAHALRDVVGAHAAESEQLRTLAPAVVDAMWSSGLMSAFNPSAAGGSEPTFAEMIETWIEMAWQDG SFGWVGIANFPSSFAAASYLPDSGFAEVFTANDNRVTMGGQFFPNGQGVAVDGGYRLTGAWSFGSGTGHA EYVAAGFFPMVDGEMRWAGEGIPDMQVAVVPRDQVSFKDGWHVQGLRGTGSYDYAIDDVFVPHDRTFALF TREPKRGSSPAGRMGMMPVTAAGHAAWALGVAKSMLDDVAELAATKFRMSDMASLASRPTFQKDLAHHVA AWRAARLLVLDAFTGAEGAVAAGAELTPTMRADMRVAAVFATDTARGCAEWAHLAAGTTSIREGSRLERA FRDIYTGTQHAFISEKVAIDAAQVWLGVVEDQFGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3440 | - | - | 100% (386) | acyl-CoA dehydrogenase type 2 |
| M. gilvum PYR-GCK | Mflv_4548 | - | 2e-24 | 27.89% (355) | acyl-CoA dehydrogenase type 2 |
| M. gilvum PYR-GCK | Mflv_1463 | - | 4e-22 | 25.37% (406) | acyl-CoA dehydrogenase type 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 3e-37 | 33.52% (352) | hypothetical protein Mb3121c |
| M. tuberculosis H37Rv | Rv3094c | - | 3e-37 | 33.52% (352) | hypothetical protein Rv3094c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0315 | - | 3e-33 | 27.76% (371) | hypothetical protein MAB_0315 |
| M. marinum M | MMAR_3457 | - | 0.0 | 80.94% (383) | hypothetical protein MMAR_3457 |
| M. avium 104 | MAV_2767 | - | 0.0 | 80.68% (383) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0198 | - | 6e-29 | 29.11% (371) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_2929 | - | 6e-27 | 28.10% (363) | PUTATIVE acyl-CoA dehydrogenase, C- domain protein |
| M. ulcerans Agy99 | MUL_3474 | - | 3e-37 | 31.81% (371) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3194 | - | 0.0 | 87.73% (383) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3121c|M.bovis_AF2122/97 -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
Rv3094c|M.tuberculosis_H37Rv -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
MUL_3474|M.ulcerans_Agy99 MTEPPSLPGVLMNQPDLSAAPLRRADSEMEDLAEKIALTAREMSAEIDRD
Mflv_3440|M.gilvum_PYR-GCK --------------------------MTAVEQAHALRDVVGAHAAESEQL
Mvan_3194|M.vanbaalenii_PYR-1 ----------------------------MVERARGMRDLVRAQAAESEQI
MMAR_3457|M.marinum_M --------------------MISTTSGQVVALARTMRDLVRAEAGESERR
MAV_2767|M.avium_104 ------------------MTSIADTDDRVVALARGMRDLVQDQAAESERM
MAB_0315|M.abscessus_ATCC_1997 ------------------MTSSTAVQPDAVQRARELAPAIAARALEAERL
TH_2929|M.thermoresistible__bu -------------------MSATAAQTAEIT--AEFVQRLAERAAEADEL
MSMEG_0198|M.smegmatis_MC2_155 -------------------MTTQVQTHDVLDLPGALRASIEASVEEADGL
: * :
Mb3121c|M.bovis_AF2122/97 RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
Rv3094c|M.tuberculosis_H37Rv RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
MUL_3474|M.ulcerans_Agy99 RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
Mflv_3440|M.gilvum_PYR-GCK RTLAPAVVDAMWSSGLMSAFNPSAAGGSEPTFAEMIETWIEMAWQDGSFG
Mvan_3194|M.vanbaalenii_PYR-1 RTMTPAIVEAMWSTGLMSAFNPAPAGGVEPSFAEMIETWIEMAWQDGSFG
MMAR_3457|M.marinum_M RTLTDKIVNEMWSTGLMSAFNPTAAGGTEPAFAEMIETWIEMAWQDGSFG
MAV_2767|M.avium_104 RTLTPAIVDAMWASGLMSAFNTIEAGGVEPSFTEMIETWIEMAWQDGSFG
MAB_0315|M.abscessus_ATCC_1997 RRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGSTA
TH_2929|M.thermoresistible__bu RRLPAATIDDLTASGFTELLVPARYGGRQAEFPALLDPVRRMAHGCTSSA
MSMEG_0198|M.smegmatis_MC2_155 GDIPSRLHDELRDAGAFRLLTPRELGGWAAPLPTALSVYEKFGRIDGSVG
:. : :* . . : .. * .
