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TVDPRTPVLIGYGQVNHRDDIDPAVRSVEPVDLMAAAVERAADAAVIEAVDSIRVVNILSAQYRDPGLLL GQRIGARDFGTLYTPVGGNVPQSLVNQACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSV PMAEVSGEDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRLWARFNAVAVDNPHAWI RTPHSADDICRAGPHNRMISWPYTKLMNSNNMVDQGAALVLTSVEQARRLKVPPERWVYPLAGTDAHDTA SIAERHELHRSAAIRIAGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPLTVTGGLT FAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSFGVYGTEPPAEFRWEDTQSAVDREPTTD AAVEWEGVGTVEAWTTPHDREGEPEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVAADGSA ALQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2851 | - | - | 100% (494) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_1076 | - | 1e-61 | 34.95% (515) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_2621 | - | 2e-15 | 29.28% (362) | thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1898 | - | 0.0 | 78.14% (494) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_3340 | - | 0.0 | 68.22% (494) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv1867 | - | 0.0 | 78.14% (494) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3826c | - | 1e-161 | 58.52% (499) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_2746 | - | 0.0 | 76.52% (494) | hypothetical protein MMAR_2746 |
| M. smegmatis MC2 155 | MSMEG_3608 | - | 0.0 | 69.33% (489) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_1434 | - | 1e-144 | 72.22% (342) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3008 | - | 0.0 | 75.51% (494) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3068 | - | 0.0 | 68.08% (495) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3340|M.gilvum_PYR-GCK MPIDPRTPVLIGYGQVNQRTED-----PSVEPVDLMAAAAREAADPR---
Mvan_3068|M.vanbaalenii_PYR-1 MPIDPRTPVLVGYGQVNQHDEN-----PDVEPVDLMVQAARAAADPR---
MSMEG_3608|M.smegmatis_MC2_155 --MN-RTPVLVGYGQVSQYDEN-----PATEPVDLMAEAARNAADPR---
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_2746|M.marinum_M MVVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
MUL_3008|M.ulcerans_Agy99 MAVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
Mb1898|M.bovis_AF2122/97 MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
Rv1867|M.tuberculosis_H37Rv MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
MAV_2851|M.avium_104 MTVDPRTPVLIGYGQVNHRDDIDPAV-RSVEPVDLMAAAVERAADAA---
MAB_3826c|M.abscessus_ATCC_199 MAFDPRTPVLVGTGQVNQRTDADTPFSEIPEPIDLMEQAARLAAGDAGAT
Mflv_3340|M.gilvum_PYR-GCK -VLEAVDAVRVVNLLSWRYRDPGLLLAERIGAAKAATRYTGIGGNVPQTL
Mvan_3068|M.vanbaalenii_PYR-1 -LLEAVDAVRVVNLLSWRYRDPGLLLAQRIRADKAVTRYTGIGGNVPQTL
MSMEG_3608|M.smegmatis_MC2_155 -VLQAVDSVRVVNLLSWRYRDPGLLLAGRIGAAGARTRYTGIGGNVPQTL
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_2746|M.marinum_M -VLAAVDSIRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQSL
MUL_3008|M.ulcerans_Agy99 -VLAAVDSMRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQPL
Mb1898|M.bovis_AF2122/97 -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
Rv1867|M.tuberculosis_H37Rv -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
MAV_2851|M.avium_104 -VIEAVDSIRVVNILSAQYRDPGLLLGQRIGARDFGTLYTPVGGNVPQSL
MAB_3826c|M.abscessus_ATCC_199 ELLGAIDTISVANIFSWRYRDPGVLLGERLGAVPKRTFYTGPSGNSPQLL
Mflv_3340|M.gilvum_PYR-GCK VNLACLDIQQGRNDVVLIAGAETWRSRTRTRAAGNKMQGTRQDESVPMAP
Mvan_3068|M.vanbaalenii_PYR-1 VNMACLDIQQGKADVVLIAGAETWRTRSRIRAAGRRPDWTKQDESVPSAP
