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PMLVEARTPVVVGVGEVTHRGNDFVDPIDLAVEAARRAVKDAGRPVERRIDTVATPGILVIPRDNPASRI AEAMHISPARRISCPVGGNTPQYLVEVLGGEIREGRADVVLVVGAESGHSARKLQGRALLDSPPPPRSGD ESLGDARPGLSQAELSVGLSWPHEVYPIFESAIAARHGRDFDAQREWLGTLMAPFTAEAARHPEQAWFPR ARSATELSEVTAENRMVCLPYPKLLNSIMSVDMAAAFILMAAEVADELGVARDRWVFPWSAATCNDVYFP VERPDLSRSSGIEVAARKALNAGRLTIDDIRWFDLYSCFPSAIEMTAEALDLDPLDDRGLTVTGGLPYHG GPGNNYVSHSIVEMVRRCRRDPTDVGLVTGLGWYSTKHSVGLWSATPPPTGWRLLDTAVEQAQIDSSRLG VAGVDEATGCATVDGYTVVYDRDGQPRWTPIIAHLSDGRRVVARSDDPQIAEAMGGEMYVGKTVCLRNTG SFTGFELP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2042c | - | - | 100% (499) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_3826c | - | 2e-73 | 36.44% (505) | acetyl-CoA acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1898 | - | 5e-75 | 37.03% (505) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_4625 | - | 1e-179 | 69.63% (438) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv1867 | - | 5e-75 | 37.03% (505) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2746 | - | 6e-74 | 35.11% (507) | hypothetical protein MMAR_2746 |
| M. avium 104 | MAV_2851 | - | 2e-71 | 36.20% (500) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_3608 | - | 1e-75 | 37.02% (497) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_1434 | - | 2e-61 | 40.52% (343) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3008 | - | 6e-71 | 34.12% (507) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3068 | - | 9e-76 | 36.47% (499) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1898|M.bovis_AF2122/97 --MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADST--
Rv1867|M.tuberculosis_H37Rv --MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADST--
MMAR_2746|M.marinum_M --MVVDPRTPVLIGYGQVNYRDEIDPTMPSVEPVDLMLAAAQQAADSR--
MUL_3008|M.ulcerans_Agy99 --MAVDPRTPVLIGYGQVNYRDEIDPTMPSVEPVDLMLAAAQQAADSR--
MAV_2851|M.avium_104 --MTVDPRTPVLIGYGQVNHRDDIDPAVRSVEPVDLMAAAVERAADAA--
MSMEG_3608|M.smegmatis_MC2_155 ----MN-RTPVLVGYGQVSQYDEN----PATEPVDLMAEAARNAADPR--
Mvan_3068|M.vanbaalenii_PYR-1 --MPIDPRTPVLVGYGQVNQHDEN----PDVEPVDLMVQAARAAADPR--
TH_1434|M.thermoresistible__bu --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 MPMLVEARTPVVVGVGEVTHRGND-----FVDPIDLAVEAARRAVKDAGR
Mflv_4625|M.gilvum_PYR-GCK --------------------------------------------------
Mb1898|M.bovis_AF2122/97 -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
Rv1867|M.tuberculosis_H37Rv -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
MMAR_2746|M.marinum_M -VLAAVDSIRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQSL
MUL_3008|M.ulcerans_Agy99 -VLAAVDSMRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQPL
MAV_2851|M.avium_104 -VIEAVDSIRVVNILSAQYRDPGLLLGQRIGARDFGTLYTPVGGNVPQSL
MSMEG_3608|M.smegmatis_MC2_155 -VLQAVDSVRVVNLLSWRYRDPGLLLAGRIGAAGARTRYTGIGGNVPQTL
Mvan_3068|M.vanbaalenii_PYR-1 -LLEAVDAVRVVNLLSWRYRDPGLLLAQRIRADKAVTRYTGIGGNVPQTL
TH_1434|M.thermoresistible__bu --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 PVERRIDTVATPGILVIPRDNPASRIAEAMHISPARRISCPVGGNTPQYL
Mflv_4625|M.gilvum_PYR-GCK ---------------MIPRDNPASRIAEATGLTPDHRISCPVGGNTPQYL
Mb1898|M.bovis_AF2122/97 VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
Rv1867|M.tuberculosis_H37Rv VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
MMAR_2746|M.marinum_M VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MUL_3008|M.ulcerans_Agy99 VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MAV_2851|M.avium_104 VNQACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSVPMAE
MSMEG_3608|M.smegmatis_MC2_155 VNHACLDLQAGRAEVVLIAGAETWRTRSRLRARGVRPDWTRQDDTVPVAP
Mvan_3068|M.vanbaalenii_PYR-1 VNMACLDIQQGKADVVLIAGAETWRTRSRIRAAGRRPDWTKQDESVPSAP
TH_1434|M.thermoresistible__bu --------------------------------------------------
MAB_2042c|M.abscessus_ATCC_199 VEVLGGEIREGRADVVLVVGAESGHSARKLQGRALLD---SPPPPRSGDE
Mflv_4625|M.gilvum_PYR-GCK VEVLGRRIWRGVSDAALIVGAESGASARKVASGSALL---EPKPIAAQDE
Mb1898|M.bovis_AF2122/97 MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
Rv1867|M.tuberculosis_H37Rv MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
MMAR_2746|M.marinum_M VAGQDVPMAGESEIRIKLDRPAYVYPIFEQALRIANGESIEDHRSRVGRL
MUL_3008|M.ulcerans_Agy99 VAGQDVPMAGESEIRIKLDRAAYVYPMFEQALRIANGESIEDHRSRVGRL
MAV_2851|M.avium_104 VSGEDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRL
MSMEG_3608|M.smegmatis_MC2_155 GGDDNVPMAGDAENRIKLDRPAFVYPMFEQALRIAAGETPDEHRDRIGAL
Mvan_3068|M.vanbaalenii_PYR-1 GGDESVPMAAPSDIRINLDRPAYVYPMFEQALRIAAGETPDEHRRRIGEL
TH_1434|M.thermoresistible__bu -------MATPADIRIQLDRPSYVYPLFEQALRITAGEHPDAHRRRIGEL
MAB_2042c|M.abscessus_ATCC_199 SLGDARPGLSQAELSVGLSWPHEVYPIFESAIAARHGRDFDAQREWLGTL
Mflv_4625|M.gilvum_PYR-GCK SLGDTRPGLSEAEVGAGLHWPHEVYPIFESAIAARSGRTFDEQRRWLGDL
:: * . ***:**.*: *. : : :* *
Mb1898|M.bovis_AF2122/97 WARFSAVAADN-PHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMV
Rv1867|M.tuberculosis_H37Rv WARFSAVAADN-PHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMV
MMAR_2746|M.marinum_M WAGFNAVAVDN-PHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMV
MUL_3008|M.ulcerans_Agy99 WAGFNAVAVDN-PHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMV
MAV_2851|M.avium_104 WARFNAVAVDN-PHAWIRTPHSADDICRAGPHNRMISWPYTKLMNSNNMV
MSMEG_3608|M.smegmatis_MC2_155 WSRFSAVAARN-PHAWNRDAVTAQQITQVGPDNRMISWPYPKLMNSNNMV
Mvan_3068|M.vanbaalenii_PYR-1 WAQFSAVAADN-PHAWNREALTPEQIWQPSASNRMISWPYTKLMNSNNMV