Mb3121c|M.bovis_AF2122/97 WCVSIAITSALLVA-YLPARSREEMFGG----GRGVAAGVWAPRGTARSV
Rv3094c|M.tuberculosis_H37Rv WCVSIAITSALLVA-YLPARSREEMFGG----GRGVAAGVWAPRGTARSV
MUL_3474|M.ulcerans_Agy99 WCVSIAITSALLVA-YLPASSRDEMFGA----GRSVAAGVWAPRGKAKSV
Mflv_3440|M.gilvum_PYR-GCK WVGIANFPSSFAAASYLPDSGFAEVFTAN--DNRVTMGGQFFPNGQGVAV
Mvan_3194|M.vanbaalenii_PYR-1 WVGIANLPSSFAAATYLPDGGFAEVFTAN--HNRVTMGGQFFPNGQGHAV
MMAR_3457|M.marinum_M WIGIANLPSTFAAATYLPDDGFAEVFSAA--DNRVTMGGQFFPNGQGSAV
MAV_2767|M.avium_104 WVGIANLPSSFAAAAYLPDDGFAEVFTAH--DNHVTMGGQFFPNGQGAAV
MAB_0315|M.abscessus_ATCC_1997 WTFCIYGIHNWLAG-LFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPV
TH_2929|M.thermoresistible__bu WTIGFFALHNWMLA-LFDEQAQQEVF----ADRPVLAPAPLAPTGRGLPV
MSMEG_0198|M.smegmatis_MC2_155 LLVWNTNFG--FIGAMLPETGNKRIWGTG---VEPVFANSGMP-GTATPT
. : .:: * * . ..
Mb3121c|M.bovis_AF2122/97 DGGVVVSGRWPFCSGINHADIMFAGCFVDDR----------QVPSVVALN
Rv3094c|M.tuberculosis_H37Rv DGGVVVSGRWPFCSGINHADIMFAGCFVDDR----------QVPSVVALN
MUL_3474|M.ulcerans_Agy99 DGGVVVSGRWPFCSGINHADMMFAGCFVEGQ----------PVPSVVALP
Mflv_3440|M.gilvum_PYR-GCK DGGYRLTGAWSFGSGTGHAEYVAAGFFPMVDGEMRWAGEGIPDMQVAVVP
Mvan_3194|M.vanbaalenii_PYR-1 DGGYRLTGSWSFGSGTGHAEYVAAGFLPMVDGEIRWAGDGVPDMQVAVVP
MMAR_3457|M.marinum_M DGGYRLSGSWSFGSGTGHAQYIAAGFFPMDDGDMRWVREGVPDMQVAVVP
MAV_2767|M.avium_104 DGGYLVSGAWNFGSGIGHSQYVAAGFLPMDDGEMRWISEGFPEMRVAVIP
MAB_0315|M.abscessus_ATCC_1997 EGGYKITGRWQFGSGVWHSSWASVAAVVQHEEP-----PKYPDLRTFMIP
TH_2929|M.thermoresistible__bu DGGVRLTGRWSWATGVMHANWVLVGALCGPED------AIYPALA--LLP
MSMEG_0198|M.smegmatis_MC2_155 NGGFQLSGHWKIVTGIRSATWIVVVGIVTGDTN------GAPDVRLFAVP
:** ::* * :* : . . :
Mb3121c|M.bovis_AF2122/97 KDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDG--------P
Rv3094c|M.tuberculosis_H37Rv KDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDG--------P
MUL_3474|M.ulcerans_Agy99 KDDLRALDTWHTLGLCGTGSHDCVAEEVFVPADRVFSVFDG--------P
Mflv_3440|M.gilvum_PYR-GCK RDQVSFKDGWHVQGLRGTGSYDYAIDDVFVPHDRTFALFTRE------PK
Mvan_3194|M.vanbaalenii_PYR-1 RAEVSFKDGWHVQGLKGTGSYDYSIDDVFVPHDRTFALFTRE------PR
MMAR_3457|M.marinum_M REQITFNDGWFVQGLKGTGSYDYSAEDVFVPQGRTFGLFARE------PR
MAV_2767|M.avium_104 REQISFDDGWYVQGLKGTGSYDYSARDVFVPAARTFELFTRA------PF
MAB_0315|M.abscessus_ATCC_1997 RSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAE
TH_2929|M.thermoresistible__bu AADVTVEDTWHTVGMRATGSADVVVTEAFVPEHRLLRVTDIYAGTTPGAA
MSMEG_0198|M.smegmatis_MC2_155 TDQIDIQDTWNVTGLRATGSRDVVIDDVFVPEDLATRLDAPVN-------
:: * * . *: .*** * :.*** .
