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MSAVQPFSEKLSAKLNDMREVLRPAERLRQQAHALGGHLGKGDSVLDVGCGTGYLSAYLQQMYGISPSGI DVKDVRRTEIPFREFNGTSIPFPDRSFDHVVLSEVLHHSHDPVALIKQCYRVARRSIIVFEDMPDGRLGK GILFLHVHVFARYYRYPFRPATIGSYRSALNWLGDNASCVLQARQPPEWLSVYPRELFVYELAESAQW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1280 | - | - | 100% (208) | hypothetical protein MUL_1280 |
| M. ulcerans Agy99 | MUL_1921 | - | 3e-06 | 27.72% (101) | hypothetical protein MUL_1921 |
| M. ulcerans Agy99 | MUL_0368 | - | 7e-05 | 29.70% (101) | hypothetical protein MUL_0368 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3056 | - | 2e-06 | 28.87% (97) | hypothetical protein Mb3056 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3030 | - | 2e-06 | 28.87% (97) | hypothetical protein Rv3030 |
| M. leprae Br4923 | MLBr_01723 | - | 8e-05 | 31.25% (96) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_4103c | - | 7e-06 | 37.65% (85) | methyltransferase |
| M. marinum M | MMAR_3363 | - | 1e-119 | 98.08% (208) | hypothetical protein MMAR_3363 |
| M. avium 104 | MAV_0854 | - | 2e-08 | 35.71% (126) | methyltransferase-UbiE family protein |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 4e-07 | 28.85% (104) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2193 | - | 1e-05 | 32.26% (93) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 2e-10 | 34.96% (123) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1280|M.ulcerans_Agy99 -------------------------------MSAVQPFSEKLSAKLNDMR
MMAR_3363|M.marinum_M -------------------------------MSAVQPFSEKLSAKLNDMR
Mb3056|M.bovis_AF2122/97 -----------MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDL
Rv3030|M.tuberculosis_H37Rv -----------MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDL
MSMEG_2350|M.smegmatis_MC2_155 -----------------------MGDP----DNALPSALPLTGERTIPGL
TH_2193|M.thermoresistible__bu -----------MSAFS------TAGSD----ADGPISVLPLTGERTVPGL
MAV_0854|M.avium_104 ---------------------------------MNDQHRATYTHGHHESV
Mvan_4620|M.vanbaalenii_PYR-1 ---------------------------------------MSFVVASEAYG
MLBr_01723|M.leprae_Br4923 ---MTRSTEISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEK
MAB_4103c|M.abscessus_ATCC_199 MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEEEPAM
MUL_1280|M.ulcerans_Agy99 EVLRPAERLRQQAHALGGHLG--------KGDSVLDVGCGTGY----LSA
MMAR_3363|M.marinum_M EVLRPAERLRQQAHALGGHLG--------KGDSVLDVGCGTGY----LSA
Mb3056|M.bovis_AF2122/97 DIENYWFRRHQVVYQRLAPRC--------TARDVLEAGCGEGYGADLIAC
Rv3030|M.tuberculosis_H37Rv DIENYWFRRHQVVYQRLAPRC--------TARDVLEAGCGEGYGADLIAC
MSMEG_2350|M.smegmatis_MC2_155 AEENYWFRRHEVVYQRLAHRC--------AGRDVLEAGCGEGYGADLIAD
TH_2193|M.thermoresistible__bu ERENYWFRRHEVVYQRLAHRC--------AGRVVLEAGCGEGYGADLLAE
MAV_0854|M.avium_104 LRSHRRRTAEDSAGYLLAHLT--------PGLSVLDVGCGPGTITADLAA
Mvan_4620|M.vanbaalenii_PYR-1 RFMGRYAEPLAEAFVAFAGVG--------VGDKVLDVGCGPGALTARLRS
MLBr_01723|M.leprae_Br4923 WSISYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQ
MAB_4103c|M.abscessus_ATCC_199 GVPLSASDEPDRYSIQLYHSTAT--QADLGGQRVLEVGCGHGGGASYLVR
.*: *** * :
MUL_1280|M.ulcerans_Agy99 YLQ--QMYGISPSGIDVKDVRR-------TEIPFREFNGTSIPFPDRSFD
MMAR_3363|M.marinum_M YLQ--QMYGISPSGIDVKDARR-------TEIPFREFNGTSIPFPDRSFD
Mb3056|M.bovis_AF2122/97 VAR--QVIAVDYDETAVAHVRSRY-----PRVEVMQANLAELPLPDASVD
Rv3030|M.tuberculosis_H37Rv VAR--QVIAVDYDETAVAHVRSRY-----PRVEVMQANLAELPLPDASVD
MSMEG_2350|M.smegmatis_MC2_155 VAR--RVIGLDYDEATVAHVRARY-----PRVDIRHGNLAELPLPDASVD
