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M. bovis AF2122 / 97 Mb1898 (-)

annotation: acetyl-CoA acetyltransferase
coordinates: 2105973 - 2107457
length: 494

MPVDPRTPVLIGYGQVNHRGDIDAEKQSIEPVDLMAAAARKAADSTVLEAVDSIRVVHMLSAHYRNPGQL
LGERIKARTFTTGYSGVGGNMPQSLVNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDES
VPLPDMAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGELWARFSAVAADNPHAW
IRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVDQGAALLLTSVERATRLRIPAERWVYPQAGTDAHDT
PAVADRHRLHRSTAIRIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLTVTGGL
TFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFGVYGTEPPSEFRWEDMQPAVDREPTG
DGLVEWEGIGTVEAWTTPVNRDGQPEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGT
ATLR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1898--100% (494)acetyl-CoA acetyltransferase
M. bovis AF2122 / 97Mb2813cltp13e-0523.11% (238) lipid-transfer protein
M. bovis AF2122 / 97Mb0882fadA9e-0528.97% (145) acetyl-CoA acetyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3340-0.070.04% (494) acetyl-CoA acetyltransferase
M. tuberculosis H37RvRv1867-0.0100.00% (494) acetyl-CoA acetyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3826c-1e-15657.31% (499) acetyl-CoA acetyltransferase
M. marinum MMMAR_2746-0.078.95% (494) hypothetical protein MMAR_2746
M. avium 104MAV_2851-0.078.14% (494) acetyl-CoA acetyltransferase
M. smegmatis MC2 155MSMEG_3608-0.070.35% (489) acetyl-CoA acetyltransferase
M. thermoresistible (build 8)TH_1434-1e-15073.68% (342) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_3008-0.077.94% (494) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1Mvan_3068-0.068.83% (494) acetyl-CoA acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3340|M.gilvum_PYR-GCK          MPIDPRTPVLIGYGQVNQRTED-----PSVEPVDLMAAAAREAADPR---
Mvan_3068|M.vanbaalenii_PYR-1       MPIDPRTPVLVGYGQVNQHDEN-----PDVEPVDLMVQAARAAADPR---
MSMEG_3608|M.smegmatis_MC2_155      --MN-RTPVLVGYGQVSQYDEN-----PATEPVDLMAEAARNAADPR---
TH_1434|M.thermoresistible__bu      --------------------------------------------------
Mb1898|M.bovis_AF2122/97            MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
Rv1867|M.tuberculosis_H37Rv         MPVDPRTPVLIGYGQVNHRGDIDAEK-QSIEPVDLMAAAARKAADST---
MMAR_2746|M.marinum_M               MVVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
MUL_3008|M.ulcerans_Agy99           MAVDPRTPVLIGYGQVNYRDEIDPTM-PSVEPVDLMLAAAQQAADSR---
MAV_2851|M.avium_104                MTVDPRTPVLIGYGQVNHRDDIDPAV-RSVEPVDLMAAAVERAADAA---
MAB_3826c|M.abscessus_ATCC_199      MAFDPRTPVLVGTGQVNQRTDADTPFSEIPEPIDLMEQAARLAAGDAGAT
                                                                                      

Mflv_3340|M.gilvum_PYR-GCK          -VLEAVDAVRVVNLLSWRYRDPGLLLAERIGAAKAATRYTGIGGNVPQTL
Mvan_3068|M.vanbaalenii_PYR-1       -LLEAVDAVRVVNLLSWRYRDPGLLLAQRIRADKAVTRYTGIGGNVPQTL
MSMEG_3608|M.smegmatis_MC2_155      -VLQAVDSVRVVNLLSWRYRDPGLLLAGRIGAAGARTRYTGIGGNVPQTL
TH_1434|M.thermoresistible__bu      --------------------------------------------------
Mb1898|M.bovis_AF2122/97            -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
Rv1867|M.tuberculosis_H37Rv         -VLEAVDSIRVVHMLSAHYRNPGQLLGERIKARTFTTGYSGVGGNMPQSL
MMAR_2746|M.marinum_M               -VLAAVDSIRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQSL
MUL_3008|M.ulcerans_Agy99           -VLAAVDSMRVVRVLSAHYRNPGQLLGERLQASGFTTSYSSVGGNTPQPL
MAV_2851|M.avium_104                -VIEAVDSIRVVNILSAQYRDPGLLLGQRIGARDFGTLYTPVGGNVPQSL
MAB_3826c|M.abscessus_ATCC_199      ELLGAIDTISVANIFSWRYRDPGVLLGERLGAVPKRTFYTGPSGNSPQLL
                                                                                      