Mb3121c|M.bovis_AF2122/97 IVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTL
Rv3094c|M.tuberculosis_H37Rv IVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTL
MUL_3474|M.ulcerans_Agy99 TIDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKRTL
Mflv_3440|M.gilvum_PYR-GCK RGSSPAGRMGMMPVTAAGHAAWALGVAKSMLDDVAELAATKFRMSDMASL
Mvan_3194|M.vanbaalenii_PYR-1 RGSSPATRMGMMPVTAAGHAAWALGVAKSMLDDVSELAATKFRMSDMAAL
MMAR_3457|M.marinum_M RGSSPATRMGLMPVTAAGHASWALGVAKSMLDDVTELAATKYRMSDMAAL
MAV_2767|M.avium_104 RGASPATRMGLMPVTAAGHASWALGVAKSMLDDVQELAATKFRMSDMASL
MAB_0315|M.abscessus_ATCC_1997 LHGSAIYRIPLFCALSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQ
TH_2929|M.thermoresistible__bu LHDAAAYRWPMVPALALLAAMPALGSAERVTDLFAERLGHRVIAYEGVAQ
MSMEG_0198|M.smegmatis_MC2_155 -TDSPVYRGFIGNLVFGGCAAVTLGIAAHMIEETVTLVRSKASVVGG-VV
. * : . ::* * : :
Mb3121c|M.bovis_AF2122/97 AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPV-------
Rv3094c|M.tuberculosis_H37Rv AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAEAVPV-------
MUL_3474|M.ulcerans_Agy99 AERSATQTAVATAEAALGAARALFYEAIDSAWQASHNPDPVPVPVPVPVP
Mflv_3440|M.gilvum_PYR-GCK ASRPTFQKDLAHHVAAWRAARLLVLDAFTGAEGAVAAGAELTP-------
Mvan_3194|M.vanbaalenii_PYR-1 ASRPTFQKGLAHHVAAWRAARLLVLDAFGTAEAAVAGGDDLTP-------
MMAR_3457|M.marinum_M ASRPTFQKGLAHHVAAWRAARLLVLDAFTTAEAAVGAGQELTP-------
MAV_2767|M.avium_104 ASRPTFQKGLAHHRAAWRAARLLVLDAFTTAEAAVAAGQELTP-------
MAB_0315|M.abscessus_ATCC_1997 SKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTT-------
TH_2929|M.thermoresistible__bu RDKPIAQAHLGRARVRLRALHGLLADTVGQIQQLVAAGDPVPR-------
MSMEG_0198|M.smegmatis_MC2_155 ADATRTQYLVAKAQASVDAARLLLLSTAS---ELADAGDQLTL-------
. . : . : : *. .. :.
Mb3121c|M.bovis_AF2122/97 ---TMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
Rv3094c|M.tuberculosis_H37Rv ---TMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
MUL_3474|M.ulcerans_Agy99 VPVALRNRLRLAATHAARTSADVVRTMYDLAGSSAIYDGSPLQRRFRDAF
Mflv_3440|M.gilvum_PYR-GCK ---TMRADMRVAAVFATDTARGCAEWAHLAAGTTSIREGSRLERAFRDIY
Mvan_3194|M.vanbaalenii_PYR-1 ---TLRADMRVAAVFATDTARACAEWAHLVAGTSSIREGSRLERAFRDVY
MMAR_3457|M.marinum_M ---TLRSDMRAAAVFATDTARSCAEWAHLVAGTSSIREGSRLERAFRDMY
MAV_2767|M.avium_104 ---ALRADMRVAAVYATDTARGCAEWAHLVAGTSSIREGSRLERAFRDIY
MAB_0315|M.abscessus_ATCC_1997 ---GDRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVN
TH_2929|M.thermoresistible__bu ---PVRADARLAAAHIVHESRAIIGDLLAASGASVQFLSHPMQRFQRDVD
MSMEG_0198|M.smegmatis_MC2_155 ---DQRAAHRAAITHAAEVSRIALVDMYNLAGSSALYRTNTIERIFRDGM
* * .. . . .* : ::* **
Mb3121c|M.bovis_AF2122/97 TATAHFQVN-EASRELPGRVLLDQPADVSML-
Rv3094c|M.tuberculosis_H37Rv TATAHFQVN-EASRELPGRVLLDQPADVSML-
MUL_3474|M.ulcerans_Agy99 TATAHFQVN-EASRELPGRVLLGQHCDTSML-
Mflv_3440|M.gilvum_PYR-GCK TGTQHAFIS-EKVAIDAAQVWLGVVEDQFGL-
Mvan_3194|M.vanbaalenii_PYR-1 TGTQHAFIS-EKVAIDAAQVWLGVVEDQFGL-
MMAR_3457|M.marinum_M TGTQHAFIS-EKVAIDCAQIWLGIVEDQFGL-
MAV_2767|M.avium_104 TGTQHAFIS-EKVAIDVAQIWLGIIEDQPGL-
MAB_0315|M.abscessus_ATCC_1997 TLSTHVVYDTDSAYELYGRVELGLPPGSVAF-
TH_2929|M.thermoresistible__bu VLAGHVVFDYDTSRELAGALELGLKVSPLAMI
MSMEG_0198|M.smegmatis_MC2_155 AATQHANQS-ALFMEGAGRVRLGMDHGLPLF-
. : * . . : *. . :