TH_1434|M.thermoresistible__bu WARFSAVAADN-PHAWNRKALSAEQIWRPGPDNRMISWPYPKLMNSNNMV
MAB_2042c|M.abscessus_ATCC_199 MAPFTAEAARHPEQAWFPRARSATELSEVTAENRMVCLPYPKLLNSIMSV
Mflv_4625|M.gilvum_PYR-GCK MAPFTVEASRHLEQAWFPRARSADELSTVSPANRMVCEPYPKLLNSIIAV
: *.. * : :** . :. :: . ***:. **.**:** *
Mb1898|M.bovis_AF2122/97 DQGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTA
Rv1867|M.tuberculosis_H37Rv DQGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTA
MMAR_2746|M.marinum_M DQGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSIAERAELHQSPA
MUL_3008|M.ulcerans_Agy99 DQGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSSAERAELHQSPA
MAV_2851|M.avium_104 DQGAALVLTSVEQARRLKVPPERWVYPLAGTDAHDTASIAERHELHRSAA
MSMEG_3608|M.smegmatis_MC2_155 DQGAVLILTTVQMATYLQIPMDRWVFPYAGTDSHDTYAIGERDELHRSPA
Mvan_3068|M.vanbaalenii_PYR-1 DQGAVLIVASAETARHLQIPSDRWVFPYAGADSHDTYAIAERAEFHTSPA
TH_1434|M.thermoresistible__bu DQGAALILTSVQRARELRIPSERWVFPYAGTDAHDTYAIGERYRLDRSPA
MAB_2042c|M.abscessus_ATCC_199 DMAAAFILMAAEVADELGVARDRWVFPWSAATCNDVYFPVERPDLSRSSG
Mflv_4625|M.gilvum_PYR-GCK DMAAAFVIMAAEVAEELGVPSDRWVFPWSSATCNDVYFPVQRPDLGRSAG
* .*.::: :.: * * :. :***:* :.: .:*. :* : *..
Mb1898|M.bovis_AF2122/97 IRIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPL
Rv1867|M.tuberculosis_H37Rv IRIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPL
MMAR_2746|M.marinum_M IRIAGARALELAGLGIDDADYVDLYSCFPSAVQVAAHELGLPVDDADRPL
MUL_3008|M.ulcerans_Agy99 IRIAGARALELAGLGINDADYVDLYSCFPSAVQVAAHELGLPVDDADRPL
MAV_2851|M.avium_104 IRIAGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPL
MSMEG_3608|M.smegmatis_MC2_155 IRIAGRRVLELAGADIDAIDFVDVYSCFPSAVQVAAAELGLPTDDPARPL
Mvan_3068|M.vanbaalenii_PYR-1 IRIAGRRALELAGAGVDDMDLVDVYSCFPSAVQVAARELGLPVGKPDRPL
TH_1434|M.thermoresistible__bu IRIAGRRVLELAGLGIDDFRFVDVYSCFPSAVQVAAIELGLPLDDPARPL
MAB_2042c|M.abscessus_ATCC_199 IEVAARKALNAGRLTIDDIRWFDLYSCFPSAIEMTAEALDLDPLD-DRGL
Mflv_4625|M.gilvum_PYR-GCK IRAAGKAVLAASGLHIDDIRWFDFYSCFPSAVEAAIDALDLDPAD-DRGF
*. *. .* . :: .*.*******:: : *.* . * :
Mb1898|M.bovis_AF2122/97 TVTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSF
Rv1867|M.tuberculosis_H37Rv TVTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSF
MMAR_2746|M.marinum_M TVTGGLTFAGGPWNNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSI
MUL_3008|M.ulcerans_Agy99 TVTGGLTFAGGPWDNYVTHSIATMAELLAANPGRRGLITANGGYLTQHSI
MAV_2851|M.avium_104 TVTGGLTFAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSF
MSMEG_3608|M.smegmatis_MC2_155 TVTGGLTFAGGPWNNYVTHSIATMAEKLVAEPGTRGLITANGGYLTKHSF
Mvan_3068|M.vanbaalenii_PYR-1 TVTGGLTFAGGPWNNYVTHSIATMAERLAAQPGQRGLITANGGYLTKHSF
TH_1434|M.thermoresistible__bu TVTGGLTFAGGPWNNYVTHAIATMAERLIAAPGSRGLVTANGGYLTKHAF