MSMEG_3608|M.smegmatis_MC2_155 VNHACLDLQAGRAEVVLIAGAETWRTRSRLRARGVRPDWTRQDDTVPVAP
TH_1434|M.thermoresistible__bu --------------------------------------------------
MMAR_2746|M.marinum_M VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MUL_3008|M.ulcerans_Agy99 VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
Mb1898|M.bovis_AF2122/97 VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
Rv1867|M.tuberculosis_H37Rv VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
MAV_2851|M.avium_104 VNQACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSVPMAE
MAB_3826c|M.abscessus_ATCC_199 VNHAAADILAGDADVVLIGGAEMWRSRNKMMATGVQPTWTIQDESVAEAT
Mflv_3340|M.gilvum_PYR-GCK GSDENMPMAGPGDLKIGLDRPAYVYPMFETAVRIAAGETPDEHRRRIGEL
Mvan_3068|M.vanbaalenii_PYR-1 GGDESVPMAAPSDIRINLDRPAYVYPMFEQALRIAAGETPDEHRRRIGEL
MSMEG_3608|M.smegmatis_MC2_155 GGDDNVPMAGDAENRIKLDRPAFVYPMFEQALRIAAGETPDEHRDRIGAL
TH_1434|M.thermoresistible__bu -------MATPADIRIQLDRPSYVYPLFEQALRITAGEHPDAHRRRIGEL
MMAR_2746|M.marinum_M VAGQDVPMAGESEIRIKLDRPAYVYPIFEQALRIANGESIEDHRSRVGRL
MUL_3008|M.ulcerans_Agy99 VAGQDVPMAGESEIRIKLDRAAYVYPMFEQALRIANGESIEDHRSRVGRL
Mb1898|M.bovis_AF2122/97 MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
Rv1867|M.tuberculosis_H37Rv MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
MAV_2851|M.avium_104 VSGEDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRL
MAB_3826c|M.abscessus_ATCC_199 VLGGRMDQVGGAETAIGLISPGHVYPLFEEAIRIAGGVSIADHRAAMSQL
. .: * * ...***:** *:*:: * * :. *
Mflv_3340|M.gilvum_PYR-GCK WAQFSAVAAGNPHAWSQEARTAEEIYEPSPKNRMVSWPYTKLMNSNNMVD
Mvan_3068|M.vanbaalenii_PYR-1 WAQFSAVAADNPHAWNREALTPEQIWQPSASNRMISWPYTKLMNSNNMVD
MSMEG_3608|M.smegmatis_MC2_155 WSRFSAVAARNPHAWNRDAVTAQQITQVGPDNRMISWPYPKLMNSNNMVD
TH_1434|M.thermoresistible__bu WARFSAVAADNPHAWNRKALSAEQIWRPGPDNRMISWPYPKLMNSNNMVD
MMAR_2746|M.marinum_M WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
MUL_3008|M.ulcerans_Agy99 WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
Mb1898|M.bovis_AF2122/97 WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
Rv1867|M.tuberculosis_H37Rv WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
MAV_2851|M.avium_104 WARFNAVAVDNPHAWIRTPHSADDICRAGPHNRMISWPYTKLMNSNNMVD
MAB_3826c|M.abscessus_ATCC_199 WQRFNAVAVTNGHAWSNDAYTAEEIATPGPDNRWISSPYTKLMNSNNMVE
* *.***. * *** . . :.::* .. ** :* **.*********:
Mflv_3340|M.gilvum_PYR-GCK QGAVLILTSVEKAQHLQIPSERWVFPYAGADAHDTYAIGERAEFHASPAI
Mvan_3068|M.vanbaalenii_PYR-1 QGAVLIVASAETARHLQIPSDRWVFPYAGADSHDTYAIAERAEFHTSPAI
MSMEG_3608|M.smegmatis_MC2_155 QGAVLILTTVQMATYLQIPMDRWVFPYAGTDSHDTYAIGERDELHRSPAI
TH_1434|M.thermoresistible__bu QGAALILTSVQRARELRIPSERWVFPYAGTDAHDTYAIGERYRLDRSPAI
MMAR_2746|M.marinum_M QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSIAERAELHQSPAI
MUL_3008|M.ulcerans_Agy99 QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSSAERAELHQSPAI
Mb1898|M.bovis_AF2122/97 QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
Rv1867|M.tuberculosis_H37Rv QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
MAV_2851|M.avium_104 QGAALVLTSVEQARRLKVPPERWVYPLAGTDAHDTASIAERHELHRSAAI
MAB_3826c|M.abscessus_ATCC_199 QGAVVLLTSVETALRLGISKDRWIFPLAGAQANDTFALSERHELHRSPAI
***.:::::.: * * :. :**::* :*::::** : .:* .:. *.**
Mflv_3340|M.gilvum_PYR-GCK RIAGTRALELAGAGVDDMDLIDVYSCFPSAVQVAARELGLPIGDPDRPLT
