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LSVEARTPVAVGVGEVTHRGDDVVTGLGWYSTKHSVGVWSATPPPTGWRLIDTADEQTPIDSSRLAVAGV DEATGRATVDGYTVEYDRDGRPRWTPTIAHLSDGRRVVARSDDPQIAEAMAGEMYVGRTVCLRNTGSSTG FELP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3162 | - | - | 100% (144) | hypothetical protein MMAR_3162 |
| M. marinum M | MMAR_2746 | - | 2e-08 | 29.66% (118) | hypothetical protein MMAR_2746 |
| M. marinum M | MMAR_4547 | - | 2e-06 | 30.84% (107) | thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1898 | - | 9e-09 | 30.51% (118) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_4625 | - | 2e-36 | 55.37% (121) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv1867 | - | 9e-09 | 30.51% (118) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2042c | - | 2e-61 | 88.52% (122) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_2851 | - | 4e-09 | 34.48% (116) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_3608 | - | 4e-09 | 32.28% (127) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_1434 | - | 3e-10 | 30.77% (117) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3008 | - | 3e-08 | 28.81% (118) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3068 | - | 6e-08 | 31.62% (117) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1898|M.bovis_AF2122/97 --MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADSTVL
Rv1867|M.tuberculosis_H37Rv --MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADSTVL
MUL_3008|M.ulcerans_Agy99 --MAVDPRTPVLIGYGQVNYRDEIDPTMPSVEPVDLMLAAAQQAADSRVL
MAV_2851|M.avium_104 --MTVDPRTPVLIGYGQVNHRDDIDPAVRSVEPVDLMAAAVERAADAAVI
MSMEG_3608|M.smegmatis_MC2_155 ----MN-RTPVLVGYGQVSQYDENPA----TEPVDLMAEAARNAADPRVL
Mvan_3068|M.vanbaalenii_PYR-1 --MPIDPRTPVLVGYGQVNQHDENPD----VEPVDLMVQAARAAADPRLL
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_3162|M.marinum_M --MSVEARTPVAVGVGEVTHRGDD--------------------------
MAB_2042c|M.abscessus_ATCC_199 MPMLVEARTPVVVGVGEVTHRGNDFVD--PIDLAVEAARRAVKDAGRPVE
Mflv_4625|M.gilvum_PYR-GCK ----MIPRDNPASRIAEATGLTPDHR------------------------
Mb1898|M.bovis_AF2122/97 EAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSLVNR
Rv1867|M.tuberculosis_H37Rv EAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSLVNR
MUL_3008|M.ulcerans_Agy99 AAVDSMRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQPLVSQ
MAV_2851|M.avium_104 EAVDSIRVVNILSAQYRDPGLLLGQRIGARDFGTLYTPVGGNVPQSLVNQ
MSMEG_3608|M.smegmatis_MC2_155 QAVDSVRVVNLLSWRYRDPGLLLAGRIGAAGARTRYTGIGGNVPQTLVNH
Mvan_3068|M.vanbaalenii_PYR-1 EAVDAVRVVNLLSWRYRDPGLLLAQRIRADKAVTRYTGIGGNVPQTLVNM
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 RRIDTVATPGILVIPRDNPASRIAEAMHISPARRISCPVGGNTPQYLVEV
Mflv_4625|M.gilvum_PYR-GCK ----------------------------------ISCPVGGNTPQYLVEV
Mb1898|M.bovis_AF2122/97 ACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPDMAG
Rv1867|M.tuberculosis_H37Rv ACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPDMAG
MUL_3008|M.ulcerans_Agy99 ACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPRVAG
MAV_2851|M.avium_104 ACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSVPMAEVSG
MSMEG_3608|M.smegmatis_MC2_155 ACLDLQAGRAEVVLIAGAETWRTRSRLRARGVRPDWTRQDDTVPVAPGGD