Mflv_3340|M.gilvum_PYR-GCK          VNLACLDIQQGRNDVVLIAGAETWRSRTRTRAAGNKMQGTRQDESVPMAP
Mvan_3068|M.vanbaalenii_PYR-1       VNMACLDIQQGKADVVLIAGAETWRTRSRIRAAGRRPDWTKQDESVPSAP
MSMEG_3608|M.smegmatis_MC2_155      VNHACLDLQAGRAEVVLIAGAETWRTRSRLRARGVRPDWTRQDDTVPVAP
TH_1434|M.thermoresistible__bu      --------------------------------------------------
Mb1898|M.bovis_AF2122/97            VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
Rv1867|M.tuberculosis_H37Rv         VNRACLDIQRGRAGVVLLAGAETWRTRTGLRAKGSKLEWTVQDESVPLPD
MMAR_2746|M.marinum_M               VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MUL_3008|M.ulcerans_Agy99           VSQACLDVQRGRAGVVLIAGAETWRTRTGLKSKGARLTWTLQDESVPLPR
MAV_2851|M.avium_104                VNQACLDIQRGRANVVLLAGAETWRTRRGLRAKGGKLVWTEQDRSVPMAE
MAB_3826c|M.abscessus_ATCC_199      VNHAAADILAGDADVVLIGGAEMWRSRNKMMATGVQPTWTIQDESVAEAT
                                                                                      

Mflv_3340|M.gilvum_PYR-GCK          GSDENMPMAGPGDLKIGLDRPAYVYPMFETAVRIAAGETPDEHRRRIGEL
Mvan_3068|M.vanbaalenii_PYR-1       GGDESVPMAAPSDIRINLDRPAYVYPMFEQALRIAAGETPDEHRRRIGEL
MSMEG_3608|M.smegmatis_MC2_155      GGDDNVPMAGDAENRIKLDRPAFVYPMFEQALRIAAGETPDEHRDRIGAL
TH_1434|M.thermoresistible__bu      -------MATPADIRIQLDRPSYVYPLFEQALRITAGEHPDAHRRRIGEL
Mb1898|M.bovis_AF2122/97            MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
Rv1867|M.tuberculosis_H37Rv         MAGDDVPMAGAAELRINLDRPAYVYPIFEQALRIAYGESIENHRKRIGEL
MMAR_2746|M.marinum_M               VAGQDVPMAGESEIRIKLDRPAYVYPIFEQALRIANGESIEDHRSRVGRL
MUL_3008|M.ulcerans_Agy99           VAGQDVPMAGESEIRIKLDRAAYVYPMFEQALRIANGESIEDHRSRVGRL
MAV_2851|M.avium_104                VSGEDVAMAGEAEIRISLDRPAYVYPLFEQALRVSTGESVEDHLTRIGRL
MAB_3826c|M.abscessus_ATCC_199      VLGGRMDQVGGAETAIGLISPGHVYPLFEEAIRIAGGVSIADHRAAMSQL
                                            .  .:  * *  ...***:** *:*:: *     *   :. *

Mflv_3340|M.gilvum_PYR-GCK          WAQFSAVAAGNPHAWSQEARTAEEIYEPSPKNRMVSWPYTKLMNSNNMVD
Mvan_3068|M.vanbaalenii_PYR-1       WAQFSAVAADNPHAWNREALTPEQIWQPSASNRMISWPYTKLMNSNNMVD
MSMEG_3608|M.smegmatis_MC2_155      WSRFSAVAARNPHAWNRDAVTAQQITQVGPDNRMISWPYPKLMNSNNMVD
TH_1434|M.thermoresistible__bu      WARFSAVAADNPHAWNRKALSAEQIWRPGPDNRMISWPYPKLMNSNNMVD
Mb1898|M.bovis_AF2122/97            WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
Rv1867|M.tuberculosis_H37Rv         WARFSAVAADNPHAWIRNPVTADEIWQPGPQNRMVSWPYTKLMNSNNMVD
MMAR_2746|M.marinum_M               WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
MUL_3008|M.ulcerans_Agy99           WAGFNAVAVDNPHAWIRTPMTAEQICRPGPQNRMISWPYTKLMNSNNMVD
MAV_2851|M.avium_104                WARFNAVAVDNPHAWIRTPHSADDICRAGPHNRMISWPYTKLMNSNNMVD
MAB_3826c|M.abscessus_ATCC_199      WQRFNAVAVTNGHAWSNDAYTAEEIATPGPDNRWISSPYTKLMNSNNMVE
                                    *  *.***. * *** . . :.::*   .. ** :* **.*********:

Mflv_3340|M.gilvum_PYR-GCK          QGAVLILTSVEKAQHLQIPSERWVFPYAGADAHDTYAIGERAEFHASPAI
Mvan_3068|M.vanbaalenii_PYR-1       QGAVLIVASAETARHLQIPSDRWVFPYAGADSHDTYAIAERAEFHTSPAI
MSMEG_3608|M.smegmatis_MC2_155      QGAVLILTTVQMATYLQIPMDRWVFPYAGTDSHDTYAIGERDELHRSPAI
TH_1434|M.thermoresistible__bu      QGAALILTSVQRARELRIPSERWVFPYAGTDAHDTYAIGERYRLDRSPAI
Mb1898|M.bovis_AF2122/97            QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
Rv1867|M.tuberculosis_H37Rv         QGAALLLTSVERATRLRIPAERWVYPQAGTDAHDTPAVADRHRLHRSTAI
MMAR_2746|M.marinum_M               QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSIAERAELHQSPAI
MUL_3008|M.ulcerans_Agy99           QGAALILTSVEQATRLRVPTERWVYPQTGTEAHDTFSSAERAELHQSPAI
MAV_2851|M.avium_104                QGAALVLTSVEQARRLKVPPERWVYPLAGTDAHDTASIAERHELHRSAAI
MAB_3826c|M.abscessus_ATCC_199      QGAVVLLTSVETALRLGISKDRWIFPLAGAQANDTFALSERHELHRSPAI
                                    ***.:::::.: *  * :. :**::* :*::::** : .:* .:. *.**

Mflv_3340|M.gilvum_PYR-GCK          RIAGTRALELAGAGVDDMDLIDVYSCFPSAVQVAARELGLPIGDPDRPLT
Mvan_3068|M.vanbaalenii_PYR-1       RIAGRRALELAGAGVDDMDLVDVYSCFPSAVQVAARELGLPVGKPDRPLT
MSMEG_3608|M.smegmatis_MC2_155      RIAGRRVLELAGADIDAIDFVDVYSCFPSAVQVAAAELGLPTDDPARPLT
TH_1434|M.thermoresistible__bu      RIAGRRVLELAGLGIDDFRFVDVYSCFPSAVQVAAIELGLPLDDPARPLT
Mb1898|M.bovis_AF2122/97            RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
Rv1867|M.tuberculosis_H37Rv         RIAGARALELAGLGLDDIEYVDLYSCFPSAVQVAAIELGLDTDDPARPLT
MMAR_2746|M.marinum_M               RIAGARALELAGLGIDDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
MUL_3008|M.ulcerans_Agy99           RIAGARALELAGLGINDADYVDLYSCFPSAVQVAAHELGLPVDDADRPLT
MAV_2851|M.avium_104                RIAGARALQLAGLGIDDVDHVDLYSCFPSAVQVAAAELGLGLDDPARPLT
MAB_3826c|M.abscessus_ATCC_199      RLAGRRAFEIAGLGTDDVELVDIYSCFPSAVQVAAAELGLALDDPARPLT
                                    *:** *.:::** . :    :*:************ ****  ... ****

