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SAVQPFSEKLSAKLNDMREVLRPAERLRQQAHALGGHLGKGDSVLDVGCGTGYLSAYLQQMYGISPSGID VKDARRTEIPFREFNGTSIPFPDRSFDHVVLSEVLHHSHDPVALIKQCYRVARRSIIVFEDMPDGRLGKG ILFLHVHAFARYYRYPFRPATIGSYRSALNWLGDNASCVLQTRQPPEWLSAYPRELFVYELAESAQW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3363 | - | - | 100% (208) | hypothetical protein MMAR_3363 |
| M. marinum M | MMAR_0694 | - | 2e-10 | 30.20% (149) | hypothetical protein MMAR_0694 |
| M. marinum M | MMAR_1683 | - | 1e-05 | 26.73% (101) | hypothetical protein MMAR_1683 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1550 | - | 5e-06 | 32.26% (93) | methyltransferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1523 | - | 5e-06 | 32.26% (93) | methyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4103c | - | 4e-06 | 37.65% (85) | methyltransferase |
| M. avium 104 | MAV_0854 | - | 4e-08 | 34.92% (126) | methyltransferase-UbiE family protein |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 5e-07 | 28.85% (104) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2193 | - | 2e-05 | 32.26% (93) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1280 | - | 1e-120 | 98.08% (208) | hypothetical protein MUL_1280 |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 4e-10 | 34.96% (123) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3363|M.marinum_M --------------------------------------------------
MUL_1280|M.ulcerans_Agy99 --------------------------------------------------
Mb1550|M.bovis_AF2122/97 MTITALTVTLPLLWRRLTTAGVKYADQGHFVGSAGVPAADAGGRDAASEQ
Rv1523|M.tuberculosis_H37Rv MTITALTVTLPLLWRRLTTAGVKYADQGHFVGSAGVPAADAGGRDAASEQ
MAB_4103c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
TH_2193|M.thermoresistible__bu --------------------------------------------------
MAV_0854|M.avium_104 --------------------------------------------------
Mvan_4620|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3363|M.marinum_M -------------------------------------------------M
MUL_1280|M.ulcerans_Agy99 -------------------------------------------------M
Mb1550|M.bovis_AF2122/97 IARWTQTCTVVLVCGHGPAKWAFRSWCTSRSCDTLPVALRYRLQSNPLVG
Rv1523|M.tuberculosis_H37Rv IARWTQTCTVVLVCGHGPAKWAFRSWCTSRSCDTLPVALRYRLQSNPLVG
MAB_4103c|M.abscessus_ATCC_199 ---------------------------MQRSRD------WVMFKLNAVFT
MSMEG_2350|M.smegmatis_MC2_155 ---------------------------------------------MGDPD
TH_2193|M.thermoresistible__bu ---------------------------------------MSAFSTAGSDA
MAV_0854|M.avium_104 -----------------------------------------------MND
Mvan_4620|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3363|M.marinum_M SAVQPFSEKLSAKLNDMREVLRPAERLRQQAHALGGHLGK----------
MUL_1280|M.ulcerans_Agy99 SAVQPFSEKLSAKLNDMREVLRPAERLRQQAHALGGHLGK----------
Mb1550|M.bovis_AF2122/97 KLTTKYFLPLGTRQVG-DHVVFFNFGYEEDPPMALPLSESDEPNRYCIQL
Rv1523|M.tuberculosis_H37Rv KLTTKYFLPLGTRQVG-DHVVFFNFGYEEDPPMALPLSESDEPNRYCIQL
MAB_4103c|M.abscessus_ATCC_199 QRVQKFIYRHATRKLETEDVVFLNYGYEEEPAMGVPLSASDEPDRYSIQL
MSMEG_2350|M.smegmatis_MC2_155 NALPSALPLTGERTIP--GLAEENYWFRRHEVVYQRLAHR----------
TH_2193|M.thermoresistible__bu DGPISVLPLTGERTVP--GLERENYWFRRHEVVYQRLAHR----------
MAV_0854|M.avium_104 QHRATYTHGHHESVLR----SHRRRTAEDSAGYLLAHLTP----------
Mvan_4620|M.vanbaalenii_PYR-1 -----MSFVVASEAYG----RFMGRYAEPLAEAFVAFAGVG---------
.