Mvan_3068|M.vanbaalenii_PYR-1 ACLDIQQGKADVVLIAGAETWRTRSRIRAAGRRPDWTKQDESVPSAPGGD
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 LGGEIREGRADVVLVVGAESGHSARKLQGRALLD---SPPPPRSGDESLG
Mflv_4625|M.gilvum_PYR-GCK LGRRIWRGVSDAALIVGAESGASARKVASGSALL---EPKPIAAQDESLG
Mb1898|M.bovis_AF2122/97 DDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGELWAR
Rv1867|M.tuberculosis_H37Rv DDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGELWAR
MUL_3008|M.ulcerans_Agy99 QDVPMAGESEIRIKLDRAAYVYPMFEQALRIANGESIEDHRSRVGRLWAG
MAV_2851|M.avium_104 EDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRLWAR
MSMEG_3608|M.smegmatis_MC2_155 DNVPMAGDAENRIKLDRPAFVYPMFEQALRIAAGETPDEHRDRIGALWSR
Mvan_3068|M.vanbaalenii_PYR-1 ESVPMAAPSDIRINLDRPAYVYPMFEQALRIAAGETPDEHRRRIGELWAQ
TH_1434|M.thermoresistible__bu ----MATPADIRIQLDRPSYVYPLFEQALRITAGEHPDAHRRRIGELWAR
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 DARPGLSQAELSVGLSWPHEVYPIFESAIAARHGRDFDAQREWLGTLMAP
Mflv_4625|M.gilvum_PYR-GCK DTRPGLSEAEVGAGLHWPHEVYPIFESAIAARSGRTFDEQRRWLGDLMAP
Mb1898|M.bovis_AF2122/97 FSAVAADN-PHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVDQG
Rv1867|M.tuberculosis_H37Rv FSAVAADN-PHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVDQG
MUL_3008|M.ulcerans_Agy99 FNAVAVDN-PHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVDQG
MAV_2851|M.avium_104 FNAVAVDN-PHAWIRTPHSADDICRAGPHNRMISWPYTKLMNSNNMVDQG
MSMEG_3608|M.smegmatis_MC2_155 FSAVAARN-PHAWNRDAVTAQQITQVGPDNRMISWPYPKLMNSNNMVDQG
Mvan_3068|M.vanbaalenii_PYR-1 FSAVAADN-PHAWNREALTPEQIWQPSASNRMISWPYTKLMNSNNMVDQG
TH_1434|M.thermoresistible__bu FSAVAADN-PHAWNRKALSAEQIWRPGPDNRMISWPYPKLMNSNNMVDQG
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 FTAEAARHPEQAWFPRARSATELSEVTAENRMVCLPYPKLLNSIMSVDMA
Mflv_4625|M.gilvum_PYR-GCK FTVEASRHLEQAWFPRARSADELSTVSPANRMVCEPYPKLLNSIIAVDMA
Mb1898|M.bovis_AF2122/97 AALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAIRI
Rv1867|M.tuberculosis_H37Rv AALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAIRI
MUL_3008|M.ulcerans_Agy99 AALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSSAERAELHQSPAIRI
MAV_2851|M.avium_104 AALVLTSVEQARRLKVPPERWVYPLAGTDAHDTASIAERHELHRSAAIRI
MSMEG_3608|M.smegmatis_MC2_155 AVLILTTVQMATYLQIPMDRWVFPYAGTDSHDTYAIGERDELHRSPAIRI
Mvan_3068|M.vanbaalenii_PYR-1 AVLIVASAETARHLQIPSDRWVFPYAGADSHDTYAIAERAEFHTSPAIRI
TH_1434|M.thermoresistible__bu AALILTSVQRARELRIPSERWVFPYAGTDAHDTYAIGERYRLDRSPAIRI
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 AAFILMAAEVADELGVARDRWVFPWSAATCNDVYFPVERPDLSRSSGIEV
Mflv_4625|M.gilvum_PYR-GCK AAFVIMAAEVAEELGVPSDRWVFPWSSATCNDVYFPVQRPDLGRSAGIRA
Mb1898|M.bovis_AF2122/97 AGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLTVT
Rv1867|M.tuberculosis_H37Rv AGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLTVT
MUL_3008|M.ulcerans_Agy99 AGARALELAGLGINDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLTVT
MAV_2851|M.avium_104 AGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPLTVT
MSMEG_3608|M.smegmatis_MC2_155 AGRRVLELAGADIDAIDFVDVYSCFPSAVQVAAAELGLPTDDPARPLTVT
Mvan_3068|M.vanbaalenii_PYR-1 AGRRALELAGAGVDDMDLVDVYSCFPSAVQVAARELGLPVGKPDRPLTVT
