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MTTSPDDEAVTALALAAADGDARAFEAFIKATQQDVWRFVAYLSDAGSADDLTQETFLRAIGAIRRFGGR SSARTWLLAIARRVVADHIRHLQARPRAAHGVDPELLLDRGRRARGFEDLVEVTTMIAQLTSDQREALLL TQLLGLSYTDAAAVCGCPVGTIRSRVARARDALLADNERDDLTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3051 | sigC | - | 100% (184) | RNA polymerase sigma factor, SigC |
| M. marinum M | MMAR_0265 | sigC_1 | 5e-53 | 59.77% (174) | ECF subfamily RNA polymerase sigma factor |
| M. marinum M | MMAR_4216 | sigE | 2e-09 | 27.22% (180) | alternative RNA polymerase sigma factor SigE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2095 | sigC | 5e-81 | 83.52% (182) | RNA polymerase sigma factor SigC |
| M. gilvum PYR-GCK | Mflv_2200 | - | 1e-10 | 28.96% (183) | RNA polymerase sigma factor SigE |
| M. tuberculosis H37Rv | Rv2069 | sigC | 5e-81 | 83.52% (182) | RNA polymerase sigma factor SigC |
| M. leprae Br4923 | MLBr_01448 | - | 4e-75 | 78.26% (184) | RNA polymerase sigma factor SigC |
| M. abscessus ATCC 19977 | MAB_3428c | - | 9e-60 | 61.96% (184) | RNA polymerase sigma-C factor |
| M. avium 104 | MAV_2426 | - | 3e-81 | 83.70% (184) | RNA polymerase sigma factor SigC |
| M. smegmatis MC2 155 | MSMEG_6931 | - | 2e-11 | 32.54% (169) | RNA polymerase sigma-70 factor |
| M. thermoresistible (build 8) | TH_1729 | sigC | 5e-59 | 64.25% (179) | PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC |
| M. ulcerans Agy99 | MUL_2295 | sigC | 1e-100 | 100.00% (184) | RNA polymerase sigma factor SigC |
| M. vanbaalenii PYR-1 | Mvan_2297 | - | 1e-11 | 31.03% (145) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 MTPGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAI
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 AAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPAS
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 ASGVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVA
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK ---------------------------------MTEGARTDTVRTARIDS
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 RERVGSRRPGSSDATADAGFAAWAADAPAGRRRGHLRPINRAAPDPTASS
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK ARSRNENASARVAEHDGSPQGGPHHHLEDPTTTTQAPTSSVSAAAPVAAP
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3051|M.marinum_M -----------------MTTSPDDEA-VTALALAAADGDARAFEAFIKAT
MUL_2295|M.ulcerans_Agy99 ---------------MPMTTSPDDEA-VTALALAAADGDARAFEAFIKAT
MLBr_01448|M.leprae_Br4923 -----------------MIASSGDEA-VTDLALAAARGSKRALEAFIKAT
MAV_2426|M.avium_104 TTTRRRIGKPAQLRWLGMIAPSDDEA-VTELALSAARGNARALEAFIKAT
Mb2095|M.bovis_AF2122/97 ----------------MTATASDDEA-VTALALSAAKGNGRALEAFIKAT
Rv2069|M.tuberculosis_H37Rv ----------------MTATASDDEA-VTALALSAAKGNGRALEAFIKAT
MAB_3428c|M.abscessus_ATCC_199 -----------------MATGTDDEQ-LLELALSAGRGDQSALESLVKAT
TH_1729|M.thermoresistible__bu ------------------VGLRDDDR-VTRLALAAGRGDPAALEQFIRAT
MSMEG_6931|M.smegmatis_MC2_155 ------------MGRGEFAGAAHTRS-DAELLAAHVAGDRYAFEELVLRH
Mflv_2200|M.gilvum_PYR-GCK VAAPVSMAHREQFTEAEWVEPTDELTGTAVFDATGDKAAMPSWDELVRQH
Mvan_2297|M.vanbaalenii_PYR-1 ----------MRRSSIQWNQQPDNLFGGPVMDSPPEDTVLQRFERDVLPL
: . : :
MMAR_3051|M.marinum_M QQDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLAIA
MUL_2295|M.ulcerans_Agy99 QQDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLAIA
MLBr_01448|M.leprae_Br4923 QQDVWRFVAYLS-DVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLAIA
MAV_2426|M.avium_104 QQDVWRFVAYLC-DAGSADDLTQETFLRAIGAIERFSGRSSARTWLLSIA
Mb2095|M.bovis_AF2122/97 QQDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIA
Rv2069|M.tuberculosis_H37Rv QQDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIA
MAB_3428c|M.abscessus_ATCC_199 QGDVWRFVAYLA-DSGVADDLTQETYLRALGALPRFAGRSTVRTWLLSIA
TH_1729|M.thermoresistible__bu QRDVWRTVAYLA-DPGSADDLTQETFLRAIRSLPKFNGRSSARTWLLSIA
MSMEG_6931|M.smegmatis_MC2_155 HRQLRRLAYLTSNHLDDADDAVQEALLKAHRTAATFRFDCAVSSWLYRIV
Mflv_2200|M.gilvum_PYR-GCK ADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPG-TFEGWLHRIT
Mvan_2297|M.vanbaalenii_PYR-1 LDQLYRAARRYTGSVADAEDLVQETMVKAYGGFHRFEDGTNVRAWLLRIM
: * . *:* .**: ::. : ** *
MMAR_3051|M.marinum_M RRVVADHIRHLQARPRAAHGVDPELLLDRGRRARG-------------FE
MUL_2295|M.ulcerans_Agy99 RRVVADHIRHLQARPRAAHGVDPELLLDRGRRARG-------------FE
MLBr_01448|M.leprae_Br4923 RRVVADHIRRAQTRPRTTFDGYPERMLNADRHARG-------------FE
MAV_2426|M.avium_104 RRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARG-------------FE
Mb2095|M.bovis_AF2122/97 RHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARG-------------FE
Rv2069|M.tuberculosis_H37Rv RHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARG-------------FE
MAB_3428c|M.abscessus_ATCC_199 RRVVADHIRHLKSRPRIAHGADLEEASLR-RPTHR-------------FE
TH_1729|M.thermoresistible__bu RRVVVDQIRHNQSRPRTSYAVDVHTVLDKRRPDGR-------------FE
MSMEG_6931|M.smegmatis_MC2_155 VNACLDRLRRTRTQPSATHYVELGHVNHLRDPAADPA---------PRVT
Mflv_2200|M.gilvum_PYR-GCK TNLFLDMVRRRGRIRMEALPEDYDRVPADEPNPEQIY---------HDSR
Mvan_2297|M.vanbaalenii_PYR-1 TNTWIKSYRRAQCRPEEVLSEDITDAQLAGHGRHSSTGLPSAELAALEAL
. . *:
MMAR_3051|M.marinum_M DLVEVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRVAR
MUL_2295|M.ulcerans_Agy99 DLVEVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRVAR
MLBr_01448|M.leprae_Br4923 DLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVAR
MAV_2426|M.avium_104 DLVEVTTMIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVAR
Mb2095|M.bovis_AF2122/97 DLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVAR
Rv2069|M.tuberculosis_H37Rv DLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVAR
MAB_3428c|M.abscessus_ATCC_199 ELVELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTIRSRVAR
TH_1729|M.thermoresistible__bu DIVEIKLLLDGLDTDRRHALLLTQVLGLSYAEAAEVCGCAVGTIRSRVAR
MSMEG_6931|M.smegmatis_MC2_155 TAITVERALLQLPVDQRAAVVAVDMQGYSVAETARLLGVAEGTIKSRCAR
Mflv_2200|M.gilvum_PYR-GCK LGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHR
Mvan_2297|M.vanbaalenii_PYR-1 GDDEVRDALGRLREDQRLVVYYADVEGLRYKEIALILDIPVGTVMSRLHR
: : * : * .: :: * : . . **: ** *
MMAR_3051|M.marinum_M ARDALLADNERDDLTG--------------
MUL_2295|M.ulcerans_Agy99 ARDALLADNERDDLTG--------------
MLBr_01448|M.leprae_Br4923 ARDALLADTEHNHLTG--------------
MAV_2426|M.avium_104 ARDALLADGERNDLTG--------------
Mb2095|M.bovis_AF2122/97 ARDALLADAEPDDLTG--------------
Rv2069|M.tuberculosis_H37Rv ARDALLADAEPDDLTG--------------
MAB_3428c|M.abscessus_ATCC_199 ARDELIGWAEPENLTG--------------
TH_1729|M.thermoresistible__bu ARDDLLQQARPVDRTG--------------
MSMEG_6931|M.smegmatis_MC2_155 ARAKLARTLQYFDGDEPQPATSAHRGAAHP
Mflv_2200|M.gilvum_PYR-GCK GRQALRDHLARHSDVGAGRDTAKSA-----
Mvan_2297|M.vanbaalenii_PYR-1 GRRALRSLLVDVATARGYLRDAAAA-----
.* *