Mflv_3340|M.gilvum_PYR-GCK          VTGGLTFAGGPWNNYVTHSIATMAEQLIARPGTRGLITANGGYLTKHSFG
Mvan_3068|M.vanbaalenii_PYR-1       VTGGLTFAGGPWNNYVTHSIATMAERLAAQPGQRGLITANGGYLTKHSFG
MSMEG_3608|M.smegmatis_MC2_155      VTGGLTFAGGPWNNYVTHSIATMAEKLVAEPGTRGLITANGGYLTKHSFG
TH_1434|M.thermoresistible__bu      VTGGLTFAGGPWNNYVTHAIATMAERLIAAPGSRGLVTANGGYLTKHAFG
Mb1898|M.bovis_AF2122/97            VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
Rv1867|M.tuberculosis_H37Rv         VTGGLTFAGGPWSNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSFG
MMAR_2746|M.marinum_M               VTGGLTFAGGPWNNYVTHSIATMAELLAANPGRRGLITANGGYLTKHSIG
MUL_3008|M.ulcerans_Agy99           VTGGLTFAGGPWDNYVTHSIATMAELLAANPGRRGLITANGGYLTQHSIG
MAV_2851|M.avium_104                VTGGLTFAGGPWSNYVMHSIATMAELLVANPGRRGLITANGGYLTKHSFG
MAB_3826c|M.abscessus_ATCC_199      VTGGLTFAGGPWCNYVTHSIATMAERLRERPGAKGLITANGGYLTKHAFG
                                    ************ *** *:****** *   ** :**:********:*::*

Mflv_3340|M.gilvum_PYR-GCK          VYGTEPPTHEFRWEDVQSEVDAEPTRTALVDWSGVGTVETWTTPVDRDGN
Mvan_3068|M.vanbaalenii_PYR-1       VYGTEPPKHEFRWEDVQSEVDREPTRTAVVEWSGVGTVESWTTPVDRDGA
MSMEG_3608|M.smegmatis_MC2_155      VYGTEPPEQEFRWEDVQSVVDAEPTRKLAVEWVGTGTVESWTTPFNRDGA
TH_1434|M.thermoresistible__bu      VYSTEPPPVEFRWEDVQSEVDREPVRKVLVEWSGTGTVESWTTPFDRDGN
Mb1898|M.bovis_AF2122/97            VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
Rv1867|M.tuberculosis_H37Rv         VYGTEPPS-EFRWEDMQPAVDREPTGDGLVEWEGIGTVEAWTTPVNRDGQ
MMAR_2746|M.marinum_M               VYGTEPPA-EFCWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
MUL_3008|M.ulcerans_Agy99           VYGTEPPA-EFRWEDVQPLVDREPTRAALVGWDGVGAVEAWTTPFTRDGQ
MAV_2851|M.avium_104                VYGTEPPA-EFRWEDTQSAVDREPTTDAAVEWEGVGTVEAWTTPHDREGE
MAB_3826c|M.abscessus_ATCC_199      IYGTEPPASGFAYEDVQADVDQEPRTEAADGYTGTAAVEAWTVNYGRDGS
                                    :*.****   * :** *. ** **       : * .:**:**.   *:* 

Mflv_3340|M.gilvum_PYR-GCK          PEKAFLAVRTPEDARVLAVITDPAGAETTVRDDIAGAQVRVEEDGTASLV
Mvan_3068|M.vanbaalenii_PYR-1       PEKAFLAVRTPEDARVLAVITDRAGAEATVRDDIAGAAVRVHADGTASLE
MSMEG_3608|M.smegmatis_MC2_155      PEKAFLAVRTPDGARTLAVITDESQAAATVREDIAGARVEVHADGTATLL
TH_1434|M.thermoresistible__bu      PEKAFVAVRTPEDSRALAVIIDPSAAAVTVSEDVAGAPIRVHADGTATLG
Mb1898|M.bovis_AF2122/97            PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
Rv1867|M.tuberculosis_H37Rv         PEKAFLAVRTPDGSRSLAVITDPASVQATVREDIAGVKVAVAPDGTATLR
MMAR_2746|M.marinum_M               PEKAFVAVRTPTGARTLGVITDPASANATVHEDIAGAKVAIAADGNATLR
MUL_3008|M.ulcerans_Agy99           PEKAFVAVRTPTGARTLGVITDPASAHATVHEDIAGAKVAIAADGNATLR
MAV_2851|M.avium_104                PEKAFLAVRTPDGSRALAVVTDRAAAQATVREDIGGAKVAVAADGSAALQ
MAB_3826c|M.abscessus_ATCC_199      PFQTFVSVRTPTGARTFAKIDDRDASAHIADTDIAGASIEVAADGSARLN
                                    * ::*::**** .:* :. : *       .  *:.*. : :  **.* *