TH_1434|M.thermoresistible__bu AGRRVLELAGLGIDDFRFVDVYSCFPSAVQVAAIELGLPLDDPARPLTVT
MMAR_3162|M.marinum_M --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 AARKALNAGRLTIDDIRWFDLYSCFPSAIEMTAEALDLDPLD-DRGLTVT
Mflv_4625|M.gilvum_PYR-GCK AGKAVLAASGLHIDDIRWFDFYSCFPSAVEAAIDALDLDPAD-DRGFTVT
Mb1898|M.bovis_AF2122/97 GGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFGVY
Rv1867|M.tuberculosis_H37Rv GGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFGVY
MUL_3008|M.ulcerans_Agy99 GGLTFAGGPWDNYVTHSIATMAELLAANPGRRGLITANGGYLTQHSIGVY
MAV_2851|M.avium_104 GGLTFAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSFGVY
MSMEG_3608|M.smegmatis_MC2_155 GGLTFAGGPWNNYVTHSIATMAEKLVAEPGTRGLITANGGYLTKHSFGVY
Mvan_3068|M.vanbaalenii_PYR-1 GGLTFAGGPWNNYVTHSIATMAERLAAQPGQRGLITANGGYLTKHSFGVY
TH_1434|M.thermoresistible__bu GGLTFAGGPWNNYVTHAIATMAERLIAAPGSRGLVTANGGYLTKHAFGVY
MMAR_3162|M.marinum_M ---------------------------------VVTGLGWYSTKHSVGVW
MAB_2042c|M.abscessus_ATCC_199 GGLPYHGGPGNNYVSHSIVEMVRRCRRDPTDVGLVTGLGWYSTKHSVGLW
Mflv_4625|M.gilvum_PYR-GCK GGLPYHGGPGNNYVSHSIVEMVRRCRSDPDAVGLVSGLGWYITKHSLGLW
:::. * * *:*:.*::
Mb1898|M.bovis_AF2122/97 GTEPPS-EFRWEDMQPAVDREPTG----DGLVEWEGIGTVEAWTTPVNRD
Rv1867|M.tuberculosis_H37Rv GTEPPS-EFRWEDMQPAVDREPTG----DGLVEWEGIGTVEAWTTPVNRD
MUL_3008|M.ulcerans_Agy99 GTEPPA-EFRWEDVQPLVDREPTR----AALVGWDGVGAVEAWTTPFTRD
MAV_2851|M.avium_104 GTEPPA-EFRWEDTQSAVDREPTT----DAAVEWEGVGTVEAWTTPHDRE
MSMEG_3608|M.smegmatis_MC2_155 GTEPPEQEFRWEDVQSVVDAEPTR----KLAVEWVGTGTVESWTTPFNRD
Mvan_3068|M.vanbaalenii_PYR-1 GTEPPKHEFRWEDVQSEVDREPTR----TAVVEWSGVGTVESWTTPVDRD
TH_1434|M.thermoresistible__bu STEPPPVEFRWEDVQSEVDREPVR----KVLVEWSGTGTVESWTTPFDRD
MMAR_3162|M.marinum_M SATPPPTGWRLIDTADEQTPIDSSRLAVAGVDEATGRATVDGYTVEYDRD
MAB_2042c|M.abscessus_ATCC_199 SATPPPTGWRLLDTAVEQAQIDSSRLGVAGVDEATGCATVDGYTVVYDRD
Mflv_4625|M.gilvum_PYR-GCK SATPPPTGWQTPDMADAQSAIDGTSLPVASPADASGEATIDGYTVVHDRD
.: ** :: * * .:::.:*. *:
Mb1898|M.bovis_AF2122/97 GQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTAT
Rv1867|M.tuberculosis_H37Rv GQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTAT
MUL_3008|M.ulcerans_Agy99 GQPEKAFVAVRTPTGARTLGVITDPASAHATVHEDIAGAKVAIAADGNAT
MAV_2851|M.avium_104 GEPEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVAADGSAA
MSMEG_3608|M.smegmatis_MC2_155 GAPEKAFLAVRTPDGARTLAVITDESQAAATVREDIAGARVEVHADGTAT
Mvan_3068|M.vanbaalenii_PYR-1 GAPEKAFLAVRTPEDARVLAVITDRAGAEATVRDDIAGAAVRVHADGTAS
TH_1434|M.thermoresistible__bu GNPEKAFVAVRTPEDSRALAVIIDPSAAAVTVSEDVAGAPIRVHADGTAT
MMAR_3162|M.marinum_M GRPRWTPTIAHLSDGRRVVARSDDPQIAEAMAGEMYVGRTVCLRNTGSST
MAB_2042c|M.abscessus_ATCC_199 GQPRWTPIIAHLSDGRRVVARSDDPQIAEAMGGEMYVGKTVCLRNTGSFT
Mflv_4625|M.gilvum_PYR-GCK QGPSWVPIFARMTDGRRVAARSDDAEVAVAMSRDMCVGHQVAVRQADGHV
* . .: . . * . * . . : * : : .
Mb1898|M.bovis_AF2122/97 LR---
Rv1867|M.tuberculosis_H37Rv LR---
MUL_3008|M.ulcerans_Agy99 LR---
MAV_2851|M.avium_104 LQ---
MSMEG_3608|M.smegmatis_MC2_155 LL---
Mvan_3068|M.vanbaalenii_PYR-1 LE---
TH_1434|M.thermoresistible__bu LG---
MMAR_3162|M.marinum_M GFELP
MAB_2042c|M.abscessus_ATCC_199 GFELP
Mflv_4625|M.gilvum_PYR-GCK EFELS