MMAR_3363|M.marinum_M -----------GDSVLDVGCGTGYLSAYLQQMYG--------ISPSGIDV
MUL_1280|M.ulcerans_Agy99 -----------GDSVLDVGCGTGYLSAYLQQMYG--------ISPSGIDV
Mb1550|M.bovis_AF2122/97 YHQTASQVDLTGKEVLEVSCGAGGGASYIARNLGPASYTGLDLNPASIDL
Rv1523|M.tuberculosis_H37Rv YHQTASQVDLTGKEVLEVSCGAGGGASYIARNLGPASYTGLDLNPASIDL
MAB_4103c|M.abscessus_ATCC_199 YHSTATQADLGGQRVLEVGCGHGGGASYLVRALQPASYTGLDLNPDGISF
MSMEG_2350|M.smegmatis_MC2_155 ---------CAGRDVLEAGCGEGYGADLIADVAR--RVIGLDYDEATVAH
TH_2193|M.thermoresistible__bu ---------CAGRVVLEAGCGEGYGADLLAEVAA--HVIGLDYDAATVAH
MAV_0854|M.avium_104 -----------GLSVLDVGCGPGTITADLAARVAPGQVTAVDQAADVLEV
Mvan_4620|M.vanbaalenii_PYR-1 ----------VGDKVLDVGCGPGALTARLRSVGA--DIAAIDPSPPFIDA
* **:..** * : : :
MMAR_3363|M.marinum_M KDARR-----TEIPFREFNGTSIPFPDRSFDHVVLSEVLHHSHDPVALIK
MUL_1280|M.ulcerans_Agy99 KDVRR-----TEIPFREFNGTSIPFPDRSFDHVVLSEVLHHSHDPVALIK
Mb1550|M.bovis_AF2122/97 CRAKHR---LPGLQFVQGDAQNLPFPDESFDAVVNVEASHQYPDFRGFLA
Rv1523|M.tuberculosis_H37Rv CRAKHR---LPGLQFVQGDAQNLPFPDESFDAVVNVEASHQYPDFRGFLA
MAB_4103c|M.abscessus_ATCC_199 CRRRHD---LPGLEFVQGDAEDLPFPDESFDAVINVESSHLYPHFPVFLT
MSMEG_2350|M.smegmatis_MC2_155 VRARY-----PRVDIRHGNLAELPLPDASVDVVVNFQVIEHLWDQAQFVS
TH_2193|M.thermoresistible__bu VRARY-----PRVDIRHGNLVDLPLADASVDVVVNFQVIEHLWDQEKFIA
MAV_0854|M.avium_104 ARAEAEQRNLSNVSFGTADVHRLDFADDTFDVVHAHQVLQHLSDPVAALR
Mvan_4620|M.vanbaalenii_PYR-1 IRRSFP-----DVDVRQGPAEELPYDSAAFDAALAQLVVHFMTDPVAGLR
: . : . :.* . . . :
MMAR_3363|M.marinum_M QCYRVARRSIIVFEDMPDG---RLGKGILFLHVH--AFARYYRYPFRPAT
MUL_1280|M.ulcerans_Agy99 QCYRVARRSIIVFEDMPDG---RLGKGILFLHVH--VFARYYRYPFRPAT
Mb1550|M.bovis_AF2122/97 EVARVLRPGGHFLYTDSRRNPVVAEWEAALADAP--LRTISQRDIGAQAK
Rv1523|M.tuberculosis_H37Rv EVARVLRPGGHFLYTDSRRNPVVAEWEAALADAP--LRTISQRDIGAQAK
MAB_4103c|M.abscessus_ATCC_199 EVARVLRPGGNFLYTDARSVQDVAGWKVALANAP--LRMVSERGINAEVR
MSMEG_2350|M.smegmatis_MC2_155 ECFRVLRPGGVFLVSTPNRITFSPGRDTPLNPFH--TRELNAAELTELLE
TH_2193|M.thermoresistible__bu ECLRVLRPGGQLLVSTPNRITFTPGSDTPVNPFH--TRELNAAELTELLT
MAV_0854|M.avium_104 EMRRVCRPGGIVAVRDADYAGFIWYPELPALDLWRDLYRRVARANRGEPD
Mvan_4620|M.vanbaalenii_PYR-1 QMSRVTRPGGVVAACVWDGPTGALAPFWDAVHVVD--PEAEDEALLSGAR
: ** * . .