TH_2193|M.thermoresistible__bu VAA--HVIGLDYDAATVAHVRARY-----PRVDIRHGNLVDLPLADASVD
MAV_0854|M.avium_104 RVAPGQVTAVDQAADVLEVARAEAEQRNLSNVSFGTADVHRLDFADDTFD
Mvan_4620|M.vanbaalenii_PYR-1 VGA--DIAAIDPSPPFIDAIRRSF-----PDVDVRQGPAEELPYDSAAFD
MLBr_01723|M.leprae_Br4923 SGVARRGSVTDLSPGMVKIATRNGQSLG-LDINGRVADAEGIPYDDNTFD
MAB_4103c|M.abscessus_ATCC_199 ALQPASYTGLDLNPDGISFCRRRHD---LPGLEFVQGDAEDLPFPDESFD
. : : : . :.*
MUL_1280|M.ulcerans_Agy99 HVVLSEVLHHSHDPVALIKQCYRVARRSI-IVFEDMPD------------
MMAR_3363|M.marinum_M HVVLSEVLHHSHDPVALIKQCYRVARRSI-IVFEDMPD------------
Mb3056|M.bovis_AF2122/97 VVVNFQVIEHLWDQARFVRECARVLRGSG-LLMVSTPNRITFSPGRDTPI
Rv3030|M.tuberculosis_H37Rv VVVNFQVIEHLWDQARFVRECARVLRGSG-LLMVSTPNRITFSPGRDTPI
MSMEG_2350|M.smegmatis_MC2_155 VVVNFQVIEHLWDQAQFVSECFRVLRPGG-VFLVSTPNRITFSPGRDTPL
TH_2193|M.thermoresistible__bu VVVNFQVIEHLWDQEKFIAECLRVLRPGG-QLLVSTPNRITFTPGSDTPV
MAV_0854|M.avium_104 VVHAHQVLQHLSDPVAALREMRRVCRPGG-IVAVRDADYAGFIWYPELPA
Mvan_4620|M.vanbaalenii_PYR-1 AALAQLVVHFMTDPVAGLRQMSRVTRPGG-VVAACVWDGPTGALAPFWDA
MLBr_01723|M.leprae_Br4923 LVVGHAVLHHIPDVELSLREVLRVLKPGGRFVFAGEPTDVGNRYARVFAD
MAB_4103c|M.abscessus_ATCC_199 AVINVESSHLYPHFPVFLTEVARVLRPGGNFLYTDARSVQDVAG------
. . . : : ** : . .
MUL_1280|M.ulcerans_Agy99 ----GRLGK------------GILFLHVHVFARYYRYPFRPATIGSYRSA
MMAR_3363|M.marinum_M ----GRLGK------------GILFLHVHAFARYYRYPFRPATIGSYRSA
Mb3056|M.bovis_AF2122/97 NPFHTRELN------------ADELTSLLIDAGFVDVAMCGLFHGPRLRD
Rv3030|M.tuberculosis_H37Rv NPFHTRELN------------ADELTSLLIDAGFVDVAMCGLFHGPRLRD
MSMEG_2350|M.smegmatis_MC2_155 NPFHTRELN------------AAELTELLETAGFEVEDTLGVFHGAGLAE
TH_2193|M.thermoresistible__bu NPFHTRELN------------AAELTELLTDGGFGLSAMYGVFHGPRLAE
MAV_0854|M.avium_104 LDLWRDLYRRVARANRGEPDAGRRLLSWARQAGFDDITPTGSLWCYATPE
Mvan_4620|M.vanbaalenii_PYR-1 VHVVDPEAEDEALLSG---ARSGHLTELFEAAGLRDVVEDSIAVDVVHPT
MLBr_01723|M.leprae_Br4923 LTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEPKVLET
MAB_4103c|M.abscessus_ATCC_199 --------------------WKVALANAPLRMVSERGINAEVRRGMEKNL
:
MUL_1280|M.ulcerans_Agy99 LNWLGDN---ASCVLQARQ-PPEWLSVYPRELFVYELAESAQW-------
MMAR_3363|M.marinum_M LNWLGDN---ASCVLQTRQ-PPEWLSAYPRELFVYELAESAQW-------
Mb3056|M.bovis_AF2122/97 MDARHGGSIIDAQIMRAVA-GAPWPPELAADVAAVTTADFEMVAAGHDR-
Rv3030|M.tuberculosis_H37Rv MDARHGGSIIDAQIMRAVA-GAPWPPELAADVAAVTTADFEMVAAGHDR-
MSMEG_2350|M.smegmatis_MC2_155 LDARHGGSIIEAQVQRAVA-DAPWDEQLLADVAAVRTDDFDLTPAAERD-
TH_2193|M.thermoresistible__bu LDARHGGSIIDAQISRALA-DEPWPAELLADVASVRTEDFDLIRCDEDDR
MAV_0854|M.avium_104 TRDWWGGMWADRILHSTVARDLVSLGLAAREQLEEISAAWREWAAAPDG-
Mvan_4620|M.vanbaalenii_PYR-1 FEQWWEPYTYGVGPAGDYVQQLDDEGRARLESAARERLGKGPFTVTAVA-
MLBr_01723|M.leprae_Br4923 MATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWARFAFTS-
MAB_4103c|M.abscessus_ATCC_199 ARWRYVIDRATPAPLRGIVRRFAPAQRAYDDLRAGGSVEYRMYRFVKA--
.
MUL_1280|M.ulcerans_Agy99 ---------------------------------------
MMAR_3363|M.marinum_M ---------------------------------------
Mb3056|M.bovis_AF2122/97 -----DIDDSLDLIAIAVRP-------------------
Rv3030|M.tuberculosis_H37Rv -----DIDDSLDLIAIAVRP-------------------
MSMEG_2350|M.smegmatis_MC2_155 ------IDDSLDLVAIAVRP-------------------
TH_2193|M.thermoresistible__bu DRDGHNIDDSLDLVAIAVRP-------------------
MAV_0854|M.avium_104 -------WIAIPHGEIICRA-------------------
Mvan_4620|M.vanbaalenii_PYR-1 -------WAARGTA-------------------------
MLBr_01723|M.leprae_Br4923 -------WKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
MAB_4103c|M.abscessus_ATCC_199 ---------------------------------------