Mvan_3068|M.vanbaalenii_PYR-1 RIAGRRALELAGAGVDDMDLVDVYSCFPSAVQVAARELGLPVGKPDRPLT
MSMEG_3608|M.smegmatis_MC2_155 RIAGRRVLELAGADIDAIDFVDVYSCFPSAVQVAAAELGLPTDDPARPLT
TH_1434|M.thermoresistible__bu RIAGRRVLELAGLGIDDFRFVDVYSCFPSAVQVAAIELGLPLDDPARPLT
MMAR_2746|M.marinum_M RIAGARALELAGLGIDDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
MUL_3008|M.ulcerans_Agy99 RIAGARALELAGLGINDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
Mb1898|M.bovis_AF2122/97 RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
Rv1867|M.tuberculosis_H37Rv RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
MAV_2851|M.avium_104 RIAGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPLT
MAB_3826c|M.abscessus_ATCC_199 RLAGRRAFEIAGLGTDDVELVDIYSCFPSAVQVAAAELGLALDDPARPLT
*:** *.:::** . : :*:************ **** ... ****
Mflv_3340|M.gilvum_PYR-GCK VTGGLTFAGGPWNNYVTHSIATMAEQLIARPGTRGLITANGGYLTKHSFG
Mvan_3068|M.vanbaalenii_PYR-1 VTGGLTFAGGPWNNYVTHSIATMAERLAAQPGQRGLITANGGYLTKHSFG
MSMEG_3608|M.smegmatis_MC2_155 VTGGLTFAGGPWNNYVTHSIATMAEKLVAEPGTRGLITANGGYLTKHSFG
TH_1434|M.thermoresistible__bu VTGGLTFAGGPWNNYVTHAIATMAERLIAAPGSRGLVTANGGYLTKHAFG
MMAR_2746|M.marinum_M VTGGLTFAGGPWNNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSIG
MUL_3008|M.ulcerans_Agy99 VTGGLTFAGGPWDNYVTHSIATMAELLAANPGRRGLITANGGYLTQHSIG
Mb1898|M.bovis_AF2122/97 VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
Rv1867|M.tuberculosis_H37Rv VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
MAV_2851|M.avium_104 VTGGLTFAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSFG
MAB_3826c|M.abscessus_ATCC_199 VTGGLTFAGGPWCNYVTHSIATMAERLRERPGAKGLITANGGYLTKHAFG
************ *** *:****** * ** :**:********:*::*
Mflv_3340|M.gilvum_PYR-GCK VYGTEPPTHEFRWEDVQSEVDAEPTRTALVDWSGVGTVETWTTPVDRDGN
Mvan_3068|M.vanbaalenii_PYR-1 VYGTEPPKHEFRWEDVQSEVDREPTRTAVVEWSGVGTVESWTTPVDRDGA
MSMEG_3608|M.smegmatis_MC2_155 VYGTEPPEQEFRWEDVQSVVDAEPTRKLAVEWVGTGTVESWTTPFNRDGA
TH_1434|M.thermoresistible__bu VYSTEPPPVEFRWEDVQSEVDREPVRKVLVEWSGTGTVESWTTPFDRDGN
MMAR_2746|M.marinum_M VYGTEPPA-EFCWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
MUL_3008|M.ulcerans_Agy99 VYGTEPPA-EFRWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
Mb1898|M.bovis_AF2122/97 VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
Rv1867|M.tuberculosis_H37Rv VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
MAV_2851|M.avium_104 VYGTEPPA-EFRWEDTQSAVDREPTTDAAVEWEGVGTVEAWTTPHDREGE
MAB_3826c|M.abscessus_ATCC_199 IYGTEPPASGFAYEDVQADVDQEPRTEAADGYTGTAAVEAWTVNYGRDGS
:*.**** * :** *. ** ** : * .:**:**. *:*
Mflv_3340|M.gilvum_PYR-GCK PEKAFLAVRTPEDARVLAVITDPAGAETTVRDDIAGAQVRVEEDGTASLV
Mvan_3068|M.vanbaalenii_PYR-1 PEKAFLAVRTPEDARVLAVITDRAGAEATVRDDIAGAAVRVHADGTASLE
MSMEG_3608|M.smegmatis_MC2_155 PEKAFLAVRTPDGARTLAVITDESQAAATVREDIAGARVEVHADGTATLL
TH_1434|M.thermoresistible__bu PEKAFVAVRTPEDSRALAVIIDPSAAAVTVSEDVAGAPIRVHADGTATLG
MMAR_2746|M.marinum_M PEKAFVAVRTPTGARTLGVITDPASANATVHEDIAGAKVAIAADGNATLR
MUL_3008|M.ulcerans_Agy99 PEKAFVAVRTPTGARTLGVITDPASAHATVHEDIAGAKVAIAADGNATLR
Mb1898|M.bovis_AF2122/97 PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
Rv1867|M.tuberculosis_H37Rv PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
MAV_2851|M.avium_104 PEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVAADGSAALQ
MAB_3826c|M.abscessus_ATCC_199 PFQTFVSVRTPTGARTFAKIDDRDASAHIADTDIAGASIEVAADGSARLN
* ::*::**** .:* :. : * . *:.*. : : **.* *