MAB_2042c|M.abscessus_ATCC_199 TVTGGLPYHGGPGNNYVSHSIVEMVRRCRRDPTDVGLVTGLGWYSTKHSV
Mflv_4625|M.gilvum_PYR-GCK TVTGGLPYHGGPGNNYVSHSIVEMVRRCRSDPDAVGLVSGLGWYITKHSL
******.: *** .*** *:*. *.. * **::. * * *:*:.
Mb1898|M.bovis_AF2122/97 GVYGTEPPS-EFRWED---MQPAVD-REPTGDGLVEWEGIGTVEAWTTPV
Rv1867|M.tuberculosis_H37Rv GVYGTEPPS-EFRWED---MQPAVD-REPTGDGLVEWEGIGTVEAWTTPV
MMAR_2746|M.marinum_M GVYGTEPPA-EFCWED---VQPLVD-REPTRAALVGWDGVGAVEAWTTPF
MUL_3008|M.ulcerans_Agy99 GVYGTEPPA-EFRWED---VQPLVD-REPTRAALVGWDGVGAVEAWTTPF
MAV_2851|M.avium_104 GVYGTEPPA-EFRWED---TQSAVD-REPTTDAAVEWEGVGTVEAWTTPH
MSMEG_3608|M.smegmatis_MC2_155 GVYGTEPPEQEFRWED---VQSVVD-AEPTRKLAVEWVGTGTVESWTTPF
Mvan_3068|M.vanbaalenii_PYR-1 GVYGTEPPKHEFRWED---VQSEVD-REPTRTAVVEWSGVGTVESWTTPV
TH_1434|M.thermoresistible__bu GVYSTEPPPVEFRWED---VQSEVD-REPVRKVLVEWSGTGTVESWTTPF
MAB_2042c|M.abscessus_ATCC_199 GLWSATPPPTGWRLLDTAVEQAQIDSSRLGVAGVDEATGCATVDGYTVVY
Mflv_4625|M.gilvum_PYR-GCK GLWSATPPPTGWQTPDMADAQSAIDGTSLPVASPADASGEATIDGYTVVH
*::.: ** : * *. :* * .:::.:*.
Mb1898|M.bovis_AF2122/97 NRDGQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVA-PD
Rv1867|M.tuberculosis_H37Rv NRDGQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVA-PD
MMAR_2746|M.marinum_M TRDGQPEKAFVAVRTPTGARTLGVITDPASANATVHEDIAGAKVAIA-AD
MUL_3008|M.ulcerans_Agy99 TRDGQPEKAFVAVRTPTGARTLGVITDPASAHATVHEDIAGAKVAIA-AD
MAV_2851|M.avium_104 DREGEPEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVA-AD
MSMEG_3608|M.smegmatis_MC2_155 NRDGAPEKAFLAVRTPDGARTLAVITDESQAAATVREDIAGARVEVH-AD
Mvan_3068|M.vanbaalenii_PYR-1 DRDGAPEKAFLAVRTPEDARVLAVITDRAGAEATVRDDIAGAAVRVH-AD
TH_1434|M.thermoresistible__bu DRDGNPEKAFVAVRTPEDSRALAVIIDPSAAAVTVSEDVAGAPIRVH-AD
MAB_2042c|M.abscessus_ATCC_199 DRDGQPRWTPIIAHLSDGRRVVARSDDPQIAEAMGGEMYVGKTVCLRNTG
Mflv_4625|M.gilvum_PYR-GCK DRDQGPSWVPIFARMTDGRRVAARSDDAEVAVAMSRDMCVGHQVAVRQAD
*: * . : .: . . * . * . . : * : : ..
Mb1898|M.bovis_AF2122/97 GTATLR--
Rv1867|M.tuberculosis_H37Rv GTATLR--
MMAR_2746|M.marinum_M GNATLR--
MUL_3008|M.ulcerans_Agy99 GNATLR--
MAV_2851|M.avium_104 GSAALQ--
MSMEG_3608|M.smegmatis_MC2_155 GTATLL--
Mvan_3068|M.vanbaalenii_PYR-1 GTASLE--
TH_1434|M.thermoresistible__bu GTATLG--
MAB_2042c|M.abscessus_ATCC_199 SFTGFELP
Mflv_4625|M.gilvum_PYR-GCK GHVEFELS
. . :