MMAR_3363|M.marinum_M IG------------------------SYRSALNWLGDNASCVLQT-----
MUL_1280|M.ulcerans_Agy99 IG------------------------SYRSALNWLGDNASCVLQA-----
Mb1550|M.bovis_AF2122/97 RG---------------------LDANTARSQEAIGRRAPVLLAG-----
Rv1523|M.tuberculosis_H37Rv RG---------------------LDANTARSQEAIGRRAPVLLAG-----
MAB_4103c|M.abscessus_ATCC_199 RG---------------------MEKNLARWRYVIDRATPAPLRG-----
MSMEG_2350|M.smegmatis_MC2_155 TAGFEVEDTLGV-----FHGAGLAELDARHGGSIIEAQVQRAVADAPWDE
TH_2193|M.thermoresistible__bu DGGFGLSAMYGV-----FHGPRLAELDARHGGSIIDAQISRALADEPWPA
MAV_0854|M.avium_104 AGRRLLSWARQAGFDDITPTGSLWCYATPETRDWWGGMWADRILHSTVAR
Mvan_4620|M.vanbaalenii_PYR-1 SG------------------HLTELFEAAGLRDVVEDSIAVDVVHPTFEQ
. :
MMAR_3363|M.marinum_M -------RQPPE-------WLSAYPR------------ELFVYELAESAQ
MUL_1280|M.ulcerans_Agy99 -------RQPPE-------WLSVYPR------------ELFVYELAESAQ
Mb1550|M.bovis_AF2122/97 -LTR--CAVRVL-------DWDLRRG---------GGFSYRIYLFAKD--
Rv1523|M.tuberculosis_H37Rv -LTR--CAVRVL-------DWDLRRG---------GGFSYRIYLFAKD--
MAB_4103c|M.abscessus_ATCC_199 -IVRRFAPAQRA-------YDDLRAG---------GSVEYRMYRFVKA--
MSMEG_2350|M.smegmatis_MC2_155 QLLADVAAVRTD-------DFDLTPAAERD-------IDDSLDLVAIAVR
TH_2193|M.thermoresistible__bu ELLADVASVRTE-------DFDLIRCDEDDRDRDGHNIDDSLDLVAIAVR
MAV_0854|M.avium_104 DLVSLGLAAREQ-------LEEISAAWREWAAAPDGWIAIPHGEIICRA-
Mvan_4620|M.vanbaalenii_PYR-1 WWEPYTYGVGPAGDYVQQLDDEGRARLESAARERLGKGPFTVTAVAWAAR
. .
MMAR_3363|M.marinum_M W--
MUL_1280|M.ulcerans_Agy99 W--
Mb1550|M.bovis_AF2122/97 ---
Rv1523|M.tuberculosis_H37Rv ---
MAB_4103c|M.abscessus_ATCC_199 ---
MSMEG_2350|M.smegmatis_MC2_155 P--
TH_2193|M.thermoresistible__bu P--
MAV_0854|M.avium_104 ---
Mvan_4620|M.vanbaalenii_PYR-1 GTA